LOCUS       XM_039091284            5727 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus mitogen-activated protein kinase
            kinase kinase 19 (Map3k19), mRNA.
ACCESSION   XM_039091284
VERSION     XM_039091284.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051348.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039091284.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5727
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5727
                     /gene="Map3k19"
                     /note="mitogen-activated protein kinase kinase kinase 19;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 4 long SRA reads, 4 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 23 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:289001"
                     /db_xref="RGD:1566400"
     CDS             702..5243
                     /gene="Map3k19"
                     /codon_start=1
                     /product="mitogen-activated protein kinase kinase kinase
                     19"
                     /protein_id="XP_038947212.1"
                     /db_xref="GeneID:289001"
                     /db_xref="RGD:1566400"
                     /translation="MNKNKLIHDFLEVVSRGDVECICSHIPEVHSVLGNLDFQHPQTG
                     NTPLITAAEENLSEVVEILLERGADITLCNYSNQTALHVANGDIQRQLLAGRGIQAPQ
                     MQLLRSSWQGDLERLRHLLACEEFLDINFPNSHGLTPLMLAVRDVDLFESLDVSTVYR
                     PAEVLAELLRHHADPKLCDFSGKSAMHYVSQINSWRKQQLLVILTDSMPKPERHAESL
                     LDICHEAGSTPMDMTVSKTENITLQSISSSSSEDFALDDDFSPSILAGEGTAPRGEGW
                     PRRTEGVEILVTMFPPDSPQEASQEDLTESSQVTSERPEWGPGHPVSPAKEVEMVGLT
                     SRMLTTQPSLLKTEGGSQELCGADVALSPPRPCLDPSTAIAAVREEAPHVLKVQPRKS
                     DKFPTSDMRYSSRRTELPLPPPSLLPMRSSVFNMEKSPKFPRHGERKVPSLSLSVPKL
                     LEPLSQPLSQSAEFSSAKNQQEVTWEGPPEHTLRGSDWAIWSRNLCSFRKSRKQRGVA
                     ESWRSQETKGGDKTETSGFEEGPFLFSCGSVKEDTAPIERERDSGCHISEISGREDSQ
                     YLLSGEKESWTDRAVEKDLEVEHPFLSELLEASNTKITLAEEKEIGNEKVPDSESNSV
                     HRAGTVQPHAVLEELSVPKNIPRMNSDGPITGLLEGHGDTEENRKLPIEEETNPEMNG
                     AVPLVHITFPGEGTPKGPARAKPNLQRRKHPVQSSGSPNILARQEHGKLQTNTHRTKA
                     RNRPPPNLMVSIQASIKPNVRKNSIKTQVFPALEFMDHRPHPPSKFQRRAPVTEKKSM
                     CQTQKPKKQAFPHICKNAGIKKPGVVLSVETTDPRLHFLDLKYSDMFKEINSASNGPG
                     IYEMFGTPVYSHIREAERHEHRHYHEICAAPSGRSVGNKCQPSQSDRCANSRARLLQK
                     RPHVKPPKPSLGLKQKHRGLISKDKGCKGMGGHVEDSVSEPGWQTRPSANDSLSSKDE
                     AQLTHLTLIPETSPEQRETPPLSDLSIVEEIFTEECADEEGILHNDSLTQSLGDLKAL
                     EGLHPQTPLVPSEDSWAVLSEKHSGKHVSPGKHDVGPLDKINADQMFTGYLEFDSLSD
                     KSKTRVSFSRYSFQEKPESAPSPTEQPWAHSLDQDSLEDDSTTYQRFGKVSQGILDPG
                     KNEELTDELLGCLVEELLAIDEKDNNSCRIMTNEADTRDLNLVFGRRGNTIEGLDRET
                     TDVKLQRCINGFQIYDEENFLTSYEERTLSDNSLKHEEAIFWTKGEILGRGAYGTVYC
                     GLTSLGQLIAVKQVALDSTDKLATEKEYRKLQEEVDLLKALKHVNIVAYLGTCLEENT
                     LSIFMEFVPGGSISSIINRFGPLPETVFCKYTRQILQGVAYLHENCVVHRDIKGNNVM
                     LMPTGIIKLIDFGCAKRLAWAGLNGTHSDMLKSMRGTPYWMAPEVINESGYGRKSDIW
                     SIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDRFSEPAADFVRLCLTRDQ
                     HERPSALQLLTHAFMLRSQ"
ORIGIN      
        1 tttccctttc tcagcatggg acttccagtt tctggtggtc tagtgcttca gtagtgtgag
       61 agtcaaagga aggggtacca gtgtctcctt agaatgtctt cattcatacc tgtacggttt
      121 atactgtccc tctggcctaa cttggatttg aaaagggact ttcagcacct agcagggatt
