LOCUS       XM_006228570            5009 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus latent transforming growth factor beta
            binding protein 4 (Ltbp4), transcript variant X2, mRNA.
ACCESSION   XM_006228570
VERSION     XM_006228570.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006228570.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006228570.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5009
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5009
                     /gene="Ltbp4"
                     /note="latent transforming growth factor beta binding
                     protein 4; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 mRNAs, 57 ESTs, 4 long SRA
                     reads, 19 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 85 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:292734"
                     /db_xref="RGD:1307033"
     CDS             54..4748
                     /gene="Ltbp4"
                     /codon_start=1
                     /product="latent-transforming growth factor beta-binding
                     protein 4 isoform X2"
                     /protein_id="XP_006228632.1"
                     /db_xref="GeneID:292734"
                     /db_xref="RGD:1307033"
                     /translation="MAGGARLLWVSLLVLLAQLGPQPGLGRPRERLRVRFTPAVCGLR
                     CIHGPTGSRCTPTCAPRNTTSVDSGAPGGAAPGGPGFRAFLCPLICHNGGVCVKPDRC
                     LCPPDFAGKFCQLHSSGARPPAPAMPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHP
                     QEASVVVHQVERVSGPWEEANSEALARAEAAARAEAAAPYTVLAQSAPREDGYSDASG
                     FGYCFRELRGSECASPLPGLRTQEVCCRGEGLAWGVHDCHPCAEHLGNSNRVSGPNGL
                     CPTGFERVNGSCVDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHV
                     ISEAKGPCYRVLQDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPYGSEGFREIC
                     PAGPGYHYSASDLRYNTRPLNPDPPRVTFNQPRAPPVTLRPPTGFLPTRRPEPRPDPG
                     PQPELRPRPEPQPRPEFPLPSIPAWTGPEIPESGTSSSMCQRNPQVCGPGRCVSRPGG
                     YTCACDPGFRLGPQGTRCIDVDECRRVPTPCAPGRCENTPGSFRCVCGTGFRAGPRAT
                     ECLDVDECRRVPPPCDRGRCENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCG
                     RGACENLPGSFRCVCPAGFLGSACEEDVDECAQQPPPCGPGRCDNTLGSFHCACPAGF
                     RSRGPGAPCQDVDECARSPSPCAYGRCENTEGSFKCVCPTGFQPNAAGSECEDVDECE
                     NHLACPGQECVNSPGSFQCRACPVGYHLHRGRCTDVDECNSGTPCGLHGQCTNAQGSF
                     HCSCSTGYRAPSGRPGPCADINECLEGDFCFPHGECLNTDGSFTCTCAPGYRPGPRGA
                     SCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDIDECRERGPALCG
                     SQRCENSPGSYRCVRDCDPGYHPGPEGTCDDVDECREYGSAICGAQRCENTPGSYRCT
                     PACDPGYQPTPGGGCQDVDECRNRSFCGAHAMCQNLPGSFQCVCDQGYEGARDGRHCV
                     DVNECETLQGVCGSALCENVEGSFLCVCPTSPEEFDPMTGRCVPPRTPAGTFPGSQPQ
                     APASPSLPARPPAPPPPRRPSPPRQGPVSSGRRECYFDTAAPDACDNILARNVTWQEC
                     CCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLVPSGDLSARRDVDECQLFQDQV
                     CKSGVCVNTAPGYSCYCNNGFYYHAHRLECVDNDECADEEPACEGGRCVNTVGSYHCT
                     CEPPLVLDGSRRRCVSNESQSLDDNLGVCWQEVGPDLVCSRPRLDRQATYTECCCLYG
                     EAWGMDCALCPAQDSDDFEALCNVLRPPAYGPPRPGGFGLPYEYGPDIGPPYQSLPYG
