LOCUS       NM_001011964            2400 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Rattus norvegicus MAPK associated protein 1 (Mapkap1), mRNA.
ACCESSION   NM_001011964 XM_216040
VERSION     NM_001011964.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2400)
  AUTHORS   Chen,S., Lu,F.F., Seeman,P. and Liu,F.
  TITLE     Quantitative proteomic analysis of human substantia nigra in
            Alzheimer's disease, Huntington's disease and Multiple sclerosis
  JOURNAL   Neurochem Res 37 (12), 2805-2813 (2012)
   PUBMED   22926577
REFERENCE   2  (bases 1 to 2400)
  AUTHORS   Laplante,M. and Sabatini,D.M.
  TITLE     mTOR signaling in growth control and disease
  JOURNAL   Cell 149 (2), 274-293 (2012)
   PUBMED   22500797
  REMARK    Review article
REFERENCE   3  (bases 1 to 2400)
  AUTHORS   Murata,H., Sakaguchi,M., Jin,Y., Sakaguchi,Y., Futami,J.,
            Yamada,H., Kataoka,K. and Huh,N.H.
  TITLE     A new cytosolic pathway from a Parkinson disease-associated kinase,
            BRPK/PINK1: activation of AKT via mTORC2
  JOURNAL   J Biol Chem 286 (9), 7182-7189 (2011)
   PUBMED   21177249
REFERENCE   4  (bases 1 to 2400)
  AUTHORS   Ma,X.M. and Blenis,J.
  TITLE     Molecular mechanisms of mTOR-mediated translational control
  JOURNAL   Nat Rev Mol Cell Biol 10 (5), 307-318 (2009)
   PUBMED   19339977
  REMARK    Review article
REFERENCE   5  (bases 1 to 2400)
  AUTHORS   Schroder,W.A., Buck,M., Cloonan,N., Hancock,J.F., Suhrbier,A.,
            Sculley,T. and Bushell,G.
  TITLE     Human Sin1 contains Ras-binding and pleckstrin homology domains and
            suppresses Ras signalling
  JOURNAL   Cell Signal 19 (6), 1279-1289 (2007)
   PUBMED   17303383
REFERENCE   6  (bases 1 to 2400)
  AUTHORS   Jacinto,E., Facchinetti,V., Liu,D., Soto,N., Wei,S., Jung,S.Y.,
            Huang,Q., Qin,J. and Su,B.
  TITLE     SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt
            phosphorylation and substrate specificity
  JOURNAL   Cell 127 (1), 125-137 (2006)
   PUBMED   16962653
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079073.1.
            
            On Feb 11, 2005 this sequence version replaced XM_216040.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079073.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132272
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2400
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p11"
     gene            1..2400
                     /gene="Mapkap1"
                     /note="MAPK associated protein 1"
                     /db_xref="GeneID:296648"
                     /db_xref="RGD:1305363"
     exon            1..373
                     /gene="Mapkap1"
                     /inference="alignment:Splign:2.1.0"
     exon            374..701
                     /gene="Mapkap1"
                     /inference="alignment:Splign:2.1.0"
     CDS             443..2011
                     /gene="Mapkap1"
                     /note="TORC2 subunit MAPKAP1; SAPK-interacting protein 1;
                     stress-activated map kinase-interacting protein 1;
                     mitogen-activated protein kinase 2-associated protein 1;
                     mitogen-activated protein kinase associated protein 1;
                     target of rapamycin complex 2 subunit MAPKAP1-like"
                     /codon_start=1
                     /product="target of rapamycin complex 2 subunit MAPKAP1"
                     /protein_id="NP_001011964.1"
                     /db_xref="GeneID:296648"
                     /db_xref="RGD:1305363"
                     /translation="MAFLDNPTIILAHIRQSHVTSDDTGMCEMVLIDHDVDLEKTHPP
                     SVPGDSGSEVQGSSGETQGYIYAQSVDITSSWDFGIRRRSNTAQRLERLRKERQNQIK
                     CKNIQWKERNSKQSAQELKSLFEKKSLKEKPPSSGKQSILSVRLEQCPLQLNNPFNEY
                     SKFDGKGHVGTTATKKIDVYLPLHSSQDRLLPMTVVTMASARVQDLIGLICWQYTSEG
                     REPKLNDNVSAYCLHIAEDDGEVDTDFPPLDSNEPIHKFGFSTLALVEKYSSPGLTSK
                     ESLFVRINAAHGFSLIQVDNTKVTMKEILLKALKRRKGSQKISGPQYRLEKQSEPNIG
                     VDLESTLESQNAWEFCLVRENSSRADGVFEEDSQIDIATVQDMLSSHHYKSFKVSMIH
                     RLRFTTDVQLGISGDKVEIDPVTNQKASTKFWIKQKPISIDCDLLCACDLAEEKSPSH
                     AVFKLTYLSSHDYKHLYFESDAATVSEIVLKVNYILESRASTARADYFAQKQRKLNRR
