LOCUS       NM_001013421            2283 bp    mRNA    linear   ROD 04-JUN-2024
DEFINITION  Rattus norvegicus large 60S subunit nuclear export GTPase 1 (Lsg1),
            mRNA.
ACCESSION   NM_001013421 XM_213604
VERSION     NM_001013421.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2283)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   2  (bases 1 to 2283)
  AUTHORS   Reynaud,E.G., Andrade,M.A., Bonneau,F., Ly,T.B., Knop,M.,
            Scheffzek,K. and Pepperkok,R.
  TITLE     Human Lsg1 defines a family of essential GTPases that correlates
            with the evolution of compartmentalization
  JOURNAL   BMC Biol 3, 21 (2005)
   PUBMED   16209721
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2283)
  AUTHORS   Price,M., Lang,M.G., Frank,A.T., Goetting-Minesky,M.P., Patel,S.P.,
            Silviera,M.L., Krady,J.K., Milner,R.J., Ewing,A.G. and Day,J.R.
  TITLE     Seven cDNAs enriched following hippocampal lesion: possible roles
            in neuronal responses to injury
  JOURNAL   Brain Res Mol Brain Res 117 (1), 58-67 (2003)
   PUBMED   14499481
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC091338.1.
            
            On Apr 20, 2005 this sequence version replaced XM_213604.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC091338.1, SRR8487226.52561.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2283
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q22"
     gene            1..2283
                     /gene="Lsg1"
                     /gene_synonym="RGD1309089"
                     /note="large 60S subunit nuclear export GTPase 1"
                     /db_xref="GeneID:288029"
                     /db_xref="RGD:1309089"
     exon            1..114
                     /gene="Lsg1"
                     /gene_synonym="RGD1309089"
                     /inference="alignment:Splign:2.1.0"
     CDS             16..1983
                     /gene="Lsg1"
                     /gene_synonym="RGD1309089"
                     /codon_start=1
                     /product="large subunit GTPase 1 homolog"
                     /protein_id="NP_001013439.1"
                     /db_xref="GeneID:288029"
                     /db_xref="RGD:1309089"
                     /translation="MGRRRAPGGGSLGRVLIRHQTQRSRSHRHTDSWLHTSELNDGYD
                     WGRLNLQSVTEQSSLEDFLATAELAGTEFVAEKLNIKFVPPEARTGLLSFEESQRIKR
                     LHEENRQFLCIPRRPNWDRKTSPEELKQAEKDNFLKWRRQLVRLEEEQKLILTPFERN
                     LDFWRQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKEIDAAKENVILINKADLLT
                     AEQRVAWAVHFEKEGVKVIFWSALAETVHLNGDSKDEVNSVAGEANSSESEDSSLDGN
                     EIPHRDLFLLSEESESDDDDSEYEDCQEDEEEDWQTCSEEDSNPEEGQEEGGCDRDQK
                     EHGPEDSEAQSRASPENSQMSNKSHLVSKQELLELFKKLHTGKKVKDGQLTVGLVGYP
                     NVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVMPSFVSTKAEM
                     ICSGILPIDQMRDHVPPVSLVCQNIPRRVLEATYGINIIKPGEDEDPYRPPTSEELLT
                     AYGCMRGFMTAHGQPDQPRSARYILKDYVRGKLLYCHPPPGKDPVAFQHQHRQLLENK
                     IKGEELRLQPGKTQKAKQVENVVDKTFFHQENVRALTKGVQAVMGYKPGSGLVTAAAA
                     SAENVPGKPWKKHGNRNKKEKSRRLYRHLDV"
     exon            115..241
                     /gene="Lsg1"
                     /gene_synonym="RGD1309089"
                     /inference="alignment:Splign:2.1.0"
     exon            242..362
                     /gene="Lsg1"
                     /gene_synonym="RGD1309089"
                     /inference="alignment:Splign:2.1.0"
     exon            363..449
                     /gene="Lsg1"
                     /gene_synonym="RGD1309089"
                     /inference="alignment:Splign:2.1.0"
     exon            450..536
                     /gene="Lsg1"
                     /gene_synonym="RGD1309089"
                     /inference="alignment:Splign:2.1.0"
     exon            537..597
                     /gene="Lsg1"
                     /gene_synonym="RGD1309089"
                     /inference="alignment:Splign:2.1.0"
     exon            598..774
                     /gene="Lsg1"
                     /gene_synonym="RGD1309089"
