LOCUS       NM_019316               1921 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus MAF bZIP transcription factor B (Mafb), mRNA.
ACCESSION   NM_019316
VERSION     NM_019316.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1921)
  AUTHORS   Park,J.G., Tischfield,M.A., Nugent,A.A., Cheng,L., Di Gioia,S.A.,
            Chan,W.M., Maconachie,G., Bosley,T.M., Summers,C.G., Hunter,D.G.,
            Robson,C.D., Gottlob,I. and Engle,E.C.
  TITLE     Loss of MAFB Function in Humans and Mice Causes Duane Syndrome,
            Aberrant Extraocular Muscle Innervation, and Inner-Ear Defects
  JOURNAL   Am J Hum Genet 98 (6), 1220-1227 (2016)
   PUBMED   27181683
REFERENCE   2  (bases 1 to 1921)
  AUTHORS   Nishimura,W., Ishibashi,N., Eto,K., Funahashi,N., Udagawa,H.,
            Miki,H., Oe,S., Noda,Y. and Yasuda,K.
  TITLE     Demethylation of the MafB promoter in a compromised beta-cell model
  JOURNAL   J Mol Endocrinol 55 (1), 31-40 (2015)
   PUBMED   26108485
  REMARK    GeneRIF: The chronic culture of the rat beta-cell line resulted in
            partial DNA demethylation of the MafB promoter.
REFERENCE   3  (bases 1 to 1921)
  AUTHORS   Zhang,Y. and Ross,A.C.
  TITLE     Retinoic acid and the transcription factor MafB act together and
            differentially to regulate aggrecan and matrix metalloproteinase
            gene expression in neonatal chondrocytes
  JOURNAL   J Cell Biochem 114 (2), 471-479 (2013)
   PUBMED   22961837
  REMARK    GeneRIF: These results support a role for MafB as a regulator of
            chondrocyte gene expression and matrix formation via control of
            aggrecan, MMP3 and MMP13 expression, and indicate an important role
            for RA in the regulation of MafB
REFERENCE   4  (bases 1 to 1921)
  AUTHORS   Smink,J.J., Begay,V., Schoenmaker,T., Sterneck,E., de Vries,T.J.
            and Leutz,A.
  TITLE     Transcription factor C/EBPbeta isoform ratio regulates
            osteoclastogenesis through MafB
  JOURNAL   EMBO J 28 (12), 1769-1781 (2009)
   PUBMED   19440205
REFERENCE   5  (bases 1 to 1921)
  AUTHORS   Sultana,D.A., Tomita,S., Hamada,M., Iwanaga,Y., Kitahama,Y.,
            Khang,N.V., Hirai,S., Ohigashi,I., Nitta,S., Amagai,T.,
            Takahashi,S. and Takahama,Y.
  TITLE     Gene expression profile of the third pharyngeal pouch reveals role
            of mesenchymal MafB in embryonic thymus development
  JOURNAL   Blood 113 (13), 2976-2987 (2009)
   PUBMED   19164599
REFERENCE   6  (bases 1 to 1921)
  AUTHORS   Li,R., Pei,H., Watson,D.K. and Papas,T.S.
  TITLE     EAP1/Daxx interacts with ETS1 and represses transcriptional
            activation of ETS1 target genes
  JOURNAL   Oncogene 19 (6), 745-753 (2000)
   PUBMED   10698492
REFERENCE   7  (bases 1 to 1921)
  AUTHORS   Matsushima-Hibiya,Y., Nishi,S. and Sakai,M.
  TITLE     Rat maf-related factors: the specificities of DNA binding and
            heterodimer formation
  JOURNAL   Biochem Biophys Res Commun 245 (2), 412-418 (1998)
   PUBMED   9571165
REFERENCE   8  (bases 1 to 1921)
  AUTHORS   Sakai,M., Imaki,J., Yoshida,K., Ogata,A., Matsushima-Hibaya,Y.,
            Kuboki,Y., Nishizawa,M. and Nishi,S.
  TITLE     Rat maf related genes: specific expression in chondrocytes, lens
            and spinal cord
  JOURNAL   Oncogene 14 (6), 745-750 (1997)
   PUBMED   9038383
REFERENCE   9  (bases 1 to 1921)
  AUTHORS   Sieweke,M.H., Tekotte,H., Frampton,J. and Graf,T.
  TITLE     MafB is an interaction partner and repressor of Ets-1 that inhibits
            erythroid differentiation
  JOURNAL   Cell 85 (1), 49-60 (1996)
   PUBMED   8620536
REFERENCE   10 (bases 1 to 1921)
  AUTHORS   McKay,I.J., Muchamore,I., Krumlauf,R., Maden,M., Lumsden,A. and
            Lewis,J.
