LOCUS       NM_001107565            2664 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus LTO1 maturation factor of ABCE1 (Lto1), mRNA.
ACCESSION   NM_001107565 XM_001066712 XM_219536
VERSION     NM_001107565.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2664)
  AUTHORS   Paul,V.D., Muhlenhoff,U., Stumpfig,M., Seebacher,J., Kugler,K.G.,
            Renicke,C., Taxis,C., Gavin,A.C., Pierik,A.J. and Lill,R.
  TITLE     The deca-GX3 proteins Yae1-Lto1 function as adaptors recruiting the
            ABC protein Rli1 for iron-sulfur cluster insertion
  JOURNAL   Elife 4, e08231 (2015)
   PUBMED   26182403
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2664)
  AUTHORS   Zhai,C., Li,Y., Mascarenhas,C., Lin,Q., Li,K., Vyrides,I.,
            Grant,C.M. and Panaretou,B.
  TITLE     The function of ORAOV1/LTO1, a gene that is overexpressed
            frequently in cancer: essential roles in the function and
            biogenesis of the ribosome
  JOURNAL   Oncogene 33 (4), 484-494 (2014)
   PUBMED   23318452
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473953.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_219536.4, XM_001066712.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00155311,
                              SAMN12840118 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2664
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q42"
     gene            1..2664
                     /gene="Lto1"
                     /gene_synonym="Oraov1"
                     /note="LTO1 maturation factor of ABCE1"
                     /db_xref="GeneID:309136"
                     /db_xref="RGD:1304637"
     exon            1..426
                     /gene="Lto1"
                     /gene_synonym="Oraov1"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..790
                     /gene="Lto1"
                     /gene_synonym="Oraov1"
                     /note="oral cancer-overexpressed protein 1; oral cancer
                     overexpressed 1; LTO1, ABCE1 maturation factor"
                     /codon_start=1
                     /product="protein LTO1 homolog"
                     /protein_id="NP_001101035.1"
                     /db_xref="GeneID:309136"
                     /db_xref="RGD:1304637"
                     /translation="MTGVRGPGESRDTAMAMEQDIFDAVVMADERWAERSVSAPPRQL
                     LCRPRGYPPSPSASCHFFLSFNCRTYGGIHESADGYVGQAPLDPEKSTGNAWAGRWPR
                     FHGEGYQEGYEEGSSLGIVEGKQYGVLHGAKIGSEIGCYRGFALAWKCLLHSGAGEKE
                     SRKMKVVEALITLLQDFPYDDPTYEKLHEDLERIRGKFRQLCSLLNVQPDFKVTAGGS
                     GLAF"
     exon            427..532
                     /gene="Lto1"
                     /gene_synonym="Oraov1"
                     /inference="alignment:Splign:2.1.0"
     exon            533..603
                     /gene="Lto1"
                     /gene_synonym="Oraov1"
                     /inference="alignment:Splign:2.1.0"
     exon            604..721
                     /gene="Lto1"
                     /gene_synonym="Oraov1"
                     /inference="alignment:Splign:2.1.0"
     exon            722..2664
                     /gene="Lto1"
                     /gene_synonym="Oraov1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttttttggct tctttagctt gccgtcctta cccgccctgc tccgcgcggc ataaacggaa