      181 acagaggcat ggctcctctg gagaacatct cattaagtag agtagaaaag gcagtgggtc
      241 atccacggat gtgcacaggg gctcagcttc tttaaccact ccaacagcag cttacacgca
      301 tgcacaacac ttgttttcct tcttccgtaa gactgtcctg ctcttaattc tccaagctaa
      361 acactctgcg gctggttgcc tgggtgacag cctgtgtaaa ctaagcaagt ctccttgcac
      421 tgagccaaag ggtttgtgca cccagaacca gctttaaata ctttaaaaaa gaaaaaataa
      481 agtgtttgaa cttcacaaca ctggaacgga accaaacacg aggttctgaa tctatgctgc
      541 ttttaaatgg aaacgtggct aaagtgagcg ttgatagctg gtttggaaat cagagccatg
      601 aagtaggatg atttaggctg ttactcggct gggtgctcct tcatctgggt cccaactccc
      661 tcagcaaagc tgactctagg aaattatatg gaaccagcaa gatgaacaaa aacaaactga
      721 ttcatgattt ccttgaagtg gtttcaaggg gtgatgtgga atgcatttgt agccatattc
      781 cagaagtcca ctcagtcctt ggaaaccttg actttcagca cccacagact ggaaacacgc
      841 ctctcattac agctgcggaa gaaaatctat cagaggttgt tgagattctt ctggaaaggg
      901 gcgcagacat cacactttgc aattacagta accaaactgc gctccatgtg gctaatggtg
      961 acatccagag acagctcttg gcaggcaggg ggattcaggc tccccaaatg cagctcctac
     1021 gaagttcgtg gcaaggtgat ctggaacgac ttcgacattt gctggcatgt gaagagttcc
     1081 tggatataaa ctttcccaac tcgcatggtc tgacccctct gatgctggct gtgagagatg
     1141 tggacctatt tgaaagtctg gatgtatcaa cagtctacag acccgccgaa gttctagccg
     1201 agctcctcag gcaccacgca gaccctaagc tgtgtgattt cagtggcaag tcagccatgc
     1261 attatgtgtc ccaaatcaac agctggagga agcaacagtt actggtcatc ctgacggatt
     1321 ctatgcccaa accagaaaga catgccgagt cactgcttga catctgtcac gaggcaggct
     1381 ctactccaat ggatatgaca gtttccaaaa cggaaaatat caccttgcag agcatcagca
     1441 gcagcagcag cgaggacttt gcccttgacg atgacttcag tccatccata ttggctgggg
     1501 aaggaacagc tccccggggt gaaggctggc cacgaaggac agaaggtgtt gagattcttg
     1561 tgacgatgtt tccaccagat tctccccaag aagcaagcca ggaagatttg acagaaagca
     1621 gtcaggtgac ttcagagcgt ccggagtggg gaccagggca tcctgtctct ccagcgaagg
     1681 aagtggagat ggtgggcctc acgtcaagga tgttaactac acagccttca cttctgaaga
     1741 cagaaggggg atctcaggag ctctgtgggg cagatgtggc tctctcacca ccaaggcctt
     1801 gcttagaccc aagcacggct atagctgcag tcagggagga ggctcctcat gttctgaaag
     1861 tgcagccaag aaaatccgac aagtttccta cctctgacat gagatacagt agccgaagaa
     1921 ctgagctccc tctgccacct ccatccctct tgcccatgag atcgtctgtc ttcaatatgg
     1981 aaaaaagccc caagttccca agacacgggg agagaaaggt ccccagcctc agcctgtctg
     2041 tgcctaagct cctggagccc cttagccaac ctcttagcca atctgctgag tttagttcag
     2101 ctaagaacca acaagaagtc acatgggaag gacccccaga acacaccctc aggggttctg
     2161 actgggctat ctggtctaga aatttgtgct ctttccggaa gagcagaaaa cagaggggag
     2221 tagcagaaag ttggcgatcc caggaaacga aaggtgggga caaaactgaa acctctggct
     2281 tcgaagaagg gccctttttg ttctcctgtg ggagtgtcaa ggaagacact gctcctatag
     2341 agagggaaag ggatagtggc tgccacatta gtgaaatcag cgggagagag gactcgcaat
     2401 atcttttatc aggagaaaaa gagagttgga cagatagagc ggttgagaaa gatttggagg
     2461 ttgagcaccc ctttctcagc gagctcctgg aagcctcgaa tacaaaaata accctagcag
     2521 aggagaaaga gatcggaaat gagaaagttc ccgattccga aagcaattcg gtacaccggg
     2581 ctggaacagt gcagccacac gcagtgttag aagagcttag tgttcctaag aacataccca
     2641 ggatgaactc tgatggcccc atcacagggc tcctagaagg tcatggagac acagaagaga
     2701 acagaaaact gccgatcgag gaagaaacaa acccagaaat gaatggggca gtgccacttg
     2761 ttcacatcac attccctgga gaagggacac ccaagggacc tgctagagct aaaccaaacc
     2821 tccaaaggag aaagcacccg gtgcagagca gcggtagccc caacatactc gctcgacaag
     2881 aacacggcaa actccagaca aatactcaca ggaccaaggc cagaaacaga ccacctccta
