LOCUS       NM_001135758           23524 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus microtubule-actin crosslinking factor 1 (Macf1),
            mRNA.
ACCESSION   NM_001135758 XM_342906
VERSION     NM_001135758.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 23524)
  AUTHORS   Ka,M. and Kim,W.Y.
  TITLE     Microtubule-Actin Crosslinking Factor 1 Is Required for Dendritic
            Arborization and Axon Outgrowth in the Developing Brain
  JOURNAL   Mol Neurobiol 53 (9), 6018-6032 (2016)
   PUBMED   26526844
REFERENCE   2  (bases 1 to 23524)
  AUTHORS   Ning,W., Yu,Y., Xu,H., Liu,X., Wang,D., Wang,J., Wang,Y. and
            Meng,W.
  TITLE     The CAMSAP3-ACF7 Complex Couples Noncentrosomal Microtubules with
            Actin Filaments to Coordinate Their Dynamics
  JOURNAL   Dev Cell 39 (1), 61-74 (2016)
   PUBMED   27693509
REFERENCE   3  (bases 1 to 23524)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 23524)
  AUTHORS   Burgo,A., Proux-Gillardeaux,V., Sotirakis,E., Bun,P., Casano,A.,
            Verraes,A., Liem,R.K., Formstecher,E., Coppey-Moisan,M. and
            Galli,T.
  TITLE     A molecular network for the transport of the TI-VAMP/VAMP7 vesicles
            from cell center to periphery
  JOURNAL   Dev Cell 23 (1), 166-180 (2012)
   PUBMED   22705394
REFERENCE   5  (bases 1 to 23524)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   6  (bases 1 to 23524)
  AUTHORS   Chen,H.J., Lin,C.M., Lin,C.S., Perez-Olle,R., Leung,C.L. and
            Liem,R.K.
  TITLE     The role of microtubule actin cross-linking factor 1 (MACF1) in the
            Wnt signaling pathway
  JOURNAL   Genes Dev 20 (14), 1933-1945 (2006)
   PUBMED   16815997
REFERENCE   7  (bases 1 to 23524)
  AUTHORS   Lin,C.M., Chen,H.J., Leung,C.L., Parry,D.A. and Liem,R.K.
  TITLE     Microtubule actin crosslinking factor 1b: a novel plakin that
            localizes to the Golgi complex
  JOURNAL   J Cell Sci 118 (Pt 16), 3727-3738 (2005)
   PUBMED   16076900
REFERENCE   8  (bases 1 to 23524)
  AUTHORS   Kakinuma,T., Ichikawa,H., Tsukada,Y., Nakamura,T. and Toh,B.H.
  TITLE     Interaction between p230 and MACF1 is associated with transport of
            a glycosyl phosphatidyl inositol-anchored protein from the Golgi to
            the cell periphery
  JOURNAL   Exp Cell Res 298 (2), 388-398 (2004)
   PUBMED   15265687
REFERENCE   9  (bases 1 to 23524)
  AUTHORS   Kodama,A., Karakesisoglou,I., Wong,E., Vaezi,A. and Fuchs,E.
  TITLE     ACF7: an essential integrator of microtubule dynamics
  JOURNAL   Cell 115 (3), 343-354 (2003)
   PUBMED   14636561
REFERENCE   10 (bases 1 to 23524)
  AUTHORS   Sun,Y., Zhang,J., Kraeft,S.K., Auclair,D., Chang,M.S., Liu,Y.,
            Sutherland,R., Salgia,R., Griffin,J.D., Ferland,L.H. and Chen,L.B.
  TITLE     Molecular cloning and characterization of human trabeculin-alpha, a
            giant protein defining a new family of actin-binding proteins
  JOURNAL   J Biol Chem 274 (47), 33522-33530 (1999)
   PUBMED   10559237
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Feb 25, 2022 this sequence version replaced NM_001135758.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760389
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on computational evidence
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-124               JAXUCZ010000005.1  141233767-141233890 c
            125-396             JAXUCZ010000005.1  141230320-141230591 c
            397-458             JAXUCZ010000005.1  141098819-141098880 c
            459-548             JAXUCZ010000005.1  141092380-141092469 c
            549-626             JAXUCZ010000005.1  141088181-141088258 c
            627-719             JAXUCZ010000005.1  141084165-141084257 c
            720-886             JAXUCZ010000005.1  141064790-141064956 c
            887-999             JAXUCZ010000005.1  141063979-141064091 c
            1000-1106           JAXUCZ010000005.1  141063775-141063881 c
            1107-1226           JAXUCZ010000005.1  141063076-141063195 c
            1227-1322           JAXUCZ010000005.1  141062827-141062922 c
            1323-1450           JAXUCZ010000005.1  141062142-141062269 c
            1451-1544           JAXUCZ010000005.1  141061974-141062067 c
            1545-1699           JAXUCZ010000005.1  141061629-141061783 c
            1700-1976           JAXUCZ010000005.1  141060757-141061033 c
            1977-2105           JAXUCZ010000005.1  141059372-141059500 c
            2106-2183           JAXUCZ010000005.1  141058295-141058372 c
            2184-2345           JAXUCZ010000005.1  141056830-141056991 c
            2346-2450           JAXUCZ010000005.1  141054992-141055096 c
            2451-2546           JAXUCZ010000005.1  141053909-141054004 c
            2547-2672           JAXUCZ010000005.1  141052735-141052860 c
            2673-2825           JAXUCZ010000005.1  141050474-141050626 c
            2826-2980           JAXUCZ010000005.1  141048349-141048503 c
            2981-3107           JAXUCZ010000005.1  141046747-141046873 c
            3108-3291           JAXUCZ010000005.1  141045839-141046022 c
            3292-3461           JAXUCZ010000005.1  141045353-141045522 c
            3462-3640           JAXUCZ010000005.1  141044907-141045085 c
            3641-3779           JAXUCZ010000005.1  141043969-141044107 c
            3780-3973           JAXUCZ010000005.1  141043145-141043338 c
            3974-4136           JAXUCZ010000005.1  141041773-141041935 c
            4137-4220           JAXUCZ010000005.1  141040886-141040969 c
            4221-4328           JAXUCZ010000005.1  141040279-141040386 c
            4329-4427           JAXUCZ010000005.1  141039960-141040058 c
            4428-4580           JAXUCZ010000005.1  141039530-141039682 c
            4581-4669           JAXUCZ010000005.1  141039156-141039244 c
            4670-4805           JAXUCZ010000005.1  141035240-141035375 c
            4806-10124          JAXUCZ010000005.1  141026236-141031554 c
            10125-10274         JAXUCZ010000005.1  141024925-141025074 c
            10275-10490         JAXUCZ010000005.1  141021315-141021530 c
            10491-10640         JAXUCZ010000005.1  141020782-141020931 c
            10641-10874         JAXUCZ010000005.1  141018760-141018993 c
            10875-11024         JAXUCZ010000005.1  141016210-141016359 c
            11025-11258         JAXUCZ010000005.1  141014054-141014287 c
            11259-11483         JAXUCZ010000005.1  141012668-141012892 c
            11484-12002         JAXUCZ010000005.1  141010591-141011109 c
            12003-12179         JAXUCZ010000005.1  141009421-141009597 c
            12180-12303         JAXUCZ010000005.1  141009113-141009236 c
            12304-12512         JAXUCZ010000005.1  141006842-141007050 c
            12513-12830         JAXUCZ010000005.1  141006065-141006382 c
            12831-12997         JAXUCZ010000005.1  141003725-141003891 c
            12998-13154         JAXUCZ010000005.1  141001885-141002041 c
            13155-13272         JAXUCZ010000005.1  140999166-140999283 c
            13273-13335         JAXUCZ010000005.1  140996048-140996110 c
            13336-13577         JAXUCZ010000005.1  140995011-140995252 c
            13578-13707         JAXUCZ010000005.1  140993933-140994062 c
