LOCUS       XM_039106853            4867 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus mono-ADP ribosylhydrolase 2 (Macrod2),
            transcript variant X1, mRNA.
ACCESSION   XM_039106853
VERSION     XM_039106853.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051338.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039106853.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4867
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4867
                     /gene="Macrod2"
                     /note="mono-ADP ribosylhydrolase 2; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 14
                     ESTs, 1 Protein, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 26 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:685695"
                     /db_xref="RGD:1591318"
     CDS             359..1804
                     /gene="Macrod2"
                     /codon_start=1
                     /product="ADP-ribose glycohydrolase MACROD2 isoform X1"
                     /protein_id="XP_038962781.1"
                     /db_xref="GeneID:685695"
                     /db_xref="RGD:1591318"
                     /translation="MYPSNKKKKVWREEKERLLKMTLEERRKEYIRDYVSLSTILSWK
                     EEMKSKGQNDEENAQEAPQVKKSLSEKVSLYRGDITLLEVDAIVNAANASLLGGGGVD
                     GCIHRAAGPCLLAECRNLNGCETGHAKITCGYDLPAKYVIHTVGPIARGHINGSHKED
                     LANCYQSSLKLVKENNLRSVAFPCISTGIYGFPNEPAAIIALGTIKEWLAKNHQEVDR
                     IIFCVFLEVDFKIYKKKMNEFFPIDDNNEGAADADTKEEAEGPEPKGLSPPHKKSKAK
                     KLESSKDSNEVLLKDESGPEEKQTAEGMEGQSQEAGGLRVLLRSLLGLIHRDGVNTTP
                     VPSPASEDKAEVHKDEADSAKDDNTTKESEVTNHSVCDQELPNGQENDSTKSEGKTET
                     ESPSSSMETEDLSPNQEDATIVEEPEVIPLIDDQEEQEGGEAQGEEAPAVFAESQGSS
                     EAENTSGPDVDMNSQVDGVNEMTESLQEDLQ"
ORIGIN      
        1 cctgaggctg aagtccgggc gtgccttggc tagaacgcgg agagcggcgg gcggagcagc
       61 caatgggcgg cggcgctgcc tagctgccgg gaggcggggc ctgtgcgggt gttaggttag
      121 cgcgaggcgt gacctagttg acaggctctg aggtgctgct gtggcggcgg cggccgggca
      181 gagcgggcgg gttgagggag gagggcggcg acgggccagc ggctagcggc gcgggacgca
      241 gagcctttgc acttttccct cccgagtgtc cccccacatc ccccccacac tccacacacc
      301 ctgtttgccc gtgagcctgg ggaacttgca gcttaaagcc agccaccccc acggcagcat
      361 gtaccccagc aacaagaaga aaaaggtgtg gagagaggag aaagaacgtt tgctgaagat
      421 gaccttagag gagagacgca aagaatacat aagggactat gtttctctga gcaccattct
      481 gtcatggaag gaagagatga agagcaaagg ccaaaatgat gaagaaaatg ctcaggaagc
      541 accacaggtg aagaaaagct tgagtgaaaa ggtttctctc tacagaggtg acatcaccct
      601 gctagaggtg gatgcaatcg tcaatgcggc aaatgccagt cttcttggag gaggtggtgt
      661 ggatggctgt attcacagag ctgccggccc ctgtttgtta gccgagtgtc ggaacctgaa
      721 cggctgtgag accggacatg caaaaatcac atgtggctac gacctccctg caaagtatgt
      781 catccacacc gtagggccaa tagccagagg ccacatcaat ggttcccaca aggaagacct
      841 tgcaaattgc tatcaatcat ccttgaagct ggtgaaagaa aataacctcc gatcagttgc
      901 atttccctgc atttcaacgg gcatttatgg ttttccgaat gagcctgcgg caatcattgc
      961 cctaggaaca attaaggaat ggctcgccaa gaatcatcag gaggtggatc ggatcatctt
     1021 ctgtgtcttc ctagaagttg atttcaaaat ctacaaaaag aaaatgaatg agttcttccc
     1081 cattgatgat aacaatgaag gagcagcaga tgctgacacg aaggaagagg cagaagggcc
     1141 agagcctaaa ggcctttctc cgccccataa gaagagcaaa gcaaagaaac tggaaagttc
     1201 gaaagactcc aatgaagttt tgttgaaaga tgaaagtggt ccagaggaaa agcaaactgc
     1261 ggaaggaatg gaggggcaga gccaagaagc aggtgggctc agggttcttt tgaggagtct
     1321 cctaggcctc atccacagag atggtgtcaa caccacccca gtgcccagcc ctgcttctga
     1381 agacaaagct gaagtccata aagatgaagc agattctgca aaggatgaca ataccacaaa
     1441 agagagtgag gtgaccaatc attctgtgtg cgaccaagaa cttcccaatg gacaagagaa
     1501 tgactcaaca aagagtgagg gaaaaactga gacagagtcc ccaagctcct ctatggagac
     1561 agaagacctt tcaccaaatc aagaagatgc cacgattgtg gaagaaccag aagtgatccc
     1621 cctgatagat gaccaggaag aacaggaagg tggagaagct caaggcgagg aagcacctgc
     1681 tgtgtttgct gaaagccaag gttccagcga ggcagaaaac acttcaggtc ctgatgttga
