LOCUS       NM_001100645            3532 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus leucine rich repeat and coiled-coil centrosomal
            protein 1 (Lrrcc1), mRNA.
ACCESSION   NM_001100645 XM_001054030 XM_342209
VERSION     NM_001100645.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3532)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   2  (bases 1 to 3532)
  AUTHORS   Xiao,H.S., Huang,Q.H., Zhang,F.X., Bao,L., Lu,Y.J., Guo,C.,
            Yang,L., Huang,W.J., Fu,G., Xu,S.H., Cheng,X.P., Yan,Q., Zhu,Z.D.,
            Zhang,X., Chen,Z., Han,Z.G. and Zhang,X.
  TITLE     Identification of gene expression profile of dorsal root ganglion
            in the rat peripheral axotomy model of neuropathic pain
  JOURNAL   Proc Natl Acad Sci U S A 99 (12), 8360-8365 (2002)
   PUBMED   12060780
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Feb 11, 2021 this sequence version replaced NM_001100645.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data from several strains because no single
            transcript was available for the full length of the gene. The
            extent of this transcript is supported by transcript alignments and
            orthologous data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR21887621.229095.1,
                                           SRR26643293.11076.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-144               JAXUCZ010000002.1  88781292-88781435   c
            145-350             JAXUCZ010000002.1  88779049-88779254   c
            351-416             JAXUCZ010000002.1  88778721-88778786   c
            417-584             JAXUCZ010000002.1  88777888-88778055   c
            585-760             JAXUCZ010000002.1  88775355-88775530   c
            761-961             JAXUCZ010000002.1  88775056-88775256   c
            962-1158            JAXUCZ010000002.1  88773712-88773908   c
            1159-1306           JAXUCZ010000002.1  88772035-88772182   c
            1307-1455           JAXUCZ010000002.1  88771194-88771342   c
            1456-1660           JAXUCZ010000002.1  88767015-88767219   c
            1661-1800           JAXUCZ010000002.1  88765954-88766093   c
            1801-2002           JAXUCZ010000002.1  88763012-88763213   c
            2003-2188           JAXUCZ010000002.1  88760458-88760643   c
            2189-2363           JAXUCZ010000002.1  88759415-88759589   c
            2364-2527           JAXUCZ010000002.1  88758410-88758573   c
            2528-2736           JAXUCZ010000002.1  88757396-88757604   c
            2737-2874           JAXUCZ010000002.1  88757163-88757300   c
            2875-3010           JAXUCZ010000002.1  88756459-88756594   c
            3011-3532           JAXUCZ010000002.1  88753300-88753821   c
FEATURES             Location/Qualifiers
     source          1..3532
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q23"
     gene            1..3532
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /note="leucine rich repeat and coiled-coil centrosomal
                     protein 1"
                     /db_xref="GeneID:266808"
                     /db_xref="RGD:628722"
     exon            1..144
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..3133
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /note="sodium channel associated protein 2, Sap2; leucine
                     rich repeat and coiled-coil domain containing 1"
                     /codon_start=1
                     /product="leucine-rich repeat and coiled-coil
                     domain-containing protein 1"
                     /protein_id="NP_001094115.3"
                     /db_xref="GeneID:266808"
                     /db_xref="RGD:628722"
                     /translation="MEAAACTEIEPEDGDSSCEDVCFMDKGLHSISELSLDSSLHAIN
                     LHCNNISKITSIDHIWNLRHLDLSSNQISQIEGLNTLTKLCTLNLSCNLITRVEGLEA
                     LVNLTRLNLSYNHISDLSGLIPLHGLKYKLRYIDLHSNYIDSIHHLLQCTVGLHFLTN
