LOCUS       NM_001004201            1325 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Rattus norvegicus leucine rich repeat containing 46 (Lrrc46), mRNA.
ACCESSION   NM_001004201 XM_213444
VERSION     NM_001004201.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1325)
  AUTHORS   Hasson,S.A., Kane,L.A., Yamano,K., Huang,C.H., Sliter,D.A.,
            Buehler,E., Wang,C., Heman-Ackah,S.M., Hessa,T., Guha,R.,
            Martin,S.E. and Youle,R.J.
  TITLE     High-content genome-wide RNAi screens identify regulators of parkin
            upstream of mitophagy
  JOURNAL   Nature 504 (7479), 291-295 (2013)
   PUBMED   24270810
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079258.1.
            
            On Sep 10, 2004 this sequence version replaced XM_213444.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079258.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1325
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q31"
     gene            1..1325
                     /gene="Lrrc46"
                     /note="leucine rich repeat containing 46"
                     /db_xref="GeneID:287653"
                     /db_xref="RGD:1303311"
     exon            1..242
                     /gene="Lrrc46"
                     /inference="alignment:Splign:2.1.0"
     CDS             221..1192
                     /gene="Lrrc46"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 46"
                     /protein_id="NP_001004201.1"
                     /db_xref="GeneID:287653"
                     /db_xref="RGD:1303311"
                     /translation="MPGDKQEAKNATQKTEEGVHITEALITKRNLTFPEDEDLSEKMF
                     HTLDDLETVRLDGEGITCIGNLERLRNIHSLYLQSNKIQRIENLACITSLRFLSLAGN
                     QIRHVENLLDLQYLQFLDLSENLIETLKLDELPQSLLILNLCGNPCTNQDGYRKMVIG
                     ALPLLLDLDKQPILERWTSDEEDKSSDEEEEFPELNGPFCAERGFFKDLEQELHQHQE
                     RRQQAALTEHLSRMETQPVLTDLPLLPAVPMAGDCSPAVTEEPGKEAAPKATSSTQMA
                     SSSKKQVPRNQKGSVQARKGALAATASKTSLAAAPSMTKSTNKRGTK"
     exon            243..348
                     /gene="Lrrc46"
                     /inference="alignment:Splign:2.1.0"
     exon            349..457
                     /gene="Lrrc46"
                     /inference="alignment:Splign:2.1.0"
     exon            458..504
                     /gene="Lrrc46"
                     /inference="alignment:Splign:2.1.0"
     exon            505..614
                     /gene="Lrrc46"
                     /inference="alignment:Splign:2.1.0"
     exon            615..684
                     /gene="Lrrc46"
                     /inference="alignment:Splign:2.1.0"
     exon            685..830
                     /gene="Lrrc46"
                     /inference="alignment:Splign:2.1.0"
     exon            831..1259
                     /gene="Lrrc46"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcctttcag tttaaggcca gtaaagccac gccacacacc tgtaactcca gatccttcgc
       61 tcctatttac tcctatcttc caccgcaccc ccaacaaccc tcagaacccc ctgtccttat
      121 ctccttagtc ttccctctaa cctgggttca accctcccaa ccgtctaacc ttcacagctt
      181 ttcttcgtcg atctgcctca agcagccgct gttttagatc atgccaggag acaagcagga
      241 agctaagaat gctacccaga aaaccgagga aggtgtccac attactgaag cccttatcac
      301 caagcggaac ttgaccttcc ctgaagatga agacctgtca gaaaagatgt ttcacactct
      361 cgacgatctg gagactgtcc gcctggatgg ggaagggatt acctgtatcg ggaatttaga
      421 gcgtctccgg aatattcaca gcctttacct gcaatcgaat aagatccagc gcattgagaa
      481 cttggcgtgc atcacctccc tgcgcttcct gtctctggca ggaaaccaaa tcaggcacgt
      541 ggaaaacctc cttgacctgc agtacctcca gtttctggac ctttctgaga acctgataga
      601 aacactgaag ctagatgagc tcccccagag ccttctcatt ctcaacctgt gtggaaatcc
      661 ctgcaccaac caggatggct acaggaagat ggtgatagga gccctgccgt tgctcctgga
      721 cctggacaag cagcctatac tggagcggtg gacctcggat gaggaggaca aatcctcgga
      781 cgaggaggag gagtttccag agctcaatgg ccccttctgc gcagagcgag gattcttcaa
      841 ggacttggag caggaactgc atcagcatca ggaacgcagg cagcaggctg ccctgacgga
      901 gcacttgtca aggatggaga cacagcctgt cctcacagac ctgcccctgc tgcctgctgt
      961 gcccatggct ggggactgca gccctgctgt cactgaagag cccgggaagg aggcagcccc
     1021 taaagctacc tcttcaaccc agatggcctc ttcttccaag aaacaggttc ccaggaacca
     1081 gaaaggctct gtccaggcaa ggaagggggc tctagcagcc acagcatcca agacctctct
     1141 ggctgcagct cccagcatga caaaaagtac aaacaaaaga ggcacaaagt aacgcacagc
     1201 ctctactcac aggcctcctt cccaggtcct gccccaataa agcgtctctg ggcttggaaa
     1261 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1321 aaaaa
//