                     PDLYPPPVLPYDPYPPPPGPFARREAPYGAPPFEMPDFEDDGDPYGETEAPDPPSRGT
                     GWPYRSRDTRGSFPEPEESSERGSYTGALSEPYEGLEAEECGILDGCAHGRCVRVPEG
                     FTCDCFDGYRLDITRMSCVDINECDEAEATSPLCVNARCVNTDGSFRCICRPGFAPTH
                     QPHHCAPARPRA"
ORIGIN      
        1 gggcccctcg ggcgggctgg ggcggcggcg cggtggagcg cggcgctgca gccatggcgg
       61 gcggcgcgcg gctgctctgg gtgtcgctat tggtgctgct ggcgcagctg gggccgcagc
      121 ccggactggg ccgaccccga gagcgtcttc gcgtgcgctt cacccccgcc gtgtgcggcc
      181 tgcgttgcat ccacgggccc actggctccc gctgtacccc gacctgcgcg ccccgcaaca
      241 ccaccagcgt ggacagcggc gcgcccggcg gggcggcccc ggggggaccc ggcttccgcg
      301 cctttctatg tcccttgatc tgtcacaacg gtggtgtgtg tgtgaagcct gaccgctgcc
      361 tttgcccccc ggacttcgct ggcaaattct gtcaattgca ttcttcgggg gcccggcccc
      421 cggccccagc catgccgggc cttacccgtt cggtttacac aatgccacta gccaatcacc
      481 gcgatgatga acacggcgta gcatcgatgg tgagtgtgca cgtggagcac cctcaggagg
      541 catcggtggt ggtgcaccag gtggaacgtg tgtctggccc ctgggaggag gcgaactctg
      601 aagccctagc cagggctgaa gcggcagcac gggccgaggc ggcggcgccc tacacagtgc
      661 tggcacagag cgcgccacgc gaggacggct actcagacgc ctccggcttt ggttactgtt
      721 tcagggaact gcgcggaagc gaatgtgcat cgccgctgcc gggactccgg acgcaggaag
      781 tatgctgccg aggggagggc ttggcctggg gtgttcatga ttgtcacccg tgcgcggaac
      841 acttggggaa ctccaaccga gtgagtggtc caaatgggct ttgtccaacc ggattcgaaa
      901 gagttaatgg gtcctgtgta gatgtggatg agtgcgccac aggtgggcgt tgccaacacg
      961 gagagtgtgc caacactcgt ggcgggtaca cgtgtgtatg tccggatggt ttcctcctag
     1021 actcttcccg cagcagctgc atctcccaac acgtgatctc ggaggcaaag gggccctgct
     1081 acagagtgct ccaagatggc ggatgctcgc tgcccattct tcgaaatatc accaaacaga
     1141 tctgctgctg tagccgcgtg ggcaaggcgt ggggccgagg ctgccagctc tgtccacctt
     1201 atggttcaga gggttttcgg gagatctgtc cagctggccc tggttaccac tattcagctt
     1261 ctgacctccg ctacaacacc agacccctaa acccggatcc acctcgagtg actttcaatc
     1321 agccacgtgc tccacctgtc actcttaggc cacccacagg ttttctgccc actcgtcgac
     1381 ctgagccccg tcctgaccct gggccacagc ctgaactccg gcctcgacct gaaccccagc
     1441 ctcggcctga atttcccctg cccagcatcc ctgcttggac cggtccagag attcctgaat
     1501 caggtacctc ttccagcatg tgtcagcgaa atccccaggt ttgtggtcct ggacgctgcg
     1561 tttctcggcc aggcggctac acctgtgcct gcgacccagg tttccggctc ggcccccagg
     1621 gcactcgctg tattgacgta gatgaatgtc gccgcgtccc tacaccctgt gctcctggac
     1681 gctgcgagaa tacaccaggc agctttcgct gcgtgtgcgg caccggcttc cgagcaggcc
     1741 cacgggctac agagtgtttg gatgtggacg agtgccgccg agtgccgccg ccgtgtgacc
     1801 gcgggcgctg cgagaacaca ccaggaagtt tcctatgtgt gtgtcccgcc gggtaccagg
     1861 cagcaccgca cggagccagc tgccaggatg ttgatgaatg cacccagagc ccaggcctct
     1921 gtggccgcgg ggcctgcgaa aacctgcccg gctctttccg ctgtgtttgc ccggctggtt
     1981 tcctcggctc agcgtgtgaa gaagatgtgg acgaatgtgc ccagcagcct ccgccctgcg
     2041 ggccaggccg ctgcgacaac accttgggtt cattccactg tgcctgtcca gctggcttcc
     2101 gctcccgagg gccaggggcc ccctgccaag atgtggacga atgtgcccgg agcccctcac
     2161 cttgtgccta tggccgctgt gaaaacacgg aagggagctt caagtgtgtc tgccctacag
     2221 gcttccaacc caacgctgcg ggctccgagt gcgaggatgt ggatgagtgt gagaaccact
     2281 tggcctgtcc tgggcaggag tgtgtgaact caccaggctc cttccagtgc cgggcctgcc
     2341 ctgttggcta ccaccttcac cgtggcagat gcactgacgt ggacgaatgc aattccggca
