LOCUS       NM_022634                438 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus leukocyte specific transcript 1 (Lst1), mRNA.
ACCESSION   NM_022634
VERSION     NM_022634.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Mulcahy H, O'Rourke KP, Adams C, Molloy MG and O'Gara F.
  TITLE     LST1 and NCR3 expression in autoimmune inflammation and in response
            to IFN-gamma, LPS and microbial infection
  JOURNAL   Immunogenetics 57 (12), 893-903 (2006)
   PUBMED   16362817
REFERENCE   2  (bases 1 to 438)
  AUTHORS   Hurt P, Walter L, Sudbrak R, Klages S, Muller I, Shiina T, Inoko H,
            Lehrach H, Gunther E, Reinhardt R and Himmelbauer H.
  TITLE     The genomic sequence and comparative analysis of the rat major
            histocompatibility complex
  JOURNAL   Genome Res 14 (4), 631-639 (2004)
   PUBMED   15060004
REFERENCE   3  (bases 1 to 438)
  AUTHORS   Raghunathan A, Sivakamasundari R, Wolenski J, Poddar R and Weissman
            SM.
  TITLE     Functional analysis of B144/LST1: a gene in the tumor necrosis
            factor cluster that induces formation of long filopodia in
            eukaryotic cells
  JOURNAL   Exp Cell Res 268 (2), 230-244 (2001)
   PUBMED   11478849
REFERENCE   4  (bases 1 to 438)
  AUTHORS   Rollinger-Holzinger I, Eibl B, Pauly M, Griesser U, Hentges F, Auer
            B, Pall G, Schratzberger P, Niederwieser D, Weiss EH and Zwierzina
            H.
  TITLE     LST1: a gene with extensive alternative splicing and
            immunomodulatory function
  JOURNAL   J Immunol 164 (6), 3169-3176 (2000)
   PUBMED   10706707
REFERENCE   5  (bases 1 to 438)
  AUTHORS   Neville MJ and Campbell RD.
  TITLE     A new member of the Ig superfamily and a V-ATPase G subunit are
            among the predicted products of novel genes close to the TNF locus
            in the human MHC
  JOURNAL   J Immunol 162 (8), 4745-4754 (1999)
   PUBMED   10202016
REFERENCE   6  (bases 1 to 438)
  AUTHORS   Middleton PG, Taylor PR, Jackson G, Proctor SJ and Dickinson AM.
  TITLE     Cytokine gene polymorphisms associating with severe acute
            graft-versus-host disease in HLA-identical sibling transplants
  JOURNAL   Blood 92 (10), 3943-3948 (1998)
   PUBMED   9808588
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX883046.1.
            
            On Oct 1, 2009 this sequence version replaced NM_022634.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AI555859.1, AF208230.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06621351, SAMN06680412
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-34                BX883046.1         39462-39495         c
            35-88               BX883046.1         38622-38675         c
            89-190              BX883046.1         38216-38317         c
            191-210             BX883046.1         37812-37831         c
            211-438             BX883046.1         36300-36527         c
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..438
                     /gene="Lst1"
                     /gene_synonym="B144"
                     /note="leukocyte specific transcript 1"
                     /db_xref="GeneID:64569"
                     /db_xref="RGD:620077"
     CDS             1..360
                     /gene="Lst1"
                     /gene_synonym="B144"
                     /note="leucocyte specific transcript 1"
                     /codon_start=1
                     /product="leukocyte-specific transcript 1 protein"
                     /protein_id="NP_072156.2"
                     /db_xref="GeneID:64569"
                     /db_xref="RGD:620077"
                     /translation="MTRMPPCDWGEALKTWGCKDLKFTNTWLLEKQCYLLLGSLVLGG
                     LLLLLVIILFACLCRFYQRVKRLERNAQVSGQELHYASLQKLPASSSDMEGRGEGEGV
                     KEDASTDYACIVLNKPN"
     exon            1..34
                     /gene="Lst1"
                     /gene_synonym="B144"
                     /inference="alignment:Splign:2.1.0"
     exon            35..88
                     /gene="Lst1"
                     /gene_synonym="B144"
                     /inference="alignment:Splign:2.1.0"
     exon            89..190
                     /gene="Lst1"
                     /gene_synonym="B144"
                     /inference="alignment:Splign:2.1.0"
     exon            191..210
                     /gene="Lst1"
                     /gene_synonym="B144"
                     /inference="alignment:Splign:2.1.0"
     exon            211..438
                     /gene="Lst1"
                     /gene_synonym="B144"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgacaagaa tgccaccttg tgactgggga gaggcactca agacatgggg ctgtaaggat
       61 ctgaagttca ccaatacttg gctactagag aaacagtgtt acctgctgtt ggggagcctg
      121 gtactgggag ggctcctcct cctgcttgtc atcatcctgt tcgcctgcct gtgccggttc
      181 tatcagagag tgaagagact agaaagaaac gcccaggtct cggggcagga gctccactac
      241 gcctctctcc agaagctgcc cgcatccagc agtgatatgg aaggcagagg agaaggtgaa
      301 ggcgtaaaag aagacgccag cactgactat gcctgcatcg tcttaaacaa acccaattga
      361 gcgcccccaa aagcctccct cgccctgggt gggtactcag agtcgccccg agttcaccta
      421 gtaaagtctg gttcccca
//
