LOCUS       NM_001008315            2103 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus lymphotoxin beta receptor (Ltbr), mRNA.
ACCESSION   NM_001008315 XM_238382
VERSION     NM_001008315.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2103)
  AUTHORS   Satpathy AT, Briseno CG, Lee JS, Ng D, Manieri NA, Kc W, Wu X,
            Thomas SR, Lee WL, Turkoz M, McDonald KG, Meredith MM, Song C,
            Guidos CJ, Newberry RD, Ouyang W, Murphy TL, Stappenbeck TS,
            Gommerman JL, Nussenzweig MC, Colonna M, Kopan R and Murphy KM.
  TITLE     Notch2-dependent classical dendritic cells orchestrate intestinal
            immunity to attaching-and-effacing bacterial pathogens
  JOURNAL   Nat Immunol 14 (9), 937-948 (2013)
   PUBMED   23913046
REFERENCE   2  (bases 1 to 2103)
  AUTHORS   Liu HP, Chung PJ, Liang CL and Chang YS.
  TITLE     The MYND domain-containing protein BRAM1 inhibits lymphotoxin beta
            receptor-mediated signaling through affecting receptor
            oligomerization
  JOURNAL   Cell Signal 23 (1), 80-88 (2011)
   PUBMED   20732415
REFERENCE   3  (bases 1 to 2103)
  AUTHORS   Smith AJ, Karpova Y, D'Agostino R Jr, Willingham M and Kulik G.
  TITLE     Expression of the Bcl-2 protein BAD promotes prostate cancer growth
  JOURNAL   PLoS One 4 (7), e6224 (2009)
   PUBMED   19593445
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2103)
  AUTHORS   Matsuda A, Suzuki Y, Honda G, Muramatsu S, Matsuzaki O, Nagano Y,
            Doi T, Shimotohno K, Harada T, Nishida E, Hayashi H and Sugano S.
  TITLE     Large-scale identification and characterization of human genes that
            activate NF-kappaB and MAPK signaling pathways
  JOURNAL   Oncogene 22 (21), 3307-3318 (2003)
   PUBMED   12761501
REFERENCE   5  (bases 1 to 2103)
  AUTHORS   Zapata JM, Pawlowski K, Haas E, Ware CF, Godzik A and Reed JC.
  TITLE     A diverse family of proteins containing tumor necrosis factor
            receptor-associated factor domains
  JOURNAL   J Biol Chem 276 (26), 24242-24252 (2001)
   PUBMED   11279055
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC085880.1.
            
            On Dec 16, 2004 this sequence version replaced XM_238382.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085880.1, SRR8487227.231332.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760494, SAMN16676811
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2103
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..2103
                     /gene="Ltbr"
                     /note="lymphotoxin beta receptor"
                     /db_xref="GeneID:297604"
                     /db_xref="RGD:1309448"
     exon            1..285
                     /gene="Ltbr"
                     /inference="alignment:Splign:2.1.0"
     CDS             190..1440
                     /gene="Ltbr"
                     /note="lymphotoxin B receptor; tumor necrosis factor
                     receptor superfamily member 3; lymphotoxin beta receptor
                     (TNFR superfamily, member 3)"
                     /codon_start=1
                     /product="tumor necrosis factor receptor superfamily
                     member 3 precursor"
                     /protein_id="NP_001008316.1"
                     /db_xref="GeneID:297604"
                     /db_xref="RGD:1309448"
                     /translation="MRLPGASSPCGLVWGPLLLGFCGLLVASQPQLVPPYRIENQTCW
                     DPDKEYYEPLHQVCCSRCPPGKFVHAVCSPSQDTVCKTCLHNSYNEHWNHLFSCQLCR
                     PCDSVLGFEEIAPCTSDRKPECRCKPGMSCVYLDNECVHCEEERLVLCRPGTEAEVTD
                     EIMDTEVNCVPCKPGHFQNTSSPRARCQPHTRCESQGLVEAASGTSYSDTICKNPPEA
                     AGTMLLLAILLSLVFFLLFTTVLACAWMRHPSLCRKLGTLLKRHPEGEESPPCQPPRA
                     NPHFRDLAEPLLPMSGDLSPAPAGPPTAPSLEEVVLQQQSPLIQARELEAEPGEHGQV
