LOCUS       NM_031342               1537 bp    mRNA    linear   ROD 10-APR-2024
DEFINITION  Rattus norvegicus lysophospholipase 2 (Lypla2), transcript variant
            1, mRNA.
ACCESSION   NM_031342
VERSION     NM_031342.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1537)
  AUTHORS   Abrami,L., Dallavilla,T., Sandoz,P.A., Demir,M., Kunz,B.,
            Savoglidis,G., Hatzimanikatis,V. and van der Goot,F.G.
  TITLE     Identification and dynamics of the human ZDHHC16-ZDHHC6
            palmitoylation cascade
  JOURNAL   Elife 6, e27826 (2017)
   PUBMED   28826475
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1537)
  AUTHORS   Yokoi,N., Fukata,Y., Sekiya,A., Murakami,T., Kobayashi,K. and
            Fukata,M.
  TITLE     Identification of PSD-95 Depalmitoylating Enzymes
  JOURNAL   J Neurosci 36 (24), 6431-6444 (2016)
   PUBMED   27307232
REFERENCE   3  (bases 1 to 1537)
  AUTHORS   Manna,J.D., Wepy,J.A., Hsu,K.L., Chang,J.W., Cravatt,B.F. and
            Marnett,L.J.
  TITLE     Identification of the major prostaglandin glycerol ester hydrolase
            in human cancer cells
  JOURNAL   J Biol Chem 289 (49), 33741-33753 (2014)
   PUBMED   25301951
REFERENCE   4  (bases 1 to 1537)
  AUTHORS   Guo,Z., Neilson,L.J., Zhong,H., Murray,P.S., Zanivan,S. and
            Zaidel-Bar,R.
  TITLE     E-cadherin interactome complexity and robustness resolved by
            quantitative proteomics
  JOURNAL   Sci Signal 7 (354), rs7 (2014)
   PUBMED   25468996
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1537)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   6  (bases 1 to 1537)
  AUTHORS   Toyoda,T., Sugimoto,H. and Yamashita,S.
  TITLE     Sequence, expression in Escherichia coli, and characterization of
            lysophospholipase II
  JOURNAL   Biochim Biophys Acta 1437 (2), 182-193 (1999)
   PUBMED   10064901
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Nov 26, 2020 this sequence version replaced NM_031342.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB021645.1, BC070503.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN12840105,
                                           SAMN12840106 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-60                JAXUCZ010000005.1  153486537-153486596 c
            61-166              JAXUCZ010000005.1  153484612-153484717 c
            167-198             JAXUCZ010000005.1  153484361-153484392 c
            199-264             JAXUCZ010000005.1  153484207-153484272 c
            265-312             JAXUCZ010000005.1  153483719-153483766 c
            313-383             JAXUCZ010000005.1  153483565-153483635 c
            384-457             JAXUCZ010000005.1  153483367-153483440 c
            458-559             JAXUCZ010000005.1  153483162-153483263 c
            560-733             JAXUCZ010000005.1  153482880-153483053 c
            734-1537            JAXUCZ010000005.1  153482000-153482803 c
FEATURES             Location/Qualifiers
     source          1..1537
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..1537
                     /gene="Lypla2"
                     /note="lysophospholipase 2"
                     /db_xref="GeneID:83510"
                     /db_xref="RGD:620210"
     exon            1..60
                     /gene="Lypla2"
                     /inference="alignment:Splign:2.1.0"
     exon            61..166
                     /gene="Lypla2"
                     /inference="alignment:Splign:2.1.0"
     CDS             89..784
                     /gene="Lypla2"
                     /EC_number="3.1.2.22"
