LOCUS       NM_001271081            2744 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus leucine rich repeat containing 4B (Lrrc4b), mRNA.
ACCESSION   NM_001271081 XM_218615
VERSION     NM_001271081.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2744)
  AUTHORS   Wentzel,C., Sommer,J.E., Nair,R., Stiefvater,A., Sibarita,J.B. and
            Scheiffele,P.
  TITLE     mSYD1A, a mammalian synapse-defective-1 protein, regulates
            synaptogenic signaling and vesicle docking
  JOURNAL   Neuron 78 (6), 1012-1023 (2013)
   PUBMED   23791195
REFERENCE   2  (bases 1 to 2744)
  AUTHORS   Yoshida,T., Yasumura,M., Uemura,T., Lee,S.J., Ra,M., Taguchi,R.,
            Iwakura,Y. and Mishina,M.
  TITLE     IL-1 receptor accessory protein-like 1 associated with mental
            retardation and autism mediates synapse formation by trans-synaptic
            interaction with protein tyrosine phosphatase delta
  JOURNAL   J Neurosci 31 (38), 13485-13499 (2011)
   PUBMED   21940441
REFERENCE   3  (bases 1 to 2744)
  AUTHORS   Woo,J., Kwon,S.K., Choi,S., Kim,S., Lee,J.R., Dunah,A.W., Sheng,M.
            and Kim,E.
  TITLE     Trans-synaptic adhesion between NGL-3 and LAR regulates the
            formation of excitatory synapses
  JOURNAL   Nat Neurosci 12 (4), 428-437 (2009)
   PUBMED   19252495
REFERENCE   4  (bases 1 to 2744)
  AUTHORS   Kim,S., Burette,A., Chung,H.S., Kwon,S.K., Woo,J., Lee,H.W.,
            Kim,K., Kim,H., Weinberg,R.J. and Kim,E.
  TITLE     NGL family PSD-95-interacting adhesion molecules regulate
            excitatory synapse formation
  JOURNAL   Nat Neurosci 9 (10), 1294-1301 (2006)
   PUBMED   16980967
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Aug 30, 2012 this sequence version replaced XM_218615.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            CDS exon combination :: CB608563.1, CB740574.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA5760393, SAMEA5760433 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-45                JAXUCZ010000001.1  104072128-104072172
            46-383              JAXUCZ010000001.1  104074388-104074725
            384-2744            JAXUCZ010000001.1  104090471-104092831
FEATURES             Location/Qualifiers
     source          1..2744
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..2744
                     /gene="Lrrc4b"
                     /gene_synonym="Lrig4; NGL-3"
                     /note="leucine rich repeat containing 4B"
                     /db_xref="GeneID:308571"
                     /db_xref="RGD:1307121"
     exon            1..45
                     /gene="Lrrc4b"
                     /gene_synonym="Lrig4; NGL-3"
                     /inference="alignment:Splign:2.1.0"
     exon            46..383
                     /gene="Lrrc4b"
                     /gene_synonym="Lrig4; NGL-3"
                     /inference="alignment:Splign:2.1.0"
     CDS             81..2210
                     /gene="Lrrc4b"
                     /gene_synonym="Lrig4; NGL-3"
                     /note="netrin-G3 ligand; protein NGL-3; leucine-rich
                     repeat-containing protein 4B"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 4B
                     precursor"
                     /protein_id="NP_001258010.1"
                     /db_xref="GeneID:308571"
                     /db_xref="RGD:1307121"
                     /translation="MAQAHIQGSPCPLLPPGRMSWPQGALLLLWLFSPPLRAGGGGVA
                     VTSAAGGGSPPATSCPAACSCSNQASRVICTRRELAEVPASIPVNTRYLNLQENSIQV
                     IRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLS
                     KLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNLGM
                     CNLKDIPNLTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFD
                     DLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCNCDVLWLSWWLKETVPS
                     NTTCCARCHAPAGLKGRYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTS
                     MTSVNWLTPNGTLMTHGSYRVRISVLHDGTLNFTNVTVQDTGQYTCMVTNSAGNTTAS
