LOCUS       NM_001108857            1559 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus maelstrom spermatogenic transposon silencer
            (Mael), mRNA.
ACCESSION   NM_001108857 XM_001075736 XM_344169
VERSION     NM_001108857.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1559)
  AUTHORS   Takebe M, Onohara Y and Yokota S.
  TITLE     Expression of MAEL in nuage and non-nuage compartments of rat
            spermatogenic cells and colocalization with DDX4, DDX25 and MIWI
  JOURNAL   Histochem Cell Biol 140 (2), 169-181 (2013)
   PUBMED   23412502
  REMARK    GeneRIF: The MAEL seems to function in nuage and non-nuage
            structures and interacts with MIWI.
REFERENCE   2  (bases 1 to 1559)
  AUTHORS   Aravin AA, van der Heijden GW, Castaneda J, Vagin VV, Hannon GJ and
            Bortvin A.
  TITLE     Cytoplasmic compartmentalization of the fetal piRNA pathway in mice
  JOURNAL   PLoS Genet 5 (12), e1000764 (2009)
   PUBMED   20011505
REFERENCE   3  (bases 1 to 1559)
  AUTHORS   Soper SF, van der Heijden GW, Hardiman TC, Goodheart M, Martin SL,
            de Boer P and Bortvin A.
  TITLE     Mouse maelstrom, a component of nuage, is essential for
            spermatogenesis and transposon repression in meiosis
  JOURNAL   Dev Cell 15 (2), 285-297 (2008)
   PUBMED   18694567
REFERENCE   4  (bases 1 to 1559)
  AUTHORS   Costa Y, Speed RM, Gautier P, Semple CA, Maratou K, Turner JM and
            Cooke HJ.
  TITLE     Mouse MAELSTROM: the link between meiotic silencing of unsynapsed
            chromatin and microRNA pathway?
  JOURNAL   Hum Mol Genet 15 (15), 2324-2334 (2006)
   PUBMED   16787967
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473958.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_344169.3, XM_001075736.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1559
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q23"
     gene            1..1559
                     /gene="Mael"
                     /gene_synonym="RGD1309333"
                     /note="maelstrom spermatogenic transposon silencer"
                     /db_xref="GeneID:364039"
                     /db_xref="RGD:1309333"
     exon            1..214
                     /gene="Mael"
                     /gene_synonym="RGD1309333"
                     /inference="alignment:Splign:2.1.0"
     CDS             83..1387
                     /gene="Mael"
                     /gene_synonym="RGD1309333"
                     /note="maelstrom homolog"
                     /codon_start=1
                     /product="protein maelstrom homolog"
                     /protein_id="NP_001102327.1"
                     /db_xref="GeneID:364039"
                     /db_xref="RGD:1309333"
                     /translation="MPNRRASRNAYYFFVQEKIPELRRRGLPVARVADAIPYCSADWA
                     LLREDEKEKYSEMAREWRAAQGKDSGPSEKQKLVSTPLRRPGMLVPKPSVSPPDMSNL
                     SIKSDQALLGGVFYFLNIFSHGELPPHCEQRFLPCEIGCVKYSLQEGIMADFHSFINP
                     GEIPRGFRFHCQAASDSSHKIPISNFEFGHDQATVLQNLYKFIHPNPGNWPPIYCKSD
                     DRARVNWCLKRMERASEIRQDLELLTVEDLVVGIYQQKFLKEPSKTWVRSLLDVAMWD
                     YSSNTRCKWHEENDILFCALAVCKKIAYCISNSLATLFGIQLTGAHVPLQDYEASNSV
                     TPKMVVLDAGRYQKLRVESPGFCHFNSYNQEQRSNSSTGYYPSGVKISGSNSSVRGRG
                     ITRLLESISNSSNNIHRFSNCEASLSPYMPQKDGYKPFSSFS"
     exon            215..307
                     /gene="Mael"
                     /gene_synonym="RGD1309333"
                     /inference="alignment:Splign:2.1.0"
     exon            308..407
                     /gene="Mael"
