LOCUS       NM_001106387            3842 bp    mRNA    linear   ROD 17-FEB-2024
DEFINITION  Rattus norvegicus leucine rich repeat transmembrane neuronal 3
            (Lrrtm3), mRNA.
ACCESSION   NM_001106387 XM_001074319 XM_228137
VERSION     NM_001106387.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3842)
  AUTHORS   Um,J.W., Choi,T.Y., Kang,H., Cho,Y.S., Choii,G., Uvarov,P.,
            Park,D., Jeong,D., Jeon,S., Lee,D., Kim,H., Lee,S.H., Bae,Y.C.,
            Choi,S.Y., Airaksinen,M.S. and Ko,J.
  TITLE     LRRTM3 Regulates Excitatory Synapse Development through Alternative
            Splicing and Neurexin Binding
  JOURNAL   Cell Rep 14 (4), 808-822 (2016)
   PUBMED   26776509
REFERENCE   2  (bases 1 to 3842)
  AUTHORS   Um,J.W., Pramanik,G., Ko,J.S., Song,M.Y., Lee,D., Kim,H.,
            Park,K.S., Sudhof,T.C., Tabuchi,K. and Ko,J.
  TITLE     Calsyntenins function as synaptogenic adhesion molecules in concert
            with neurexins
  JOURNAL   Cell Rep 6 (6), 1096-1109 (2014)
   PUBMED   24613359
REFERENCE   3  (bases 1 to 3842)
  AUTHORS   Majercak,J., Ray,W.J., Espeseth,A., Simon,A., Shi,X.P., Wolffe,C.,
            Getty,K., Marine,S., Stec,E., Ferrer,M., Strulovici,B., Bartz,S.,
            Gates,A., Xu,M., Huang,Q., Ma,L., Shughrue,P., Burchard,J.,
            Colussi,D., Pietrak,B., Kahana,J., Beher,D., Rosahl,T.,
            Shearman,M., Hazuda,D., Sachs,A.B., Koblan,K.S., Seabrook,G.R. and
            Stone,D.J.
  TITLE     LRRTM3 promotes processing of amyloid-precursor protein by BACE1
            and is a positional candidate gene for late-onset Alzheimer's
            disease
  JOURNAL   Proc Natl Acad Sci U S A 103 (47), 17967-17972 (2006)
   PUBMED   17098871
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JACYVU010000324.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001106387.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760393,
                              SAMEA5760396 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-554               JACYVU010000324.1  20239505-20240058
            555-2089            JACYVU010000324.1  20240384-20241918
            2090-3842           JACYVU010000324.1  20411795-20413547
FEATURES             Location/Qualifiers
     source          1..3842
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p11"
     gene            1..3842
                     /gene="Lrrtm3"
                     /note="leucine rich repeat transmembrane neuronal 3"
                     /db_xref="GeneID:294380"
                     /db_xref="RGD:1304866"
     exon            1..554
                     /gene="Lrrtm3"
                     /inference="alignment:Splign:2.1.0"
     CDS             551..2299
                     /gene="Lrrtm3"
                     /note="leucine-rich repeat transmembrane neuronal protein
                     3"
                     /codon_start=1
                     /product="leucine-rich repeat transmembrane neuronal
                     protein 3 precursor"
                     /protein_id="NP_001099857.1"
