LOCUS       NM_001393940            3542 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus leucine rich repeat containing 2 (Lrrc2),
            transcript variant 1, mRNA.
ACCESSION   NM_001393940 XM_017595599
VERSION     NM_001393940.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3542)
  AUTHORS   Tarantino C, Paolella G, Cozzuto L, Minopoli G, Pastore L, Parisi S
            and Russo T.
  TITLE     miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic
            stem cells
  JOURNAL   FASEB J 24 (9), 3255-3263 (2010)
   PUBMED   20439489
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000200.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001393940.2.
            
            On Mar 23, 2021 this sequence version replaced XM_017595599.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-137               JACYVU010000200.1  13894902-13895038
            138-284             JACYVU010000200.1  13901614-13901760
            285-492             JACYVU010000200.1  13905019-13905226
            493-649             JACYVU010000200.1  13906828-13906984
            650-786             JACYVU010000200.1  13910109-13910245
            787-932             JACYVU010000200.1  13919875-13920020
            933-1088            JACYVU010000200.1  13923450-13923605
            1089-1225           JACYVU010000200.1  13925253-13925389
            1226-3542           JACYVU010000200.1  13925656-13927972
FEATURES             Location/Qualifiers
     source          1..3542
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..3542
                     /gene="Lrrc2"
                     /note="leucine rich repeat containing 2"
                     /db_xref="GeneID:301033"
                     /db_xref="RGD:1311716"
     exon            1..137
                     /gene="Lrrc2"
                     /inference="alignment:Splign:2.1.0"
     exon            138..284
                     /gene="Lrrc2"
                     /inference="alignment:Splign:2.1.0"
     CDS             160..1275
                     /gene="Lrrc2"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 2"
                     /protein_id="NP_001380869.1"
                     /db_xref="GeneID:301033"
                     /db_xref="RGD:1311716"
                     /translation="MGHKVVVFDISVVRALWETRVKKHKAWQKKEAERLEKSALEKIK
                     EEWEFVAECRRKGVPQAEYCKNGFVDTSTRLLERIERNSVARQSARVKDRGKRSNPFV
                     FELSGTQWKELPDSLKEQTHLKEWHIHNTLIQIIPTYIELFHSMKILDLPKNQITCLP
                     PEIGRLKNLKELNVSFNHLKSIPPELGDCENLERLDCSGNLDLMELPFELSNLKQVTF
                     VDISANKFSSVPICVLRMCRLQWLDISSNDLTDLPQDIDRLEELQGFLLYKNKLTYLP
                     QAMLNLKKLTLLVVSGDDLVELPTALCDASTPLKFVSLLDNPIDKTRCQDTDDTVESE
                     QDRQHFDKEFMKAYIEDLKEREAVPSYTAKVSFSLQL"
     exon            285..492
                     /gene="Lrrc2"
                     /inference="alignment:Splign:2.1.0"
     exon            493..649
                     /gene="Lrrc2"
                     /inference="alignment:Splign:2.1.0"
     exon            650..786
                     /gene="Lrrc2"
                     /inference="alignment:Splign:2.1.0"
     exon            787..932
                     /gene="Lrrc2"
                     /inference="alignment:Splign:2.1.0"
     exon            933..1088
                     /gene="Lrrc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..1225
                     /gene="Lrrc2"
                     /inference="alignment:Splign:2.1.0"