            13708-13907         JAXUCZ010000005.1  140992502-140992701 c
            13908-14403         JAXUCZ010000005.1  140990356-140990851 c
            14404-15875         JAXUCZ010000005.1  140987685-140989156 c
            15876-16037         JAXUCZ010000005.1  140960112-140960273 c
            16038-16208         JAXUCZ010000005.1  140959744-140959914 c
            16209-16375         JAXUCZ010000005.1  140957859-140958025 c
            16376-16535         JAXUCZ010000005.1  140956074-140956233 c
            16536-16620         JAXUCZ010000005.1  140954396-140954480 c
            16621-16862         JAXUCZ010000005.1  140953491-140953732 c
            16863-17069         JAXUCZ010000005.1  140952410-140952616 c
            17070-17189         JAXUCZ010000005.1  140949070-140949189 c
            17190-17297         JAXUCZ010000005.1  140948559-140948666 c
            17298-17516         JAXUCZ010000005.1  140947173-140947391 c
            17517-17720         JAXUCZ010000005.1  140945494-140945697 c
            17721-17952         JAXUCZ010000005.1  140943752-140943983 c
            17953-18179         JAXUCZ010000005.1  140942951-140943177 c
            18180-18302         JAXUCZ010000005.1  140941716-140941838 c
            18303-18404         JAXUCZ010000005.1  140941523-140941624 c
            18405-18506         JAXUCZ010000005.1  140941044-140941145 c
            18507-18680         JAXUCZ010000005.1  140940780-140940953 c
            18681-18836         JAXUCZ010000005.1  140940540-140940695 c
            18837-19034         JAXUCZ010000005.1  140940219-140940416 c
            19035-19163         JAXUCZ010000005.1  140939670-140939798 c
            19164-19337         JAXUCZ010000005.1  140938882-140939055 c
            19338-19493         JAXUCZ010000005.1  140937025-140937180 c
            19494-19700         JAXUCZ010000005.1  140936713-140936919 c
            19701-19820         JAXUCZ010000005.1  140936465-140936584 c
            19821-19990         JAXUCZ010000005.1  140935559-140935728 c
            19991-20150         JAXUCZ010000005.1  140934850-140935009 c
            20151-20345         JAXUCZ010000005.1  140932943-140933137 c
            20346-20474         JAXUCZ010000005.1  140932527-140932655 c
            20475-20618         JAXUCZ010000005.1  140930887-140931030 c
            20619-20807         JAXUCZ010000005.1  140930115-140930303 c
            20808-20928         JAXUCZ010000005.1  140929013-140929133 c
            20929-21092         JAXUCZ010000005.1  140928195-140928358 c
            21093-21104         JAXUCZ010000005.1  140927235-140927246 c
            21105-21267         JAXUCZ010000005.1  140926301-140926463 c
            21268-21422         JAXUCZ010000005.1  140925274-140925428 c
            21423-21497         JAXUCZ010000005.1  140924111-140924185 c
            21498-21515         JAXUCZ010000005.1  140922605-140922622 c
            21516-21633         JAXUCZ010000005.1  140919552-140919669 c
            21634-21845         JAXUCZ010000005.1  140914157-140914368 c
            21846-21975         JAXUCZ010000005.1  140911066-140911195 c
            21976-23524         JAXUCZ010000005.1  140908829-140910377 c
FEATURES             Location/Qualifiers
     source          1..23524
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..23524
                     /gene="Macf1"
                     /note="microtubule-actin crosslinking factor 1"
                     /db_xref="GeneID:362587"
                     /db_xref="RGD:1306057"
     exon            1..124
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            125..396
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     CDS             177..22232
                     /gene="Macf1"
                     /note="actin cross-linking family 7"
                     /codon_start=1
                     /product="microtubule-actin cross-linking factor 1"
                     /protein_id="NP_001129230.2"
                     /db_xref="GeneID:362587"
                     /db_xref="RGD:1306057"
                     /translation="MSSSDEETLSERSCRSERSCRSERSYRSERSGSLSPCPPGDTLP
                     WNLPLHEQKKRKSQDSVLDPAERAVVRVADERDRVQKKTFTKWVNKHLMKVRKHINDL
                     YEDLRDGHNLISLLEVLSGIKLPREKGRMRFHRLQNVQIALDFLKQRQVKLVNIRNDD
                     ITDGNPKLTLGLIWTIILHFQISDIYISGESGDMSAKEKLLLWTQKVTAGYTGIKCTN
                     FSSCWSDGKMFNALIHRYRPDLVDMERVQIQSNRENLEQAFEVAERLGVTRLLDAEDV
                     DVPSPDEKSVITYVSSIYDAFPKVPEGGEGISATEVDSRWQEYQSRVDSLIPWIRQHT
                     ILMSDKSFPQNPVELKALYNQYIHFKETEILAKEREKGRIKELYKLLEVWIEFGRIKL
                     PQGYHPNHVEEEWGKLIVEMLEREKSLRPAVERLELLLQIANKIQNGALNCEEKLTLA
                     KNTLQADAAHLESGQPVQCESDVIMYIQECEGLIRQLQVDLQILRDEKYYQLEELAFR
                     VMRLQDELVTLRLECTNLYRKGHFTSLELVPPSTLTTTHLKAEPLNKTTHSSSTSWFR
                     KPMTRTELVAISSSEDEGSLRFVYELLSWVEEMQMKLERAEWGNDLPSVELQWETQQH
                     IHTSVEELGSSVKEARLYEGKMSQNFHTSYVETLGKLETQYCKLKETSSFRMRHLQSL
                     HKFVSKATAELIWLNGKEEEELACDWSDSNPNISAKKAYFSELTMELEGKQDVFRSLQ
                     DTAELLSLENHPAKQTVEAYSAAVQSQLQWMKQLCLCVEQHIKENAAYFQFFSDARDL
                     ESFLRNLQDSIKRKYTCDHNTSLSRLEDLLQDSMDEKEQLIQSKSSVASLVGRSKTIV
                     QLKPRNPDHVLKSTLSVKAICDYRQIEITICKNDECVLEDNSQRTKWKVISPTGNEAM
                     VPSVCLLIPPPNTEAIDVASRVEQSYQKVMALWHQLHINTKSLISWNYLRKDIDAVQT
                     WNLEKLRSSAPGECHQVMKNLQAHYEDFLQDSHDSALFSVADRLRIEEEVEACKTHFQ
                     QLMESMENEDKEETLAKVYISELKNIRLRLEECEQRLLKQIQSSASSKTDRDARQDVA
                     LRIAEQEHVQEDLKHLRSDLDAVSVKCTTFLQQSPSGSSATTLRSELNLMVEKMDHVY
                     GLSIVCLNKLKTIDVIVRSIQDAELLVKGYEIKLSQEEAVPADLSALESHRTTLQHWL
                     SDVKDKNSVFSVLDEEISKAKAVAEQLHHRAAEPNLDLERYQEKGSQLQERWHRVIAQ
                     LETRQSEVESIQEVLRDYRACHGTLIKWIEETTAQQEMMKPGQAEDSRVLSEQLSQQT
                     ELFAEIERNQTKLDQCQKLSQQYSTTVKDYELQLMTYKAFVESQQKSPGKRRRMISSS
                     DAITQEFMDLRTRYTALVTLTTQHVKYISDALRRLEEEEKVVEEEKQEHVEKVKDLLG
                     WVSTLARNTQGTTTSSRTSASTDIEKAILEQQVLAEELTTKKEQVSEAIKTSQIFLAK
                     HGHKLSEREKEQISEQLCALNKTYHDLCDGSANQLQQLQSELAQQTEQKGCRAVAGVI
                     DLGTVEIFPIFRAMQKGLIDQDTGLVLLESQVIMSGLIAPENSEKLSLEEGLTRNLIS
                     LPMYQHLLGLRDSLSLISSLTGTQGSLSVVEAIEKKIVSERFGLKVLEVHLATGGFSL
                     PPSENYINLEEAFHQGFIASWLHSELQSHLRTSKNLIDPNTAEKVGLLELMQRCISHQ
                     ESGLKLLPVKQLAGGMVSLKSGGKVSIFRAVQEGLIDRQVTVRLLEAQLFAGGIVDPR
                     TGHRLTAEEAVRHNLIDQDMACAILIRQLQTGGIIDTATGERMTIDEAVTNNLVAAKI
                     ALVILESLWSFMGLLLPESGEILPITDALEQGIVSNELAHKILHNRQQIEALFLPTIT
                     EVWSWEKATESGILDKDLANNLRSVCIPDMRPHIQLADSAEQSKVGVAAGKPPLSCQR
                     EGRTSREEKLLFQLMTHSYINAHTGQRLLLLDQELVEMLTSRDEYQVGLPEVFEIQPQ
                     RLDTSKDLQELDPGTISQISSARKPCESQFPSQSKGYPSQENCTQAKGERSVIGRECS
                     SAESPERELFVGEQGAITENVGSLKVINKVKLELQSPLLGSRKEEQTEMFSEENVSSD
                     PLLVECPEGSEDMSLVLDKDLSTEKSKCQAPTKSSFTRHKEQVKTVKADHIPSETGIP
                     LTKSQNKTSQVQVDASVSLKSEFKSEYDEKELNETLLVKGSHKQSQEGQSVPDGQMVV
                     LEKADTEDNGDEPSLLCSSPFEDATLSTLSAQLQDGGIFHEETGQKLLLNEAIAQGLV
                     SSHTAVKLMGKLNMFRGFFDSQTCESLTTEEVIDEGLMDEKLLCNVLMSDKAISGILD