     2941 atctcatggt ttccatccaa gcatccatta aacctaacgt gcgtaaaaac agcatcaaaa
     3001 ctcaagtttt ccctgctttg gaatttatgg accacagacc tcatccgcca tccaagtttc
     3061 aaaggagagc acccgtgaca gaaaagaagt caatgtgtca gacccagaaa cctaagaagc
     3121 aagcatttcc tcacatctgt aaaaatgcag gcataaaaaa gccaggcgtt gtcctctctg
     3181 ttgaaacaac cgatccaaga ttgcacttcc tggacttgaa gtacagtgac atgttcaaag
     3241 agatcaattc agcctccaac ggaccaggca tctatgagat gtttggaacc cctgtttata
     3301 gtcacatccg agaggcagaa aggcacgaac acagacatta ccatgagata tgtgcagctc
     3361 catcaggacg aagtgttggt aataagtgtc agccttccca aagtgacaga tgtgccaaca
     3421 gcagagcaag acttcttcag aagagacctc acgttaaacc ccccaagcct tcactcgggc
     3481 tcaagcaaaa gcacagaggg ttaatttcta aagataaggg ttgcaagggt atggggggcc
     3541 acgtagagga tagcgtttca gaaccaggtt ggcagacgag accttcagca aatgactctc
     3601 tgtcttccaa agatgaggct caactcacgc acttgaccct gatccctgag acgtctcctg
     3661 aacagagaga aacccctcct ctctcagatc tatccattgt tgaggaaatc ttcacggagg
     3721 agtgtgcaga tgaagaaggc attcttcata atgacagtct tacccaaagc cttggagatc
     3781 tgaaagcact tgaagggctg cacccccaga ccccgctcgt tccttcagaa gacagctggg
     3841 ctgtgctcag cgagaagcat tcaggcaagc atgtgtcacc aggaaaacat gatgtaggac
     3901 ctcttgacaa aataaatgct gaccagatgt tcacgggtta cctggagttc gatagccttt
     3961 cggataagtc taaaacaagg gtgagctttt ccaggtactc tttccaggag aagccagaaa
     4021 gtgcaccttc ccctacagaa caaccctggg cacattcctt ggatcaggat agcttagaag
     4081 atgactccac cacataccaa aggtttggaa aggtttccca gggaatctta gacccaggaa
     4141 agaatgaaga attgacagac gagttgctgg gttgtctggt cgaagaactg ttagcaattg
     4201 acgagaaaga taacaactct tgccgaataa tgacaaatga ggccgacacc cgggacctga
     4261 atcttgtctt cggcaggaga ggcaacacca tcgaaggact ggacagagag acaacagatg
     4321 tcaaactaca gaggtgtatt aatggattcc agatatacga tgaggaaaac tttcttacct
     4381 catatgaaga gaggacactt tcggacaaca gtttaaaaca cgaagaggct atattctgga
     4441 ccaagggtga gatccttggg agaggagcct atggcacagt atattgtggg ctcaccagcc
     4501 tggggcagct gatcgctgta aagcaggtgg ccttggattc gaccgacaaa ctggctacgg
     4561 agaaagaata ccggaaactg caggaggaag tggatttgct gaaggcgctg aagcacgtaa
     4621 acatagtggc ttatctaggg acgtgcctgg aggagaacac tctgagcatc ttcatggaat
     4681 tcgtccctgg tggttccatc tctagcatca taaaccgctt tgggccactg cctgagaccg
     4741 tgttctgtaa atacacaaga cagatcctgc agggtgttgc ttatctccat gagaactgtg
     4801 tggtgcaccg agatatcaaa ggaaacaatg tcatgctcat gccaactggg ataataaagc
     4861 tgatcgactt tggctgcgcc aagcgtttgg cctgggcagg cttaaatggt acccacagtg
     4921 acatgctcaa gtctatgcgt gggactccgt actggatggc ccccgaggtc atcaacgagt
     4981 ccggctacgg aaggaaatca gatatatgga gcattggctg caccgtgttt gagatggcca
     5041 cggggaagcc ccctctggct tccatggatc ggatggcagc catgttttac attggagccc
     5101 acagaggcct aatgcctccc ctacctgacc ggttctcaga accagctgcg gactttgtgc
     5161 gtttgtgcct gaccagggac cagcacgaga gaccttctgc tctccagctc ctgacgcacg
     5221 ccttcatgct gagaagccag tgagcaaacg tgcaccgact tccggcttta aaccctcaat
     5281 cctctgcttt gctgtgggga atgatggtta agggacttat tttcctaatg taaatccgac
     5341 ctaaatggtg aatcccattt aaccagatcc tgcagcatta ttggaaagtt ttagttaacg
     5401 ccgaccttaa ggttcaggta cgactgcctg tatgcgtgag aacaatttca taatattaaa
     5461 aaccccgttc cagtgttaca gttttgattg ctcaaaaact atctctactg attaacagaa
     5521 tatttttttc ttttgagaca ggatttcatt acataaccct ggctatcctg gaacttgcta
     5581 tgtagaccag gttagctttg aactcacgga gatctgcctg cctctacctc ggagtgctga
     5641 atattaaagg tgtgagccac cacacccagc ttagttcttt taagtttaaa ataaattgca
     5701 cacattttgc ctgatagcat gcttatt
//
