LOCUS       XM_039100568            4588 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus mitogen-activated protein kinase
            kinase kinase 15 (Map3k15), mRNA.
ACCESSION   XM_039100568
VERSION     XM_039100568.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051356.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039100568.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4588
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4588
                     /gene="Map3k15"
                     /note="mitogen-activated protein kinase kinase kinase 15;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 10 ESTs, 6 Proteins, and 96% coverage of
                     the annotated genomic feature by RNAseq alignments"
                     /db_xref="GeneID:501558"
                     /db_xref="RGD:1560603"
     CDS             248..4231
                     /gene="Map3k15"
                     /codon_start=1
                     /product="mitogen-activated protein kinase kinase kinase
                     15"
                     /protein_id="XP_038956496.1"
                     /db_xref="GeneID:501558"
                     /db_xref="RGD:1560603"
                     /translation="MEGSGGGGLAPAEAPEEAGESPQGRLPPGPEGAAGPAEPESAGD
                     AAGGETEGGRGPRRALRAVYVRSESSQGAAAGGGPEAGALKCLLRACEAEGAHLTSVP
                     FGELDFGETAVLDAFYDADVAIVDMSDISRQPSLFYHLGVRESFDMANNVILYYDTDA
                     DTALSLKDMVTQKNIASSGNYYFIPYTVTPCADYFCCESDAQRRASEYMQPNWDTILG
                     PLCMPLVDRFTTLLKDIRVTSCAYYKETLLNDIRKAREKYQGDELAKELTRIKFRMDN
                     IEVLTSDIIINLLLSYRDIQDYDAMVKLVETLKMLPTCDLADQHNIKFHYAFALNRRN
                     STGDREKALQVMLQVLRSCDHPAPDMFCLCGRIYKDIFLDSGCEEDASRDSAIEWYRK
                     GFELQSSLYSGINLAVLLIVSGQQFETSMELRKIGVRLNSLLGRKGSLEKMNNYWDVG
                     QFFTVSMLASDIGKAVQAAERLFKLKPPVWYLRSLVQNLLLIQRFKKPITEHSPRQER
                     LNFWLDIIFEATNEVTNGLRFPVLVIEPTKIYQPAYVSINNEAEERTVSLWHVSPTEM
                     KQIHEWNFTASSIKGISLSKFDERCCFLYVHDNSDDFQIYFSTEEQCNRFCSLVKEML
                     NNGVGSTVELEGEADGDTLEYEYDHDVNGERVVLGKGSYGVVYAGRDLSNQVRIAIKE
                     IPERDIRYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIKIFMEQVPGGSLSALLRS
                     KWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKR
                     LAGINPCTETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSRPPFHELGE
                     PQAAMFKVGMFKIHPEIPEALSAEARAFILSCFEPDPQKRVTAADLLQEGFLRQVNKG
                     KKNRIAFKPSEGVRSGTGTLALPSSGELMGSSSSEHGSISPDSDAQPDAFFEKVQVPK
                     PQLSHLLSVPDESSALDDRSTALPPEERDPGLFLLRKDSERRAILYRILWEEQNQVAS
                     NLQECVVQSSEELLLSVGHIKQIIGILRDFIRSPEHRVMAATISKLKVDLDFDSSSIN
                     QIHLILFGFQDAVNRILRNHLIRPHWMFAMDNIIRRAVQAAVAILIPELQAHFEPASE
                     TEGVDKDTEMERDYPLVDLLSQEVHVTTRGTRHGSVAIQEGQPHQQDPSLQLSKLRQE
                     TNRLWEHLVQKEREYQNLLRLILEQKTQELYHLQLQYKCNGGTENPPPHDGLGTNREL
