LOCUS       NM_001109637            2875 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Rattus norvegicus leucine rich repeat containing 39 (Lrrc39), mRNA.
ACCESSION   NM_001109637 XM_001077333
VERSION     NM_001109637.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2875)
  AUTHORS   Will,R.D., Eden,M., Just,S., Hansen,A., Eder,A., Frank,D., Kuhn,C.,
            Seeger,T.S., Oehl,U., Wiemann,S., Korn,B., Koegl,M., Rottbauer,W.,
            Eschenhagen,T., Katus,H.A. and Frey,N.
  TITLE     Myomasp/LRRC39, a heart- and muscle-specific protein, is a novel
            component of the sarcomeric M-band and is involved in stretch
            sensing
  JOURNAL   Circ Res 107 (10), 1253-1264 (2010)
   PUBMED   20847312
  REMARK    GeneRIF: Reveal myomasp/LRRC39 as a previously unrecognized
            component of an M-band-associated signaling pathway that regulates
            cardiomyocyte gene expression in response to biomechanical stress.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473952.1.
            
            On Oct 4, 2007 this sequence version replaced XM_001077333.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ215425.1, BC158606.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760384, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2875
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q42"
     gene            1..2875
                     /gene="Lrrc39"
                     /note="leucine rich repeat containing 39"
                     /db_xref="GeneID:691307"
                     /db_xref="RGD:1585106"
     exon            1..153
                     /gene="Lrrc39"
                     /inference="alignment:Splign:2.1.0"
     exon            154..344
                     /gene="Lrrc39"
                     /inference="alignment:Splign:2.1.0"
     CDS             232..1236
                     /gene="Lrrc39"
                     /note="myomasp; myosin-interacting M-band-associated
                     stress-responsive protein"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 39"
                     /protein_id="NP_001103107.1"
                     /db_xref="GeneID:691307"
                     /db_xref="RGD:1585106"
                     /translation="MTESVVCTGAVSTVKEVWEERIKKHHEDVKREKEFQQKLVRIWE
                     DRVSLTKLKEKVTREDGRIILRIEKEEWKTLPSSLLKLNQLQEWQLHRTGLLKIPEFI
                     GRFQHLIVLDLSRNTISEIPRGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELA
                     VNRDISDLPTELSKLLKLTHLDLSMNQFTTIPLAVLDMPALEWLDMGSNSLQQLPDTL
                     DRMQSLHTLWLQRNEITCLPETIRNMKNLGTLVLSNNKLQDIPGCMEEMTSLRFVNFR
                     DNPLRLEVTLPPSDDVDGEEEQELFGLQFMHAYIQESRRTEDQVNCLTHTPSSTRSDG
                     "
     exon            345..450
                     /gene="Lrrc39"
                     /inference="alignment:Splign:2.1.0"
     exon            451..607
                     /gene="Lrrc39"
                     /inference="alignment:Splign:2.1.0"
     exon            608..744
                     /gene="Lrrc39"
                     /inference="alignment:Splign:2.1.0"
     exon            745..890
                     /gene="Lrrc39"
                     /inference="alignment:Splign:2.1.0"
     exon            891..1043
                     /gene="Lrrc39"
                     /inference="alignment:Splign:2.1.0"
     exon            1044..1180
                     /gene="Lrrc39"
                     /inference="alignment:Splign:2.1.0"
     exon            1181..2875
                     /gene="Lrrc39"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tagaacgagg ctgacattac ttttcacttg gttacagcct gacagagagt tatagtcatt
