LOCUS       NM_001014053            1280 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus leucine rich repeat containing 26 (Lrrc26), mRNA.
ACCESSION   NM_001014053 XM_231053
VERSION     NM_001014053.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1280)
  AUTHORS   Evanson,K.W., Bannister,J.P., Leo,M.D. and Jaggar,J.H.
  TITLE     LRRC26 is a functional BK channel auxiliary gamma subunit in
            arterial smooth muscle cells
  JOURNAL   Circ Res 115 (4), 423-431 (2014)
   PUBMED   24906643
  REMARK    GeneRIF: Study indicates that arterial myocytes express LRRC26
            which functions as BK channel gamma subunit.
REFERENCE   2  (bases 1 to 1280)
  AUTHORS   Yan,J. and Aldrich,R.W.
  TITLE     BK potassium channel modulation by leucine-rich repeat-containing
            proteins
  JOURNAL   Proc Natl Acad Sci U S A 109 (20), 7917-7922 (2012)
   PUBMED   22547800
REFERENCE   3  (bases 1 to 1280)
  AUTHORS   Yan,J. and Aldrich,R.W.
  TITLE     LRRC26 auxiliary protein allows BK channel activation at resting
            voltage without calcium
  JOURNAL   Nature 466 (7305), 513-516 (2010)
   PUBMED   20613726
REFERENCE   4  (bases 1 to 1280)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC061729.1.
            
            On Apr 20, 2005 this sequence version replaced XM_231053.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC061729.1, DN948658.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMN16676784
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1280
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p13"
     gene            1..1280
                     /gene="Lrrc26"
                     /gene_synonym="RGD1308398"
                     /note="leucine rich repeat containing 26"
                     /db_xref="GeneID:311803"
                     /db_xref="RGD:1308398"
     exon            1..809
                     /gene="Lrrc26"
                     /gene_synonym="RGD1308398"
                     /inference="alignment:Splign:2.1.0"
     CDS             125..1129
                     /gene="Lrrc26"
                     /gene_synonym="RGD1308398"
                     /note="leucine-rich repeat-containing protein 26; BK
                     channel auxilliary gamma subunit LRRC26; BK channel
                     auxiliary gamma subunit LRRC26"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 26
                     precursor"
                     /protein_id="NP_001014075.1"
                     /db_xref="GeneID:311803"
                     /db_xref="RGD:1308398"
                     /translation="MRGSFFSRLPPQLSLLLLLLLLLSWRRVWTQEHIGTDPSKSPVA
                     PVCPEACSCSPGGKANCSALALPAVPAGLSWQVRSLLLDRNRVSTLPPGAFADAGALL
                     YLVLRENRLRSVHARAFWGLGVLQRLDLSSNQLETLSPGTFTPLRALSFLSLAGNRLA
                     LLEPSILGPLPLLRVLSLQDNSLSALEAGLLNSLPALDVLRLHGNPWACSCALRPLCT
                     WLRKHPRPTSETETLLCVSPKLQTLNLLTDFPDNAFKQCTQSLAARDLAVVYALGPAS
                     FLASLAICLALGSVLTACGARRRRRRTTVRHLIRRQPDPEGPASLEDVGSPTTTAIQA
                     "
     exon            810..1251
                     /gene="Lrrc26"
                     /gene_synonym="RGD1308398"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaaactgttt tgctagggcg ggagagttaa tacttgtgca ggtgaggcag ggacaagctc
       61 tgggtcacct gaactccgaa gccacacagg gatcaaggtc ccctcctgtt ctcgagctgc
      121 ctccatgagg ggttcttttt tctcgcggct tccgccgcaa ctctctctgc tgctgctgct
      181 gctgctgctg ttgtcgtgga gacgagtctg gacccaggag cacattggaa ctgacccttc
      241 caaatccccg gtggcccccg tatgccccga ggcatgttca tgttcaccag gaggcaaggc
      301 caattgctcc gcgctggcgc tgcccgcggt accggcgggc ctgagctggc aagtacgctc
      361 actgctgctg gatcgcaatc gagtgagcac actacctcca ggtgccttcg ccgatgcagg
      421 cgcactgcta tacctagtcc tgcgggagaa ccggcttcgg tcggtgcacg cgcgagcttt
      481 ctggggtctg ggagtgttgc aacggctgga cctgagctcc aaccagctgg aaactctgtc
      541 tcctggcacc ttcacgcctc tgcgagcgct gagtttcctc tccctagcgg gtaaccggct
      601 ggcactcctg gagccctcga tcctgggccc gctcccttta ctgcgggtgc tcagcctgca
      661 ggacaattca ctatcggcac tcgaggcggg tttgctgaat agcttgcctg ccctcgacgt
      721 gttgcgcttg catggcaacc cctgggcgtg cagctgcgcg ctgcgcccgc tttgcacctg
      781 gctgcgtaag cacccgcgtc ccacttcaga aactgagacc ctgctctgtg tgtctccaaa
      841 acttcaaacg ctcaacctac tgacagactt tccggacaac gccttcaaac agtgcacgca
      901 gtcactcgct gcgcgagacc tggcggtggt ctatgctctc gggccggcct ctttccttgc
      961 cagtttagcc atctgcctgg cattgggctc ggtactcact gcttgtggtg cacggcgccg
     1021 ccgccgccgc accacagtgc gccacttaat aaggagacag ccagaccccg agggcccagc
     1081 ctccctggag gatgttggga gccctacaac aacagctatc caagcctaag ggttccgctg
     1141 ttgtttctag cgctcctgta gcatcccgca ctttgaaaac tgtccccaaa tccccgatcc
     1201 tcccttcaca ttccctgtag gcgtcaacaa tagacaaaac ccggaaattt taaaaaaaaa
     1261 aaaaaaaaaa aaaaaaaaaa
//
