LOCUS       NM_001107753            5500 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus leucine rich repeat containing 4C (Lrrc4c), mRNA.
ACCESSION   NM_001107753 XM_001079006 XM_230311
VERSION     NM_001107753.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5500)
  AUTHORS   Matsukawa,H., Akiyoshi-Nishimura,S., Zhang,Q., Lujan,R.,
            Yamaguchi,K., Goto,H., Yaguchi,K., Hashikawa,T., Sano,C.,
            Shigemoto,R., Nakashiba,T. and Itohara,S.
  TITLE     Netrin-G/NGL complexes encode functional synaptic diversification
  JOURNAL   J Neurosci 34 (47), 15779-15792 (2014)
   PUBMED   25411505
REFERENCE   2  (bases 1 to 5500)
  AUTHORS   Song,Y.S., Lee,H.J., Prosselkov,P., Itohara,S. and Kim,E.
  TITLE     Trans-induced cis interaction in the tripartite NGL-1, netrin-G1
            and LAR adhesion complex promotes development of excitatory
            synapses
  JOURNAL   J Cell Sci 126 (Pt 21), 4926-4938 (2013)
   PUBMED   23986473
REFERENCE   3  (bases 1 to 5500)
  AUTHORS   Zhang,J., Zhang,J., Zhou,Y., Wu,Y.J., Ma,L., Wang,R.J., Huang,S.Q.,
            Gao,R.R., Liu,L.H., Shao,Z.H., Shi,H.J., Cheng,L.M. and Yu,L.
  TITLE     Novel cerebellum-enriched miR-592 may play a role in neural
            progenitor cell differentiation and neuronal maturation through
            regulating Lrrc4c and Nfasc in rat
  JOURNAL   Curr Mol Med 13 (9), 1432-1445 (2013)
   PUBMED   23971736
  REMARK    GeneRIF: miR-592 may play a role in neural progenitor cell
            differentiation and neuronal maturation through regulating Lrrc4c
            and Nfasc in rat.
REFERENCE   4  (bases 1 to 5500)
  AUTHORS   Bohm,D., Keller,K., Pieter,J., Boehm,N., Wolters,D., Siggelkow,W.,
            Lebrecht,A., Schmidt,M., Kolbl,H., Pfeiffer,N. and Grus,F.H.
  TITLE     Comparison of tear protein levels in breast cancer patients and
            healthy controls using a de novo proteomic approach
  JOURNAL   Oncol Rep 28 (2), 429-438 (2012)
   PUBMED   22664934
REFERENCE   5  (bases 1 to 5500)
  AUTHORS   Lin,J.C., Ho,W.H., Gurney,A. and Rosenthal,A.
  TITLE     The netrin-G1 ligand NGL-1 promotes the outgrowth of
            thalamocortical axons
  JOURNAL   Nat Neurosci 6 (12), 1270-1276 (2003)
   PUBMED   14595443
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Aug 4, 2021 this sequence version replaced NM_001107753.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            CDS exon combination :: SRR26360176.2443410.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA5760393, SAMN12840130 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-418               JAXUCZ010000003.1  102760750-102761167
            419-599             JAXUCZ010000003.1  103036883-103037063
            600-687             JAXUCZ010000003.1  103327844-103327931
            688-825             JAXUCZ010000003.1  103600452-103600589
            826-919             JAXUCZ010000003.1  103939049-103939142
            920-972             JAXUCZ010000003.1  104110226-104110278
            973-5500            JAXUCZ010000003.1  104134695-104139222
FEATURES             Location/Qualifiers
     source          1..5500
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q31"
     gene            1..5500
