LOCUS       NM_001013981            2171 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus leucine-rich repeats and WD repeat domain
            containing 1 (Lrwd1), mRNA.
ACCESSION   NM_001013981 XM_006249156 XM_347160
VERSION     NM_001013981.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2171)
  AUTHORS   Bartke,T., Vermeulen,M., Xhemalce,B., Robson,S.C., Mann,M. and
            Kouzarides,T.
  TITLE     Nucleosome-interacting proteins regulated by DNA and histone
            methylation
  JOURNAL   Cell 143 (3), 470-484 (2010)
   PUBMED   21029866
REFERENCE   2  (bases 1 to 2171)
  AUTHORS   Shen,Z., Sathyan,K.M., Geng,Y., Zheng,R., Chakraborty,A.,
            Freeman,B., Wang,F., Prasanth,K.V. and Prasanth,S.G.
  TITLE     A WD-repeat protein stabilizes ORC binding to chromatin
  JOURNAL   Mol Cell 40 (1), 99-111 (2010)
   PUBMED   20932478
REFERENCE   3  (bases 1 to 2171)
  AUTHORS   Ohta,S., Bukowski-Wills,J.C., Sanchez-Pulido,L., Alves Fde,L.,
            Wood,L., Chen,Z.A., Platani,M., Fischer,L., Hudson,D.F.,
            Ponting,C.P., Fukagawa,T., Earnshaw,W.C. and Rappsilber,J.
  TITLE     The protein composition of mitotic chromosomes determined using
            multiclassifier combinatorial proteomics
  JOURNAL   Cell 142 (5), 810-821 (2010)
   PUBMED   20813266
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On or before Mar 29, 2021 this sequence version replaced
            XM_006249156.4, NM_001013981.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360190.599007.1,
                                           SRR26643295.44805.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-199               JAXUCZ010000012.1  26166648-26166846
            200-434             JAXUCZ010000012.1  26168101-26168335
            435-551             JAXUCZ010000012.1  26168753-26168869
            552-692             JAXUCZ010000012.1  26169380-26169520
            693-797             JAXUCZ010000012.1  26169793-26169897
            798-917             JAXUCZ010000012.1  26170310-26170429
            918-1032            JAXUCZ010000012.1  26170509-26170623
            1033-1142           JAXUCZ010000012.1  26171387-26171496
            1143-1350           JAXUCZ010000012.1  26171735-26171942
            1351-1423           JAXUCZ010000012.1  26172418-26172490
            1424-1564           JAXUCZ010000012.1  26172581-26172721
            1565-1656           JAXUCZ010000012.1  26178769-26178860
            1657-1812           JAXUCZ010000012.1  26178993-26179148
            1813-1925           JAXUCZ010000012.1  26179237-26179349
            1926-2171           JAXUCZ010000012.1  26179444-26179689
FEATURES             Location/Qualifiers
     source          1..2171
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q12"
     gene            1..2171
                     /gene="Lrwd1"
                     /note="leucine-rich repeats and WD repeat domain
                     containing 1"
                     /db_xref="GeneID:304396"
                     /db_xref="RGD:1359442"
     exon            1..199
                     /gene="Lrwd1"
                     /inference="alignment:Splign:2.1.0"
     CDS             120..2066
                     /gene="Lrwd1"
                     /codon_start=1
                     /product="leucine-rich repeat and WD repeat-containing
                     protein 1"
                     /protein_id="NP_001014003.2"
                     /db_xref="GeneID:304396"
                     /db_xref="RGD:1359442"
                     /translation="MAPLTPQLLLQRGRPKTDRLGKIQSLNLSGLELLSEHLDPNLLG
                     RLKKLKELDLSNNLLETLPANLGLSHLRILRCTNNQLGDVTTLHQFPELEELSLEGNP
                     FLTVSDNLKVSFLLPKLRKVNGKDTASTCSQVESLDRELTNRVTALWQKFIATVNPEE
                     EANKVQADFMRSAVRDVRYGPESLFEFTQWRVRMIAEELVASGGAQAHEANASVEHPQ
                     AAVGSKLRARKVTKRPDDDEISLPPTKRVRASPPAQTEDSPMDAAGGQAALHLEPLHF
                     LQCHSRNNSPKDLETQLWACAFEPAREEGHSGATSQTVATCGGEAVCVIDCQTGLVLH
                     KYKVPGEEFFSVAWTALTVATQAGHKKRWNMLAAAGLRGMVRLLHVRAGFCCSVIRAH
                     KKAIATLCFSPTHETHLFTASYDKRIILWDIGVPNHDYKFQASQLLTLNCSSVPLRLC
                     PVATCPDSFLLAGCEGGCGCWDVRLDQPQKQRVCEVNFVFSGDSEVSGQRVDGLAFVN
                     EDVVASKGSGQGTIYLWSWSQTWASRGSQSVLPVVILAQLQWSPTSLAYFSLSTCPDK
