LOCUS       NM_001009710            2954 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus leucine rich repeat containing 41 (Lrrc41), mRNA.
ACCESSION   NM_001009710 XM_342884
VERSION     NM_001009710.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2954)
  AUTHORS   Schenkova,K., Lutz,J., Kopp,M., Ramos,S. and Rivero,F.
  TITLE     MUF1/leucine-rich repeat containing 41 (LRRC41), a substrate of
            RhoBTB-dependent cullin 3 ubiquitin ligase complexes, is a
            predominantly nuclear dimeric protein
  JOURNAL   J Mol Biol 422 (5), 659-673 (2012)
   PUBMED   22709582
REFERENCE   2  (bases 1 to 2954)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 2954)
  AUTHORS   Kamura,T., Burian,D., Yan,Q., Schmidt,S.L., Lane,W.S., Querido,E.,
            Branton,P.E., Shilatifard,A., Conaway,R.C. and Conaway,J.W.
  TITLE     Muf1, a novel Elongin BC-interacting leucine-rich repeat protein
            that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin
            ligase
  JOURNAL   J Biol Chem 276 (32), 29748-29753 (2001)
   PUBMED   11384984
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001009710.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087037.1, SRR26643286.17674.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-237               JAXUCZ010000005.1  134791256-134791492
            238-324             JAXUCZ010000005.1  134795427-134795513
            325-395             JAXUCZ010000005.1  134796680-134796750
            396-1521            JAXUCZ010000005.1  134803934-134805059
            1522-1782           JAXUCZ010000005.1  134808224-134808484
            1783-1947           JAXUCZ010000005.1  134810033-134810197
            1948-2046           JAXUCZ010000005.1  134810288-134810386
            2047-2169           JAXUCZ010000005.1  134810919-134811041
            2170-2245           JAXUCZ010000005.1  134811291-134811366
            2246-2954           JAXUCZ010000005.1  134811469-134812177
FEATURES             Location/Qualifiers
     source          1..2954
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q35"
     gene            1..2954
                     /gene="Lrrc41"
                     /gene_synonym="RGD1311221"
                     /note="leucine rich repeat containing 41"
                     /db_xref="GeneID:362566"
                     /db_xref="RGD:1311221"
     exon            1..237
                     /gene="Lrrc41"
                     /gene_synonym="RGD1311221"
                     /inference="alignment:Splign:2.1.0"
     CDS             39..2465
                     /gene="Lrrc41"
                     /gene_synonym="RGD1311221"
                     /note="MUF1 protein"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 41"
                     /protein_id="NP_001009710.1"
                     /db_xref="GeneID:362566"
                     /db_xref="RGD:1311221"
                     /translation="MAAPEAWRARSCWFCEVAAATTMEATSREAAPAKSSASGPSAPP
                     ALFELCGRAVSAHMGVLESGVWALPGPILQSILPLLNIYYLERIEETALKKGLSTQAI
                     WRRLWDELMKTRPSSLESVTCWRAKFMEAFFSHVLRGTIDVSSDKRLCDQRFSPLLHS