                     PRTHSLCSVQEAVAAGLLDKETATRILEGQVITGGIVDLKRGKRLSVTLASNLGLVDT
                     TDQTELINLEKATKGRGAEKAVKERLIGLQMETTGLLDPESKAPLTVLQSIDRGLIER
                     EEAIYQLTKQVLDGGIIHHISGLRLSVDNAFKHGMIGEDVARQLRKVENFNHHQFFHP
                     QTKEALSFSEAIKLDLVSPDLKREIQEILDFSENLGDLIYGQKLTSVKANKEESLANK
                     TALPSRVIHGVIDPESCTTIPYSELVKKCRIDIESGWRYLEVIPLSDIKDEMSNKVLT
                     PSEAIQRGKVDFGSMLKVLEAQANTGGIIDMATGKRVTLASALEQKLIDENMARIIAS
                     HQVLTGGIIDIYNDQRVTLNDAVEKRLISPELATMIQADTLGKQGGTGVCELKGEFLR
                     NEFRKATRESYDKEKHEGVLQVGSQCAQEKANVRVSYGVKVGKGKKISVEMEGQRQDE
                     EKASSDNEVSASIVSPGGLEGESTHQVLVTHPCSGSSDLKLIEEARSPEVEQEEAVAR
                     MKMTPHVNRSTPGLDAGEARDCPGRVGSKGQESKHEPAGKLSSVQAANVEVGRRGRRE
                     TGGEERVQTNKVAAGPSEEELDQEVTIGDEHGSFVKSQPMKTIGNDRGKEGGREKDFS
                     LVCKTEGFPSQMTFKDASLENQNALMFFSEGETKTVNLCSILKQREKLSQETASIVQK
                     EPFSSEIPRPERLNSQESDGESHISDMPCISKGPMAAQITTRQETTDEQDLSITSKTA
                     ETKDRIFPSKNYKEKLLQEIPMDSTRAHKLKESTVSTLDTEGLGYLDSSDIKALHEDS
                     RADREFSGHQKSKITTTQEVKFLEVVNPLVRDAEGHRGSSKDRVAQRGPRTLASLLPE
                     KLPAGTAQSENTKQHDTVIIATTPEMREEMPLSLPCSPLKVDEQIPKEKHKELPGDER
                     ASCMATPSGKGSEGVKPAPCRATQNVFTRRLCLEHDEKLVSYLSLLRDIEMRTKQIQP
                     LELSVAELQDLLGQAKVLDRELKDLSTVVSQELECVDQIVISQPQEVPAQLLKALEKD
                     AKNLQKSLGSVRDSWSSRSLHLHNAVEVKKTTVLNWHKELEGKLQDLKAWVDRTSLTL
                     HSKGCDTQTDADSLSPTLQGYEDMKQSVAERKSQLDALALDTQLFISEHPQGLSLQQN
                     QQMLQFLSELQTSFQGLVEHTAAQKDVVQGHLQQVQQEVQVKTLQKQQDTCHKKLEDL
                     RSWVRQAERALERHRGRASQQELSALQQNQSDLKDLQGDIQNHSTSFATAVKDIEGFL
                     EENQNKLSPQELTALREKLYQAKEQYEGLQDRTREAQKELEEAVTSALQQETEKSKAA
                     TELAENRRKIDALLDWVTSVGSSDRQPQTSLPGTEQFSGACLEKQTLDATDGCVDVNQ
                     VPEKLDRQYELMKARHQELLSQQQNFIVATQSAQSFLDQHSHNLTPEERQMLQEKLGE
                     LKEQYAASLAQSEAKLRQTQTLRDELQKFLQDHREFENWLERSENELDGMHTGGSSPE
                     ALNSLLKRQGSFSEDVISHKGDLRFVTISGQKVLETENNFEEGQEPSPTRNLVNEKLK
                     DATERYTTLHSKCTRLGSHLNMLLGQYQQFQSSADSLQAWMLTCEASVEKLLSDTVAS
                     DPGILQQQLATTKQLQEELAEHQVPVEKLQKAAHDLMDIEGEPSLDCTPIRETTESIF
                     SRFQSLSCSLAERSALLQKAIAQSQSVQESMESLLQSMKEVEQNLEGEQVAALSSGLI
                     QEALANNMKLKQDIARQKSSLEATREMVTRFMETADGNSAAVLQDRLAELSQRFHRLQ
                     LQQQEKESGLKKLLPQAETFEQLSSKLQQFVEHKNRLLASGNQPDQDIAHFSQHIQEL
                     TLEMEDQKENLGTLEHLVTALGSCGFALDLSQHQEKIQNLKKDFTELQKTVQEREKDA
                     SNCQEQLDEFRKLIRTFQKWLKETEGNVPPAETFVSAKELEKQIEHLKGLLDDWAGKG
                     VLVEEINTKGTALESLIMDITAPDSQAKTGSVLPSVGSSVGSVNGYHTCKDLTEIQCD
                     MSDVNSKYDKLGDALRERQESLQTVLSRMEEVQKEASSVLQWLESKEEVLKGMDASLS
                     PTKTETVKAQAESNKAFLAELEQNSPKIQKVKEALAGLLEAYPNSQEAENWRKMQEDL
                     NSRWEKATEVTVARQKQLEESASHLACFQAAESQLRPWLMEKELMMGVLGPLSIDPNM
                     LNAQKQQVQFMLKEFEARRQQHEQLTEAAQGILTGPGDVSPSASQVHKDLQSISQKWV
                     ELTDKLNSRSTQIDQAIVKSTQYQDLLQDLSEKVKAVGQRLSGQSAISTQPDAVKQQL
                     EETSEIRSDLGQLDDEMKEAQTLCQELSLLIGEQYLKDELKKRLETVALPLQGLEDLA
                     ADRMNRLQAALASTQQFQQMFDELRTWLDEKQSQQAKNCPISAKLERLQSQLQENEEF
                     QKNLNQHSGSYEVIVAEGESLLLSVPPGEEKKTLQNQLVELKSHWEDLNKKTVDRQSR
                     LKDCMQKAQKYQWHVEDLVPWIKDCKSKMSELQVTLDPVQLESSLLRSKAMLNEAEKR
                     RSLLEILNSAADILINSSEIDEDEIRDEKAGLNQNMDAITEELQAKTGSLEEMTQRLK
                     EFQESFKNIEKKVEGAKHQLEIFDALGSQACSNKNLEKLKAQREVLQALDPQVDYLRD
                     FTRGLVEDAPDGSDASPLVHQAELAQQEFLEVKQRVNSSCLTMENKLEGIGQFHCRVR
                     EMFSQLADLDDELDGMGAIGRDTDSLQSQIEDIRLFLNKIQALRLDIEDSEAECRKML
                     EEEGTLDLLGLKRELEALNKQCGKLTERGKARQEQLELTLGRVEDFYSKLKALNDAAT
                     AAEEGEALQWIVGTEVDVINQQLADFKMFQKEQVDPLQVKLQQVNGLGQGLIQSAGKT
                     CDVQGLEHDMEEVNTRWNTLNKKVAQRIAQLQEALLHCGKFQDALEPLLSWLTDTEEL
                     IANQKPPSAEYKVVKAQIQEQKLLQRLLDDRKATVDMLQAEGGRIAQAAELADREKIT
                     GQLESLECRWTELLSKAAARQKQLEDILVLAKQFHETAEPISDFLSVTEKKLANSEPV
                     GTQTAKIHQQIIRHKALNEEIINRKKNVDQAIKNGQALLKQTTGEEVLLIQEKLDGIK
                     TRYADITVTSSKALRTLEQARQLATKFHSTYEELTGWLREVEEELAASGGQSPTGEQI
                     PQFQQRQKELKKEVMEHRLVLDTVNEVSHALLELVPWRAREGLDKLVSDANEQYKLVS
                     DTVGQRVDEIDAAIQRSQQYEQAADAELAWVAETKRKLMALGPIRLEQDQTTAQLQVQ
                     KAFSIDIIRHKDSMDELFSHRGEIFSTCGEEQKAVLQEKTECLIQQYEAVSLLNSERY
                     ARLERAQVLVNQFWETYEELSPWAEETLALIAQLPPPAVDHEQLRQQQEEMRQLRESI
                     AEHKPHIDKILKIGPQLKELNPEEGKMVEEKYQKAENMYAQIKDEVRQRALALDEAVS
                     QSAQFHDKIEPMLETLENLSSRLRMPPLIPAEVDKIRECISDNKSATMELEKLQPSFE
                     ALKRRGEELIGRSQGADKDLAAKEIQDKLDQMVFFWEDIKARSEEREIKFLDVLELAE
                     KFWYDMAALLTTIKDTQEIVHDLESPGIDPSIIKQQVEAAETIKEETDGLHEELEFIR
                     ILGADLIFACGETEKPEVKKSIDEMNNAWENLNRTWKERLEKLEDAMQAAVQYQDTLQ
                     AMFDWLDNTVIRLCTMPPVGTDLNTVKDQLNEMKEFKVEVYQQQIEMEKLNHQGELML
                     KKATDETDRDIIREPLTELKHLWENLGEKIAHRQHKLEGALLALGQFQHALEELMGWL
                     THTEELLDAQRPISGDPKVIEVELAKHHVLKNDVLAHQATVETVNKAGNELLESSAGD
                     DASSLRSRLETMNQCWESVLQKTEEREQQLQSTLQQAQGFHSEIEEFLLELNRMESQL
                     SASKPTGGLPETAREQLDAHMELHSQLRAKEEIYNQLLDKGRLMLLSRGDSGSGSKTE
                     QSVALLEQKWHVVSSKVEERKSKLEEALSLATEFQNSLQEFINWLTLAEQSLNIASPP
                     SLILNTVLSQIEEHKVFANEVNAHRDQIIELDQTGNQLKFLSQKQDVVLIKNLLVSVQ
                     SRWEKVVQRSIERGRSLDDARKRAKQFHEAWKKLIDWLEDAESHLDSELEISNDPDKI
                     KLQLSKHKEFQKTLGGKQPVYDTTIRTGRALKEKTLLADDAQKLDNLLGEVRDKWDTV
                     CGKSVERQHKLEEALLFSGQFMDALQALVDWLYKVEPQLAEDQPVHGDLDLVMNLMDA
                     HKVFQKELGKRTGTVQVLKRSGRELIESSRDDTTWVKGQLQELSTRWDTVCKLSVSKQ
                     SRLEQALKQAEEFRDTVHMLLEWLSEAEQTLRFRGALPDDTEALQSLIDTHKEFMKKV
                     EEKRVDVNAAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVLTWAKQHQQRLETAL
                     SELVANAELLEELLAWIQWAETTLIQRDQEPIPQNIDRVKALITEHQSFMEEMTRKQP
                     DVDRVTKTYKRKNIEPTHAPFIEKSRSGSRKSLNQPTPPPMPILSQSEAKNPRINQLS
                     ARWQQVWLLALERQRKLNDALDRLEELCPELKEFANFDFDVWRKKYMRWMNHKKSRVM
                     DFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYEFVAA
                     LHPNKDAYRPTTDADKIEDEVTRQVAQCKCAKRFQVEQIGENKYRFFLGNQFGDSQQL
                     RLVRILRSTVMVRVGGGWMALDEFLVKNDPCRARGRTNIELREKFILPEGASQGMTPF
                     RSRGRRSKPSSRAASPTRSSSSASQSNHSCTSMPSSPATPASGTKVISSTGSKLKRPT
                     PTFHSSRTSLAGDTSNSSSPASTGAKTNRADPKKSASRPGSRAGSRAGSRASSRRGSD
                     ASDFDLLETQSACSDTSESSAAGGQGSSRRGLTKPSKIPTMSKKTTTASPRTPCPKR"
     exon            397..458
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            459..548
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            549..626
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            627..719
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            720..886
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            887..999
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1000..1106
