LOCUS       NM_001024235            6669 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus listerin E3 ubiquitin protein ligase 1 (Ltn1),
            mRNA.
ACCESSION   NM_001024235 XM_213672
VERSION     NM_001024235.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6669)
  AUTHORS   Chu,J., Hong,N.A., Masuda,C.A., Jenkins,B.V., Nelms,K.A.,
            Goodnow,C.C., Glynne,R.J., Wu,H., Masliah,E., Joazeiro,C.A. and
            Kay,S.A.
  TITLE     A mouse forward genetics screen identifies LISTERIN as an E3
            ubiquitin ligase involved in neurodegeneration
  JOURNAL   Proc Natl Acad Sci U S A 106 (7), 2097-2103 (2009)
   PUBMED   19196968
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000011.1.
            
            On Sep 5, 2008 this sequence version replaced NM_001024235.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643287.26554.1,
                                           SRR26643429.40557.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-42                JAXUCZ010000011.1  40146970-40147011   c
            43-246              JAXUCZ010000011.1  40139951-40140154   c
            247-345             JAXUCZ010000011.1  40138608-40138706   c
            346-576             JAXUCZ010000011.1  40137931-40138161   c
            577-629             JAXUCZ010000011.1  40137213-40137265   c
            630-810             JAXUCZ010000011.1  40133203-40133383   c
            811-984             JAXUCZ010000011.1  40130342-40130515   c
            985-1175            JAXUCZ010000011.1  40128838-40129028   c
            1176-1311           JAXUCZ010000011.1  40127500-40127635   c
            1312-2124           JAXUCZ010000011.1  40124909-40125721   c
            2125-2166           JAXUCZ010000011.1  40124642-40124683   c
            2167-2356           JAXUCZ010000011.1  40121698-40121887   c
            2357-2596           JAXUCZ010000011.1  40120986-40121225   c
            2597-2750           JAXUCZ010000011.1  40119670-40119823   c
            2751-2895           JAXUCZ010000011.1  40118745-40118889   c
            2896-3082           JAXUCZ010000011.1  40118146-40118332   c
            3083-3242           JAXUCZ010000011.1  40115266-40115425   c
            3243-3347           JAXUCZ010000011.1  40114148-40114252   c
            3348-3490           JAXUCZ010000011.1  40112258-40112400   c
            3491-3626           JAXUCZ010000011.1  40110410-40110545   c
            3627-3771           JAXUCZ010000011.1  40110160-40110304   c
            3772-3985           JAXUCZ010000011.1  40109017-40109230   c
            3986-4223           JAXUCZ010000011.1  40108405-40108642   c
            4224-4298           JAXUCZ010000011.1  40107958-40108032   c
            4299-4485           JAXUCZ010000011.1  40106073-40106259   c
            4486-4657           JAXUCZ010000011.1  40097654-40097825   c
            4658-4878           JAXUCZ010000011.1  40096280-40096500   c
            4879-5073           JAXUCZ010000011.1  40095453-40095647   c
            5074-5241           JAXUCZ010000011.1  40093276-40093443   c
            5242-6669           JAXUCZ010000011.1  40090169-40091596   c
FEATURES             Location/Qualifiers
     source          1..6669
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q11"
     gene            1..6669
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /note="listerin E3 ubiquitin protein ligase 1"