                     /note="APT-2; LPL-II; lysoPLA II; lysophospholipase II;
                     palmitoyl-protein hydrolase"
                     /codon_start=1
                     /product="acyl-protein thioesterase 2"
                     /protein_id="NP_112632.1"
                     /db_xref="GeneID:83510"
                     /db_xref="RGD:620210"
                     /translation="MCGNNMSVPLLTDAATVSGAERETAAVIFLHGLGDTGHSWADAL
                     STIRLPHVKYICPHAPRIPVTLNMKMVMPSWFDLMGLSPDAPEDEAGIKKAAENIKAL
                     IEHEMKNGIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALSCWLPLHRNFPQAAN
                     GSAKDLAILQCHGELDPMVPVRFGALTAEKLRTVVTPARVQFKTYPGVMHSSCPQEMA
                     AVKEFLEKLLPPV"
     exon            167..198
                     /gene="Lypla2"
                     /inference="alignment:Splign:2.1.0"
     exon            199..264
                     /gene="Lypla2"
                     /inference="alignment:Splign:2.1.0"
     exon            265..312
                     /gene="Lypla2"
                     /inference="alignment:Splign:2.1.0"
     exon            313..383
                     /gene="Lypla2"
                     /inference="alignment:Splign:2.1.0"
     exon            384..457
                     /gene="Lypla2"
                     /inference="alignment:Splign:2.1.0"
     exon            458..559
                     /gene="Lypla2"
                     /inference="alignment:Splign:2.1.0"
     exon            560..733
                     /gene="Lypla2"
                     /inference="alignment:Splign:2.1.0"
     exon            734..1537
                     /gene="Lypla2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgtctgtgcg ggagaaaggg gagaatcgcc cgaacggtcg cggaagctcc tgggagtgag
       61 gcccagcctg caggaagccc tgcagtgtat gtgtggtaac aacatgtctg tgcccctgct
      121 caccgacgca gccaccgtgt ccggagctga gcgggaaacg gccgcggtta tttttttaca
      181 tggacttgga gacacagggc acagctgggc tgacgccctc tccaccatcc ggcttcctca
      241 tgtcaagtac atctgtcccc atgcgcccag gattcctgtg acactcaaca tgaagatggt
      301 aatgccctcc tggtttgacc tgatggggct gagtccagat gccccagagg atgaagccgg
      361 catcaagaag gccgcagaga acatcaaggc tttgattgaa cacgagatga agaacgggat
      421 tcctgccaac cgaatcgtcc tgggtggctt ttcgcagggt ggggccctgt ccctctatac
      481 agcacttacc tgcccccacc ctctggccgg catcgtggct ttgagctgct ggctgcctct
      541 gcaccggaac ttcccccaag cagccaatgg cagtgccaag gacctggcca tccttcaatg
      601 ccacggcgag ctggacccca tggtacctgt tcggtttggg gccctgacag ctgagaagct
      661 ccggacagtt gtcacacctg ccagggtcca gtttaagaca tacccaggtg tcatgcacag
      721 ctcctgtcct caggagatgg cagctgtaaa ggaatttctg gagaaacttc tgcctccggt
      781 ctaactagct gctggctccc atcgtggtcc ccagctcaca ggggacccag caagcaagga
      841 tctgagccgg tcgagcccct gtcccttctc ttcctaccct attctcttcc cacaggcctc
      901 tggggcaggt cgccgaggct ggccaggcct tcctgctggc ctcggtcatc tggaagtcag
      961 cagcaggggt gggctgctct cttaccccac ttccccagag gcgggcccca gcagcagtat
     1021 tggaggggct gaaggcagcg ggagaaaggg gcccagctgc tgacccgctc actcaggacc
     1081 tcacccacta gccccgcttt gggccccctc ctgtgacctc agggtttggc ccatggggcc
     1141 ctcaggggcc ccttcccccg tgattctgcc cggataatcg tctctcctgc ctcactgcag
     1201 ctgcttctgt cacgaatgtg tccatggccc cggggccctt gctgctgtag gctgcctgct
     1261 gctgggcagg ctggtcagtg aggaggtaga gtccctcagg ggcctcccct cagcccctcc
     1321 ccacagaggg gctgggccct gcctccccat ggccctttct tgcaggcctg gagcctgcag
     1381 ggctggattg aggttcaagg gcccccaatt ccctgctgtc tcacccccca ttatgtcccc
     1441 ccttagggcc agggaggtgg tgggggagga gttgtgtctt gtcttctgtc ttcatgtggt
     1501 tttgggtgtt tttcttgttt tgtcctggat tccgata
//