                     IDWLQLQGVDANTIEKIVEEDYTLSDILNDITKEDLRCLRLRGGVLCRLWHAVSQHRR
                     QMQESSQ"
ORIGIN      
        1 ccgagccccc gcctctttct cgcgggcttt caaagggcgc tcggggcaag ccggccctga
       61 gcttctctcg gcggcctctg gagagcccgt ggtcacctgc ctgcagcgtc ctctccgccc
      121 acccccagct ccctgcagct gccgtccgtc cttacgtccg tccgtccgtc cgtctgtcgc
      181 ctctgcagca ggtgcctcgg ggaagagcac ctcgccttcg aagtcgccag ccccgcaggc
      241 cagtcacatg gagggcagcg gcggaggcgg gctggcccct gctgaggcgc ccgaggaggc
      301 aggcgagtcg ccccagggca ggctgcctcc ggggcccgag ggcgcggcgg ggccggcgga
      361 gcccgagagt gcgggggacg ctgccggcgg cgagactgag ggcgggcgcg ggccgcgccg
      421 ggctctgcgg gctgtatacg tgcgcagcga aagttcgcag ggggcggcag ccggcggcgg
      481 ccccgaggcc ggggcactca agtgcctgct tcgggcctgc gaagccgagg gcgcccacct
      541 cacctccgta ccctttgggg agctcgactt cggggagacc gccgtgctcg atgccttcta
      601 tgatgcagat gttgccattg tggacatgag tgatatctcc agacagcctt cccttttcta
      661 tcatcttgga gtccgagaga gttttgacat ggctaataat gtaattctgt actacgatac
      721 tgatgctgac actgctctgt cgttgaagga tatggtcact caaaaaaaca tagcatctag
      781 cggaaattat tatttcatcc cctacactgt gacaccgtgt gctgattatt tttgctgtga
      841 gagtgatgcc caaaggagag cctcggagta catgcagcct aactgggaca ccatcctagg
      901 cccactgtgt atgcccctgg tggacaggtt cactaccctc cttaaggata ttcgtgtgac
      961 ttcatgtgct tattataaag aaacattgtt aaatgacatc cggaaagcca gagagaaata
     1021 ccaaggtgat gaactggcaa aagagctgac tcggatcaaa ttccgcatgg acaacattga
     1081 ggttctgaca tcagacatca tcattaactt acttctgtcc taccgtgata tccaggacta
     1141 tgatgcaatg gtcaaacttg tagaaacatt gaagatgctg cctacatgtg acttggctga
     1201 tcagcacaac attaaatttc actacgcatt tgcactgaat aggaggaaca gcacaggtga
     1261 ccgtgaaaag gctctgcagg tcatgctcca agttctgcga agctgtgacc accctgctcc
     1321 tgacatgttt tgcctgtgtg ggaggatcta caaggacatc ttcctggatt cgggttgtga
     1381 agaggatgca agcagagaca gtgccattga gtggtatcgc aaagggtttg aactccagtc
     1441 atccctttat tcgggaatta accttgcagt tttgctgata gtttctggac aacagtttga
     1501 aacttcgatg gaactaagga aaataggtgt ccggctgaac agtttattgg gaagaaaagg
     1561 gagcctggag aaaatgaaca attactggga tgtaggtcag ttcttcaccg tcagcatgct
     1621 ggcaagtgat attgggaagg ctgtacaggc agcagagagg ttgttcaaac tgaaaccccc
     1681 agtctggtac ctgcggtcat tagttcagaa cttgctgtta attcaacgct tcaagaaacc
     1741 cattacagaa cattcaccca ggcaggaacg gcttaacttc tggttagata tcatttttga
     1801 agcaacaaac gaagttacta atggactcag atttccagtt ctggtaatag agcccaccaa
     1861 aatctaccag cctgcttatg tttctatcaa caatgaagct gaagaaagaa ctgtttcttt
     1921 atggcatgtc tcacccacag aaatgaaaca aatccatgaa tggaatttta cagcctcttc
     1981 tattaaagga atcagcctat ccaagtttga tgaacggtgc tgttttcttt atgtccatga
     2041 taattctgat gactttcaaa tctacttttc caccgaagaa cagtgcaata ggttttgctc
     2101 tttggtcaaa gagatgctga acaatggagt gggcagtaca gtggagttgg agggagaggc
     2161 ggatggagac accttagagt atgagtatga ccatgatgtg aatggggaga gagttgtctt