       61 gtggcttctt caatctgggc atttgtgctc gtgtctcgcc ggctggcgat tgctacacaa
      121 aatgacagga gtgcgaggac ccggggagag ccgagacacc gccatggcca tggagcagga
      181 catatttgac gccgtcgtga tggcggatga gaggtgggca gagagatccg tctccgcccc
      241 gccccggcag ctgctgtgcc gtcctcgggg atacccgcct tcgccatctg cgagctgcca
      301 ctttttcttg tcctttaatt gccgcacata cggcggtatt catgaatctg ctgatggata
      361 tgtcggacag gcccctttgg atcctgaaaa gtccacaggg aacgcctggg cggggcggtg
      421 gcccagattc catggggagg gatatcagga aggctatgaa gaaggcagta gcttgggaat
      481 cgttgaagga aagcagtatg gtgtgttaca tggagccaaa attggatctg agattggatg
      541 ctaccggggt tttgctcttg catggaaatg tctcctgcac agtggtgctg gtgagaaaga
      601 aagcaggaag atgaaggtgg tggaggctct gatcacgctg ctgcaggact ttccctatga
      661 tgatcccact tatgagaagc tccatgaaga cctggagaga atcagaggga aattcagaca
      721 gctgtgctca ctgctcaacg tgcagccgga cttcaaggtg actgcagggg gctctggact
      781 tgcattttga ggcccgaaga agagcagatg tctgcacatc aagtgtcaca gtgattaaag
      841 gcgcctgagg cacccattgt tctgtgagag gagcagtttg gccccccctg aggctctgcc
      901 tgggtgactt gcagtggtct gcaccctgcc ttctgcacag cagcagcaca ctcaagaggc
      961 agcttgccac tggccagagt gagtggtcct gagggtggga ctcacagagg cgggctgatg
     1021 tgaaatcagt tcatggaaag ccatgacagg agatctgctg tctgctgagc ctctgctggc
     1081 ctcgctcggg cctcctttgt tcactccatc cctctggcag ccccagaggt agataccatt
     1141 ctggcttaga gatgatgaaa tagacccatc cagtctaagg gctggcagca gagctggctc
     1201 tcactgcaga tccatgccct gcagtaccac atggtgcctt agcctccatc atgtgctgtc
     1261 attgccaaca ccactggagg acccagattt cctgctgtgt gcacaggact cggggtccac
     1321 tggatttgcc ttgcctctgg atgcctagct gagaagacaa gagcagcctg atcctgagga
     1381 agctgaagca tggccttcat gctgccctag gagtgggatg agcgctacac agtaggaaat
     1441 ggcagtggag ccaggcggca gtggcgcact ttagtcccag tgctggagag gcagcaggag
     1501 gatctctgag tctgaggtta gcctggtcta cagagggaat taaaaaacaa acaaacaaac
     1561 aaacaaacag tggcactagg ggaactactg ggaaccaaag caggactaga tggtggtcag
     1621 cactgtgaat gtgtagggct tgcctgggtg acatgtactt ccgttagcag cagcttgtgt
     1681 ttctggcatg gtattgacag gcagatgtaa agtgagctgg caggggtggg cccagtgctc
     1741 cccggcattt ctgcagagag aatggccttg tgttgtttgg aagcatcact gtcagttaaa
     1801 aacctatggc ctatgactta gggaggaaat agtggcggaa catctgggag agagaaagga
     1861 ttctgggata cagccaggcg ggagatccac cagggaggat gtgaggcgat gggtaaatag
     1921 tacctaagtg cagataacta gccacgtggc agaatgcagt taaaataaat gggttacctt
     1981 ttgttatgat ctagtcagag tagggcctag ctatatgtcc agggtatttg taaatgtatt
     2041 ttgagtctga gtcttatttt tggcagcatg gagctggaag gaagacctgg gcctaagttt
     2101 tacacatgtc acagatgtgg gcacacatga cagtatgtgt tgatatgccc ttctttgggt
     2161 ggccccattg taccccatct gtcccacttc agttctgtgt tgtaacaggg tcaccatgga
     2221 tgcatgccac ttggagtttt aggttctttc tgattttaat tttcttttac agacaggcac
     2281 tacataatcc aagctggcta taaaaggtga tcctcttgct tcagtctcct gagtgctggg
     2341 atcttaggcc tgtggcccta ggacactgtt taacatcatt tcacagcatc tgggtagagt
     2401 agagggacca ttgtgcagct ggagctgttc cctccttctg tcagcccagc cgagccagtg
     2461 ggaggctgag gcaggggcct ggggcaccat gcatctggcc tcctgagcct ctcaggttca
     2521 actccgctct cccagctgct cccaggatca gactctgcag tgtgctgctc tgggtactga
     2581 gcttggaggg ctgtggctgc tgctgtcatc atatcttact ttcctattat atttgggaaa
     2641 atgaataaat agtgtattta aagt
//
