LOCUS       XM_216085               4805 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus leucine-rich repeats and death domain
            containing 1 (Lrrd1), transcript variant X1, mRNA.
ACCESSION   XM_216085
VERSION     XM_216085.9
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_216085.10.
            
            On Jan 21, 2021 this sequence version replaced XM_216085.8.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4805
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4805
                     /gene="Lrrd1"
                     /note="leucine-rich repeats and death domain containing 1;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 1 EST, 4 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     3 samples with support for all annotated introns"
                     /db_xref="GeneID:296836"
                     /db_xref="RGD:1562785"
     CDS             428..2995
                     /gene="Lrrd1"
                     /codon_start=1
                     /product="leucine-rich repeat and death domain-containing
                     protein 1 isoform X1"
                     /protein_id="XP_216085.3"
                     /db_xref="GeneID:296836"
                     /db_xref="RGD:1562785"
                     /translation="MSEDGSNVEPEGLTRSESLEEPEFIDEISDPSNETSPHSGNTDF
                     NQIYESNSSENTEQPSASSTSQLNGNEETNIEIPFSDTNIEEVIPLSNSESPQSSESS
                     ETNEAEEYHPVKFPIGRKFRGRTFNGHHKGFDMESDTFTVHLDAKGLQEFPVDIVKVK
                     YVKYLYLDKNQIKTFQGADPGDLLGLETLSLQENGLSSIPQEIQLFHNLKVLNASYNE
                     ISHIPKELLQLGNMRQLFLNSNHIESLPSGLENLRYLETLSLGKNRLTHIPDSLCGLK
                     NLKTLNLEYNQLTIFSKSLCFLPKLVSLNLTGNMIGSLPKEVRELKNLENLLMNHNKL
                     TFLAVEIFQLLKIKELHLADNKLEAISPKIENFKELRLLNLDNNLLQSLPKKISHCVN
                     LESLTLSDNNLEELPKKIRKLKNLRQLHANRNKMIKMAEEISHLSKIHSLEFSGNQIT
                     HVPIEIKNCKEITRVELNYNNIMYFPVGLCALQSLDYLSFNGNYISEIPVDLSFSKQL
                     LHLELNKNKITIFSEHLCSLTNLEYLDLAKNQIRKIPHCISAMLSLHVLILSDNKFEI
                     FPKELCSLKNLQLLDISENQLHKIPSEISKLKKIQKLNLSNNNFTHFPAELCQLQTLE
                     DLNISQISGKKLTRLPEEVSRMTQLKALNISNNAIKEIPRNIGELRNLITFHASNNQI
                     NSLPSSFLSLNVLQSLDLGGNNLTDLPSAIYKLSSLKEINFDDNPLLRPPMEICKGKQ
                     MHTITCYLQRADDRDEKILEKIFHIVANNITETKFEFLQQKLHMARSENSVPVKTTTP
                     LNEGIYQALLKWKTEKRVSFTAIALKDQLFRALNMIGAYDIMDKITALNLYTSAIKL"
ORIGIN      
        1 ttgcgaccaa agcgagctca taaacgccag agggaggcgg gacacaactg agcctgcgca
       61 acctccatcg ccacaatcac ggacattcgc ctcgcgggct cgcctcctgc aggcttccga
      121 gcgccacagg gaggctctgc gagactgatc taaggactgc taagttcttt acttgcctcc
      181 atcccctcgc agcaccagca ccttcacgcc cccggcccac agctcctagt gtttgcgttc
      241 tgtcccgtgc tgctttagcc gccaaagctc agcgatcttc tccccacacc ggtcgaagca