     2221 ggggaaaggc tcctatgggg ttgtgtatgc cggccgtgat ctgagtaatc aagtacgaat
     2281 agccatcaag gaaatcccag agagagatat cagatactct cagcctctgc atgaagaaat
     2341 agctctacac aagtatctca agcatcgaaa catcgtccag tatcttggct ctgtctcaga
     2401 gaatggctac attaagatat ttatggagca ggtgcctgga ggaagccttt ctgctctctt
     2461 gcgatctaaa tggggaccca tgaaggaacc tactatcaag ttttatacca aacagatcct
     2521 ggaaggcctg aagtatctcc acgaaaacca gatagtgcac agggacataa agggtgataa
     2581 tgttctggtg aatacctata gtggagtggt aaaaatctct gattttggaa cctctaaacg
     2641 cctcgcagga attaacccat gcaccgagac atttacaggg actctgcagt acatggcacc
     2701 tgagattatt gatcaagggc ctcgagggta tggtgctcca gctgatatct ggtccttggg
     2761 ctgcaccatc attgagatgg caaccagcag gcctccattc catgagcttg gcgagccaca
     2821 agcagccatg tttaaggtag ggatgtttaa gatccaccct gaaattccag aggccctgtc
     2881 agctgaagcc agagccttca tcttgtcttg ttttgagcct gaccctcaga aacgtgtcac
     2941 tgctgctgac cttctccaag aagggttctt aaggcaggtg aacaaaggca aaaagaaccg
     3001 aattgctttc aagccttcag agggtgttcg gagtggcact ggtactctgg ctctgccttc
     3061 atctggggag cttatgggca gcagcagcag cgagcatggc tcaatctccc cagactcgga
     3121 tgcccaacct gacgcattct ttgagaaggt ccaggtgccc aaacctcagc tcagccacct
     3181 tctcagtgtc ccagatgaaa gctcagcctt agatgaccga agcacagccc tacccccaga
     3241 ggaaagagac cctggcctct ttctgctgcg caaggacagt gaacgcagag ccatcctgta
     3301 cagaatcctt tgggaggagc agaaccaagt ggcctccaac ttgcaggagt gcgtggtcca
     3361 gagttcagaa gagttgcttc tctcagttgg ccacatcaaa cagataattg gaatcctaag
     3421 ggacttcatc cgctccccag agcacagggt gatggcagcc acaatatcaa aactgaaggt
     3481 ggacctggac tttgacagtt catccatcaa ccagattcac ctgattctat ttggattcca
     3541 agatgccgtc aatagaattt tgagaaacca cttaattagg ccccactgga tgtttgcaat
     3601 ggacaacatc attcgcagag ctgtgcaggc tgcagttgcc attctcattc cagagctcca
     3661 agcccacttt gagcctgctt ctgagactga aggggtagac aaggacacag aaatggaaag
     3721 ggactatccc ctagtagacc tcctcagcca agaagtacat gtgacaacca gaggcaccag
     3781 acatggctca gtggctatcc aggagggcca gccccaccag caggacccaa gtctccaact
     3841 gagcaagctc aggcaagaga ccaacagact ttgggaacac ttagttcaaa aagagagaga
     3901 gtaccagaat cttcttcggt taattctaga acaaaaaact caagaattat atcaccttca
     3961 gttacaatac aaatgcaatg gtggaacaga gaacccacca ccccatgacg gactgggaac
     4021 caacagagag cttatagact ggttgcagct acaaggagtg gatgcaaata caatagaaaa
     4081 gattgttgaa gaagattaca cactttctga tattctcaat gatatcacta aggaagacct
     4141 aaggtgcctc agactacgtg gtggtgtcct ctgtaggctc tggcatgcag tctcccagca
     4201 cagaagacaa atgcaggagt cctcacaata agccaagctg gggagaatga gcaaaaagta
     4261 ccctacacct gctcacgatt aaagcttctg ttagtgcaca cacaaatcct gcgtttacac
     4321 agaaagaccc ttgttcgttt cattcaagca catgtgattt agagcatact tgtttataaa
     4381 ccggattgta agtaatgtct ctcctgacct agtatttaaa atgtcagcat accttatagc
     4441 agttgctgga aagataaagc ctaagtattt tataaaccag tgtaattact taaatgtgaa
     4501 aagttaaaaa gtgtgccttg gaatgggagt acaattttgt gtttgttaaa tgtctaaatg
     4561 gagaaaatta aattatttta cctttgaa
//