                     /db_xref="GeneID:288308"
                     /db_xref="RGD:1311238"
     CDS             1..5304
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /EC_number="2.3.2.27"
                     /note="zinc finger protein 294; ring finger protein 160"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase listerin"
                     /protein_id="NP_001019406.2"
                     /db_xref="GeneID:288308"
                     /db_xref="RGD:1311238"
                     /translation="MGGKNKQRTKGNLRPSNSGRAAELLAKEQGTVPGFIGFGTSHSD
                     LGYVPAIQGAEDIDSLVDSDFRMVLRKLSKKDVTTKLKAMQEFGTMCTERDTEAVKGV
                     LPYWPRIFCKISLDHDRRVREATQQAFEKLILKVKKHLAPYLKSVMGYWLMAQCDTYP
                     PAATAAKDAFEAAFPPSKQPEAIVFCKEEITTVLQDHLLKETPDTLSDPQTVPEEERE
                     AKFHRVVTCSLLALKRLLCFLPNNELDSLEEKFRSLLSQNKFWKYGKHSVPQVRSAYF
                     ELVSALCQHVPQVMKEEAAKVSPSVLLSIDDSDPVVCPALWEAVLYTLTTVEDCWFHV
                     NAKKSVFPKLTAMIRDGGRGLAAVIYPYLLPFISKLPQSITEPKLDFFKNFLTSLVTG
                     LSTERTRSSSAECSAVIAAFFECLRFIMQQNLGEEEMVQMLIGEQLIPFIDIVLKDSG
                     LQHGPLFNHLADTLSSWEAKADVEQDAETVYNLEKVLLSFWERLSEICIEKISEPEAD
                     VKSVLGVSNLVGILQKPESSLKSNRKRNGKVRFVIDTPEAPKGSEKCVSSEGENSEGS
                     EGGGTGSSLSYKSSDVVSPLRKKPLEDLVCKLAEVSISFVNEQKSEQHLQFLSTLLDS
                     FSSGQVFKILLGDKQKNIVKAKPLEITKLAEKNPAVQFLYHKLIGWLNDSQKEDGGFL
                     VDILYSALRCCDSDVERKEVLDDLTQEDLKWSSLLRVIEKACSSSDKHALVTPWLKGS
                     ILGEKLVALADCLCGKDLESTISSECHSSEQWTLLRLALSQHLKNDYLIGEVYVARII
                     VKLHETLSKTKDFSEAADSDSSVSFVCDVIHSFFSSAGGGLLTPASEDLLLTLFQLCA
                     QSKERTHLPDFLICKLKNTLLSGVNLLVHQTASTYEQSTFLRLSVLWLKDQVQSSVLD
                     NESLQVLLSAVGDLLSTLVESEDTSLLGVYIGSVMPSDSEWEKMRQSLPVQWLHRPLL
                     EGRLSLNYECFKTDFKDQDTKTLPNHLCTSSLLSKMILIAQKKEIVLENDVLEKICAE
                     LLYSLQWCEELDNPPSFLSGFCEMLQKMNITYSNLSVLGNTSSLLQLLFDRSRKNGTL
                     WSLIIAKLILSRSISSDEVKPYYKRKESFFPLTEGNLHTIQSLCPFLSKEEKKEFSAQ
                     CIPAFLGWTKEDLCSINGAFGHLAIFNSCLQTRSIDDKQLLHGILKIITSWRKQHEDI
                     FLFSCNLSEASPEVLGLNIEIMRFLSLFLKYCSYPLAESEWDFIMCSMLAWLETASEN
                     QALYCVPLVQLFACVSFDLACDLSAFFDSITPDTVDNLPVNLISEWKEFFSKGIHGLL
                     LPLLVNATGEDKDLSETSFQNAVLKPMCETLTYISKDQLLSHKLPKRLVASQKTNLPE
                     HLQTLLNTLTPLLLFRARPVQIAAYHMLYKLMAELPQHDQDNLKSYGDEEEEPALSPP
                     AALMSLLSTQEELLENVLGCVPVGQIVPIKPLSEDFCYVLGYLLTWKLILTFFKAASS
                     QLRALYSMYLRKTKSLNKLLYHLFRLMPENPTYGETAIEVSNKDPKTFFTEELQLSIR
                     ETATLPYHIPHLACSVYHMTLKDLPAMVRLWWNSSEKRVFNIVDRFTSKYVSSVLSFQ
                     EISSVQTSTQLFNGMTVKARATTREVMATYTIEDIVIELIIQLPSNYPLGSITVESGK
                     RVGVAVQQWRNWMLQLSTYLTHQNGSIMDGLALWKNNVDKRFEGVEDCMICFSVIHGF
                     NYSLPKKACRTCKKKFHSACLYKWFTSSNKSTCPLCRETFF"
     exon            1..42
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            43..246
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            247..345
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            346..576
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            577..629
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            630..810
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            811..984
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1175