                     ATLNVSAVDPVAAGGPGGGGPGGGGGAGGAGGYTYFTTVTVETLETQPGEEAQQPRGT
                     EKEPPGPTTDGAWGGGRPDAAAPASASTTAPAPRSSRPTEKAFTVPITDVTENALKDL
                     DDVMKTTKIIIGCFVAITFMAAVMLVAFYKLRKQHQLHKHHGPTRTVEIINVEDELPA
                     ASAVSVAAAAAVAGGAGVGGDSHLALPALERDHLNHHHYVAAAFKAHYGGNPGGGCGA
                     KGPGLNSIHEPLLFKSGSKENVQETQI"
     exon            384..2744
                     /gene="Lrrc4b"
                     /gene_synonym="Lrig4; NGL-3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcctggggc acagagagaa ggccatcgga agccgagccg ccaggccccc cagcgtaccc
       61 tcggagtatg aacattgagg atggcgcagg cccacatcca aggctccccg tgccccttgc
      121 tgccgcctgg taggatgtcc tggccccaag gggctctcct gctcctgtgg ctcttctccc
      181 cacccctgag ggccggtggg ggcggtgtgg ccgtgacttc agccgccgga ggaggctccc
      241 cgccagccac ctcctgccca gcagcctgct cctgcagcaa ccaggccagc cgggtgatct
      301 gcacgcggag ggagctggcc gaggtgccag ccagtatccc cgtcaatacc cgctacctga
      361 acttgcaaga gaacagcatt caggtgatcc gcactgacac attcaagcac ctccggcacc
      421 tggagatcct gcagctgagc aagaatctgg tgcgcaagat cgaagtgggg gcgttcaatg
      481 ggcttcccag tctcaacaca ctggaactct tcgacaaccg gctgaccaca gtgcccacac
      541 aggcctttga gtacttgtcc aagctccggg agctgtggct gcgcaacaac cccatcgaaa
      601 gcatcccatc ctatgccttc aaccgtgtgc cctcattgcg ccgcctggac ctgggcgagc
      661 tgaagcgtct ggagtacata tcggaggcgg ccttcgaggg gctggtgaac ctgcgctacc
      721 tcaacctggg catgtgcaac ctaaaggaca tccccaacct cacagcactt gtgcgcctgg
      781 aagagctgga gctgtcgggg aaccggctgg acctaattcg ccccggctcc ttccagggcc
      841 tcaccagcct gcgcaagctg tggctgatgc atgcccaagt ggccaccatc gagcgaaacg
      901 ccttcgacga cctcaagtcg ctggaggagc tgaacctgtc ccacaacaac ctgatgtcgc
      961 tgccgcacga ccttttcaca ccccttcacc gcctggagcg tgtccacctg aaccacaacc
     1021 cctggcactg caactgtgat gtgctctggc tcagctggtg gctgaaggag acagtgccca
     1081 gcaataccac atgctgcgca cgctgccacg cgcccgccgg cctcaagggc cgctacatcg
     1141 gtgagctgga ccagtcgcac ttcacctgct atgccccagt catcgtggag ccacccacag
     1201 acctcaatgt caccgagggc atggcggccg agctcaagtg ccgcacaggt acatccatga
     1261 cctcggtcaa ctggctgaca cctaacggca cgctcatgac acacggttcc tatcgtgtgc
     1321 gcatttcggt actgcacgat ggcacactca atttcactaa tgtcaccgtg caggacacgg
     1381 gccagtacac gtgcatggtg acaaactctg ctggcaacac cactgcctcg gccacgctta
     1441 acgtgtcggc cgtggaccct gtggctgccg gagggcccgg tggcgggggc ccagggggtg
     1501 ggggcggtgc agggggtgcg ggcggctaca cctacttcac cacggtgact gtggagacgc
     1561 tggagacaca gccgggggag gaggcccagc agccccgagg tactgagaag gagcccccgg
     1621 ggcccacgac tgatggcgcg tggggtggcg gccggcctga cgctgcagcc ccggcctcag
     1681 cgtccaccac ggcaccagcc ccgcgctcct cgcggcccac agagaaggct ttcacggtgc
     1741 ccatcacgga cgtgacggag aacgcactta aggacctaga cgatgtcatg aagaccacca
     1801 aaatcatcat cggctgcttc gtggccatca cctttatggc cgccgtgatg ctggtggcct
     1861 tctacaagct gcgcaagcag caccagctgc acaagcacca tgggcccacg cgcactgtgg
     1921 agatcatcaa cgtggaggac gagctgcccg ccgcctccgc tgtgtcggtg gctgcggccg
     1981 ctgcggtggc tggaggcgcg ggcgtgggtg gggacagcca cctggctctt ccggcgctgg
     2041 agcgagacca cctcaaccac caccactacg tggcggctgc cttcaaggcg cactacggcg
     2101 gcaatccagg aggcgggtgc ggggccaagg gccccggcct caactccatc cacgaacctc
     2161 tgctcttcaa gagcggctcc aaggagaacg tgcaagagac acaaatctaa acttaggcgc
     2221 gcggggacgc ggggacgcag gacgcctgcc cgagatgctc ctgcttaccc agcagccctg
     2281 gcggcgcctg cctgtcctgc aatgggaaag gacctggaga tcaggagagg tggccccacc
     2341 ctccgccttg ccgtgtcctc tgcccacctg ccctgcccgc caccttcctg ggttgaggag
     2401 cttcttcgag gggtaccctt tcccctcatc ccaacaaccc ttcttttatg gctctttctt
     2461 ttttctttat ttctttgttt tttccccctt ttgcagtttg acgcctgtcc gtccctccta
     2521 ctccaccacc ctcaaaacac aagagacaga caacttcacc agagcccagg gggcaactcc
     2581 gacagtgtcc ccaacagcga gctccactcg cggccctggc cggccctact caccccacag
     2641 actcttttga tactgaaggg aggtttgcgt caatcactac ctgctctgta attactttaa
     2701 aaaaaaaaaa aaaaacacgg aaaaagtaaa aaaaaaaaaa aaaa
//
