LOCUS       NM_001109086            2797 bp    mRNA    linear   ROD 17-JUL-2023
DEFINITION  Rattus norvegicus macrophage immunometabolism regulator (Macir),
            mRNA.
ACCESSION   NM_001109086 XM_001070947 XM_576623
VERSION     NM_001109086.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2797)
  AUTHORS   Dorris ER, Tazzyman SJ, Moylett J, Ramamoorthi N, Hackney J,
            Townsend M, Muthana M, Lewis MJ, Pitzalis C and Wilson AG.
  TITLE     The Autoimmune Susceptibility Gene C5orf30 Regulates
            Macrophage-Mediated Resolution of Inflammation
  JOURNAL   J Immunol 202 (4), 1069-1078 (2019)
   PUBMED   30659109
REFERENCE   2  (bases 1 to 2797)
  AUTHORS   Muthana M, Hawtree S, Wilshaw A, Linehan E, Roberts H, Khetan S,
            Adeleke G, Wright F, Akil M, Fearon U, Veale D, Ciani B and Wilson
            AG.
  TITLE     C5orf30 is a negative regulator of tissue damage in rheumatoid
            arthritis
  JOURNAL   Proc Natl Acad Sci U S A 112 (37), 11618-11623 (2015)
   PUBMED   26316022
REFERENCE   3  (bases 1 to 2797)
  AUTHORS   Wright KJ, Baye LM, Olivier-Mason A, Mukhopadhyay S, Sang L, Kwong
            M, Wang W, Pretorius PR, Sheffield VC, Sengupta P, Slusarski DC and
            Jackson PK.
  TITLE     An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the
            primary cilium
  JOURNAL   Genes Dev 25 (22), 2347-2360 (2011)
   PUBMED   22085962
REFERENCE   4  (bases 1 to 2797)
  AUTHORS   Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M,
            Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail
            S, Li P and Sutton G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473997.2.
            
            On or before Dec 21, 2007 this sequence version replaced
            XM_576623.2, XM_001070947.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ218309.1, FQ210387.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2797
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q36"
     gene            1..2797
                     /gene="Macir"
                     /gene_synonym="RGD1562136"
                     /note="macrophage immunometabolism regulator"
                     /db_xref="GeneID:501195"
                     /db_xref="RGD:1562136"
     exon            1..244
                     /gene="Macir"
                     /gene_synonym="RGD1562136"
                     /inference="alignment:Splign:2.1.0"
     exon            245..334
                     /gene="Macir"
                     /gene_synonym="RGD1562136"
                     /inference="alignment:Splign:2.1.0"
     exon            335..2797
                     /gene="Macir"
                     /gene_synonym="RGD1562136"
                     /inference="alignment:Splign:2.1.0"
     CDS             358..981
                     /gene="Macir"
                     /gene_synonym="RGD1562136"
                     /note="UNC119-binding protein C5orf30 homolog"
                     /codon_start=1
                     /product="macrophage immunometabolism regulator"
                     /protein_id="NP_001102556.1"
                     /db_xref="GeneID:501195"
                     /db_xref="RGD:1562136"
                     /translation="MEMDVNGEPRSTLTTLPLPAAEGSSPGKAEAEKPRCSSTPCSPM
                     RRTVSGYQILHMDSNYLVGFTTGEELLKLAQKCTGGEDSKGEAMPPLRSRQLDAGLAR
                     SSRLYKTRSRYYQPYEIPAVNGRRRRRMPSSGDKCTKSLPYEPYKALHGPLPLCLLKG
                     KRAHSKSLDYLNLDKMSIKEPADTEVLQYQLQHLTLRGDRVFARNNT"
ORIGIN      