                     LILEKDGEGNPICLVPGYRAIILQTLPQLRILDCKNIFGEPVSLEEMNSSHLQCFEGL
                     LDNLVSSDSPLNISEDEVVDNMSAPPIDVLPPLEEFTSTPEENVLTSLLSACSSEPEK
                     INHENNFQNEMKLQKLDDQILQLLNETNNSLIDNVPEKDLRPKRDTDITSESDYGNRK
                     ECSRKVSRRTKIPYYTRTIQSIKHHNKNNGAFVSCNRKMRQPYLRDLYVRSSLVNCNN
                     LREVDEQKNGMIKVDKSASNDNTYRSLVEQLDQEREMRWKAEQTEKKLMDYIDELHKQ
                     ANEKKDVHSQAIITTDRLKDAIFKERHCKAQLEVIVHRLQNEIKKLTIELMKARDQQE
                     DHIRHLRTLERALEKMEKQKAQQQQAQMRLIQEVELKASAADREINLLRTSLRQEKEQ
                     VQQLHDLLALKEQEHRQEIETREFFNDAEFQDALTKRLSKEERKHEQEVKEYQEKINI
                     LNQQYLDLENEFRIALTVEARRFKDVQDGFEDVATELAKSKHALIWAQRKENESSSLI
                     KDLTSMVKEQKTKLSEVCKLKQEAAANLQNQINTLEILIEDDKQKSIQIELLKHEKNQ
                     LISELAAKESLIYGLRTERKVWGHELAYQGTSLSQSRGKLEAQIESLCRENESLRKTH
                     ESDCDALRIKCKIIEDQTETIRKLKDGLQEKDGQIKMLQEQITIIEKCSQEQLNEKTS
                     QLDSIVEKLERHNERKEKLKQQLKAKELELEEIRKAYSTLNKKWHDKGELLSNLETQV
                     KEVKEKFENKEKKLRAERDRSLELQKDAVEKLQNMDDAFKRQVDAIVEAHQTEITQLA
                     NEKQRYIECANLKVQQIEDEMRGLLEETCKNKKLMEEKIKQLACAISDIQKEM"
     exon            145..350
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /inference="alignment:Splign:2.1.0"
     exon            351..416
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /inference="alignment:Splign:2.1.0"
     exon            417..584
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /inference="alignment:Splign:2.1.0"
     exon            585..760
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /inference="alignment:Splign:2.1.0"
     exon            761..961
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /inference="alignment:Splign:2.1.0"
     exon            962..1158
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /inference="alignment:Splign:2.1.0"
     exon            1159..1306
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /inference="alignment:Splign:2.1.0"
     exon            1307..1455
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /inference="alignment:Splign:2.1.0"
     exon            1456..1660
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /inference="alignment:Splign:2.1.0"
     exon            1661..1800
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /inference="alignment:Splign:2.1.0"
     exon            1801..2002
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /inference="alignment:Splign:2.1.0"
     exon            2003..2188
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /inference="alignment:Splign:2.1.0"
     exon            2189..2363
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /inference="alignment:Splign:2.1.0"
     exon            2364..2527
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /inference="alignment:Splign:2.1.0"
     exon            2528..2736
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /inference="alignment:Splign:2.1.0"
     exon            2737..2874
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /inference="alignment:Splign:2.1.0"
     exon            2875..3010
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /inference="alignment:Splign:2.1.0"
     exon            3011..3532
                     /gene="Lrrcc1"
                     /gene_synonym="Sap2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagctgggac ccagcgctgg gcgccaatta acacccactc cccgtcgctg gtaccatgga
       61 ggcggcggca tgtacggaaa tcgaaccgga ggatggcgac agcagctgcg aggatgtgtg
      121 tttcatggac aaaggcctgc acagtatatc agagttatct ttagattcat cccttcatgc
      181 catcaatttg cattgtaata acatctccaa gatcacatcc attgaccaca tttggaacct
      241 gcgacatttg gatctgtcat ctaatcaaat aagtcaaatt gaaggcctga acacactaac
      301 aaagctatgc actttaaact tgtcctgcaa tttgatcaca agagtggaag gactcgaagc
      361 actggtaaat ctgactagac tgaatttgtc ttataatcac ataagtgatc tcagcgggtt