                     SRHVRQLTICNMLQGATELVAEPNRRVLETLASSLHTLKFRHLLFSDVAAQQSLRQLL
                     HQLIHHGAVSQVSLYSWPVPESALFILILTMSAGFWQPGPGSLPCRLCGEASRGRAPS
                     RDEGSLLLGSRRPRRDAAERCAAALMATRRKSEVKQVPRALPTSRVTRRSTQESLTIG
                     GTDSKRELYPPATSYEASGTKQPSSAPTAASSSTSSKRAPASSVSQPKPLKRFKRATG
                     KKGPRTRQGSGAESEDLYDFVFIVAGEKEDGEEMEIGEVACGALDGSDPSCLGLPALE
                     ASQRFRSISTLELFTVPLSTEAALTLCHLLSSWVSLESLTLSYNGLGSNIFRLLDSLR
                     VLSGQAGCRLRALHLSDLFSPLPILELTRAIVRALPLLRVLSIRVDHPSQRDNPAVPE
                     NAGPPGHIIGDEEIPENCLEQLEMGFPRGAQPAPLLCSVLKASGSLQQLSLDSATFAS
                     PQDFGLVLQTLKEYNLSLKRLSFHDMNLADCQSEVLFLLKNLTLQEITFSFCRLFEKR
                     PAQFLPEMVAAMKGNSTLKGLRLPGNRLGNAGLLALADVFSEDSSSSLCQLDISSNCI
                     KPDGLLEFAKRLERWGRGAFGHLRLFQNWLDQDAVTAREAIRRLRATCHVVSDSWDST
                     QAFADYVSTM"
     exon            238..324
                     /gene="Lrrc41"
                     /gene_synonym="RGD1311221"
                     /inference="alignment:Splign:2.1.0"
     exon            325..395
                     /gene="Lrrc41"
                     /gene_synonym="RGD1311221"
                     /inference="alignment:Splign:2.1.0"
     exon            396..1521
                     /gene="Lrrc41"
                     /gene_synonym="RGD1311221"
                     /inference="alignment:Splign:2.1.0"
     exon            1522..1782
                     /gene="Lrrc41"
                     /gene_synonym="RGD1311221"
                     /inference="alignment:Splign:2.1.0"
     exon            1783..1947
                     /gene="Lrrc41"
                     /gene_synonym="RGD1311221"
                     /inference="alignment:Splign:2.1.0"
     exon            1948..2046
                     /gene="Lrrc41"
                     /gene_synonym="RGD1311221"
                     /inference="alignment:Splign:2.1.0"
     exon            2047..2169
                     /gene="Lrrc41"
                     /gene_synonym="RGD1311221"
                     /inference="alignment:Splign:2.1.0"
     exon            2170..2245
                     /gene="Lrrc41"
                     /gene_synonym="RGD1311221"
                     /inference="alignment:Splign:2.1.0"
     exon            2246..2954
                     /gene="Lrrc41"
                     /gene_synonym="RGD1311221"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgcgggtgt cattctcggg ctcgcgcacc tccccaagat ggcggcgccc gaggcctggc
       61 gcgcccggag ttgctggttc tgtgaggtag cggcagcaac gaccatggag gccacgtccc
      121 gggaggcggc gccagcgaag agctcggcct cgggccccag cgctcccccc gccctgttcg
      181 agttgtgcgg gcgggcagtg agcgcccata tgggggttct ggagagcggg gtgtgggccc
      241 tcccaggccc aatacttcaa agcatcttac ctctgctcaa tatatattac ttggagagga
      301 ttgaggaaac tgctctcaaa aaaggtctct ctactcaagc catctggcgc cgactctggg
      361 atgagctgat gaagacaagg ccttccagtt tggagagtgt gacttgctgg cgagccaagt
      421 ttatggaggc ctttttttcc catgttctcc gtggaaccat tgacgtgtct tctgataagc