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..1226
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1227..1322
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1323..1450
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1451..1544
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1545..1699
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1700..1976
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1977..2105
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2106..2183
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2184..2345
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2346..2450
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2451..2546
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2547..2672
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2673..2825
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2826..2980
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2981..3107
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            3108..3291
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            3292..3461
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            3462..3640
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            3641..3779
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            3780..3973
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            3974..4136
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            4137..4220
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            4221..4328
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            4329..4427
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            4428..4580
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            4581..4669
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            4670..4805
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            4806..10124
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            10125..10274
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            10275..10490
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            10491..10640
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            10641..10874
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            10875..11024
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            11025..11258
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            11259..11483
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            11484..12002
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            12003..12179
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            12180..12303
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            12304..12512
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            12513..12830
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            12831..12997
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            12998..13154
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            13155..13272
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            13273..13335
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            13336..13577
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            13578..13707
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            13708..13907
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            13908..14403
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            14404..15875
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            15876..16037
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            16038..16208
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            16209..16375
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            16376..16535
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            16536..16620
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            16621..16862
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            16863..17069
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            17070..17189
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            17190..17297
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            17298..17516
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            17517..17720
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            17721..17952
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            17953..18179
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            18180..18302
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            18303..18404
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            18405..18506
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            18507..18680
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            18681..18836
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            18837..19034
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            19035..19163
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            19164..19337
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            19338..19493
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            19494..19700
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            19701..19820
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            19821..19990
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            19991..20150
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            20151..20345
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            20346..20474
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            20475..20618
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            20619..20807
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            20808..20928
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            20929..21092
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            21093..21104
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            21105..21267
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            21268..21422
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            21423..21497
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            21498..21515
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            21516..21633
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            21634..21845
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            21846..21975
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
     exon            21976..23524
                     /gene="Macf1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttcagccgc cgccgctagg gcgcgggggg cggggggctc ggcgccgcga gctcggccat
       61 tgtgggagcc gctcccctcc gccgcaccgc agccgcctgc cggcttcctc ctcacgctca
      121 caggatccct tctcccagga catctagtcc ttcctgtagc tactcctgct tggaccatgt
      181 cttcctctga tgaagaaacg ctcagtgagc gatcctgtcg gagtgagagg tcatgtcgta
      241 gcgagagatc gtacaggagt gagcggtcag ggagcctgtc tccctgtccc cctggggaca
      301 ccttgccctg gaacctgcca ctgcatgagc agaagaagcg gaaaagccag gattctgtgc
