LOCUS       NM_001246183             993 bp    mRNA    linear   ROD 07-DEC-2024
DEFINITION  Rattus norvegicus lysozyme-like 4 (Lyzl4), mRNA.
ACCESSION   NM_001246183 XM_001078029 XM_006244123 XM_343507
VERSION     NM_001246183.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 993)
  AUTHORS   Narmadha,G. and Yenugu,S.
  TITLE     Immunization against lysozyme-like proteins affect sperm function
            and fertility in the rat
  JOURNAL   J Reprod Immunol 118, 100-108 (2016)
   PUBMED   27821286
  REMARK    GeneRIF: this study indicates a role for LYZL4 protein in sperm
            function
REFERENCE   2  (bases 1 to 993)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   3  (bases 1 to 993)
  AUTHORS   Sun,R., Shen,R., Li,J., Xu,G., Chi,J., Li,L., Ren,J., Wang,Z. and
            Fei,J.
  TITLE     Lyzl4, a novel mouse sperm-related protein, is involved in
            fertilization
  JOURNAL   Acta Biochim Biophys Sin (Shanghai) 43 (5), 346-353 (2011)
   PUBMED   21444326
REFERENCE   4  (bases 1 to 993)
  AUTHORS   Narmadha,G., Muneswararao,K., Rajesh,A. and Yenugu,S.
  TITLE     Characterization of a novel lysozyme-like 4 gene in the rat
  JOURNAL   PLoS One 6 (11), e27659 (2011)
   PUBMED   22110709
  REMARK    GeneRIF: the characterization of Lyzl genes in the rat
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On or before Mar 3, 2022 this sequence version replaced
            XM_006244123.4, NM_001246183.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.48344.1,
                                           SRR26360181.1330680.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMEA5760434
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-269               JAXUCZ010000008.1  130132604-130132872 c
            270-519             JAXUCZ010000008.1  130129963-130130212 c
            520-669             JAXUCZ010000008.1  130129712-130129861 c
            670-748             JAXUCZ010000008.1  130128509-130128587 c
            749-993             JAXUCZ010000008.1  130125642-130125886 c
FEATURES             Location/Qualifiers
     source          1..993
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..993
                     /gene="Lyzl4"
                     /gene_synonym="Lyza; RGD1308401"
                     /note="lysozyme-like 4"
                     /db_xref="GeneID:363168"
                     /db_xref="RGD:1308401"
     exon            1..269
                     /gene="Lyzl4"
                     /gene_synonym="Lyza; RGD1308401"
                     /inference="alignment:Splign:2.1.0"
     exon            270..519
                     /gene="Lyzl4"
                     /gene_synonym="Lyza; RGD1308401"
                     /inference="alignment:Splign:2.1.0"
     CDS             381..818
                     /gene="Lyzl4"
                     /gene_synonym="Lyza; RGD1308401"
                     /note="lysozyme-like protein 4; lysozyme a; lysozyme-4"
                     /codon_start=1
                     /product="lysozyme-like protein 4 precursor"
                     /protein_id="NP_001233112.1"
                     /db_xref="GeneID:363168"
                     /db_xref="RGD:1308401"
                     /translation="MQLYLVLLLISYLLTPIGASILGRCVVAKKLYDGGLNYFEGYSL
                     ENWVCLAYFESKFNPSAVYENSRDGSTGFGLFQIRDNEWCDHGKNLCSVSCTALLNPN
                     LKDTIECAKKIVKGKQGMGAWPVWSRNCQLSDILDRWLDGCEL"
     exon            520..669
                     /gene="Lyzl4"
                     /gene_synonym="Lyza; RGD1308401"
                     /inference="alignment:Splign:2.1.0"
     exon            670..748
                     /gene="Lyzl4"
                     /gene_synonym="Lyza; RGD1308401"
                     /inference="alignment:Splign:2.1.0"
     exon            749..993
                     /gene="Lyzl4"
                     /gene_synonym="Lyza; RGD1308401"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggttctaga agagtttctc atggagcagg atcaatggtg tagaaactct tgggtgaaga
       61 caaatgagtt actaagaaat tggcatctga gaaagcccag gggacccagt gccagcagag
      121 tacccagcct gcaagcatcg tggactccct gccgggctga gaggtgggcc tttgtgggca
      181 ggagcagaga cgggcagagg acatccgact gtagggcaca tttatcagca aagtcccctt
      241 ttggtcatct ggagacacgt tttagaaggt gcctctcttt tccctgggaa gtccaatgtc
      301 tctgtgacct tggaaggagc cgcctgagac tctctgttca gctggcaccc acagccctga
      361 gccgccagag cctggagaag atgcagctgt acctggtgct tctcctcatc agctacttgc
      421 tgactccgat tggtgcctcc attttggggc gctgcgtggt ggctaagaaa ctctatgacg
      481 ggggcttaaa ttattttgag ggctacagcc ttgaaaactg ggtgtgcctg gcttattttg
      541 agagcaagtt caacccctcg gctgtctatg agaactcacg agatggctcc accggcttcg
      601 gcctctttca gatccgcgac aatgaatggt gtgaccatgg caagaacctc tgcagtgtgt
      661 cctgcacggc tttactgaat cccaacttaa aggatacaat cgagtgtgcc aagaaaatcg
      721 tgaaaggaaa acaagggatg ggagcatggc ccgtctggtc caggaactgc cagctgtcgg
      781 acattctgga tcggtggctg gatggctgtg agctgtaggc gcctgtgtgg tcctgcctca
      841 cttgccggcc gtgtcttggg actgagggcg cttttctgtt tgctgcttca atccatccgg
      901 ttatctcacc actgattgct ccagatggaa agggacaaca gtcctcactt catccggggg
      961 tacaaggtgc agaataaacc agctagttac tca
//