       61 tggatccaca ctgggggaaa aatcacctcg tgatctgatc cgagctgaga cttggggagc
      121 tctggctccg tgttggctgc agcatccccc atggtcttgt ctgaggtgtc ctgtgactcg
      181 actcttcaga actcaatgaa gtagatgact tgactacaat gtggaaacat catgacagaa
      241 agtgtggttt gtaccggggc cgtcagcact gtaaaggaag tctgggaaga aagaataaag
      301 aaacatcatg aagatgtgaa acgagagaag gaatttcagc aaaagctagt gcggatctgg
      361 gaagaccgag tgagtttaac taagctgaaa gagaaggtga ccagggaaga tggaagaatc
      421 attctaagga tagagaaaga ggaatggaag actctccctt cttccttact gaaactgaat
      481 cagctacagg agtggcaact tcataggacc ggattgttga aaattcctga attcattgga
      541 agattccagc atctcattgt tctagactta tctcggaaca caatttcaga gatcccccga
      601 ggcattggac tgctcactag acttcaggaa ctgattctta gctacaacaa aatcaagact
      661 gtccccaaag aactgagcaa ctgtgccagc ttggagaagc tagaactggc tgtaaacaga
      721 gatataagcg acctcccgac agagctcagc aaactgttaa aactcactca ccttgacctg
      781 agcatgaacc agttcaccac aatccctctt gctgtgctgg acatgcctgc cctcgagtgg
      841 ctggatatgg gaagcaacag ccttcaacag cttcctgata cactagacag aatgcaaagt
      901 ttacatacac tgtggctaca gaggaatgaa ataacatgcc tgccagagac aatcaggaat
      961 atgaaaaact tggggactct tgttctcagc aacaacaagc tacaagatat tccaggctgc
     1021 atggaagaaa tgacgagtct gaggttcgtc aactttcgag acaacccact aagactggaa
     1081 gtgacacttc ctcccagtga tgacgtagat ggagaggaag aacaggagtt atttgggctt
     1141 cagttcatgc acgcatacat acaagagtca cggagaacag aagaccaagt caactgtctg
     1201 actcatacgc ccagctctac acggtctgat ggataaagta atttaaagag tcccgctgaa
     1261 aaggaatact tcgacaactg ggtgaatatt tttgtgacta tcaaaatata atttaaaaat
     1321 aatttattta ttttttgctt gtggaagaca tcatgttcat gtttcctttc actgattgat
     1381 ttttttcctg cgatgacaga tgagccggta cagcagttaa taatacattt tccagagaca
     1441 ccaatgggtc cgtatagtac tgtaaggcag gactgaagcc tttctgctgt aaatactgga
     1501 gtcggccttg gtcaatcagc aatttgcaaa gatgtcctat tttcttcttt tcttcaacag
     1561 taagagtcct acattgaata aacacacaaa acttaaaagt tggtaaacgt tcctaaggag
     1621 ttcggcccct ccatctactc caaggctgct aaggagccgg cagcacaata ggtaccatgg
     1681 ctgatgcttc tgagacttcc ctttctgatc acaattaaaa catgcttcag tttactccaa
     1741 aattaggata gaagctacat ttttctaaat ttttgttaac agtcacctaa gaaaaaaaga
     1801 atcctttcca tcctcagctt cactttctat attgatctca gccaaaagac taagaaacaa
     1861 ccattccgtt tcatttctct ggtttccctt gcccaaggtc agtagtttga aaatattaaa
     1921 cggaaaattc tgaaaacaag ccattggtaa tgccgtgctg cctagcatgg tgaatcacgg
     1981 gcactcaact ccttcccacc cggggaacgg acctgtgcct cgcacctgag cgtccctagc
     2041 gaatccgcat tgcatgttac cccctcgcta gacgctgtgc agccatctcg gttacgcgac
     2101 tgacagagtg ggtagctgcg tgtagggctc tgtttcacct agggttctag gcatctgtgg
     2161 gaggtcctac agtattaccc acaggaggcc tagattacgg tgataaacta tctccccgca
     2221 gtgaggtgtt tacggacgtc atcacttacc caggcaaact gtcagtgctg ccatccgtga
     2281 gtctgtctcc tacatcatcg tgctcttcct cctcatcctt ctgagcatct tttctctctg
     2341 cagtaacatc tgaggcttcc aaagacgtcc tcatcccaca cgttgcccaa ctactcattc
     2401 tctggaaata gtagaactcc actgcgccaa gcccaagagc cttgaaatac tctttgccca
     2461 cataatgtct ccagtcacac ctgtggtgac aacagagcgc aatgacaatg ccagccacag
     2521 gggtccgtgt ctctgggaca tctttttcac ttccttcctt ggccaaagtg ttactttctt
     2581 tttctgtttt atcattcttt acgcgtttgg ctaaaggttc ttcatccttt tccttaaaac
     2641 tggcagcata ggtttcaacc aaacatcgta atgcaagatc tgcaaacaca atcatgtgcc
     2701 ccccaccaaa ccacatcatc tttaaagttc aataagcagt atggttaata caaaacgcaa
     2761 cacaagccat caaaaatata gctagctata tattgtaaca attctatcag atattataca
     2821 attttccatc ttaatttttc tagtgattta tttgcccaat aaaattattt taaat
//