  TITLE     The kreisler mouse: a hindbrain segmentation mutant that lacks two
            rhombomeres
  JOURNAL   Development 120 (8), 2199-2211 (1994)
   PUBMED   7925021
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Nov 27, 2020 this sequence version replaced NM_019316.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: U56241.1, SRR23984936.297380.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1921              JAXUCZ010000003.1  169417890-169419810 c
FEATURES             Location/Qualifiers
     source          1..1921
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q42"
     gene            1..1921
                     /gene="Mafb"
                     /gene_synonym="b-maf; Krml"
                     /note="MAF bZIP transcription factor B"
                     /db_xref="GeneID:54264"
                     /db_xref="RGD:2982"
     exon            1..1921
                     /gene="Mafb"
                     /gene_synonym="b-maf; Krml"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..1006
                     /gene="Mafb"
                     /gene_synonym="b-maf; Krml"
                     /note="maf-B; transcription factor Maf-1; v-maf
                     musculoaponeurotic fibrosarcoma oncogene family, protein
                     B; Kreisler maf-related leucine zipper homolog (b-maf);
                     v-maf avian musculoaponeurotic fibrosarcoma oncogene
                     homolog B"
                     /codon_start=1
                     /product="transcription factor MafB"
                     /protein_id="NP_062189.1"
                     /db_xref="GeneID:54264"
                     /db_xref="RGD:2982"
                     /translation="MAAELSMGPELPTSPLAMEYVNDFDLLKFDVKKEPLGRAERPGR
                     PCTRLQPAGSVSSTPLSTPCSSVPSSPSFSPTEQKTHLEDLYWMASNYQQMNPEALNL
                     TPEDAVEALIGSHPVPQPLQSFDGFRSAHHHHHHHHPHPHHGYPGAGVTHDELGPHAH
                     PHHHHHHQASPPPSSAASPAQQLPTSHPGPGPHAAAAATAAGSNGSVEDRFSDDQLVS
                     MSVRELNRHLRGFTKDEVIRLKQKRRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQQ
                     VEQLKQEVSRLARERDAYKVKCEKLANSGFREAGSTSDSPSSPEFFL"
ORIGIN      
        1 ccgcggcagc ggcggctgag cctcgctttt agcgatggcc gcggagctga gcatggggcc
       61 agagctgccc accagcccgc tggccatgga gtacgtcaac gacttcgacc ttctcaagtt
      121 cgacgtgaag aaggagccac tggggcgtgc ggagcgtccc ggccggccat gcacacgcct
      181 gcagccggct ggttcggtgt cgtccacccc gctcagcaca ccgtgcagct ccgtgccttc
      241 ttctcccagc ttcagtccga ctgaacagaa gacccatctc gaggacctct actggatggc
      301 gagcaactac cagcagatga atcccgaggc actcaacctg acacccgagg acgcggtgga
      361 ggcgctcatc ggctcgcacc cagtgccaca gccgctgcag agcttcgacg gcttccgtag
      421 tgcgcaccac catcaccacc accaccaccc tcatccgcac cacgggtacc caggagccgg
      481 tgtgactcac gatgagctgg gcccgcacgc tcacccgcac catcaccacc atcaccaagc
      541 atcaccgccg ccgtccagcg ctgccagtcc ggcgcaacag ctgcccacta gtcacccggg
      601 gccgggaccg cacgcggcag ccgcggcgac ggctgcgggc agcaacggta gtgtggagga
      661 ccgcttctct gacgaccagc tggtgtccat gtccgtgcgt gagctgaacc gccacctgcg
      721 gggcttcacc aaggacgagg tgatccgcct gaagcagaag cggcggaccc tgaagaaccg
      781 gggctacgcc cagtcgtgca ggtataaacg cgtccagcag aaacatcacc tggagaacga
      841 gaagacgcag ctcattcagc aggtggagca gcttaagcag gaggtgtccc ggctggcccg
      901 cgagagagac gcctacaagg tcaagtgcga gaaactcgcc aactccggct tcagggaggc
      961 gggctccacc agcgacagcc cctcctctcc tgagttcttt ctgtgagtcg tagcgggtcc
     1021 cggcccccgc cattgccctg gcccggactc cctatcctgt gtccccagcc ctggactccc
     1081 tgtccctgcc atggccccgg ccttgacctg cctgactcga gctagaggga ggaaggacgc
     1141 gcgggccgcg ggagacgggc gggagcacgg gcgggtagag caccttggct aagaagaggg
     1201 cagcgcagcc tcttagactt gggcagagtt agagagaccc gggcggtggg aggtcccgga
     1261 gtaacttttc tccaagctgg aagcccgcga ggcatattcc aaggagtcgc caaggccgtc
     1321 cggacacttc tggctctgag aactttgtga gtgccagggc cgccgctttg cagcccagaa
     1381 ctcagttcgc ccccaggaag agcagaggag aggagaggga ctctggagtc cccgtgggcg
     1441 cgaggcaagg ctgagctaag gaaggaaaaa cggacagctc tgtctgtcca gagtatggtg
     1501 aacactggct ctcagccgga gacgcgggcc tcagttagga ctttcggcgc gcgaaggaaa
     1561 aaaaaaatct catcagtttt aatgcctgct cgattatata gaaaaaatac gaaaatctgc
     1621 attaaaaata ttaatcctgc atgctggaca tgtatggtaa taatttctat tttgtaccat
     1681 ttttcttgtt taactttagc atgttgttga tcatgaatca taaccccctt gtttctttgg
     1741 gtgagaaggg atgcagttcc tgcggctgcg gctgcgagcg agcaagcgag cggagtttca
     1801 gtcgccggcc ggcttgtaaa ttacccgccc ggccaaacca cattgagaag gtagcagcaa
     1861 gctgagtcta tgtttgggtt tattattatg gcattttttt gtttgtaagt aaaaataaag
     1921 g
//