     2401 ccccttgtgg tctccatggc caatgcacga atgcccaagg ctccttccac tgcagctgct
     2461 cgacaggtta ccgggcacca tctggtcgac ccgggccctg tgcagatata aatgagtgtc
     2521 tggaaggcga cttctgcttc ccccatggag agtgcctcaa caccgacggc tcctttacct
     2581 gtacctgtgc ccctggctat cggcctggac ctcgtggagc atcttgtctg gacgtggacg
     2641 agtgcagtga ggaggatctt tgccagagcg gcatctgtac caacactgac ggctccttcg
     2701 aatgcatctg tcctcctgga caccgtgctg gccctgacct tgcctcctgc cttgacattg
     2761 acgagtgtcg tgaacgggga cctgccctgt gcgggtctca gcgctgtgaa aattctcctg
     2821 gctcctaccg ctgtgtgcgg gactgcgatc caggttacca ccctggcccc gagggcacct
     2881 gtgatgacgt ggacgagtgc cgagaatatg gctctgcgat ttgcggcgcc cagcgctgtg
     2941 agaacacccc tggctcctac cgatgcacgc cagcctgcga ccctggctat caacctactc
     3001 cagggggcgg gtgccaggat gtggatgagt gccggaaccg gtctttctgc ggtgcccatg
     3061 ctatgtgcca gaatctgcct ggctccttcc agtgcgtctg tgaccaaggc tacgaggggg
     3121 cacgggacgg gcgtcactgc gtggatgtga atgagtgtga gacactacag ggtgtctgtg
     3181 gctccgcact gtgtgaaaat gttgagggct ccttcctgtg tgtctgcccc accagccctg
     3241 aggagttcga tcccatgact ggacgttgtg ttccccctcg gactcctgca ggcacgttcc
     3301 caggctcgca gccccaagca cctgccagcc ccagtcttcc agccaggcct cccgcccctc
     3361 ccccacctcg aagacccagt cctcccaggc agggtcccgt gagcagtggg cgtcgtgagt
     3421 gctactttga cacggcagct ccagatgcgt gtgacaatat cttggctcgt aacgtgacgt
     3481 ggcaggagtg ctgctgtact gtgggagaag gctggggcag cgggtgccgc atccagcagt
     3541 gcccgggcac ggagacagct gaataccagt cattgtgtcc tcacggccgg ggctacctag
     3601 tgcccagtgg agacctgagt gcccggagag atgtggatga atgccaactc ttccaggacc
     3661 aggtgtgcaa gagcggagtg tgtgtgaaca ctgccccagg ctactcttgc tattgcaaca
     3721 acggcttcta ctatcatgcg cacaggctgg aatgcgttga taatgacgaa tgtgccgacg
     3781 aggagcccgc ttgtgaaggt ggccgctgcg tgaacacggt gggctcttac cactgtacct
     3841 gcgagccccc actggtgctg gacggctcca ggcgacgctg cgtctccaat gagagccaga
     3901 gccttgatga caatctggga gtgtgctggc aggaagtcgg gcctgatctc gtctgcagtc
     3961 gcccacgact agaccggcag gccacctaca cagagtgctg ctgtctctat ggtgaagcct
     4021 ggggtatgga ctgtgctctc tgtcctgccc aggactcaga tgattttgag gctctttgca
     4081 atgtgctgcg cccacctgct tatggcccgc cacgcccggg tggctttgga cttccttatg
     4141 aatatggccc agatataggc ccaccttatc agagtctccc ctatgggcca gatctgtatc
     4201 caccacctgt gctaccctat gacccctacc cacccccacc tggacctttt gctcgccggg
     4261 aggcccctta tggtgccccg cccttcgaaa tgccggactt tgaggatgat ggtgacccct
     4321 atggcgagac tgaggctcct gacccaccaa gccgaggcac tggttggcca tatcggtcca
     4381 gagacacccg tggctccttc ccagagcctg aggaatcctc tgagcgtgga agctatacag
     4441 gagccttgtc tgagccctat gagggcctag aggccgagga gtgtggtatc ctggatggct
     4501 gcgcccacgg ccgctgtgta cgtgttccag aaggcttcac ctgtgattgt ttcgacggct
     4561 accgcctgga catcacccgc atgtcctgcg tcgacatcaa cgagtgtgac gaggctgagg
     4621 caacctcccc actctgcgtc aatgcgcgct gtgtcaacac tgatggttcc ttccgctgta
     4681 tttgccgtcc gggatttgca cccacgcacc aaccacatca ctgtgcgcct gctcgacctc
     4741 gggcctgagc agctgcgtgc gcctagcctc ccattataac tgagcactag gagcttccag
     4801 agtgcaccta gccttcctct agtctgcatg tgtgtgagga tgtcagacag tctcgatgta
     4861 ggatggacgg acacagaggg gtgccttcta tggcaccagt tcatcatgcc tagcccctcc
     4921 caccagtgcc ctgggcctgt cctgggttcc ctgacacatt tcttgccctt ttatacaatt
     4981 ttcaattaaa ccacctattt tgtactttc
//