        1 ttcccggcct cgcctccgca gccggcggga ggaggcggga aggcgggcgg aggcggggga
       61 ggaggcggga ctacggcggg ccgtagctgg cgccgagcgc ggtgggagag cagcgggtac
      121 ccggctggct cgactggcgg cctctgccca cacctcggcg ccgcagcccc gctcctcgcc
      181 cgcccttggc tcctggctct gcggccgccg gccatagagg agccggcgga accctggacg
      241 accgtgtctg gagtagaaca gaaaagttac tatgcctgtg ctccccaggg accctttgga
      301 acttacacag tgacgtcatc tgggatttag cctggggtgc gcagcctggt gcctaacatg
      361 gaaatggatg taaatgggga gcccagaagc accctgacca ccctgcccct gcccgcggct
      421 gaggggagct ctccaggaaa ggcggaggca gagaaaccgc gctgctccag cacgccgtgc
      481 tcccccatgc gtcggactgt gtctggttat cagatcctcc acatggactc taactacttg
      541 gttggcttca ccaccgggga ggagctcctg aagttagccc agaagtgcac gggaggggaa
      601 gacagcaagg gggaagccat gcctcccttg cgctctagac agctggatgc gggactggcg
      661 cgttcctccc gtctgtataa aactagaagt agatactatc agccatatga gatcccagct
      721 gtcaatggca gaaggcgaag gcggatgccc agctcaggag acaagtgcac caaatcccta
      781 ccttacgaac cctacaaggc cctccatggg cccctgcctc tatgtcttct taaaggtaag
      841 agggctcact ccaaatccct ggactacctc aatctagata aaatgagcat caaggagcca
      901 gctgacacgg aagtgctaca gtaccagctt cagcacctga ccctgcgagg ggaccgagtg
      961 ttcgctagaa acaatacatg aatggcttgc acaagaggtt tcaaccactt taggtcggcc
     1021 cgtactcggc tggaggaaaa tctgctgtcg tactctgtac atgaccttca cattagagat
     1081 ggttatatca gctaagtgtt cccgggacag aaaaattgtc tggatcaagt tttggataca
     1141 ggaatgaaat cacaggcact tggggcgggg cgggggggaa tatcattcta gagcacgaaa
     1201 ctgcaaagaa aaccgaatgt ttgaccgtga gtttgcatag ctttttagct aggaaaaggc
     1261 tttggtgcag gaatttcacc tttccggatt ctgacaccct aattgggaaa tgttacctgc
     1321 ttggttgttg ctaacttggt atgactcatt aggagtttat attcaagcac ccagtgcttc
     1381 ttggatctct gtatttcagt ataaaagtgt atgtaatgat tcgtcttacg aaatttagag
     1441 cttgaacacg gctgaactgg accacttttt atttttaaat attgagttta aatattttat
     1501 aactggtttt gcactgaaaa caattaacat ttcagataat taagagagta atctttcttc
     1561 acttgcctca gtgataatat tgagcgacgg attttttttt ttttaatttc cgcatggaaa
     1621 gttactgatc tttatggctg taaaatattc ctttctaagc attattaaag ttgtgtctta
     1681 gtaaaattaa atttgggata caaagtattt ctttcatgat gggtagcggg gtggggtgct
     1741 tttcccagaa tgtttccaac ttgaagtttc catcagttgg aaacatttcc tgagcgctta
     1801 gttatcaatt taaattccac gtggagcttg aacatgggag gattctcccc tgggctgtcg
     1861 gcacagtgct gcttgtattc tcacttcttg taagttgact ctaattctag cagaggagct
     1921 cctgactttg actatcaaat gcttaaacta agtctgaagt gacaccactc agcccagggt
     1981 cgccactctg tgcagggtga ttctcatcag aattttagtt tccggattag cctaggagcc
     2041 tagcatgctc ctactgtttt aatgggctaa tcctggatta cctaacagtt tatgtctgtc
     2101 acactggttt cgtttgttgc taaagaaata attccttgcc tttagtaaca gaagcagctc
     2161 aacgattctt gaccataaat gtgtgtaact ttccttctgt aaacatttct gtttctttta
     2221 ctcagtctta aaggtgcaat ttattactga tttggcaatt ctggctatat aggactacat
     2281 attttatgtt ttctttgggg gcactgtgag tttctaaggg gttagcagtc ttgcttataa
     2341 aacaagaata ctttttaatt gacgaattgg gccattcctg gaacaatcat aatttttcct
     2401 ctgtccagaa tggatggcaa cctttcctta gagcagaatt actcttagaa accccaggag
     2461 ctcttaatag agaggcagcc atgttggcaa catgtaagag agagctcagg agaggccggc
     2521 tcccagctta ctgcatcaat ccaagttttt ggtggctgga aagtttctgc tgtttctact
     2581 ttaaagcaaa ctgcaccttt gtaacatatt gtactgatga atggtcacta agattaactc
     2641 tatctataca gtcattagtt tgacaagtaa tagaatcctg tcagatgcca aagagttggg
     2701 atttttacct ttaatgatta aacaccgtta tttattgatg atttaccctc tggaactgta
     2761 ttgtttctaa ctgaaataaa agggtgatgt aaacaca
//