                     /db_xref="GeneID:294380"
                     /db_xref="RGD:1304866"
                     /translation="MGFNVIRLLRGSAVAVVLAPTVLLTMLSSAERGCPKGCRCEGKM
                     VYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLNQLTWLYLDHNHISNIDE
                     NAFNGIRRLKELILSSNRISYFLNNTFRPVTNLRNLDLSYNQLHSLGSEQFRGLRKLL
                     SLHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFS
                     KLNLALFPRLVSLQNLYMQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSGPSVFQC
                     VPNLQRLNLDSNKLTFIGQEILDSWISLNDISLAGNIWECSRNICSLVNWLKSFKGLR
                     ENTILCASPKELQGVNVIDAVKNYSICGKSTTTERFDLARALPKPTFKPKLPRPKHES
                     KPPLPPTVGASEPSPETDVDTEHISFHKIIAGSVALFLSVLVILLVMYVSWKRYPASM
                     KQLQQRSLMRRHRKKKRQSLKQMTPGTQEFYVDYKPTNTETSEMLLNGTGPCTYSKSG
                     SRECEIPLSMNVSTFLAYDQPTISYCGVHHELLSHKTFETNAQEDTMESHLETELDLS
                     TITSAGRIGDHKPQLA"
     exon            555..2089
                     /gene="Lrrtm3"
                     /inference="alignment:Splign:2.1.0"
     exon            2090..3842
                     /gene="Lrrtm3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagaatgaca gtctgctgga gtgagctgag cgtgtgcgcg gaaccgggct ctcttgcctt
       61 ctgggctcca acgcagctcc gtggctgaac tgggtgctca ccaccacggg accgccgggc
      121 tatggaatac agatgtggca gcacaggtag ccccacgttg cctagaggaa tacatcatgg
      181 gttttgagaa gaaattatag gagccagttt ttttttttaa cacacacaca cacacacaca
      241 cacacacaca cacacacaca cacacactgt aaagatgcaa agacgtaata tccatgaaga
      301 tcctattacc taggaagact cggatgtttt gctgtgaatg cggtgttggg atttatttgt
      361 tcttggagtg ttctgcatgg ctgataaaga ataatgttcc aaaatcggtc catctcccaa
      421 ggggtccaat ttttcttcct gggtgtcagc gagccctgac tcactacact gcagctgaca
      481 ggggctgtca tgcaggcggc ccctaagcca aagcaaaaga cctaaggacg acctttgaac
      541 aatacaaagg atgggtttca atgtaattag gctactgcgc ggatcagctg tagcggtggt
      601 cctagccccc actgtcttac tgactatgct ttcttctgct gaaagaggat gccctaaggg
      661 ttgtaggtgc gaaggcaaaa tggtctactg tgagtctcag aaactgcagg agataccctc
      721 aagtatatca gccggatgct tgggtttatc ccttcgctac aacagcctcc aaaaacttaa
      781 gtataatcaa tttaaagggc tcaaccagct cacctggctc taccttgacc ataaccatat
      841 cagcaatatc gacgagaatg ctttcaatgg gatacgcaga ctcaaagagt tgattctgag
      901 ttccaacaga atctcctatt tccttaacaa caccttcaga cctgtgacca atctacggaa
      961 cttggatctg tcctataatc agctccattc tctgggatct gaacagttcc ggggcttgag
     1021 gaagctgctc agtttacacc tccgctccaa ctcactgaga accatcccgg tgcggatttt
     1081 ccaagactgt cgcaacctgg aacttctgga cctgggctat aacaggatcc gaagtttagc
     1141 caggaatgtc tttgctggca tgatcagact caaagagctt cacctggagc acaatcaatt
     1201 ttccaagctc aacctggccc ttttcccaag gttggtgagc cttcagaact tgtacatgca
     1261 gtggaataaa atcagtgtca taggacaaac catgtcctgg acttggagct ccttacagag
     1321 acttgacctg tcgggtaatg agatcgaagc cttcagtgga cccagtgtct tccagtgtgt
     1381 ccccaatctg caacgcctca acctggattc caacaagctc acatttattg gtcaagagat