                     /gene="Lrrc4c"
                     /gene_synonym="RGD1311013"
                     /note="leucine rich repeat containing 4C"
                     /db_xref="GeneID:311236"
                     /db_xref="RGD:1311013"
     exon            1..418
                     /gene="Lrrc4c"
                     /gene_synonym="RGD1311013"
                     /inference="alignment:Splign:2.1.0"
     exon            419..599
                     /gene="Lrrc4c"
                     /gene_synonym="RGD1311013"
                     /inference="alignment:Splign:2.1.0"
     exon            600..687
                     /gene="Lrrc4c"
                     /gene_synonym="RGD1311013"
                     /inference="alignment:Splign:2.1.0"
     exon            688..825
                     /gene="Lrrc4c"
                     /gene_synonym="RGD1311013"
                     /inference="alignment:Splign:2.1.0"
     exon            826..919
                     /gene="Lrrc4c"
                     /gene_synonym="RGD1311013"
                     /inference="alignment:Splign:2.1.0"
     exon            920..972
                     /gene="Lrrc4c"
                     /gene_synonym="RGD1311013"
                     /inference="alignment:Splign:2.1.0"
     exon            973..5500
                     /gene="Lrrc4c"
                     /gene_synonym="RGD1311013"
                     /inference="alignment:Splign:2.1.0"
     CDS             1015..2937
                     /gene="Lrrc4c"
                     /gene_synonym="RGD1311013"
                     /note="leucine-rich repeat-containing protein 4C"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 4C
                     precursor"
                     /protein_id="NP_001101223.1"
                     /db_xref="GeneID:311236"
                     /db_xref="RGD:1311013"
                     /translation="MLNKMTLHPQQIMIGPRFNRALFDPLLVVLLALQLLVVAGLVRA
                     QTCPSVCSCSNQFSKVICVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHL
                     EILQLSRNHIRTIEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPI
                     ESIPSYAFNRIPSLRRLDLGELKRLSYISEGAFEGLSNLRYLNLAMCNLREIPNLTPL
                     IKLDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAH
                     NNLTLLPHDLFTPLHHLERIHLHHNPWNCNCDILWLSWWIRDMAPSNTACCARCNTPP
                     NLKGRYIGELDQNYFTCYAPVIVEPPADLNVTEGMAAELKCRASTSLTSVSWITPNGT
                     VMTHGAYKVRIAVLSDGTLNFTNVTVQDTGMYTCMVSNSVGNTTASATLNVTAATTTP
                     FSYFSTVTVETMEPSQDEARTTDNNVGPTPVIDWETTNVTTSLTPQSTRSTEKTFTIP
                     VTDINSGIPGIDEVMKTTKIIIGCFVAITLMAAVMLVIFYKMRKQHHRQNHHAPTRTV
                     EIINVDDEITGDTPMESHLPMPAIEHEHLNHYNSYKSPFNHTTTVNTINSIHSSVHEP
                     LLIRMNSKDNVQETQI"
ORIGIN      
        1 gcctgctcct tgtaaaagag attgtgtgag tgtccgtact gtgtgtgtgg gcttgtgaga
       61 caaccaaagg ataggtatac cgtacaagag gagagctcaa cagcgtgata aaaatctcca
      121 ggcactgggg ctcacaagct gtagtccccc tcctctcacc gccccttctc tgccctactc
      181 ccccggctcc tttcgtcttt gatgagtttt tggctcactt tttggcggag tctcttggac
      241 atgttctgct gttgctggag gatcaaataa atggaacctt tgaaagttga ttatttttct
      301 cttatgtgac aaacatacac acagagagag cgcgaagagg aaaggaaatt agagtggtgt
