LOCUS       NM_152848               1516 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus Ly49 inhibitory receptor 2 (Ly49i2), mRNA.
ACCESSION   NM_152848 XM_346718
VERSION     NM_152848.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1516)
  AUTHORS   Ma,B.J. and Kane,K.P.
  TITLE     Recognition of class I MHC by a rat Ly49 NK cell receptor is
            dependent on the identity of the P2 anchor amino acid of bound
            peptide
  JOURNAL   J Immunol 187 (6), 3267-3276 (2011)
   PUBMED   21841133
  REMARK    GeneRIF: the identity of the P2 peptide anchor residue is an
            integral component of MHC-I recognition by Ly49i2
REFERENCE   2  (bases 1 to 1516)
  AUTHORS   Naper,C., Hayashi,S., Joly,E., Butcher,G.W., Rolstad,B., Vaage,J.T.
            and Ryan,J.C.
  TITLE     Ly49i2 is an inhibitory rat natural killer cell receptor for an MHC
            class Ia molecule (RT1-A1c)
  JOURNAL   Eur J Immunol 32 (7), 2031-2036 (2002)
   PUBMED   12115624
  REMARK    GeneRIF: Ly49i2 is an inhibitory natural killer cell receptor for
            specific MHC class Ia molecule (RT1-A1(c))
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1 and AY115572.1.
            
            On Mar 2, 2021 this sequence version replaced NM_152848.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY115572.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760434 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-114               JAXUCZ010000004.1  166180569-166180682 c
            115-314             JAXUCZ010000004.1  166178739-166178938 c
            315-404             JAXUCZ010000004.1  166177250-166177339 c
            405-623             JAXUCZ010000004.1  166176146-166176364 c
            624-709             JAXUCZ010000004.1  166173646-166173731 c
            710-712             AY115572.1         711-713
            713-766             JAXUCZ010000004.1  166173589-166173642 c
            767-870             JAXUCZ010000004.1  166166581-166166684 c
            871-1516            JAXUCZ010000004.1  166156061-166156706 c
FEATURES             Location/Qualifiers
     source          1..1516
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..1516
                     /gene="Ly49i2"
                     /note="Ly49 inhibitory receptor 2"
                     /db_xref="GeneID:260324"
                     /db_xref="RGD:628669"
     exon            1..114
                     /gene="Ly49i2"
                     /inference="alignment:Splign:2.1.0"
     exon            115..314
                     /gene="Ly49i2"
                     /inference="alignment:Splign:2.1.0"
     CDS             203..1045
                     /gene="Ly49i2"
                     /note="inhibitory NK cell receptor for MHC class I
                     ligands; killer cell lectin-like receptor 5-like"
                     /codon_start=1
                     /product="Ly49 inhibitory receptor 2"
                     /protein_id="NP_690061.2"
                     /db_xref="GeneID:260324"
                     /db_xref="RGD:628669"
                     /translation="MTEQEVTYTTVRFHKSSVFQNEVRSEETQSAKEIGHRESSVPWK
                     LIVIALGILCSVLLVTVAVLVTNCLQYNHETHELQETQNSQHNCSTMENDIKLKEEML
                     RNMSIESTRYNALLDLINREQKRWYNKTKTVLAAPQHTGGCVEMHWLCYGIKCYYFII
                     DKRTWRKCIQTCQNYSLSFLKIHDKDELKFLQDHIIRDSYWIGLSYNNNKKEWSWIDN
                     TTLNCDLVAMISLHKTGNCKYFSMTGLHDDDCGKRHLCICEKGIEKYPAPLCSVNERS
                     QSAL"
     exon            315..404
                     /gene="Ly49i2"
                     /inference="alignment:Splign:2.1.0"
     exon            405..623
                     /gene="Ly49i2"
                     /inference="alignment:Splign:2.1.0"
     exon            624..766
                     /gene="Ly49i2"
                     /inference="alignment:Splign:2.1.0"
     exon            767..870
                     /gene="Ly49i2"
                     /inference="alignment:Splign:2.1.0"
     exon            871..1516
                     /gene="Ly49i2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtttttctt ttttctctga gcctattagt gtatacagac aagtaaagtt caacttttcc
       61 accaactgag tgatcaattt cctccacgag aatcgcttca ggatagagac acagatctag
      121 gtaccttcct ataggtggac atttaaactt tgaaaaaaaa aacaattctc aaggctccag
      181 tatacttcat atattcaaaa agatgactga acaggaggtt acttacacaa ctgtgagatt
      241 tcataagtcg tcagtgttcc agaacgaagt gaggtctgag gagactcaaa gtgctaaaga
      301 aataggccac agagagagtt cagtcccctg gaagctcatt gttatagctc ttggaatcct
      361 ctgttcagtt ctgctggtaa ctgttgcagt attggtgaca aactgtttgc agtataatca
      421 tgaaacacat gaactgcaag aaactcaaaa ctctcaacat aactgcagca ccatggaaaa
      481 tgacatcaaa ttaaaggaag aaatgctgag aaatatgtct atagagagta ctcgttacaa
      541 tgctcttctg gacttaatca acagagaaca gaagagatgg tacaacaaaa ctaagactgt
      601 tttagctgcc cctcagcaca caggtggttg tgttgaaatg cattggttat gctatggtat
      661 aaaatgttat tatttcatca tcgacaaaag aacatggcgt aaatgtatac agacctgcca
      721 gaattacagc ttatcctttc tgaagataca tgataaggat gaactgaagt tccttcagga
      781 ccacattatt cgagacagtt actggattgg attgtcatat aataataata aaaaggaatg
      841 gtcatggatt gacaacacca cattgaattg tgatttggtg gcaatgatat cactacacaa
      901 aacaggaaat tgtaaatatt tcagtatgac aggtctacat gatgatgact gtggtaaaag
      961 acatctctgt atctgtgaaa agggaataga aaaatatcct gccccattgt gcagtgtgaa
     1021 cgaaaggtca cagtctgctc tgtgaataaa gagatgagtt gcaaagcgaa gaagtcttct
     1081 gaaatttgtc ttaagagcag acacagtatt cccttctggc acatggagca gcttgcatgt
     1141 ggagaatgga catcctttgt tccaagaccc aaatgatttt cctcacattc tctcctgaat
     1201 gacacacaga accacatgga gaactcaata aataatgcac acatcacata ttcttttgga
     1261 tatttctaca gcccatggct tgttagtaca attaataaca aatctgcagt tgtgggtttt
     1321 catgtagagg ttagttacta tttggttttt tgtttgtttg tttgtttgtt tgtttttttt
     1381 tctgtttttt gatttttttt ttggtgtaga aaaagttagc atttttaaaa ccttttgaga
     1441 tgaggaactg tggatgggag gactgattgt ggttatgtct tgactgttaa taaataaaat
     1501 gattttgaaa acctta
//