     1441 tctggattct tggatctctc tcaatgacat cagccttgct gggaatatat gggaatgcag
     1501 caggaatatc tgctccctgg tgaactggct gaaaagtttt aaaggtctga gagagaatac
     1561 aattctctgc gccagtccca aagagctgca gggggttaac gtgatcgatg cagtgaagaa
     1621 ctacagcatc tgtggcaaga gcactaccac agagaggttt gacctggcca gggccctccc
     1681 caaacccacg tttaagccca agctccccag gcctaagcac gagagcaagc ctccgctgcc
     1741 ccccacggtg ggagctagcg agcccagccc agagacagat gtggacacgg agcacatctc
     1801 cttccataag atcatcgcgg gcagcgtggc ccttttcctg tcggtgctgg tcatcctctt
     1861 ggttatgtac gtgtcctgga agcggtaccc cgccagcatg aagcagctgc agcagcgctc
     1921 cctcatgcga aggcaccgga agaagaaacg gcaatcgctc aagcaaatga ctccaggcac
     1981 ccaggaattt tatgtagatt ataaacccac caacacggag accagcgaga tgctgctgaa
     2041 cggaaccgga ccctgcacct atagcaaatc aggctccagg gaatgtgaga tacctttatc
     2101 aatgaatgtg tcaacttttc tggcatacga ccagcccaca ataagttact gtggggtcca
     2161 tcatgaactc ctctcccata agacctttga aacgaatgca caggaagaca cgatggaaag
     2221 ccacctagag actgagctgg acttgagcac aatcacgtca gctggccgca tcggcgacca
     2281 taaaccacag ctggcctgac ccagctggcc tgacccagct gaacggtagc ccaggcttgc
     2341 cacccaacta taacctcaac tacagaaaga ggagactctg ttcattgcaa ttctcgaata
     2401 caaaacaaaa acaaaactcc cctgttcaaa taaacaaaat tttaagattg gttcatgaaa
     2461 taaaagagga catgaattgt ttcaagtcta cactttgtaa ctagctaagt tgtgcagtat
     2521 ttttttgact ttaacagaga acgaccctga aaaaaaatca ttttttttct ccaaaactca
     2581 tcctacctac atgtaaaaat tgtacagcgc taatgtattt ttcatattat aaagtttcaa
     2641 ttctaggaac aactggtatg tacagtactg taatttaatt gatgctttac tttacacctt
     2701 tcagtttcta aaattttaaa ttaaccaaca ttattttctt gtgttcttga gagttacttg
     2761 gttttgtggg ggctgttttg ttactgcatt tgtgcccaga aaccttgact ctgaaatctg
     2821 tgctgtgcaa acaacgcacg atttttatca ttaccacgct tactgcatag aattttatct
     2881 acttgttcca gaaataatac attaaccaaa agaaggtttt aattgttcag acgtgtaaga
     2941 tgttcttcaa ttacatagac aggtctttct tataaacgga aaaaaatcag atttttttta
     3001 acagttcttc taagactcaa ctgttgcctt gaattacagc ctagttttta agcagtgaaa
     3061 tgtaatgata aagagggata ttttaacaaa atatttccga atgaatgact cattatttca
     3121 tccttttgaa taaccattgt taagggtagg ggaaagcatg gaccaaacat cactggaaac
     3181 aaaggttgta accatagcaa cagacttctt ctatacactt caaaggtgca gctaacatga
     3241 caaagaaaaa cccctgttac atctcctcct cgttgtcagg ccaaggtggg aggatatggc
     3301 ataattgtac agtagcaatt ttttctctta attaactcaa agtggtttat ctaaaaataa
     3361 ccacaagtca gttcaaactg cctggttctt aaggcaagtt ttcatttgga aggcgaaact
     3421 atatttggga acatcttgta agaaaaatac agattttttt tctttactgt gtgccacacc
     3481 taagaaagaa ctttatacat ctggttcttt gaggatagat gtgctggagt agagaaaagt
     3541 cactgcagaa tagaccatac cattgttcgt gttgttgttc atttgggagt ttaactacaa
     3601 gttatctaaa acaataacca agagctgttg gccctcaatc taacttacat attggttatt
     3661 cgattgtgtt ttaaactgaa ttcaaatcag ataaagaaaa cctgttcttt tctccagcta
     3721 aaatgacaac ttgtttctgt cgtctagctg acaggttatt attggaaata tcaagtttgt
     3781 tcatggtaat cacacattcc ctttttgttt ttgctttgtt tgtttttaaa gaatatttag
     3841 at
//