      361 atgaccagct agaggattta aaattttcct tggtgaactt tgaggagcca ctgagaagaa
      421 accaaatgaa gtgtttactg tcattatctc tatttgatga agaggatact gaggctcaaa
      481 gagacttaat aactcgtcca agatcatcta atgctgagta atcaagagtg agtgccatga
      541 aggagcaaaa acccgcctgg accagcatag ttttgagagg ataaaccaca gagcagcaga
      601 aatgattcac ttgattgcaa gcctctatgt ttaccagaga gagtgaagct gaggaagttg
      661 gagcttctgt tgacactcta aactcatgaa ttactgaagg aacaaagaat aatgcatgta
      721 ttttgacaca atggagacat cctgacaccc cttcagaatc tcgataaatt aactggatta
      781 aagcttggcc aacaggaaaa ctggtacata gacaacttgc cacaggtgtg aagaaacttc
      841 accagtaggc atccagaaca tgcattttac ttctttgaat tccctcagga agagaagagc
      901 cagctagaca cactttaagg ttggcaaaca cgttgcctat ttactgcata gagaccccta
      961 atggagaaca agactgttta aactccagaa ggaccaacac cagataaatt atgaatgttg
     1021 aacaagatga ccttacatcc acagcagata atgataggtc ctaggtttaa cagggcccta
     1081 tttgaccccc tgcttgtggt gctgttggct cttcaacttc ttgtggtggc tggtctggtt
     1141 cgggctcaaa cctgcccttc agtgtgctct tgtagcaacc agttcagcaa ggtgatttgt
     1201 gttcggaaaa accttcgtga ggttcctgat ggcatctcca ccaacacaag gctgctgaac
     1261 ctccatgaga accaaatcca gatcattaaa gtgaacagct tcaagcattt gaggcacttg
     1321 gaaatcctcc agttgagcag gaaccatatt cgaaccattg aaatcggggc cttcaatggt
     1381 ctggcgaacc tcaacactct ggaactcttt gacaatcgtc ttaccaccat cccaaatgga
     1441 gcttttgtat atttgtctaa actgaaggag ctgtggttgc ggaacaaccc tattgaaagc
     1501 atcccttcct atgcttttaa cagaatccct tctttgcgcc gcctagactt aggggaattg
     1561 aaaaggcttt catacatctc agaaggtgcc tttgaaggtc tgtccaactt gaggtatttg
     1621 aaccttgcca tgtgcaacct ccgggaaatc cctaacctca cgccgctcat caaactagat
     1681 gagctagatc tttctgggaa ccatttgtct gcaatcaggc ctggctcttt tcaggggttg
     1741 atgcaccttc aaaaactgtg gatgatacag tctcagattc aagtgattga acggaatgcc
     1801 tttgataacc ttcagtcact agtggagata aacttggcac acaacaatct aacattactg
     1861 cctcatgacc tcttcacacc cttgcatcat ctagagagga tacaccttca ccacaaccca
     1921 tggaattgta actgtgacat cctgtggctc agctggtgga taagagacat ggccccctcc
     1981 aacacggctt gttgtgccag gtgtaacact ccccccaacc tgaaagggag gtacatcgga
     2041 gagctggacc agaattactt tacatgctat gctccagtaa ttgtggagcc ccctgcagac
     2101 ctcaatgtca ctgaaggcat ggccgctgag ctgaaatgtc gggcgtctac gtccctgact
     2161 tccgtatctt ggattactcc aaatggaact gtcatgaccc acggggcata caaagtgcgg
     2221 atagctgtgc tcagcgacgg tactttaaat ttcacaaatg taactgtgca agacacaggc
     2281 atgtacacat gtatggtgag taattctgtt ggcaacacca ctgcttctgc caccttgaat
     2341 gttactgcgg caaccactac tccattctcg tacttttcaa ctgtaacagt agagactatg
     2401 gaaccttctc aggatgaggc acggaccaca gataacaatg tgggccccac tccagtgatc
     2461 gattgggaga ccaccaatgt aaccacatct cttacgccac agagcacaag gtcgacagag
     2521 aaaacattca ccatcccagt aactgacatt aacagcggaa tcccaggaat tgatgaagta
     2581 atgaaaacaa caaaaatcat tattgggtgt tttgtggcca tcactctcat ggctgccgtg
     2641 atgctggtca ttttctataa gatgaggaaa cagcaccatc ggcaaaatca ccatgctcca
     2701 acgaggactg ttgaaatcat taacgtggat gatgagatca ctggggacac gcccatggaa
     2761 agccacctgc ccatgcctgc gattgagcat gagcacctaa accattataa ctcttacaaa
     2821 tctcccttca accacacaac aacagtaaac acaataaatt caatacacag ttcagtgcat
     2881 gaaccgttat tgatccgaat gaactctaaa gacaatgtac aagagactca gatataaaac
