LOCUS       NM_001135833             801 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus lysozyme-like 6 (Lyzl6), mRNA.
ACCESSION   NM_001135833 XM_213497
VERSION     NM_001135833.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 801)
  AUTHORS   Huang,P., Li,W., Yang,Z., Zhang,N., Xu,Y., Bao,J., Jiang,D. and
            Dong,X.
  TITLE     LYZL6, an acidic, bacteriolytic, human sperm-related protein, plays
            a role in fertilization
  JOURNAL   PLoS One 12 (2), e0171452 (2017)
   PUBMED   28182716
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 801)
  AUTHORS   Narmadha,G. and Yenugu,S.
  TITLE     Immunization against lysozyme-like proteins affect sperm function
            and fertility in the rat
  JOURNAL   J Reprod Immunol 118, 100-108 (2016)
   PUBMED   27821286
  REMARK    GeneRIF: this study indicates a role for LYZL6 protein in sperm
            function
REFERENCE   3  (bases 1 to 801)
  AUTHORS   Wei,J., Li,S.J., Shi,H., Wang,H.Y., Rong,C.T., Zhu,P., Jin,S.H.,
            Liu,J. and Li,J.Y.
  TITLE     Characterisation of Lyzls in mice and antibacterial properties of
            human LYZL6
  JOURNAL   Asian J Androl 15 (6), 824-830 (2013)
   PUBMED   24013621
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Oct 15, 2008 this sequence version replaced XM_213497.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360181.220664.1,
                                           SRR26643293.66613.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                JAXUCZ010000010.1  89049178-89049210   c
            34-219              JAXUCZ010000010.1  89048659-89048844   c
            220-378             JAXUCZ010000010.1  89047061-89047219   c
            379-457             JAXUCZ010000010.1  89045940-89046018   c
            458-801             JAXUCZ010000010.1  89044375-89044718   c
FEATURES             Location/Qualifiers
     source          1..801
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.1"
     gene            1..801
                     /gene="Lyzl6"
                     /gene_synonym="Lyzb; RGD1306968"
                     /note="lysozyme-like 6"
                     /db_xref="GeneID:287751"
                     /db_xref="RGD:1306968"
     exon            1..33
                     /gene="Lyzl6"
                     /gene_synonym="Lyzb; RGD1306968"
                     /inference="alignment:Splign:2.1.0"
     exon            34..219
                     /gene="Lyzl6"
                     /gene_synonym="Lyzb; RGD1306968"
                     /inference="alignment:Splign:2.1.0"
     CDS             78..527
                     /gene="Lyzl6"
                     /gene_synonym="Lyzb; RGD1306968"
                     /EC_number="3.2.1.17"
                     /note="lysozyme-like protein 6; lysozyme b"
                     /codon_start=1
                     /product="lysozyme-like protein 6 precursor"
                     /protein_id="NP_001129305.2"
                     /db_xref="GeneID:287751"
                     /db_xref="RGD:1306968"
                     /translation="MMMRVLFICVVSCLLVVNDGSIINRCTLARILYQEDLDGFEGYS
                     LPHWLCLAFVESKFNISKVTENADGTFDYGIFQINSRYWCNDYQSHSENFCRLDCEEL
                     LNPNLIPSIHCAKMIVSGSGGMKNWVDWRLHCLGRPLSYWLTGCRLV"
     exon            220..378
                     /gene="Lyzl6"
                     /gene_synonym="Lyzb; RGD1306968"
                     /inference="alignment:Splign:2.1.0"
     exon            379..457
                     /gene="Lyzl6"
                     /gene_synonym="Lyzb; RGD1306968"
                     /inference="alignment:Splign:2.1.0"
     exon            458..801
                     /gene="Lyzl6"
                     /gene_synonym="Lyzb; RGD1306968"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aatggatgaa gccctgttga gttagacttt cagattcccc aggctctcag agaccggctg
       61 gtaccccgtc tccttggatg atgatgaggg tgctgtttat ctgtgtggtg agctgccttc
      121 tggtcgtgaa tgatggcagc atcatcaatc gctgtacctt ggccaggatt ctgtatcaag
      181 aggacttgga tgggtttgag ggctactccc tgcctcactg gctgtgcttg gcttttgtgg
      241 agagcaaatt caacatatca aaggtgactg agaatgcaga tggtaccttt gactatggaa
      301 tcttccagat caatagccgt tactggtgca atgactacca gagtcattca gagaacttct
      361 gccgcctgga ctgtgaagaa ctactgaatc ccaacctcat tccatccatc cactgtgcaa
      421 aaatgattgt gtctggatct ggagggatga agaactgggt agattggagg ttgcactgtt
      481 taggacggcc actctcctac tggctgacgg gatgccgtct ggtatgaacc agggtgcaga
      541 cttactgggg agtcactcca ggacctctgt actccttggc cattcttcac tatttcatcg
      601 tcttgccttc acctgttact ttctcctctt cccactcgca agtaaaactg accagagtcc
      661 cagggggaaa cgccttacct cggctccctg cttgtgttca cccaggcccg gttcctttgt
      721 tcctatcatt tgcaaaccaa gaaggtgtca tataaataca attgcatttt tcaaaattta
      781 ttaaagcaca ccatgggcaa a
//