      361 tggaccctgc agaacgcgcc gtggtcagag ttgctgatga gcgggaccgg gtgcaaaaga
      421 aaacattcac caagtgggtc aacaagcact tgatgaaggt ccgcaagcac atcaatgatc
      481 tctatgaaga ccttcgggat ggacacaacc tgatctctct gttagaggtc ctctcgggca
      541 tcaaactgcc cagagaaaag ggcaggatgc gttttcacag gctgcagaat gtgcagattg
      601 ccctggactt cctaaagcag cggcaggtga agctagtgaa catccgcaat gatgacatca
      661 cggacggcaa tcccaagctc accctgggcc tcatctggac catcatcttg cacttccaga
      721 tctctgacat ctatattagt ggggagtcag gggatatgtc agccaaagag aagctactct
      781 tgtggactca gaaagtaaca gctggttaca caggaatcaa gtgcaccaac ttttcttcct
      841 gctggagcga tgggaaaatg ttcaatgcat tgattcaccg atacagacct gacctggtag
      901 atatggagag agtacaaatc cagagtaacc gggagaatct ggaacaggct ttcgaggtag
      961 ctgagagact tggtgtcacc cgattgctgg acgcagaaga tgtggatgtg ccatctccag
     1021 atgaaaagtc tgtaatcact tacgtgtctt ccatttacga tgccttcccc aaagtccctg
     1081 agggaggaga aggaatcagt gctacggaag tggactccag atggcaagaa taccaaagcc
     1141 gagtggactc actcattccc tggatcaggc agcatacaat cttgatgtca gataaatctt
     1201 ttccccagaa ccctgttgaa ctaaaggcac tttataacca atatatacac ttcaaagaaa
     1261 cggaaattct ggccaaggag agagaaaaag gaagaatcaa agagttatat aagttattag
     1321 aggtgtggat tgaatttggc agaattaagc tgcctcaagg ctaccaccct aatcatgtag
     1381 aagaagaatg ggggaaactc atcgttgaaa tgctagagcg agagaaatcc ctgcggccgg
     1441 ctgtggagag gctagaattg ctgctgcaga ttgcaaacaa aatacagaat ggtgctttga
     1501 actgtgaaga aaaactgaca ctagctaaga atacactgca ggctgatgct gcacacctgg
     1561 agtcaggaca gccagtgcag tgtgagtcag atgtcatcat gtacattcag gagtgtgagg
     1621 gtctcatcag gcagctgcag gtggatctcc agatcctacg ggatgaaaag tactatcagt
     1681 tagaggagct ggccttcagg gtcatgcgtc tgcaggatga actggtcacc ctgcgcttag
     1741 agtgtaccaa tctataccgg aaaggccatt tcacatcact tgaattggtt ccgccctcta
     1801 ctttaaccac tactcatctg aaagcagaac ctctgaacaa gacgactcat tcttcttcta
     1861 cctcctggtt tcgaaaacct atgacccgga ctgagcttgt agccatctca tcctctgaag
     1921 acgagggcag tctccgattc gtatatgaac tactctcttg ggtagaagag atgcagatga
     1981 aactggagcg agcagagtgg ggaaatgacc tgcccagcgt ggagctgcag tgggaaacac
     2041 agcagcacat ccacaccagt gtggaagagc tgggctcaag cgtcaaggag gccaggctgt
     2101 acgagggaaa gatgtcccag aatttccata ccagctatgt ggagactctt ggaaagttgg
     2161 agacacagta ttgtaagttg aaggagactt ctagcttccg aatgaggcac cttcagagcc
     2221 tacacaaatt tgtttccaaa gccacagctg aactgatctg gctgaatggg aaggaggaag
     2281 aagagctagc atgtgattgg agtgacagta atcccaatat ctcagccaag aaagcctact
     2341 tctctgagtt gacaatggag ctggaaggga aacaagatgt atttcgttct ctacaagata
     2401 cagcagaact gttgtcactt gagaaccacc ctgctaagca aactgtggag gcatatagtg
     2461 ctgccgtcca gtcccagttg cagtggatga agcagctgtg cctatgtgtt gaacaacata
     2521 taaaagagaa tgcagcttac ttccagttct tcagcgatgc tcgagacctg gagtcatttc
     2581 tgagaaacct acaagactcc atcaaacgaa aatatacctg cgaccacaac accagtctgt
     2641 cccgccttga ggatctgcta caggactcca tggatgaaaa ggagcagctt atacagtcca
     2701 agagttccgt tgccagtctt gttgggagat caaaaaccat tgttcagcta aagccacgca
     2761 atccagacca tgtgttgaag agcactttat ctgtgaaggc catctgtgac taccgacaga
     2821 ttgagatcac tatttgcaaa aatgatgaat gtgtgctgga agataattct cagcggacca
     2881 aatggaaggt gatcagtcct acagggaacg aggccatggt gccgtcagtc tgcctgctca
     2941 ttcccccacc aaatacggag gccattgacg tggccagcag ggtggaacag tcttaccaga
     3001 aggtgatggc cctttggcac cagctacaca ttaacaccaa aagccttatc tcctggaact
     3061 acttgcggaa ggatattgat gccgtacaga cctggaactt agaaaagctt cgttcctcag
     3121 ccccaggaga gtgccatcag gttatgaaga acctccaggc acactatgaa gactttctcc
     3181 aggacagtca tgactctgct ctcttttctg tggccgatcg cttgcgaata gaggaggagg
     3241 tggaagcttg taaaacccac ttccagcagc tgatggaatc aatggagaat gaggacaaag
     3301 aagagacttt ggcaaaggta tacatctcag agctgaagaa tatccgactt cgcctggagg
     3361 aatgtgagca gaggctgctc aaacaaattc agtcttcagc cagctctaag actgacagag
     3421 atgccaggca ggacgtcgca ttgaggattg cagagcagga gcacgtgcag gaggatttga
     3481 agcatttgag atctgacctg gatgctgttt ctgtgaaatg caccaccttt ctccagcagt
     3541 ctccatcagg ctcgagtgcc acaactctgc gctccgagct gaacctaatg gtcgagaaga
     3601 tggaccatgt ctatggtctg tctattgtct gtctgaataa gttaaagaca attgatgtta
     3661 tagtacgcag catacaggat gctgaactgt tggtcaaagg ttatgagatc aagctgagtc
     3721 aagaagaagc ggtgccagca gacctctcag ctctggagtc ccatcgaacc acattacagc
     3781 actggcttag tgatgtgaaa gacaagaatt cagtattctc agtcctggat gaggaaatct
     3841 ctaaggccaa ggcagtggca gaacagctcc atcaccgagc agcagagccg aacttggatt
     3901 tggagcgtta tcaggagaaa ggctcgcagc ttcaggagcg atggcaccgt gtcattgccc
     3961 agctggagac ccggcagtcg gaggtagaaa gtatccagga agttctgaga gattaccgag
     4021 cctgccatgg gactctcatc aagtggattg aggaaaccac tgcccagcag gaaatgatga
     4081 agccgggcca ggcagaggat agcagagtgc tgtctgagca gcttagtcag cagacggaac
     4141 tgtttgctga gattgagaga aatcagacaa aactggacca atgtcaaaaa ctttcccagc
     4201 agtactccac tactgtaaag gactatgagt tgcagcttat gacgtacaag gccttcgtgg
     4261 agtcacagca gaaatctccg ggcaagcgcc gtcgcatgat ttcctcttca gatgccatca
     4321 cacaggagtt catggacttg aggactcgat acacagcttt ggtgacatta acgactcagc
     4381 atgtaaaata tatcagtgat gctctccggc ggttggaaga agaagagaaa gtggtagaag
     4441 aggaaaaaca agaacatgtg gagaaggtta aagacctttt gggttgggtg tctactctgg
     4501 cgagaaatac acaaggaaca actacctcat ctcgcactag tgcatccaca gacattgaga
     4561 aggccatttt ggaacagcag gttctggcag aagagctgac aaccaagaaa gaacaagttt
     4621 ctgaggccat taaaacgtca caaatcttct tagccaagca tggtcataag ctttcagaaa
     4681 gagagaagga acagatctct gagcagttgt gtgccttgaa caagacttac catgatcttt
     4741 gtgatggttc tgcaaaccaa ctccagcagc tccagagcga gctggctcag cagacagaac
     4801 aaaagggttg cagagcagtt gctggggtga ttgacctagg cacagtggag atattcccca
     4861 tcttcagagc catgcaaaag ggcctcattg accaagacac aggccttgtg ctcctggaat
     4921 cccaggttat catgtctggc ctcattgctc ctgagaacag tgaaaagctc tctttggaag
     4981 agggcctcac cagaaatctc attagccttc caatgtacca acacctccta ggactaaggg
     5041 attctctgtc tttaataagt agtcttacag ggacccaagg ctccctttct gtggtggaag
     5101 caattgaaaa gaaaatagtc agtgagagat ttggactgaa agtcttagaa gttcacctgg
     5161 caactggagg tttcagtctc ccaccaagtg agaactatat taatctggaa gaagcttttc
     5221 atcaaggctt cattgcatca tggcttcatt cagaattaca gtctcacctg agaacatcca
     5281 agaatttgat agaccccaac acagccgaaa aagttggctt gctggaactg atgcagcgat
     5341 gtatcagcca tcaagagtca gggttaaaat tgttgcctgt caagcagttg gcagggggaa
     5401 tggttagctt gaaatcaggt gggaaagtta gcattttccg tgctgttcag gaagggctga
     5461 tagataggca ggtcactgtc cggttactgg aagctcagct gtttgctggt ggcatagtgg
     5521 atccaagaac aggacacaga cttacagcgg aagaggctgt gagacataat ttgattgacc
     5581 aagatatggc ctgtgctatt cttataaggc agcttcagac aggaggcatc attgacaccg
     5641 ccacaggaga aagaatgact attgacgaag cagtgaccaa taatctagta gctgctaaga
     5701 ttgctcttgt aattctggaa tccctctggt catttatggg gttactgttg cctgaatctg
     5761 gagagatcct cccaattaca gatgctctag aacaaggtat tgtgtctaat gaattagcac
     5821 ataaaatcct ccataaccga cagcaaattg aggctctttt tctaccaaca atcacagagg
     5881 tttggtcctg ggaaaaagca acagagagtg gtatcctaga taaagatctt gccaataact
     5941 taaggtcagt ctgtatccct gacatgaggc cccacataca actagcagac tctgcagagc
     6001 aaagcaaagt aggcgttgct gctgggaaac cacctctgtc gtgccaaaga gagggaagaa
     6061 ccagccgtga agagaagctg ctgtttcagc tgatgactca cagctacatt aatgcacaca
     6121 ctggacagag gctgcttcta ctggatcaag agctggtgga gatgctaaca tccagagatg