     2941 atttacagtt acagaaaaca aacaatcaaa aaagacagtt tattaaaaaa tgacacaaat
     3001 gactgggcta aatctactgt ttcaaaaaaa gtgtctttac aaaaaaaaac aaaaagaaaa
     3061 gaaatttatt tattaaaaat tctattgtga tctaaagcag acaaaattat gtgtattcct
     3121 cagaacctgt ttttgctgca cttactattt tcccacacct cctccctccc ctccccgatt
     3181 gccatatttt tcatagatct caactcccca aagaactggt ctaggaaatt ttgtaagaat
     3241 tctgttacac tttgagattt ttatggtgaa ttctagtggt gagatccagt ctattttgtc
     3301 tctttctctc tatatttttt tcattatttt ctttttcctt catgccctta tgaagtagtt
     3361 caatggggaa tgcaatatta gaaatagatt tttaagaaag aatgaggaaa atgcaagatc
     3421 ttatattttt catgtaataa cctgttctgt atttatgagg aggacattct gtggagaaag
     3481 aaaaagaagt aagcaaacag cagattaatt tacatatgag catctataaa acccatgact
     3541 tttaaaaaga aaaagaaaaa aaaacctcta gaatcagaat ttgtagttca aaagcttaaa
     3601 ataagattat aaataaaata ttgttggttt ttctgtacct ggacatagct catttgtaat
     3661 ctggctcaaa tgtgagaaac ctggaggtaa ttagattcct tgttttctaa gaaagataac
     3721 aaacactaca gtaacctcta atcacagcat tatttcctac atgtctctgc tgttttattt
     3781 gcttattaca catcaacatt caaagatact aagatattct tgccttacct actaggaggg
     3841 acccttgtaa ccttttggat ggaaagttaa caatttgcaa actaaatgta attcagggaa
     3901 ggagaaaata ccagtatgat atattttctt tcttctaaag aaaactctgc agaccagctg
     3961 aaatagtacc acaaaagacg agtcattctt aattgctcac agttgaaaag gaatttggag
     4021 ttctgagtgt tagcaaattt agttcaattc attgaaaatt atcacagagc agaaaggagc
     4081 taaatggtca cttggctgat gtgagtccac aaatagcaag gcctagttcc tgcccttgca
     4141 tcgtttccaa ggatttttct cactgtatta ctaagcacta gcactaatgt ttataggtaa
     4201 atgatagtgt cctaggcact ctaaattgca aaatattaaa atgttataga aacttactga
     4261 attcatgatt tctgccatgc ttcaggtgga gagaactttc ttcttcagaa aacagactcc
     4321 caggagttta agaagcaaaa acaatggagt attgtgaaat aatgggcaca tatgaacaga
     4381 aaacaagcct gatgaaatac atgatgactt accaggactt tctttaaagg agctgtggca
     4441 atcttagcta agaggacaga aaattgcttc caaaaagaaa aagaatccac tggttgtgaa
     4501 tgcttgcatt ctctcaatat tttcacatac tttgtgtatg aactttatct ttctatctgt
     4561 ggtacaatat atagacagag agacagacag agagacagag agacagacac acacaaacac
     4621 acacaactcc cccccacaca cttctcactg accttgaaat ctgtccttgc catcaaaccc
     4681 aggagataac gaatgactaa attgagggaa atgcatctcc cagtggatga gcagcttgaa
     4741 cacttgcatg taattctaca gtctagacct cacaccaggt ttcgtgatca ccgggtttga
     4801 aaaaccagtc atttctaaca gtgtagatta aaaaaaatag gaggaagagt taagaaatgg
     4861 atgcaaagac acaaaagtcc tgtttcgttt ttttggccac acaccctttg gctattttct
     4921 cctgtatccc ttcttccctt tatcacaaac ctaatttaca ttttctgtta ctgttcagta
     4981 gacataggca aagggcaagc atatatggac tgtcattcac atatatagca tggtgtgtgg
     5041 ttgcatagca ttctaacaga aacgtacact catacacaaa catatacatt ttaaatatta
     5101 actagatctg ggacaaagaa gggggatatt aatgagtgaa gaaatgggtg gtgccttctt
     5161 ttcttaattc tgttcctagt ttttgtttac aaacttctgc ctcttgactc tctcatgtta
     5221 agcttatgat tattataagg gtacccaaaa atgttcaaac catatactat ttgtcatggc
     5281 taaacagtta gacaaattgt cctaaatgca atggaatata aaataaccaa ataaaacaaa
     5341 caatagacga acagacaaac caaaatcagt gagtagaaaa tcaaaactat gagatacctg
     5401 cgaccagaat actacaatag attgaaacaa cacatttcag aaataaaata cacgtatgga
     5461 aggtttaaat taattaaatt gagttatata tcaaattaaa
//