     1741 catgaacagt caggtggatg gtgtaaatga gatgacagag agtctgcagg aagatctcca
     1801 atagggccac aagatgaagc aaaggaacaa agaactgaag ctaaatgaca gccctcagca
     1861 tggcaaggcc tggccctggg ggacttggga agaagatagt gtgtgctgtg gaagggggtg
     1921 ggggaggggg gaaagtaagt tcgtggaaga aagggggtcc tttgctctaa ttctccagct
     1981 gcattttgtt gtttacctac agacaagaaa aaaaatgaaa aaacaaaaca aaaagaaaag
     2041 acaagaaaaa agaaaaagca agtgagctcc ctccatatgt gtgaggaggc cccatgctga
     2101 gcatttttca ggcaccagtc cctatcattt ctgtcttttc ttcatgcctc acccttaggg
     2161 ccatggtgat agggttaata ctcacccagg tctcctggtc cctctctgct ttctcggttc
     2221 tctcacaaaa ctggttacag gacgatgcgt cccttgaaaa agaaggaatg taatgacaag
     2281 ctgcaggcta aagttcaagt tgcccagcac tggtgtaatc tactgacgaa ggaggaaggg
     2341 cagaaacggt tacaaattga ataaccattg gaggaggtct gataaggaac tcaaaatatt
     2401 caaatcaggc attaacaaag ctcagtgttg gcagccacta gaacctccat ccatcacacc
     2461 caggatgccg tgtgtgttca tttttgacac tgatttcagg caatgcttcc ttggttgatg
     2521 aggttgttac tgcttccata tggagccaat caccaagata tggtcctttg tacacgattg
     2581 gaatgggtgt tactatcatt gagataaagg ggaggggctt gcttcattta ggtctcaaat
     2641 aaatctatta ataacaattt tagtcatcaa agttccactt gaagtctcta ctcttcataa
     2701 aaagaatatc catggtgatc caagatgtga tggccttcag aggctcacac ttgaagttac
     2761 atttggagcc attacttcca gccttggctt cctggtctgc taatgccaaa tccaagggtg
     2821 atttgatggc ttatccattc atccaaatct tagtcagaac tatccacaac ataaggagca
     2881 agtagagcag tcgaagttca agcaatgagg accagaggag gctggacatc atcccaagta
     2941 tccatcccag aacaaacctc ggtctcacac tgcctcttgg ggttccaaag acatgctagt
     3001 gtcttttgca tactatctta actccagagt cttttagaat catgatgttt tatgttgcta
     3061 ttcctaacag agaggggaaa gtggaactaa ctgagaatat ctaaagaaga cagtgaaatg
     3121 gtaccacttc ataagtatct cattcaattc accagctttg ccctttcctg tggaaaatcc
     3181 atcttatctt cctgtgacta gttttgcctg ctctgcatta atttctgttt ctaagcaaac
     3241 catacctctg agtatgttac cttttaacat ctcattttca ttaacatagt tcatcaacat
     3301 aataacaagg ctgtttcagg aatttcacat ttctccatgg cttttgcttt ttcttttcct
     3361 cctctttcaa cagtttgaca tgatagcata tacctctcca ttacccgttg ttttctagaa
     3421 caatgcttcc tctaaataat ctaagaagcc atccagatag atcgcttcaa tgtttcttac
     3481 catcttcaca gctattttac aagcacccac catttttgtg aagtgcctga cagatgagag
     3541 aaccatgcta gaaaggttcc ggatggggga gtgttactgt ccctcctgaa tagggtcaca
     3601 gtgggaaggc acgcctgaga gaagaggaat agccaggact gagacaattc cagcccacct
     3661 ttctcattac caatggcagc ctttgtgttt gctcattttg tgtgggaatg gattaagaaa
     3721 cagggagaga aaagtctgtg gaaactgtag gaaaaggaaa ggaatcttta gatttaggaa
     3781 acagagaagg agtcccaaac tcctgaattt gcttaaactt ccttttatga attaaagtgc
     3841 attttcatct ttgctttgca gtagattttt ggttgctacg tggctgaatg attgtatgct
     3901 ttaaaataaa taatgcagtt aatttacact tcaataatga aatataaaaa ttttagctct
     3961 gggccagact gaaggcatct cagacaagga aacccattat tcactggccc tgtcactgca
     4021 caggctgtac aaggtagtac atgatgggaa gtgaaccaat gctttctgca catgaatgct
     4081 ggatggccat ttccaaacac acttcagctg ggccacatga cataaagggc aataggggga
     4141 tgggaggaaa gtagccctgt tattagtcat gttttcatac agaggattga agtagacctt
     4201 caacataata gtcttaatta aaaaggtact cactgcagac tagacaaagg ggcttttcct
     4261 cttactgata actattcaga tgatggacat gtcttctttg ataaaagctt acaaagaaga
     4321 cctccaaagc actgtctatg atactgggtc acatattaat cactgcagct aattgtaaat
     4381 ctttctatga aacactgaaa agcctctttg tgaattaata cagttctgct tgatgcactt
     4441 ggtttgcaaa gacatttctc tgtatgtggt gcatgtcagc tgtgctttga aaaacaacaa
     4501 agttagcaga atatgttcaa tatattttct cgggaaatag ggtttttatc atatgactca
     4561 ttaaggattt gccttaccct gacatttgtg atataaagga aaaatcagga aaaaagtaat
     4621 tttcttgaac aagatatgtt tttacttaat gcaaataaat gtagtctgtt gcttgcaagg
     4681 aaaaaaatgt cttctggtat tactagggta acacgtgcct cttttgttaa agcagtcttg
     4741 aaatgctgga cagcttctga gtctgtttgt ctcttttcat ctgtgccaca cactatgaca
     4801 cttaaatgac tgttgccttc gaactatatt tgttagagca gagtgcaaat aaacttcttt
     4861 gagagga
//