     6181 agtatcaagt aggtcttcca gaagtatttg aaattcagcc tcaaagactc gacacttcta
     6241 aggatttaca agaattggat cctgggacta tctcccaaat ttccagtgct aggaagccct
     6301 gtgaatccca gtttccttct cagagcaagg gctatcccag tcaggaaaac tgtactcaag
     6361 caaaaggtga gaggtctgtc ataggaagag agtgctcttc tgcagagagt cctgaaaggg
     6421 agctgtttgt gggagaacaa ggagccatta ctgaaaatgt tggcagtttg aaggtcatca
     6481 ataaagtcaa attagagcta caaagtccat tgttaggaag tagaaaggaa gagcaaacag
     6541 aaatgtttag cgaggaaaat gtcagcagtg atcccctcct tgtagaatgt cctgagggat
     6601 ctgaagatat gtccttggtg cttgacaagg acctttctac tgagaagtca aaatgccaag
     6661 ctcccacaaa gtcttcattt acacgtcaca aagaacaagt gaagactgtc aaagctgacc
     6721 atattccaag tgaaactgga ataccactca caaagtctca aaataaaact tcacaagttc
     6781 aggtagatgc ttctgtaagt ttgaaatcag aatttaagtc agaatacgat gagaaagagt
     6841 taaatgaaac acttttggtt aagggtagcc acaaacaaag ccaagaagga cagagtgttc
     6901 cagatggtca gatggtggtt ttagaaaagg ctgatacaga agataatggt gatgagcctt
     6961 ccttgttgtg tagttctcct tttgaagatg ctaccttaag tacattatct gcacagctac
     7021 aggatggtgg tatctttcat gaagaaacag gtcagaaact cttactaaat gaagcaatag
     7081 cccaaggcct tgtgtctagc catactgctg tgaaacttat ggggaaattg aacatgtttc
     7141 ggggcttctt cgactcccag acatgtgaat ctttgacaac tgaagaagtc attgacgaag
     7201 gtctaatgga cgagaaatta ttatgtaatg tccttatgtc agacaaagct ataagtggta
     7261 tcttagaccc taggacccac tcactgtgct ctgtacagga ggctgtagca gctggacttc
     7321 ttgacaagga gacagccaca agaattttag agggacaggt gataactggt ggaattgttg
     7381 acctgaaacg aggcaaaagg ctttcagtaa ctttggcctc aaatcttggt ttggtagaca
     7441 ctactgacca gacagaactt atcaatctgg aaaaggctac caaaggcaga ggtgctgaaa
     7501 aggcggttaa agagagatta attgggctac agatggaaac aacaggactt ctggaccctg
     7561 aaagtaaagc accattaaca gtcttgcagt ccattgatag aggtcttata gagagagaag
     7621 aagctattta tcagttgact aagcaagtac ttgatggtgg tatcattcat catatatctg
     7681 gcttgagact ctctgttgat aatgccttta aacatggcat gattggtgaa gatgtagcca
     7741 ggcagctcag aaaagttgag aactttaacc accatcaatt ttttcatcct caaacaaagg
     7801 aagctctttc cttctcagaa gccataaaat tagatcttgt ttctccagac ttgaaaagag
     7861 aaatccaaga gattctggac tttagtgaaa acttggggga tctcatttat ggccagaaat
     7921 tgacctcggt aaaagctaac aaagaagaat ccttagctaa taaaacagca ttgccttcga
     7981 gagtgataca tggggttata gatcctgaga gctgcacaac aattccctac tcagaattgg
     8041 taaagaaatg taggattgac attgaatctg gatggagata tctcgaagta attccactct
     8101 ctgatattaa agatgagatg agcaacaaag tgctaacacc atctgaagca attcagcgtg
     8161 gaaaagtaga ctttgggtct atgttgaagg ttttggaagc tcaggcgaac actggtggaa
     8221 tcatagatat ggccacagga aaaagagtga cattggcatc agctttagaa cagaaactca
     8281 tagatgaaaa catggccagg attattgcat cccatcaagt gttaactgga ggaattattg
     8341 atatatataa tgatcaaaga gtgactttaa atgatgctgt tgagaaaagg ttgattagcc
     8401 ctgaactggc aactatgatc caagcagata ccttaggaaa gcaaggtggg actggagtat
     8461 gtgaattaaa gggtgaattt ctaagaaatg agtttaggaa ggccaccagg gagagttatg
     8521 ataaagagaa acatgaggga gtgttacaag ttggaagtca gtgtgctcaa gaaaaggcta
     8581 acgtaagggt ttcttatggg gtaaaggtag gaaagggcaa gaagatttca gtagagatgg
     8641 aaggccagcg tcaagacgag gagaaggctt cttcagacaa tgaagtatct gccagcatcg
     8701 taagtcctgg tggtcttgag ggtgaatcta cacaccaagt tttggtgacg catccctgct
     8761 caggatcttc tgatttgaaa ctcatagagg aagccaggag tccagaggta gagcaggagg
     8821 aagcagtagc acgaatgaag atgactcctc acgtaaatcg gtcaacccca ggcctggatg
     8881 ctggagaagc aagagactgt ccagggagag tgggttcgaa aggacaagaa tctaagcatg
     8941 aaccagcagg caaactgtcg agtgtgcagg cagcgaatgt ggaagttggt aggagaggaa
     9001 ggagagagac gggtggagag gaaagagtcc aaacaaacaa agtggcagca ggtccttctg
     9061 aggaagagtt ggaccaggaa gttacaattg gtgacgaaca tggctccttt gtaaagagcc
     9121 agcctatgaa gacaattgga aatgacaggg gaaaagaagg tggtagagaa aaggactttt
     9181 ctcttgtttg taaaaccgaa ggcttccctt cccagatgac attcaaagat gcttccctag
     9241 aaaatcaaaa tgctttgatg ttcttcagcg aaggggaaac gaaaactgtc aacctctgct
     9301 cgattttaaa acaaagagaa aagttatctc aagaaactgc tagtattgtc cagaaggaac
     9361 cattctcttc tgagattcca agacctgaaa gactgaactc ccaggaatca gatggagaat
     9421 cccatatttc tgacatgccc tgcatttcca aaggtcccat ggctgcccaa attaccacaa
     9481 gacaggagac tactgatgaa caagacctga gtattacatc taagactgca gagaccaaag
     9541 ataggatttt cccatccaaa aattataaag aaaagttact tcaagaaata cctatggact
     9601 caacaagagc ccataaactg aaagaaagca cagtttccac tctagacacg gaaggactcg
     9661 gttatctaga ttcctcagat ataaaggctc ttcatgagga tagcagagca gatcgtgagt
     9721 ttagtggaca tcagaaatca aaaataacaa caacccagga agtaaaattt ctagaagtgg
     9781 taaatcccct agttagagac gcagaaggtc acagagggtc ctctaaggac agagtggctc
     9841 aaagaggacc cagaaccttg gcatctcttc ttccggagaa actgcccgca gggacagcac
     9901 agagtgagaa tacaaagcag catgacacag tcattattgc caccactccc gaaatgaggg
     9961 aggagatgcc actgtccctg ccatgttctc cattgaaggt ggatgagcag atacctaagg
    10021 agaagcacaa agagctccct ggagatgagc gagcctcctg catggctaca cctagtggga
    10081 aggggagtga gggtgtaaag ccagcacctt gcagagcaac tcagaatgtg tttacccgga
    10141 gactttgttt agaacatgat gagaaattgg tctcctatct gtccctgtta cgggacattg
    10201 aaatgagaac caaacagatt caacctttgg aacttagtgt ggcagagctg caagatctgc
    10261 tgggtcaggc caaggtatta gacagggaat taaaagatct gtctaccgtg gtaagtcagg
    10321 aattggaatg tgtggatcag attgttatca gtcagccaca agaagttcct gctcagctgt
    10381 tgaaggcgtt agagaaggat gccaagaatc ttcagaagtc tctaggctct gttcgtgact
    10441 cctggagctc cagatccctc catctgcaca atgcagtgga agtgaaaaag accacagtgt
    10501 taaattggca caaggagcta gaaggcaaac ttcaagatct gaaagcctgg gttgacagaa
    10561 ccagtcttac tctgcatagc aagggatgtg acactcaaac tgatgctgac agcctgagtc
    10621 ccactctcca gggatatgag gatatgaaac agtctgtagc cgaaaggaag tctcagctgg
    10681 atgccctggc tttggatact cagctcttta tttctgagca cccacagggc ttgtctcttc
    10741 agcagaatca gcaaatgctg cagtttctga gtgaattaca gacgtctttc cagggccttg
    10801 tggaacacac tgcagctcag aaggatgtgg tgcagggcca tctccagcaa gtccagcaag
    10861 aagttcaggt caagactctg cagaagcaac aagacacgtg tcataagaag ctggaggatc
    10921 tccgcagctg ggtcagacag gcagaaaggg cactggagag gcaccggggc agggcctctc
    10981 aacaagagct ttctgctctg cagcagaacc aaagtgactt gaaggatttg caaggtgaca
    11041 ttcagaatca ctccacctca tttgccactg ctgtcaaaga cattgaaggg ttcctagaag
    11101 agaaccagaa caagctgagc cctcaggagc tgacagctct tcgagaaaaa ctttatcaag
    11161 caaaggagca atatgagggt ctccaggatc gcacacggga ggctcagaag gagctggagg
    11221 aagcagtgac gtcagcctta cagcaggaga cagagaagag taaagcagcg acagagctgg
    11281 cagagaacag aaggaagatc gacgctctct tggactgggt gacttctgtg gggtcatctg
    11341 atagacagcc acagactagc cttccaggaa cggagcagtt ctctggagct tgcctggaaa
    11401 aacaaacctt agatgcaaca gatggttgtg tggatgtaaa ccaagtacca gagaaactgg
    11461 acaggcagta tgagttaatg aaggcacgtc accaagaatt gctgtctcag cagcagaatt
    11521 tcattgtggc tacccagtca gctcagtcct tcctggacca acacagtcac aatcttacac
    11581 ctgaggagcg acagatgctt caggagaagc taggtgagct taaggagcaa tatgcagctt
    11641 ccctggccca gtcagaggca aagctgaggc agacgcagac tctacgagat gaactgcaga
    11701 agttcctgca agaccacagg gaatttgaaa actggctaga acgatctgag aatgaactgg
    11761 atggtatgca tacgggaggc agcagccctg aagctctgaa ctccttgctt aagcggcaag
    11821 gaagcttctc agaggatgtc atttcccaca aaggagactt gagatttgtg actatctcag
    11881 gacagaaagt cttagaaaca gaaaacaatt ttgaggaagg ccaggagccg tcacccacca