                     /inference="alignment:Splign:2.1.0"
     exon            775..1179
                     /gene="Lsg1"
                     /gene_synonym="RGD1309089"
                     /inference="alignment:Splign:2.1.0"
     exon            1180..1281
                     /gene="Lsg1"
                     /gene_synonym="RGD1309089"
                     /inference="alignment:Splign:2.1.0"
     exon            1282..1425
                     /gene="Lsg1"
                     /gene_synonym="RGD1309089"
                     /inference="alignment:Splign:2.1.0"
     exon            1426..1549
                     /gene="Lsg1"
                     /gene_synonym="RGD1309089"
                     /inference="alignment:Splign:2.1.0"
     exon            1550..1629
                     /gene="Lsg1"
                     /gene_synonym="RGD1309089"
                     /inference="alignment:Splign:2.1.0"
     exon            1630..1803
                     /gene="Lsg1"
                     /gene_synonym="RGD1309089"
                     /inference="alignment:Splign:2.1.0"
     exon            1804..2253
                     /gene="Lsg1"
                     /gene_synonym="RGD1309089"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgctgatacg ctgttatggg ccggagaaga gcgccgggtg gtgggtcact gggtcgggta
       61 cttatccggc atcagactca acgaagccgc agtcaccgtc atactgactc ctggctgcat
      121 acgagtgaac tcaatgatgg ttatgattgg ggacgtctga atcttcagtc agtgacggaa
      181 cagagctccc tcgaggactt tcttgcaact gcagaacttg cagggacgga gttcgtggct
      241 gagaagctta atattaagtt tgtgccccct gaggctagaa ctggactgct gtctttcgag
      301 gagagccaga gaattaagag actccatgaa gaaaacagac agttcctgtg tataccaagg
      361 agaccaaatt gggacagaaa aactagccct gaagaactga aacaagcaga gaaagataac
      421 tttctaaaat ggaggcgcca gcttgtccgg ctagaagaag aacagaagtt gatattgact
      481 ccctttgaac ggaatttgga cttctggcgc cagctctgga gggtcattga gagaagtgat
      541 attgtggtcc agatagtaga tgctcggaac ccgctcctgt tcagatgtga ggatttggaa
      601 tgttacgtga aggagataga tgctgccaag gagaatgtga ttctgataaa caaggcagac
      661 ttgttgactg ctgagcagag ggttgcctgg gctgtgcact ttgagaaaga aggtgtgaag
      721 gttatcttct ggtcagcttt ggcagaaacc gttcacctaa atggtgactc taaggatgaa
      781 gtaaacagtg ttgctggaga agccaacagc tctgagtctg aagactccag tttggacggg
      841 aatgaaattc cacacagaga cttgttcttg cttagtgagg agtccgaaag tgacgatgac
      901 gacagtgagt atgaggactg tcaggaggac gaggaggaag attggcagac gtgttctgaa
      961 gaagatagca atcctgagga ggggcaggag gaagggggct gtgatcggga ccagaaggaa
     1021 cacggtcctg aggattctga ggctcagagc agagcatcac cagaaaattc acagatgagc
     1081 aacaagagcc atctggtctc gaagcaggag ttactagagc tcttcaagaa actccacact
     1141 gggaagaagg tgaaagacgg acagctgact gtagggctgg tgggctaccc taatgttggt
     1201 aagagctcaa ccatcaacac catcatgggc aacaagaaag tatcggtgtc tgccacgcca
     1261 ggccacacca agcatttcca gaccctgtac gtggagccag gcctctgtct gtgtgactgc
     1321 cccggcctgg tgatgccatc ttttgtgtct accaaagcag agatgatttg cagtgggatc
     1381 ctccctatcg accagatgag agatcacgtt ccgcctgtat cactagtttg ccagaatatc
     1441 ccgaggcgag ttttagaagc tacctatggc attaacatta taaagcctgg agaagatgaa
     1501 gacccctacc gacctccgac ctcagaagag ctgttgacag cttatggatg catgcgggga
     1561 ttcatgacag cacacggaca gccagaccag cctcggtctg cacgatacat cctgaaggac
     1621 tacgtcagag gtaaacttct gtattgtcac cctcctcctg gaaaagaccc tgtggcattc
     1681 cagcatcaac acaggcaact cctagagaac aaaataaaag gtgaagaact gaggcttcag
     1741 ccaggcaaaa cccaaaaagc caaacaggtt gaaaatgtag tcgacaagac ttttttccat
     1801 caggagaatg tcagagcatt gaccaaaggg gtccaggctg tcatgggtta caagcccggg
     1861 agtggcctgg tgactgcagc tgctgcgagt gctgagaacg tacctgggaa gccctggaaa
     1921 aaacacggta acagaaacaa aaaagagaaa agccgcaggc tctacaggca cctggatgtg
     1981 tgagcttggc tgaagagaaa tggcagctgc actgtgcggg tggacaagga ctgaggccac
     2041 cgctgcctgt gctgcacccc agacaacagc gctgtggact ggaccctgct cttgtggagc
     2101 actcgccccc ggaagtcacc ttcggaagca cctgaggtgg ctacagtagt catgaggtgc
     2161 cccagaagtc tcctgcagga ggatgatgga tgtgtgtata aacatacaga tacataataa
     2221 ctttgaggtt ttgttattaa aattaatttg ccaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     2281 aaa
//