                     NLVLCGDEEGSVWIYDVEHLLKQPPPLETTLQPPTQILKWPQPVALGQPVTKTMVNTV
                     VANAAFTYLTALTDSNIVSIWKTC"
     exon            200..434
                     /gene="Lrwd1"
                     /inference="alignment:Splign:2.1.0"
     exon            435..551
                     /gene="Lrwd1"
                     /inference="alignment:Splign:2.1.0"
     exon            552..692
                     /gene="Lrwd1"
                     /inference="alignment:Splign:2.1.0"
     exon            693..797
                     /gene="Lrwd1"
                     /inference="alignment:Splign:2.1.0"
     exon            798..917
                     /gene="Lrwd1"
                     /inference="alignment:Splign:2.1.0"
     exon            918..1032
                     /gene="Lrwd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1142
                     /gene="Lrwd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1143..1350
                     /gene="Lrwd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1351..1423
                     /gene="Lrwd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1424..1564
                     /gene="Lrwd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1565..1656
                     /gene="Lrwd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1657..1812
                     /gene="Lrwd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1813..1925
                     /gene="Lrwd1"
                     /inference="alignment:Splign:2.1.0"
     exon            1926..2171
                     /gene="Lrwd1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttccggtcc cctggactct caaagggttt gttgtgcgcc acctcctggg ctccccagca
       61 tccggcctta gtgaccagac ttcgtggagg cgtgggttcg gttgagccct cgaccaccca
      121 tggctcctct cacgccgcag ctgctcctgc aacgtgggcg acccaagacc gacaggctgg
      181 ggaagattca gagtctgaat ctgtcagggc tggagctgct ctcagaacac ttggatccca
      241 atctcctggg acgcctgaag aagctgaagg aacttgacct ctctaacaac ttgctggaaa
      301 cattgcctgc taacctaggc ctgtcccatc tgcgaatcct tcgctgtacc aacaaccagc
      361 taggggacgt caccaccttg caccagttcc cggaacttga ggagctcagt ctggaaggca
      421 accctttcct gacggtcagt gacaacctca aagtctcctt tctcctgccc aagctgcgta
      481 aggtcaatgg caaggacacg gcctccacct gctcacaggt agagagccta gatcgggagc
      541 tgaccaacag ggtcacagcc ctctggcaga agttcatagc cactgtgaac cctgaggagg
      601 aagctaacaa agtgcaggcc gacttcatga ggtccgcagt cagggatgtg cgttacgggc
      661 ccgagtctct cttcgagttc acgcagtggc gggtgcggat gatcgctgag gaactggtgg
      721 cctcaggtgg ggcccaggcc cacgaagcta atgcatcagt ggaacatccc caggcagcag
      781 ttggctccaa gctcagggcc agaaaggtaa caaaacgtcc agatgatgac gaaatcagcc
      841 ttcctcccac caagcgagtg cgggcctccc caccagccca gactgaggac agtcctatgg
      901 atgctgctgg aggccaggcc gccctacacc tggagcccct gcacttcctg cagtgccaca
      961 gcagaaacaa cagccctaag gacctggaga cccagctgtg ggcctgtgcc tttgagccgg
     1021 cccgggagga gggacactcg ggggccacat cccagaccgt ggccacatgt ggcggagaag
     1081 ctgtttgcgt gatagactgc cagacaggcc tcgtgctcca taaatacaag gttccgggcg
     1141 aggagttctt ctcagtggcc tggacagccc tgacggtggc cacccaggca ggccacaaga
     1201 agcgctggaa catgctggca gctgcaggcc ttcggggcat ggtgcggctg ctccatgtgc
     1261 gtgcgggctt ctgctgcagc gtcatcaggg cccataagaa ggccatcgcc accctctgct
     1321 tcagccccac ccatgagact cacctcttca ctgcctccta tgacaaacgg atcatcctct
     1381 gggacattgg ggtgcccaac cacgactaca agttccaggc tagccagctc ctcacgctca
     1441 actgcagttc cgtccctttg cgcctctgtc ctgttgccac ctgcccggac agcttcctgc
     1501 tggctggctg tgagggaggc tgcggctgct gggatgttcg gctagaccag ccccagaagc
     1561 aaagggtgtg tgaggtgaat ttcgtcttct ctggggactc cgaggtgtcg ggacaaagag
     1621 tggatgggct ggcatttgtg aacgaagatg tggtggcctc caaagggagt ggacagggca
     1681 ccatctacct gtggagctgg agccagacat gggcaagccg gggcagccag tcggtgttgc
     1741 ctgtagtcat cctggcccag ctgcagtggt cacccaccag cctggcctac ttctcactga
     1801 gcacctgtcc tgacaaaaac ctcgtgctgt gtggagacga ggaaggcagt gtgtggatct
     1861 acgatgttga acacctactg aagcagccac ctccacttga aacaactctg cagcccccaa
     1921 cacagatcct gaagtggcct cagccagtag cattgggcca accagtgacc aagaccatgg
     1981 taaacacagt cgtggccaat gcagccttca cctacctcac tgctctgacg gactccaaca
     2041 tcgtgtccat ctggaagaca tgctagcccg cccaaggcag tgtgtcagga catggcttat
     2101 tagcttgggc ctagtgctag aggggtttgt accagtgagt attttttatt aaattctact
     2161 gtcggaagtg a
//