    11941 gaaacttagt gaatgaaaaa ctgaaggatg caacagaaag atacaccact ctccattcta
    12001 agtgtacacg attgggctct cacctgaaca tgctgctagg ccagtatcag caattccaga
    12061 gcagcgctga cagcctgcag gcctggatgt tgacttgtga ggccagtgtg gagaagctcc
    12121 tctcagatac tgttgcctct gaccccggga tccttcagca acagctcgca accacaaagc
    12181 agttacagga agaattggct gaacaccaag tacctgtaga aaagcttcaa aaagcagctc
    12241 atgacctaat ggacattgaa ggagagccat ccctggactg tacgcctatt cgagaaacta
    12301 cagagtccat attcagccgc ttccagagcc tctcttgtag cttagctgag cggtctgctt
    12361 tgctgcagaa ggcaattgct cagtctcaga gtgttcagga aagtatggag agcctcctgc
    12421 agtccatgaa ggaagttgag caaaacctgg aaggggagca ggtggcagca ctctcatcag
    12481 gactcatcca agaggccttg gccaacaaca tgaaactaaa gcaagacatt gctaggcaaa
    12541 aaagcagctt ggaagccacc cgtgagatgg tcactcgatt catggagacc gctgacggca
    12601 actcggccgc agtgctgcag gacagactgg cagagctgag ccagcgattc catcggctgc
    12661 agctccagca gcaagaaaag gaaagcggcc tgaagaagct cctgccccag gccgagacat
    12721 tcgagcagct ctccagcaag ctgcagcagt tcgtggaaca caaaaaccga ctgctggcct
    12781 cagggaacca gccagatcaa gacattgcac atttctccca gcacatccag gaactcacat
    12841 tggaaatgga agaccaaaag gaaaacctag gtactctcga gcacctagtt actgcgctgg
    12901 gctcttgtgg ctttgcactg gatctgtctc agcaccaaga aaagatacag aaccttaaga
    12961 aggattttac agagttgcag aagacagttc aagaaagaga gaaagatgca tcaaattgcc
    13021 aggaacaatt ggatgaattc cggaaactga ttagaacctt ccagaaatgg ctgaaagaaa
    13081 ctgaaggaaa cgttccacct gcagagactt tcgtgagtgc taaggaatta gagaagcaga
    13141 ttgaacactt gaagggtctc ctagatgact gggcaggtaa aggagtgctg gtggaggaga
    13201 tcaacaccaa gggcactgcc ttagaaagtc tcatcatgga catcacagcg cctgattccc
    13261 aggctaagac aggttccgta ctaccctctg taggaagctc tgtaggcagt gtaaacggat
    13321 accacacctg caaagatctt acagagattc aatgtgacat gtctgatgta aattccaagt
    13381 atgataaact gggagacgcg ctgcgggaac gccaggaaag ccttcagact gtcctcagca
    13441 gaatggagga ggtccagaag gaggcgagct ctgtattaca gtggttagaa tcaaaagaag
    13501 aagttctgaa aggcatggat gcctctttgt ctccaaccaa gacagaaaca gtaaaagccc
    13561 aagcagaatc taataaggct ttcctggctg aattggagca gaattccccc aaaatccaga
    13621 aagtaaagga agccctggct ggattactgg aagcatatcc caattcacaa gaagcagaaa
    13681 actggaggaa aatgcaagag gacctcaatt cccgatggga aaaggccacc gaggttactg
    13741 tggctcgcca aaagcagcta gaggaatctg caagccatct ggcctgcttc caggctgcag
    13801 agtcccagct ccgcccttgg ctgatggaaa aggagctgat gatgggagtt cttggtcccc
    13861 tgtctattga ccccaacatg ttgaatgccc agaagcagca ggtccagttt atgctgaagg
    13921 aatttgaagc acgaaggcag cagcatgagc agctgactga ggcagctcag ggcatcctca
    13981 cgggtcctgg agatgtgtct ccctctgcca gccaagtaca caaagatctg caaagcatca
    14041 gtcagaagtg ggttgagctc accgacaagc ttaactcccg ttccacccaa attgaccaag
    14101 ctattgttaa aagtacccaa taccaagact tgctccagga cttatcagaa aaggtgaagg
    14161 cagttggaca gcgactgagt ggccagtcag ccatcagcac ccaacctgat gctgtgaagc
    14221 agcagctaga ggagaccagt gagattcggt ctgacttggg acaactagac gatgagatga
    14281 aggaggctca gacgctgtgc caagaactct cactgctcat tggcgagcag tacctcaagg
    14341 atgagctgaa gaaacgtttg gagacagttg ccctgccact ccaaggctta gaagacctcg
    14401 cagctgaccg catgaacaga ctccaggcag ctcttgccag cacccagcaa ttccagcaaa
    14461 tgtttgatga gctgaggacc tggttagatg aaaaacaaag tcagcaagca aaaaactgcc
    14521 caatttctgc aaaattggaa aggctccagt ctcagctaca agagaatgaa gagtttcaga
    14581 agaaccttaa tcagcacagt ggttcctatg aggtgatcgt ggctgagggg gagtctctgc
    14641 tgctttctgt gccccctgga gaagagaaaa agactttaca aaaccaactg gttgaactca
    14701 aaagccattg ggaagatctt aataaaaaaa ctgtagacag acagtctagg ctcaaggact
    14761 gtatgcagaa agctcagaag tatcagtggc atgtggaaga ccttgtgccc tggataaaag
    14821 attgcaagtc caagatgtct gagttgcagg ttaccctgga tccagtacaa ctagagtcta
    14881 gcctcttaag gtcaaaggct atgctgaatg aggcagagaa gcgccgctcc ctgctggaaa
    14941 tactgaatag tgctgctgac attcttatca attcttcaga aattgatgaa gatgagatcc
    15001 gagatgagaa ggctggactc aaccagaaca tggatgccat tactgaggag ctgcaggcca
    15061 aaacaggctc tctagaagaa atgactcaga ggctcaagga gttccaggaa agctttaaga
    15121 acattgaaaa gaaagttgaa ggagccaaac accagcttga aatctttgat gccttgggct
    15181 ctcaagcctg tagtaacaag aatctggaga agctaaaggc tcagcgagaa gtgctgcagg
    15241 ccttggaccc tcaggtagac tatctgcggg acttcactcg gggactcgta gaggatgccc
    15301 cagatggatc tgatgcttcc ccactcgtgc accaagctga gcttgcacag caggagttct
    15361 tagaagtgaa gcaaagagtg aacagtagct gcctgaccat ggagaacaag ctagagggga
    15421 tcgggcagtt tcactgtcga gtccgagaaa tgttttctca attggctgac ctggatgatg
    15481 agctagatgg catgggagcc attggtagag acacagatag cctccagtca caaattgagg
    15541 acatacggct attccttaac aaaatccaag ccctcaggct tgacatagag gactctgaag
    15601 cagagtgtcg aaaaatgttg gaggaagagg ggactttaga cttactgggt ctcaagaggg
    15661 agctagaagc ccttaacaag cagtgtggta aactgacaga gcgagggaaa gctcgccagg
    15721 agcagctaga gctgacgctg ggccgagtag aggacttcta cagtaaactg aaagcgctca
    15781 atgatgctgc cactgctgca gaggagggag aagctcttca gtggattgtg gggactgaag
    15841 tcgatgtcat caaccagcaa ctagcagatt tcaaaatgtt tcagaaagaa caagtggatc
    15901 ctcttcaggt gaaattgcag caggtgaatg gacttggcca gggattaatt cagagtgcgg
    15961 gaaaaacctg tgatgtgcag ggtttagaac atgacatgga agaggtcaat actcgatgga
    16021 atacactgaa taaaaaggtt gcacaaagaa ttgcacaact gcaggaggct ttgttacatt
    16081 gtgggaaatt tcaagatgcc ttagagccat tgctcagctg gttgacagac accgaggagc
    16141 tcatagccaa tcagaagcct ccatctgccg agtataaagt ggtgaaagcc cagatccaag
    16201 aacagaagtt gctccagcga ctcctagatg atcgcaaggc cacagtggat atgcttcaag
    16261 cagaaggagg cagaatagcc caggctgctg aactggctga tagagagaaa atcactgggc
    16321 agctggaaag ccttgaatgt agatggactg agctcctcag caaggcagca gccaggcaaa
    16381 agcagctgga ggatatcttg gttctggcta aacaattcca cgagacagct gagcctattt
    16441 ctgacttcct atctgtcaca gagaaaaagc ttgctaactc ggaacctgtt ggcactcaaa
    16501 ctgccaaaat acaccagcag attattcgtc acaaggcttt aaatgaagag attattaata
    16561 gaaagaagaa tgtagatcaa gctattaaaa atggtcaggc tcttctaaaa caaactacag
    16621 gtgaggaggt gttacttatc caggagaagc tggatggaat aaagacccgt tatgcagaca
    16681 tcactgtcac tagctccaag gccctcagaa ctttagaaca agcccggcag ctggccacca
    16741 agttccattc tacatatgag gaactgactg ggtggctgag ggaggtggag gaggagctgg
    16801 cggccagtgg aggacagtct cccacagggg agcagatacc ccagtttcag caaaggcaga
    16861 aggaactgaa gaaggaggtc atggagcaca ggctggtgtt ggacaccgtg aatgaggtga
    16921 gccatgcgct cctagagctg gtgccttgga gagccagaga aggactggat aaacttgtgt
    16981 ctgatgccaa cgagcagtac aaactggtca gtgacaccgt tggacaaagg gtagatgaaa
    17041 ttgatgctgc tattcagaga tcacaacagt acgagcaagc tgctgatgca gaactagctt
    17101 gggttgctga aacaaagcga aagctaatgg cgcttggtcc aattcgtcta gaacaagacc
    17161 agactactgc tcagctgcag gtacaaaagg ctttctccat tgacatcatt cgacacaaag
    17221 actccatgga tgagctcttc agtcaccgtg gagagatctt tagcacatgt ggggaggagc
    17281 agaaggctgt gctgcaggag aagaccgagt gcctaataca gcaatatgaa gccgttagcc
    17341 tgcttaactc agagcgctat gctcgcctag agcgagcaca ggtcttagtg aaccagtttt
    17401 gggaaacgta cgaagagctc agcccctggg ctgaggagac cctagcgttg atagcacagc
    17461 tgccgcctcc tgctgtggac catgagcagc tcagacagca gcaggaagag atgaggcaac
    17521 taagggaatc cattgctgaa cacaaacctc atattgataa gatactaaag ataggtccac
    17581 aactgaagga gctaaaccct gaagaaggga aaatggttga agaaaaatac cagaaagcag
    17641 aaaacatgta tgcccaaata aaagatgagg ttcgccaacg ggccctggct ctggatgagg
    17701 ctgtgtccca gtctgctcag tttcatgata aaattgaacc catgttggag actctggaga