      301 atttgttaat gtcactaaag tcttgtagtt acttggatgt ccacatcgtt cagataggtt
      361 caaaggggaa aaacacacga aaaagtaaag ttataatctg ttcgtacaag agttacccgt
      421 aaataagatg tctgaagatg ggagtaatgt ggagcctgaa ggactcacta gatctgagtc
      481 actggaggag cctgaattta ttgatgaaat atcagatccc tcgaatgaaa cctcacctca
      541 ctctggaaat acagatttca accagattta tgaatcaaat tcttcagaga acacagaaca
      601 gccatcagct tcctccacaa gccagcttaa tggaaatgaa gagacaaaca tagaaattcc
      661 attttcggac actaacatag aagaggtcat cccactgtca aactcagaaa gtccgcagag
      721 ctctgagtca tcagagacta acgaggctga agaatatcac ccagtcaaat tcccaattgg
      781 gaggaaattt agaggacgaa cctttaatgg acaccacaaa ggatttgaca tggagtctga
      841 tacctttaca gttcatcttg atgccaaggg tttacaagaa ttccctgtag acattgttaa
      901 agtcaaatat gtaaaatatt tatatttaga taagaatcaa ataaaaactt tccaaggggc
      961 agatccaggt gatctgctag gacttgaaac tctgtccttg caagaaaatg gattgtcatc
     1021 gattccccag gaaattcagt tgtttcacaa tttaaaggta ctaaatgcca gttacaacga
     1081 gatatcacat atccctaaag aactattaca actggggaat atgaggcaac tcttcttaaa
     1141 tagtaatcat attgaatctt taccttctgg cttagaaaat cttagatatt tggaaacttt
     1201 aagtttgggt aaaaataggt taacacatat accagactct ttgtgtggtt tgaaaaattt
     1261 gaaaactctc aatctggaat ataaccaatt aacaatattt tctaaatcgc tatgcttcct
     1321 tccaaaactc gtttccctaa accttactgg aaacatgata ggcagtttgc caaaagaagt
     1381 tagggaactg aaaaatttag aaaacctttt aatgaatcac aataaactta cttttttggc
     1441 tgtggagata tttcagttgc tcaaaataaa agaacttcat ctagctgaca ataaattgga
     1501 agccatttca cccaaaattg agaatttcaa ggaactcagg ctgctcaacc ttgataacaa
     1561 tttattgcaa agcttaccaa agaaaatttc ccactgcgta aacttggaat ctcttactct
     1621 cagtgataat aatttagaag aacttcctaa gaaaatccga aagcttaaaa atctgagaca
     1681 actccatgca aacagaaata aaatgataaa aatggctgaa gaaatctcac atcttagcaa
     1741 gatacacagc ctagagtttt caggcaatca aatcacacat gttcctattg aaataaaaaa
     1801 ctgcaaagaa ataaccagag ttgaattgaa ttataacaac ataatgtatt tcccagtggg
     1861 gttgtgtgcc ttacagtcac ttgactactt gagttttaat ggaaattata tttcagaaat
     1921 ccctgtggat ttgtcattca gtaagcagct gcttcattta gagttgaata aaaacaagat
     1981 caccatattt tcagaacatt tatgttctct cactaatctt gaatacctgg atcttgctaa
     2041 aaatcaaata aggaaaattc ctcactgtat ctctgctatg ttatcactcc atgttctcat
     2101 tctgtctgat aataagttcg agattttccc aaaggaactg tgttctttaa aaaacttgca
     2161 actgcttgat atttcagaaa atcaattaca taagatacct tcagaaatat ccaaactgaa
     2221 aaagatccag aagttaaact tgtcaaacaa taatttcaca cattttcctg ctgaactgtg
     2281 ccaacttcaa actctggagg acctgaatat aagtcagata agtgggaaaa agttaacaag
     2341 acttccagaa gaggtgtctc gtatgactca actcaaagcc ctcaatattt cgaacaatgc
     2401 aatcaaagag attccaagaa atatagggga gctgagaaat ctcattactt ttcatgcaag
     2461 caacaatcaa ataaattctc ttccatcgtc ctttctgtct ttaaacgttc tacagagcct
     2521 agatcttgga ggaaacaatc tgacagattt gcccagtgct atctacaaac tttcatctct