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            1176..1311
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            1312..2124
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            2125..2166
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            2167..2356
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            2357..2596
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            2597..2750
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            2751..2895
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            2896..3082
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            3083..3242
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            3243..3347
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            3348..3490
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            3491..3626
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            3627..3771
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            3772..3985
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            3986..4223
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            4224..4298
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            4299..4485
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            4486..4657
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            4658..4878
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            4879..5073
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            5074..5241
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
     exon            5242..6669
                     /gene="Ltn1"
                     /gene_synonym="Rnf160; Zfp294; Znf294"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgggcggga agaacaagca gcggaccaag gggaacctga ggccttcaaa cagtggccga
       61 gctgcagaac tccttgccaa agagcagggg acagtccctg gatttattgg ttttggaaca
      121 tctcacagcg acctgggcta cgttcctgct attcaaggcg cggaagacat agacagtctt
      181 gtagattctg atttccgaat ggtgctgcgg aaactttcca aaaaagatgt tacaacaaaa
      241 ttaaaggcaa tgcaagaatt tggaactatg tgcacagaga gagacacaga agctgtaaaa
      301 ggggttcttc catactggcc aagaatcttc tgcaaaatct cccttgatca tgaccgcagg
      361 gttcgagaag cgacgcaaca agcttttgaa aaacttatcc ttaaagtaaa gaagcactta
      421 gctccatatt taaaaagtgt aatgggatat tggctaatgg ctcagtgtga cacatatcca
      481 ccagctgcaa ctgcagcgaa agatgccttt gaagccgctt tccctccaag caagcaacct
      541 gaagctatag tgttttgtaa ggaagaaatt acaactgtac tacaggacca tcttttgaaa
      601 gaaactcccg atacgctcag tgaccctcaa actgtcccag aggaagagag agaggctaag
      661 ttccatagag ttgtaacatg ctctttattg gccctgaaga gattgctctg cttcttacct
      721 aacaatgagc tcgattctct ggaggagaaa tttagatcgc tgttgtcgca gaataagttt
      781 tggaagtacg gaaagcacag tgtgcctcag gtccgctcag cgtactttga attagtttct
      841 gctttgtgcc agcatgtacc ccaggtgatg aaggaggaag ctgccaaagt gagcccgtct
      901 gtcctgctca gcattgatga cagtgaccct gtggtctgcc cagctctctg ggaagctgtg
      961 ctctacacgc tgacaactgt tgaggactgt tggtttcatg taaatgccaa aaaaagtgtg
     1021 tttcccaagc tgacggccat gatccgtgac ggtggccgtg gccttgctgc tgttatttat
     1081 ccttatctct taccgttcat cagcaaactc cctcagtcca tcacagagcc gaagctggac
     1141 ttcttcaaaa actttctcac ctctctagtt actgggctgt caacagagag gaccagatcg
     1201 agctctgctg agtgctcagc ggtcattgcg gcgtttttcg agtgcttacg gtttataatg