                     /gene_synonym="RGD1309333"
                     /inference="alignment:Splign:2.1.0"
     exon            408..563
                     /gene="Mael"
                     /gene_synonym="RGD1309333"
                     /inference="alignment:Splign:2.1.0"
     exon            564..605
                     /gene="Mael"
                     /gene_synonym="RGD1309333"
                     /inference="alignment:Splign:2.1.0"
     exon            606..730
                     /gene="Mael"
                     /gene_synonym="RGD1309333"
                     /inference="alignment:Splign:2.1.0"
     exon            731..785
                     /gene="Mael"
                     /gene_synonym="RGD1309333"
                     /inference="alignment:Splign:2.1.0"
     exon            786..927
                     /gene="Mael"
                     /gene_synonym="RGD1309333"
                     /inference="alignment:Splign:2.1.0"
     exon            928..990
                     /gene="Mael"
                     /gene_synonym="RGD1309333"
                     /inference="alignment:Splign:2.1.0"
     exon            991..1123
                     /gene="Mael"
                     /gene_synonym="RGD1309333"
                     /inference="alignment:Splign:2.1.0"
     exon            1124..1199
                     /gene="Mael"
                     /gene_synonym="RGD1309333"
                     /inference="alignment:Splign:2.1.0"
     exon            1200..1559
                     /gene="Mael"
                     /gene_synonym="RGD1309333"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctcggttac taagggcggg agcccggcga gggcgccggc tgcttgctgc gtctctggag
       61 ggcgtcgagg cccgacgacg ccatgcccaa ccgcagggcc agccgcaatg cctactattt
      121 cttcgtacag gagaagattc ccgaactgcg ccggcgaggc ctgccggtgg cccgcgtggc
      181 agacgccatc ccctactgct cggccgactg ggcgctcctg agggaggatg agaaggagaa
      241 atactcagaa atggctcgag agtggagagc agcccaggga aaggattctg ggccttcaga
      301 gaagcagaaa ctcgtatcca caccactgag gaggccaggc atgcttgtac caaaaccaag
      361 tgtttctccc cctgatatgt caaatttatc tataaaaagt gatcaagctc tccttggagg
      421 tgttttttat tttctgaata tttttagcca tggtgagcta cctcctcatt gtgaacagcg
      481 cttcctccct tgtgaaattg gctgtgtcaa atattccctc caggaaggta ttatggcaga
      541 tttccacagc tttatcaatc caggtgaaat tccacgagga tttcggttcc attgccaggc
      601 tgcaagtgat tctagtcaca aaattcctat ttcaaacttt gaattcgggc atgaccaagc
      661 aactgtgcta caaaacctct ataaatttat tcacccaaac ccagggaact ggccacctat
      721 ttactgcaag tctgatgaca gagccagagt caactggtgt ttgaagcgta tggagcgggc
      781 atcagaaata aggcaagatc tagaacttct cactgtagag gaccttgtag tgggaatcta
      841 ccagcaaaaa ttcctcaagg agccctctaa aacctgggtt cgaagcctcc tagatgtggc
      901 catgtgggac tattctagca acacgaggtg caagtggcat gaagaaaatg atattctctt
      961 ctgtgcttta gctgtttgca agaaaatcgc gtactgcatc agtaattctc tggccactct
     1021 ctttggaatc cagctcactg gagctcatgt accactacaa gactatgagg ccagcaatag
     1081 tgtgacaccc aaaatggttg tattagatgc agggcggtac cagaaactaa gagttgagag
     1141 tccaggattc tgtcatttca actcttacaa tcaggaacaa agatcaaact catctactgg
     1201 ttattaccca tctggggtga aaatttcggg ctcgaacagc agcgttcgag gaagagggat
     1261 tacccgctta ctagagagca tctcaaactc ctctaacaac atccacagat tctccaactg
     1321 tgaggcctca ctctcacctt acatgcccca aaaagatggg tacaaacctt tttcctcctt
     1381 ttcgtaatga tggtactctg tgcaatttct ggaaaaaaac aagcccaact tcctttctga
     1441 ctacagtcat attaacaaac atcacatcaa tagtaaatgc cactcctaaa atctacttaa
     1501 tttgtaagga aactatttca tagattaaaa taattgtggt tggagaagat cttggcatt
//