     2581 gaaagagata aattttgatg acaatccttt gctgagacct ccaatggaaa tctgtaaagg
     2641 aaaacagatg catacaatca cttgctatct ccagagagca gatgacagag acgagaaaat
     2701 cttagagaag atattccaca tagttgccaa caatatcact gaaacaaaat ttgaattttt
     2761 gcaacaaaaa ctacacatgg caaggtcaga aaacagcgtc cctgtaaaga ccactactcc
     2821 attaaatgaa ggaatctacc aggcattact taagtggaaa acagagaaga gggtatcatt
     2881 cacagctatt gccttaaaag accaactttt tcgggcacta aatatgatag gtgcctatga
     2941 tataatggac aagatcacag cgttgaacct ttatacaagc gccatcaaac tgtagcgtaa
     3001 gggatctgaa atagaagctg aaaccttatc acacacttac agaatggaaa tctgacctct
     3061 gggctgtttc atttttgctg atacaaggaa attatttgca tatcctctct ctatctcttt
     3121 tgtttcctag tagtgtgtgg gtgtgtgggt gtgcgtgcaa ggacgtgtgt gtgagtgtga
     3181 atgtgacaca gtcggcatgc ggaagtgaaa ggaaaacttc caggtgtcaa tgttctcctt
     3241 ccttccatca tgtggtcctg agactgaagt gaggtcatca ggcttagcct gcgtcatgtc
     3301 tctttttatt tatcgctaag agatgctgtc aatgtttgtc taccattcta gttttatcca
     3361 aacaaaaata tcacagacat ggcttcacat atttttttgt tgcattggta atgctactga
     3421 acttgaaaac aattctatta ggattatttt attatagtac tcttacacgt caagatgtat
     3481 gggtaatagg ttggtggtga tttccattga gttgagaaag aagagaagct cctgacttat
     3541 aatgaaaatg gtttaccatc tctggttccc ctcatttaga agtaggatgt cttcattatc
     3601 cataaaatag agccagggag agtattactt cagctttgcg tcctcatggg tatgatgtca
     3661 taggtagctt ttcccttctg tcctgtattt tccctttctt ctgttatcag aaattctcat
     3721 tcatgaagaa tctattgcac atattttaca caggtctgtc cttgttgtat gtaacctact
     3781 ttcctccttt ttgaatccac taatgttaag gtctggttgt ctttggcaat ccgtttcagt
     3841 taagtcatgt cagtgagttt ccttgggatt tcctggagtg cttcctggga aggtgcactc
     3901 ctttcatcgg gagattatgc atctgggaac atgctgccat ctactcagtg ttacatagag
     3961 aaactcagaa ccctaattac attgtttgga cttcaaatcc taacatacct gaaacttact
     4021 gtgtttccaa actcccactt taactcactt aaattgccat gactcgaata gggttctgta
     4081 actttgaata aaaagagacc aaatttaggt aattaataat attgtagacg cactgcggtt
     4141 aaaatgtcat atgagaacta attatagaac aaatttatct tcctggttag agtttgtgta
     4201 tattttttca gttgtaaaat gttttctaaa atattggttc aacagaaaaa aacctatatc
     4261 tctaatctta aaatattttt ccaatattac taccctgcaa atatattaac ttagtgtcag
     4321 ctgctgtttc atatacctcc ttggaagtgg ggatattttc acagaatagt aaagtaaaaa
     4381 ggaccttgcc gaattaccta ttgatttcag atcaccctgc aacctgaaca aaattagacc
     4441 tagaaatcat gaatgctatg agtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg
     4501 agagagagag agagagagag agagagagag agagagagag agagagaggg agagagaggg
     4561 agagagagag agagagagag aagacggaga gaggagagga gagagggagt gagtgaggga
     4621 gaggaggagg gggacggaga gaagagaaga ttggataaca tcatcagaac aatgaaagta
     4681 cttttcctta gtatggaaga cccagaaatg aacccacaca cctatggtca cttggttttt
     4741 gacaaaggag ccaaaaccat caaatggaaa aaaaatatca ttttcaacaa atggtgctgg
     4801 ttcaa
//