     1261 cagcagaacc taggtgagga ggagatggtg cagatgctca tcggtgagca gttgatccca
     1321 tttattgata tagttctcaa agactcagga ctgcaacacg ggccgctgtt taaccattta
     1381 gcagacacgt tgagttcttg ggaagccaaa gcagatgtag aacaagacgc cgaaactgtt
     1441 tacaacctgg agaaggttct gctaagtttc tgggaaaggc tgtcagagat ctgcattgag
     1501 aagatcagtg agccagaagc agacgtgaag tctgttttgg gtgtatctaa cctagtaggg
     1561 atccttcaga aaccagagag ctcactgaag tcaaacagaa agaggaatgg caaggtcagg
     1621 tttgtcatcg atacacctga agctcctaag gggagtgaaa aatgtgtgtc ttcagaagga
     1681 gagaacagcg aaggctctga aggaggaggg actgggtcct ctctcagtta caaatcttca
     1741 gacgtagtat ctcctctaag gaaaaaacct ctggaagact tagtctgtaa acttgcagag
     1801 gtgagcatta gctttgtcaa tgagcagaag tcagagcaac acctgcagtt tctctccacg
     1861 ctgcttgatt ccttctcctc aggccaggtg tttaaaattc tccttggtga caaacagaag
     1921 aatattgtca aagccaaacc tctggaaata accaaacttg cagaaaagaa ccctgcagtt
     1981 cagttcttat atcataaatt gataggctgg ctaaatgaca gccagaagga agacgggggc
     2041 ttcctggtgg acatcttgta tagtgctctc cgatgctgtg acagtgacgt ggagaggaag
     2101 gaagtcttgg atgatctaac tcaggaggac ctgaagtgga gctctcttct tcgggtcatt
     2161 gaaaaggcat gttctagttc agacaaacat gctttagtaa ctccttggct aaaaggcagt
     2221 attcttggag agaaattggt tgccttggca gactgtcttt gtggtaaaga cttggaatcc
     2281 acaatatctt ccgaatgtca ctcttccgaa cagtggactc tgctaagact ggcactgtct
     2341 cagcacctta aaaacgatta cttgattgga gaagtgtacg ttgcaagaat tattgttaaa
     2401 cttcatgaaa ctttatccaa aaccaaggac ttctcagagg cagcagacag tgactcttca
     2461 gtgtcttttg tctgtgatgt gatccatagc ttcttcagct cagcaggagg aggcttgcta
     2521 acgcccgcat ccgaagactt gttgttaact ctctttcagt tatgcgccca gagcaaagaa
     2581 cgaacacact tgccagattt tctgatctgt aaactgaaga atactttgct ttctggtgta
     2641 aatttattgg tccatcaaac tgcaagtaca tatgagcaga gcacctttct acgtttgtct
     2701 gttctatggc tgaaggacca ggttcagtct tcagttttgg ataacgagag tcttcaggtc
     2761 ctcttgtctg ctgttggaga cttgctgagt actcttgtag agagtgagga cacttctctt
     2821 cttggagtct atattggaag tgtaatgccc agtgacagcg agtgggaaaa gatgaggcag
     2881 tctcttcctg ttcagtggtt acacagacct cttttagagg gaaggctgag tttaaattat
     2941 gaatgcttca agactgactt taaggatcaa gatacaaaga ctcttcccaa ccatttgtgc
     3001 acttcatcat tattgagcaa aatgatctta attgcacaga aaaaggaaat agtcctagaa
     3061 aacgatgtcc ttgagaaaat atgtgcggag ctgctgtatt cactgcagtg gtgtgaagaa
     3121 ctcgacaatc cgccatcttt tctaagtgga ttttgtgaaa tgcttcaaaa aatgaatata
     3181 acttacagca acttgtctgt acttggtaat acttctagcc tcttgcagct tttatttgac
     3241 agatctagaa aaaatggcac actttggtct cttattattg ctaaattgat cctttcccga
     3301 agtatttcat ctgatgaagt aaaaccatat tataagagaa aagaaagctt cttccctcta
     3361 acagaaggta atttgcatac cattcaaagt ctctgtccat ttttgtctaa agaagaaaag
     3421 aaggaattta gtgctcagtg tattcctgct tttttgggtt ggactaaaga agacctttgc
     3481 agtattaatg gagcttttgg acatcttgcc attttcaatt cttgcctgca aaccagaagt
     3541 atagatgaca aacagctatt gcatggtata ttaaaaatta taacaagctg gaggaaacag
     3601 catgaagata tttttctctt cagttgtaat ctatcggaag caagtccaga ggtccttggt
     3661 ttaaacatag aaatcatgcg attcctttcc ttgtttctga agtactgctc gtacccgcta
     3721 gcagagagcg aatgggattt catcatgtgc tccatgttgg cttggttgga gacagccagt
     3781 gagaaccagg ccctgtactg tgttccgctg gtacagctgt ttgcctgtgt cagctttgat
     3841 ctggcctgtg acctcagtgc cttttttgac tcgataactc cagatactgt tgacaatctt
     3901 cctgtaaatc taatcagtga gtggaaagaa tttttctcta aaggcatcca cggtttgcta