                     AHGANGIHVTGGSVTVTGNIYIYNGPVLGGTRGPGDPPAPPEPPYPTPEEGAPGPSEL
                     STPYQEDGKAWHLAETETLGCQDL"
     exon            286..382
                     /gene="Ltbr"
                     /inference="alignment:Splign:2.1.0"
     exon            383..508
                     /gene="Ltbr"
                     /inference="alignment:Splign:2.1.0"
     exon            509..667
                     /gene="Ltbr"
                     /inference="alignment:Splign:2.1.0"
     exon            668..764
                     /gene="Ltbr"
                     /inference="alignment:Splign:2.1.0"
     exon            765..844
                     /gene="Ltbr"
                     /inference="alignment:Splign:2.1.0"
     exon            845..955
                     /gene="Ltbr"
                     /inference="alignment:Splign:2.1.0"
     exon            956..981
                     /gene="Ltbr"
                     /inference="alignment:Splign:2.1.0"
     exon            982..1198
                     /gene="Ltbr"
                     /inference="alignment:Splign:2.1.0"
     exon            1199..2075
                     /gene="Ltbr"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tccactccca cttcctgagc ccggcactgg agccctggag gccaggcccg gccgctcccg
       61 gcccccgggg gcacgtcggc ccagccacca ggcttgggaa gtcgtggcca acgctgctca
      121 ggacgtccgg gcttcccacc ttcctcctag gcctccaccc ggtctggtca gccgacccga
      181 aaggccgcca tgcgcctgcc tggggcctcc tctccctgcg gcctggtctg gggaccactc
      241 ctgctgggat tctgcgggct cctggtggcc tctcagcccc agctggtgcc cccatatcgc
      301 atagaaaacc aaacttgctg ggacccggac aaggaatact acgagcctct gcatcaagtc
      361 tgctgctccc gctgtccccc aggcaagttt gtccatgctg tctgcagccc cagccaagac
      421 acggtttgca agacttgcct ccataattcc tacaacgaac actggaacca tctcttctcc
      481 tgccagctgt gccgcccctg tgactctgtg ctgggcttcg aggagattgc cccctgcacc
      541 agcgatcgga aacccgagtg ccgctgcaag ccggggatgt cctgcgtgta tttggacaat
      601 gagtgtgtgc actgtgagga ggagcggctt gtactctgcc ggcctggcac agaagctgag
      661 gtcacagatg aaattatgga tactgaagtc aactgtgtcc cctgtaagcc aggacacttc
      721 cagaacacgt cctcccccag agcccgctgt caaccccaca ccaggtgtga gagccagggc
      781 ctggtggagg cagcttcagg tacctcgtac tctgacacca tctgtaaaaa tccacccgag
      841 gcagcaggaa caatgctgct actagccatc ctgctgtcgc tggtcttctt tctgcttttc
      901 accactgtcc tggcctgtgc ctggatgagg cacccttccc tctgcagaaa gctgggtact
      961 ctgctcaaga ggcatccaga gggagaagaa tctcccccct gccagcctcc aagagccaac
     1021 ccacatttcc gtgacctggc agagccactc ctacccatgt ctggagactt gtccccagcc
     1081 cctgctggac ccccaacggc cccctccttg gaggaagtgg tgctacagca gcagagtccc
     1141 ctgatccagg ccagggagct ggaggctgag cctggggaac atggccaggt ggcccacggt
     1201 gcgaatggca ttcacgtgac cggaggctct gtgactgtca ccggcaatat ctacatatac
     1261 aatgggccag tgctgggggg aacacggggc cctggagacc ctccagctcc ccctgagcct
     1321 ccatacccga ctcccgaaga gggagcgcct ggcccctctg agctgtctac accctaccag
     1381 gaggatggca aagcttggca tctggctgag acagagacac tagggtgcca agacctctga
     1441 cggggccaag ggacctatta gccacccatg cctgatggca tctgggaaag gcaaggagga
     1501 gagagggtcc agcaccttct tcctgaggct gctctaccca ccaggactca cagagtttgg
     1561 ctgggctctg agatacagag ccctaaggga cttggcctca gacacctctt cagagagaca
     1621 ctagcggggc accgtgcccg cccaggcccc tgacgaccgc ctgagcaagc ctgagacctt
     1681 gttgcagacc caccagctcc cagaggcctc agacacaggc aaggcttgtg accccaccat
     1741 gcctctctga gccctaaaca tggcagagga gggagctggg cccagggtca ctttcaagga
     1801 catccgggga ccttgcaagg ctttgtggtg ctcatcccca accttcagag gccttgaggg
     1861 cttgtactgc gtggaccaag atagaccctg ggtgaacatg atgtcgcatg gaggagcacc
     1921 cctcccttgc tcctggggga gagaggacag tgagaagggc aggggggctt cagtagcatt
     1981 accacatgtg gaggacagtt tgggaacggg agaaagagta caagtgtatt tatgaattgt
     2041 aaccacatgc aaataaagac aagatggaga tccttaaaaa aaaaaaaaaa aaaaaaaaaa
     2101 aaa
//