      481 gtctttgtga tcaacgcttc tcacctctcc tgcacagctc ccgccatgtc cgacagctaa
      541 ccatctgcaa tatgctgcag ggagcgaccg agctagtggc agagcccaac cgcagggttc
      601 tggagaccct ggccagctct ctgcacaccc tcaagttccg ccacctgctg ttctcggatg
      661 tggccgctca gcagtcactc cgacagctct tgcatcagct catccaccat ggggctgtta
      721 gccaagtctc gctgtactcc tggcctgtgc ccgagtcagc ccttttcatc cttatcctta
      781 ccatgagtgc tggcttttgg cagccaggcc ctggtagctt gccttgccgc ctctgtggtg
      841 aagcctcccg aggccgggcc ccatctagag atgaagggtc cttgttgcta ggctctcgca
      901 ggcctcggcg tgatgcagca gaacgatgtg ctgcagcact gatggccacc cggcggaaga
      961 gtgaagtcaa gcaggtgccc agggctctcc ctaccagtcg tgtaacacgc cgcagcacac
     1021 aagaaagcct gacaataggt ggaacagact ctaagaggga gttgtacccc ccagccacct
     1081 cttatgaggc ttctggcact aagcagccat cctctgctcc aactgcagcc tcctcttcca
     1141 catcatccaa acgagctcca gctagctcag tctcacagcc taagccctta aagcgtttca
     1201 aacgagctac agggaagaaa ggtccccgca cccgtcaggg gtctggtgca gagtctgaag
     1261 acctgtatga ctttgttttt attgtggctg gtgagaaaga ggatggtgaa gagatggaga
     1321 ttggggaagt agcttgcgga gctctggatg gatcagatcc cagctgtttg gggctcccag
     1381 cactagaggc atcccagcga ttccgcagca tttccaccct ggagctgttc acagttcctc
     1441 tttccacaga ggcagctctg acactgtgcc atctgctgag ctcctgggta tcactggaga
     1501 gccttacact ttcctacaat ggtctgggct ccaatatctt ccgcctcctg gacagcctac
     1561 gggtcctgtc aggccaggct ggatgtcgtc tccgtgccct gcatctcagt gaccttttct
     1621 caccactgcc catcctggaa ttgacccgtg ccattgtgcg agccttgccc ctgttgcggg
     1681 tcctgtctat tcgtgttgat cacccaagcc agagggacaa ccctgctgta ccagagaatg
     1741 ctgggccccc tggacacata attggagatg aagaaatacc agaaaactgc ctagagcagt
     1801 tggaaatggg atttccacga ggagcccagc cagccccact gctctgctct gttctgaagg
     1861 cctcaggttc tctacagcag ctgtcactcg acagtgccac cttcgcctct cctcaagatt
     1921 ttgggcttgt tttgcaaaca ctcaaagaat acaacctgtc cctgaagagg ctgagtttcc
     1981 atgatatgaa tcttgcagac tgtcagagtg aggtgctctt tttgttaaag aatctgaccc
     2041 ttcaagagat taccttctcc ttctgtcgtc tgtttgagaa gcgcccagcc caatttcttc
     2101 ctgagatggt tgctgctatg aagggcaact ctacactgaa gggccttcga ctaccaggga
     2161 accgcctagg gaatgctggc ctattagccc tagcagatgt tttctcagag gattcttcct
     2221 cttctctctg tcagctggac atcagctcca actgcatcaa gccagatggg cttttggagt
     2281 ttgccaaacg actggagcgc tggggccgtg gagcctttgg tcatctacgc ctcttccaga
     2341 actggctgga ccaggatgca gtaacagcga gagaagcaat ccggcgactc cgggctacct
     2401 gccacgtggt tagcgactca tgggactcaa cccaggcctt tgcagattat gtcagcacca
     2461 tgtgatgggg cccatacctc acaggcccat cctcagtacc gtcagcttgc agggactgag
     2521 ccatgggctg cccagaaccc ctaaccactg attctgtcat cctcctcctg ccactttgtc
     2581 tatttctgtt ttgttttcat cttccctggc actgaggtcc tggaggcctc aatgaggccc
     2641 agcaaaggca ttcccacagc tgagttcaga ggctttgggc cacttactcg gtactctggg
     2701 aaccccaggc caggttatgg gtctctgtct tcactgagga aagcccctac ccctgctctg
     2761 gggtttcctg cttcactcct caagcaggta cccaggctta gagcagtata ggaatgccta
     2821 ccatcaggcc tctccctcct gggcttccca gtctggtccc gggcctcaat ccctttcatg
     2881 cctttattcc tttctttttt ttttttttaa accaaaaaag tttttcttat aaaataaatt
     2941 ttgggcaaac atca
//