    17761 atctgtcctc tcgcctgcga atgccgcccc tgatccctgc tgaagtagac aagatcagag
    17821 agtgcatcag tgacaataaa agtgccacca tggagctgga aaaactgcag ccatcctttg
    17881 aagccctgaa gcgtcgggga gaggaactca ttgggagatc acagggagca gacaaggatt
    17941 tggctgcaaa agaaatccag gacaagctgg atcaaatggt attcttttgg gaggacatta
    18001 aagcacggtc tgaagagcga gaaattaaat tccttgatgt ccttgagtta gcagagaagt
    18061 tctggtatga catggcagcc ctcctgacca ccatcaaaga cacacaggag attgtccatg
    18121 acctggaaag ccctggcatt gacccatcca tcatcaagca acaggttgaa gctgctgaga
    18181 ctattaagga ggagacagat ggtctgcacg aggagttgga gttcattaga atccttggag
    18241 cagatttgat ttttgcctgt ggggaaacgg agaagcctga agtgaagaag agcattgatg
    18301 agatgaataa tgcttgggag aacttaaata gaacttggaa agaacgacta gaaaagctcg
    18361 aggacgcgat gcaagctgct gtgcagtatc aggacacgct ccaggccatg tttgactggc
    18421 tggataacac tgtaatcaga ctctgcacca tgcccccagt gggcactgac ctcaacactg
    18481 tcaaagatca gctgaacgag atgaaggagt tcaaagtaga agtttaccaa cagcaaattg
    18541 agatggagaa actcaatcac cagggtgaat tgatgttaaa gaaagctact gatgaaactg
    18601 acagagatat tatacgagaa ccactgacag aactcaaaca cctctgggag aatctgggtg
    18661 agaagattgc acatagacag cataagctgg agggcgctct cttggccctc ggccagttcc
    18721 agcatgccct agaagagctg atgggttggc tgactcacac tgaggagctg ctggatgctc
    18781 agaggccaat aagtggagac ccaaaagtca ttgaagttga gcttgcaaag caccacgttc
    18841 taaaaaatga tgttttggct catcaagcca cagtggaaac agtcaacaaa gctggtaatg
    18901 aactccttga gtctagtgct ggagatgatg ccagcagcct aagaagccgc ctggaaacca
    18961 tgaaccagtg ctgggaatct gtgctgcaaa agacagagga gagggagcag cagttgcagt
    19021 caactctgca gcaggcccag ggtttccaca gtgaaattga agagttcctc ttagaactca
    19081 atagaatgga gagccaactt tctgcatcta aacctacagg aggactcccg gagacggcta
    19141 gagaacagct tgatgcgcac atggaactgc attcccagct gagagccaag gaggagattt
    19201 acaaccagtt gcttgacaag ggcaggctta tgctcctcag ccgtggtgat tctgggtctg
    19261 gctcaaaaac agagcagagt gtagcgctct tggaacagaa gtggcatgtg gtcagcagta
    19321 aggtggagga aagaaagtca aagctcgaag aggccctcag cctggcaaca gaattccaga
    19381 attccttgca agaatttatc aactggctta ctctagcaga gcagagttta aacattgcct
    19441 ctcctcccag cctgatttta aacactgttc tttcccagat agaagagcac aaggtttttg
    19501 ctaatgaagt aaatgctcat cgagaccaga tcattgaact ggaccaaaca gggaaccagt
    19561 tgaagtttct tagtcagaaa caggatgttg tcttgatcaa gaatttgtta gtcagtgtcc
    19621 agtctcggtg ggagaaggtt gtccagcggt ctattgaaag ggggcggtca ctggatgatg
    19681 ccaggaagcg agccaagcaa ttccatgaag cttggaaaaa gctgattgac tggctagaag
    19741 atgcggagag ccatctggac tcagaactgg agatctccaa tgacccagac aaaatcaagc
    19801 ttcagctttc caaacacaag gaatttcaga aaactcttgg tggcaaacag cctgtgtatg
    19861 acaccaccat cagaactggc agagcactaa aagaaaagac tttgcttgct gacgatgctc
    19921 agaaacttga caacttgcta ggagaagtca gagacaaatg ggacactgtc tgtggcaagt
    19981 ctgtggagcg acagcacaag ttggaagaag ccttactgtt ttcaggccaa ttcatggatg
    20041 ctttgcaggc tttagttgac tggttgtaca aggtagagcc acagttggct gaggaccagc
    20101 ctgtacacgg ggaccttgac ctcgtcatga acctcatgga tgctcataag gttttccaaa
    20161 aagaactggg aaagagaacc ggcaccgttc aggtcctgaa gcggtcaggc agagaactga
    20221 ttgagagcag cagagatgac accacatggg taaaggggca gctccaggag cttagcacac
    20281 gctgggatac agtgtgcaaa ctctctgttt ccaagcaaag ccggcttgaa caggccttaa
    20341 aacaggcaga agagtttcgg gacaccgtcc atatgctgtt ggagtggctt tctgaagcag
    20401 aacaaacact tcgctttcga ggggcccttc ctgatgatac ggaggcccta cagtctctca
    20461 ttgacaccca taaggaattc atgaagaaag tagaggaaaa acgggtagat gtgaatgcag
    20521 cagtggcgat gggagaagtc atcctggctg tctgccatcc tgattgcatc acgaccatca
    20581 agcactggat caccatcatc cgagctcgct tcgaggaggt tctgacatgg gcaaagcagc
    20641 accagcagcg cctggaaaca gctctgtcag aactggtggc taatgccgag ctcctggaag
    20701 aacttctggc gtggatccag tgggccgaga ccaccctaat ccagcgggat caggagccta
    20761 tccctcagaa catagacaga gttaaagctc ttatcaccga gcatcagtca tttatggagg
    20821 agatgacacg caaacaacct gatgtggacc gggtcaccaa gacatataag aggaagaata
    20881 tagaacccac ccatgctcct ttcatcgaga aatcccgcag tggtagcaga aagtccttga
    20941 atcaacccac acctccaccc atgccaatcc tctcacagtc tgaagcaaaa aacccacgaa
    21001 tcaaccagct ctctgcccgc tggcagcaag tatggctgtt agccctggag cgccagcgga
    21061 agctgaacga tgccttggat agactggagg agctatgccc ggaattgaag gaatttgcca
    21121 actttgactt tgatgtctgg aggaaaaagt atatgcgttg gatgaatcac aaaaagtctc
    21181 gagtcatgga tttcttccgg cgtattgaca aggaccagga tgggaaaata acacgtcagg
    21241 agtttatcga tggcatttta gcatctaagt tccctaccac caagttagag atgacagctg
    21301 tggctgacat ttttgacaga gatggggatg gctacattga ctactatgaa tttgtggctg
    21361 ccttacatcc caacaaggat gcctatcgac caacaactga tgcagataag attgaggatg
    21421 aggtgacaag acaagtggct cagtgcaagt gtgcgaaaag attccaagtg gagcagattg
    21481 gcgagaataa atatcggttc ttcctcggca atcagtttgg agattctcag cagttgcggc
    21541 tggtccgtat tctgcgcagc actgtgatgg tccgcgttgg tggaggatgg atggccctgg
    21601 atgagtttct agtgaaaaac gatccctgcc gagcacgggg cagaactaac atagaactta
    21661 gagagaaatt catcctgcca gaaggggcat ctcaggggat gactccattc cggtcacggg
    21721 gtcgaagatc caaaccatct tcccgggcag cttctcccac ccgctccagc tcaagtgcta
    21781 gtcagagtaa ccacagctgt acgtccatgc cttcttctcc agccacccca gccagtggga
    21841 ccaaggttat ttcatcaaca ggcagcaagc tgaaaagacc aacaccaact tttcattcta
    21901 gccgaacatc ccttgctggt gacaccagca atagttcttc cccagcttcc acaggtgcca
    21961 aaactaatcg ggcagaccct aagaagtctg ccagccgtcc cgggagtcgg gccgggagcc
    22021 gggccgggag ccgagccagc agccgtcgag gaagtgacgc ctctgacttt gaccttctag
    22081 agacacagtc agcgtgttca gacacttctg agagcagtgc cgcagggggg cagggcagct
    22141 ccagaagagg gctcaccaaa ccctccaaaa tcccaaccat gtctaagaag accaccactg
    22201 cctcccccag gactccatgt cccaagcgat aacactgtac aagcagccca caccactctc
    22261 cactttgaat cctgcttcat acgttgggtg tatatttatt ctgaacggga gaagttatat
    22321 tgttaaaatt gtaaaagaat aattgtgtta tgaagctgcc ttattttttt tcctttttgt
    22381 aagttactat tttcatgtga atatttatgt agataaaatt tgactcctgg taaccctgta
    22441 acagacaggg cccagagatg aaatatttga ggaaaacaaa aggtcaagat gcagatgtat
    22501 taaaaagaaa agcctcggaa tagggtttcc tgtggggcag ggttataaac ctgctttatc
    22561 ttttaggatt attcctaaat gcatcttctt tataaacttg acttgctata tcagcaagat
    22621 aaattatatt aaaaaaaata agaattctgc aatgtttaag gaactcttct ttctaaatca
    22681 cagacacctc aactagcaag agttaaggag aggacactta aggttgcatt tccattgttt
    22741 tactgctgtg taattttagc tgaagagaca gaacctcatc tagatagcct ttgcacatga
    22801 tagagcaaag agtccattgc aatactgtct taaagtaatg tctcagtacg gggtgttaaa
    22861 gggcacatag ctgctaggat tcaggggtaa aaggaaactt caaaacattg gggttttaaa
    22921 ctgatttgta acaaactgtc caacccagcc ctcaatgact cctgtgctca ccaggcccca
    22981 ggcccctggt gaggggactc cttggaggca ctgtgaatta cagatttgtt tatctgcttt
    23041 tttttttttt ctatttattt aaatggtcga tcaacctccc ataaactgag ggatgacttc
    23101 catgcaccca ttttgaaatg tggacctaag acaaacactg actcatcctt aacggagttc
    23161 accagcacac cagtccgttt gcttccgtct cctgtgtgtg taataaagtc agctgaccaa
    23221 gtaaccacag aggggctgtc tggggctccc gtttttttag ctgctgttcc ttgtcagctc
    23281 tgaccatgtt gctgtgtgat tatctcaatt ggttttaatt gaggcagaaa ctgaagctct
    23341 accaatgaac tgtttaaaaa caagacacac ttttgtatta aaattgcttg cagtaacaaa
    23401 tgttttgtaa ttcctggctt tattctgaac cactacttta tatttaaatg ttaccgctaa
    23461 ggtatgaaaa tgttgtagta cctaaataca tcattcaaca agagttttct tgatggaaaa
    23521 aaaa
//