      421 gatccccctt catggactaa agtataaact tagatatatt gacctacata gtaattatat
      481 agatagcatc catcacttac ttcagtgtac agtaggatta cacttcctaa ccaatcttat
      541 tttagagaaa gatggagaag gtaatcctat ctgtcttgta ccagggtacc gagcaatcat
      601 tctccagact ttaccacagc tgagaatctt agactgcaag aatatatttg gtgagccagt
      661 aagtttggaa gagatgaact catcgcacct acagtgcttc gaaggtcttc tggataattt
      721 agtttcttct gattcccccc tgaatataag tgaagatgag gtcgttgata atatgtcagc
      781 accaccaata gatgtgttgc ctcctttgga ggaatttaca agtacaccag aagaaaatgt
      841 tttgacctca cttttatctg cgtgttcatc tgaaccagaa aaaattaatc atgaaaacaa
      901 ttttcaaaat gagatgaaac ttcagaaatt agatgatcaa atcctacagc tgctcaacga
      961 aactaataat tccttaatag ataatgttcc tgagaaagac ctcagaccaa aaagagacac
     1021 agatataact tctgaaagtg actatggaaa cagaaaagag tgcagcagaa aagtttccag
     1081 aagaacaaaa atcccatact ataccagaac tattcaaagt attaagcacc acaataaaaa
     1141 caatggtgct tttgtaagtt gtaatcgtaa aatgagacag ccttacttga gagatttata
     1201 tgtaagatca tcgttagtaa actgtaataa cttaagagaa gtagatgagc agaagaatgg
     1261 catgattaaa gtagacaaaa gtgcttcgaa cgacaacact taccggtccc ttgtggaaca
     1321 gttagaccaa gagagagaga tgaggtggaa agcggagcaa acggaaaaga aacttatgga
     1381 ctatattgat gagctacata agcaagcaaa tgagaagaaa gatgttcaca gccaggcaat
     1441 cattaccaca gataggctaa aggatgctat tttcaaggag aggcattgca aggctcaact
     1501 tgaagttata gttcacagac ttcaaaatga aattaaaaaa ctaactattg aattaatgaa
     1561 agcacgagat caacaggaag atcacatcag acacttgaga actctggaaa gagcattgga
     1621 aaaaatggag aagcaaaaag cacagcagca gcaggcacag atgagactga tccaagaggt
     1681 ggagctcaaa gcctcggctg ctgatcgaga aataaactta cttcgaacct ctcttcgcca
     1741 agaaaaggag caagtacaac aacttcatga ccttctggca ctgaaagaac aggagcacag
     1801 acaagaaatt gaaactcggg agtttttcaa tgatgctgag ttccaggatg cattaactaa
     1861 acgattgtcc aaagaagaaa gaaaacatga gcaagaagta aaagaatacc aagaaaaaat
     1921 taatatatta aaccagcagt atttggattt agaaaatgaa ttccgtattg ctttaactgt
     1981 tgaagctaga agatttaaag atgttcaaga tggctttgaa gatgtcgcaa ctgaattagc
     2041 gaagagtaaa catgctctta tttgggctca acgtaaagaa aatgagtctt cctctttaat
     2101 taaagatctg acctctatgg tgaaggaaca aaagacaaaa ctctcagaag tctgcaaatt
     2161 gaagcaggaa gcagcagcaa atttacagaa tcaaatcaac actcttgaaa ttttgattga
     2221 agatgacaag caaaagagca ttcaaataga acttctcaaa catgagaaaa accagctcat
     2281 ttctgagctg gcagccaaag agtcgctgat ttatggctta aggaccgaga gaaaagtatg
     2341 gggacacgaa ctggcatacc agggcacatc actatcccag agtcgtggga aactagaagc
     2401 tcaaatagaa agtttatgca gagaaaatga gtctctgaga aaaacccatg aaagtgactg
     2461 tgatgccttg agaataaagt gcaagatcat cgaggatcaa actgaaacca tccggaaact
     2521 aaaagatggt ttacaagaaa aagatgggca aatcaaaatg ctacaagaac aaatcaccat
     2581 catagaaaaa tgttctcaag agcaacttaa tgaaaagact tcacaactag attctatagt
     2641 tgagaaactg gagagacata atgaaagaaa ggaaaaacta aagcaacagt tgaaggcaaa
     2701 ggaattagaa cttgaagaaa tcagaaaagc ttacagcaca ctaaataaga aatggcatga
     2761 caaaggagaa ctactctcta atcttgaaac acaagtaaaa gaagtaaaag aaaaatttga
     2821 aaacaaggaa aagaaactga gagcagagag agacagaagc cttgagctac aaaaggatgc
     2881 agtagaaaag cttcagaaca tggatgatgc ctttaaaaga caagttgatg caattgttga
     2941 agcacatcaa actgaaataa cacaactagc aaacgagaag cagagatata ttgagtgtgc
     3001 aaatttaaag gttcaacaga ttgaagacga aatgcgagga cttctggaag aaacatgcaa
     3061 gaacaaaaaa ttgatggagg aaaaaattaa gcaacttgct tgtgctataa gtgacataca
     3121 gaaagaaatg tgatgtttag ttgaaatgga ccaacagacc tattgtaaaa atgattaaat
     3181 attgtaacag tagtatctgc tatgtctctt tctacacatt tcattatgaa tatattttaa
     3241 gagacttgat gaaatattgt atatgtgggg tttttataat aaagcattat caattatgtt
     3301 tattagatgg acctatcata ataactagac ttaaagcact tttcttgtct ctgtgctgta
     3361 ccttgttgat aattactcac ttacagattt gtaaaggaat gttacaattt gactatagga
     3421 aagatacgaa aataatcatt gttgagttgt tctaatgcag aactacttgt atttacaggt
     3481 tatcctttag taaatgcaac tcccttcttc taaagtgtct gtaagatgta ag
//