     3961 ttgcctcttt tggtaaatgc cacaggagaa gacaaagacc tgtctgaaac gtcctttcag
     4021 aacgcagtgc tgaaacccat gtgtgaaacg ctaacataca tctctaagga ccagctgctg
     4081 agtcacaagc tccccaagag attggttgcc agccagaaaa caaacttgcc agagcacctc
     4141 cagactttgc tgaatacttt gaccccactg cttctcttca gagccagacc tgtgcaaatt
     4201 gccgcttacc acatgctcta caaactgatg gctgaattgc cgcagcatga ccaggacaat
     4261 ctcaagtcct atggagatga agaggaggag ccagccttgt caccgccggc cgcgctgatg
     4321 tctctcctca gcactcagga ggaactgctg gagaatgtct tgggctgtgt ccctgtgggc
     4381 cagatagttc ccattaagcc actgagtgag gacttctgct acgttctggg ctacctcctc
     4441 acttggaagc tgatactcac tttcttcaaa gctgcttcgt cccagcttcg tgctctgtat
     4501 tcaatgtacc tacggaaaac caagagtctg aacaaattac tctaccacct gttcagactt
     4561 atgccagaaa atcctactta cggagagacg gcgattgagg tgtcaaataa agaccccaag
     4621 accttcttca ccgaggagct tcagctgagt attagagaaa cagcaacact gccgtatcat
     4681 atcccacacc tggcatgttc agtctatcac atgactttaa aggacttgcc tgccatggtt
     4741 aggctatggt ggaatagcag tgagaagcgt gtcttcaata ttgtagatag atttacaagc
     4801 aaatatgtca gcagtgttct ttcttttcaa gaaatatctt ctgtacagac aagcacacag
     4861 ctattcaatg gcatgacggt taaggcacga gctactactc gagaagtgat ggccacttac
     4921 accatcgaag acatagtcat tgaactcatc atacagctgc cttccaacta cccactgggt
     4981 tcaataacag tggagagcgg gaaaagagtc ggggtggccg tgcagcagtg gcgcaactgg
     5041 atgctgcagc tgagcaccta cctcacccac cagaacggaa gcatcatgga cggcttagcg
     5101 ttgtggaaga ataacgtaga caaacgcttt gagggcgtcg aagattgtat gatctgcttc
     5161 tcagttattc atggtttcaa ctattccctt cccaaaaaag cctgtagaac atgcaagaaa
     5221 aagttccact cagcttgctt gtacaaatgg tttacatcta gcaacaagtc cacttgtcca
     5281 ctctgtcgtg agaccttttt ctgaggtgtt ttcattggaa gttgtccctg cagaaggtca
     5341 agccagaggg aatggatttg gctcaatctt gaagtactgg cgtgaagcca acgagcatga
     5401 cagaaatgcc atcgctgtca gtgtgaccct caagtcaggc tcacctctct gtagattgct
     5461 ttgtaaatct ttggaaactt ttcttttaca aaagaatatt acatatttga gagaaaatat
     5521 ttatattaat ggcttaatct ctttgtatat ttaaaattga aaataaatat ctcttctcaa
     5581 aaatattcta aattatagaa ctgaaatttg tgaaagcata aactatatta taacgtgtca
     5641 gagcacccaa tgtgttggtc tgtgctgtag aacagtccag gtgtaaggca aatgaattga
     5701 gccgatttac atctgcagta aaactacggc ttgttcgtta agcgatgttt tgttaatgac
     5761 aaacgataat taaagattac tctgactttc atagtttgaa tgacacagtg aggctgagct
     5821 atttctaccc tcatccagag ctgtttgaag catcctccga aatctcacat gacgaaggga
     5881 ctaagtgaac tctaaggggc tttgtcgaga attgtgaaat tcatcactta catccttgac
     5941 actaatcttt tgcttgtgaa agaatcattt ccatgttaat gagatttgaa ctgtaaatgt
     6001 gttggttgaa tctgttactc agtgagacta caaagagtgg gaatctaaag gaagcagttg
     6061 tttgattagt ttgtgaagta aaatggtagc agtctatcaa aggaaaattg ttactaaagt
     6121 ataatcatgt gtggagaaac aatatttaaa aatcttgtag gagactgtaa atttgtaagc
     6181 agagtttgct attctcatta gccatagtta acaccaaatc aggaattggg ggagctaatt
     6241 acttaaaact atcaggaatg aaggatatag ttctgagtaa aattaatttt tgttttgttt
     6301 ttgttttgag ataggatttc acaatgtagc tctgggctgg gctggaactc atcccgtaga
     6361 ccagactagc ctggaactca agagatttgc ctgtctctgc ttcccaagtg ctggggttaa
     6421 agttcaccac caaacctggt ggaattatgt cttaatggat tgaagtgtgt aaacacgtga
     6481 cgatctgcct ttggttacag tacccttgcc tttaaagctg tattcacagt ataaagtgtg
     6541 gaagcttgga tcacagtctt ccattgcaca tctagtagtt aggatacctc aagagtcagt
     6601 tcatcatctg tgtttcaaat gttcgattag aagggtgcaa ctcgtgtcaa ataaaattac
     6661 tgcttacca
//