                     TSFSFQKEKKSGQQ"
     exon            702..791
                     /gene="Mapkap1"
                     /inference="alignment:Splign:2.1.0"
     exon            792..940
                     /gene="Mapkap1"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1113
                     /gene="Mapkap1"
                     /inference="alignment:Splign:2.1.0"
     exon            1114..1290
                     /gene="Mapkap1"
                     /inference="alignment:Splign:2.1.0"
     exon            1291..1400
                     /gene="Mapkap1"
                     /inference="alignment:Splign:2.1.0"
     exon            1401..1508
                     /gene="Mapkap1"
                     /inference="alignment:Splign:2.1.0"
     exon            1509..1649
                     /gene="Mapkap1"
                     /inference="alignment:Splign:2.1.0"
     exon            1650..1787
                     /gene="Mapkap1"
                     /inference="alignment:Splign:2.1.0"
     exon            1788..1885
                     /gene="Mapkap1"
                     /inference="alignment:Splign:2.1.0"
     exon            1886..2371
                     /gene="Mapkap1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagggttgct gttgccggcc ggcagctgcg gggagcggcg gggtcatgag ggcgagcccg
       61 gggcgccagg gccgagccgg ccggtaggat tgcgggtccc cgaggacttc gtgggcgcag
      121 ggttcggtgt aggggccggg aggcgtaggg gagtcaggac ctccctcagg gacgtgtcct
      181 gggcgaggcg gcctgtagtg ctggaagcag cttcaggtaa aggttgcccc agccgtcgcc
      241 ccctcgcccg cggaaccctc cgacccctca gcaccccgct gtcctcgctg tccagcggcg
      301 cccgttgggg ccgtgctcgg tggcctggga gcatccgttt cctggcagcc tgacagctgg
      361 gtgtgtgact taggtaggtg agcctgtgaa acagtatgaa gaggagaaaa tagcctttta
      421 aagagactgg cccacagaaa ggatggcctt cttggacaat ccaactatca ttctagctca
      481 tattcgacag tcacatgtga ccagtgatga cacgggaatg tgtgagatgg ttctcattga
      541 tcatgacgtt gacctagaga agactcatcc tccgtcagtg cctggagaca gtgggtcaga
      601 agttcaggga agcagtggtg agacgcaggg ctacatatac gcccagtctg ttgatattac
      661 ctcgagctgg gactttggta ttagaagacg ctcaaacaca gctcaaagat tagaacgact
      721 ccgcaaagag agacaaaacc agatcaaatg caaaaatatt cagtggaaag aaagaaattc
      781 taaacaatca gcccaggagt taaagtcact gtttgaaaaa aaatccctca aagagaaacc
      841 tccaagttcg ggcaagcagt ccatattgtc tgtgcgcctg gaacagtgcc ctctgcagct
      901 gaataacccc tttaatgagt actccaagtt tgatggcaag ggtcatgtgg gtacaactgc
      961 aacgaagaag atcgacgtct acctccccct gcactcaagc caggacagac tgctgccaat
     1021 gactgtggtg accatggcca gcgccagggt gcaggacctc atcgggctca tctgttggca
     1081 gtacacgagt gaaggacggg agccaaagct caatgacaac gtcagtgcct actgcctgca
     1141 tattgctgag gatgatgggg aggtggacac ggatttccca ccgctggatt ccaatgaacc
     1201 cattcataag tttggcttca gtactttggc cctggttgaa aagtactctt cccctggtct
     1261 gacctccaaa gagtcgctct ttgttcgaat aaatgctgcc catgggttct ccctcatcca
     1321 ggtggacaac acgaaggtca ccatgaagga gatcttactc aaggcactga aacgaagaaa
     1381 agggtcccag aaaatttcag gccctcagta ccgcctggag aagcagagcg agcctaacat
     1441 cggtgtggac ctggagagca cgctggagag ccagaatgcc tgggagttct gcctggttcg
     1501 agagaacagt tcaagggcag acggagtttt cgaggaggat tcacaaattg acattgctac
     1561 agtgcaggat atgcttagca gccaccatta taagtcattc aaagtcagca tgatccacag
     1621 actgcggttc acaactgacg tgcagttagg tatctctgga gacaaagtgg agatagaccc
     1681 tgttacgaat cagaaagcca gcactaagtt ttggattaag cagaagccca tctcaatcga
     1741 ttgtgacctg ctctgtgcct gtgaccttgc cgaggagaag agccccagtc acgcggtctt
     1801 taagctcacg tatctaagca gtcacgacta taagcatctc tacttcgagt ccgacgcagc
     1861 taccgtcagt gaaatcgtgc tcaaggttaa ctacatcctg gagtcacgag caagcactgc
     1921 ccgtgctgac tattttgctc aaaaacaaag aaaactgaac aggcggacga gcttcagctt
     1981 ccagaaggag aagaaatcag ggcagcagtg acactggcct ccagtctggt gccacaaccc
     2041 ggactgcctg caaggccagg tggaccagag tcctccggca tcctatagag ccaagacccg
     2101 cagacacagg ctgctgggcg cgaggggaag gtttagaggt aggggtacca ttggactgaa
     2161 gcttggccat ggttctaagt agcaatgtcc aggggccagc cccctcctgg agggcggaga
     2221 gctactcagc cgtgctcact gtctggcagc cccaagggtg tacatagata gccatgccag
     2281 acatctcctt gcaacttgat caaatttctt aaacaaagaa caaagtgtac atttcttttt
     2341 ttccttttaa taaactcttt atcatggttg gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