     exon            1226..3542
                     /gene="Lrrc2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcaaaagca gttcctgaca ccaacaagaa gagtgtttgt ttacttggag attctaaacc
       61 caatcgagtt gactgtgaag acgaaccctt cggcgttccg tagctgaggc tgcgtggtac
      121 ttttgcacac tgttcaggta actttatgct gctccccaaa tgggacacaa agtggtcgtg
      181 tttgatatct ctgttgtcag agccttatgg gaaactcgtg tcaagaagca caaagcatgg
      241 cagaagaagg aggcggagag gctggagaaa agcgccctgg agaagataaa ggaggagtgg
      301 gaatttgtgg ccgagtgcag gaggaagggc gtgccccagg ctgagtactg caagaatggc
      361 ttcgtagaca ccagcacaag gctcctggaa aggatagaga ggaactcagt ggccaggcag
      421 agtgcacgag tcaaggacag aggcaaacgg agcaatccat tcgtgtttga actttcaggg
      481 acacagtgga aggagctgcc tgattcgctg aaggaacaga cacacctcaa agaatggcac
      541 attcacaaca ccctcattca gatcattcca acgtacattg agctgtttca ctcgatgaag
      601 attttggatt tgccaaagaa ccaaatcacg tgtcttcccc ccgaaatcgg tcgcttgaag
      661 aacctgaaag aactcaatgt gagtttcaac catttgaaga gtattccccc ggagctagga
      721 gactgtgaga atttagagag actagactgt tctgggaatc tggacctgat ggagctcccc
      781 tttgaattga gtaatctgaa acaggttacc tttgtggata tctcagcaaa caagttctcc
      841 agcgtcccga tctgtgtcct gcggatgtgt cgtctgcagt ggctggatat cagcagcaat
      901 gatctgactg acctgccaca agatatagac aggctggaag agctacaagg tttcctcctg
      961 tataaaaaca agctgaccta ccttcctcaa gccatgctca acctcaaaaa gctcaccctg
     1021 ctggttgtca gtggggatga cctggtggag ctcccgaccg ccctctgcga tgcctccacg
     1081 cctttgaaat ttgtaagcct tttggacaat cccattgaca agacccgatg tcaggacact
     1141 gacgacacag tagaaagcga acaggaccgc cagcacttcg ataaggaatt tatgaaagca
     1201 tacatcgaag accttaaaga aagagaagct gttcccagtt ataccgccaa agtgtcattt
     1261 agccttcaac tttgattcgc tccaccggaa gaccacaatg ccttactgcc ccgagctctg
     1321 aatctttgca tatgcgttac ctcttattgg aattgcgtct catgcttgag ggcaaagtct
     1381 atagaaacca ccatcatcac tgttaagaag aataacattc aattcattga taaatttgct
     1441 tctataccaa tgttaacagg ctaatgcaca tacttgtctt aaatactgcg tatttaatat
     1501 tttaggaaac acattactta aaaagtgacg acatacggaa cgggttttga aattggatgc
     1561 actgtgttca ggagtccagg gctagagggc tgtgaatgaa atagagaatt tacccccttg
     1621 aaaggggttc ggcacactgt tcgtctttat tgagaaaagc gctccctgag tctaaacaag
     1681 ttgctacttc cccactccga gttcaagtat gttttaagtt gtactttgac tcccaggaga
     1741 acctgaaggt ataacttggg tcttgaaggt ggaaagaaag gttggtatac gtagggcgtc
     1801 cggcgctagc cgctcagaca gtgggagcct gggaggatcc gaatactgtg ctctgtagtg
     1861 tcctggctag tcacctgctg gtcctcagaa caaagagcca aggagtgcct tcaggactcg
     1921 ttcctgtagg tgttggggac agtgtggaga cctcaccgat ggcttccaca tggggatcac
     1981 aggagggctc tgccccctgg agcgcacctg tgcgttggca ggagcccctg ggatgttaat
     2041 ttgcgcgggc caaggcaggg actccgtgtt cttgaagcac gtttacacca ctggaagaac
     2101 tctataaagc ttctattttt ataccagtgc ctcaggctaa agcaagcagg aagtggctgg
     2161 ttgctctgaa gagaagaagg aaagacacat gtatcgactg tttgtacgtg agtggactcc
     2221 ttctgggtgt agtccagtgc agcccgccgc agccttcaca tggggaaaac gttctgtgcc
     2281 tgtgttgtta ggtgccataa tgtccagaga tggaacacgt agtgtctgac aagctttgaa
     2341 aactaagttt tatttatttt tcttttcttt ttttcggagc tggggactga acccagggcc
     2401 ttgcgcttgc taggcaagca ctctaccact gagctaaatc cccaaccccg aaaactaagt
     2461 tttaaatgca acttccttaa agagtcactt gtggctaccg aactgtacag taaggcctaa
     2521 cctgccaggt tggggtggga gggcgatgtc tgtggttata aaataaatga atggggttgg
     2581 ggatttggct cagtggcaga gcacttgcct aggaagcgca aggccctggg ttcggtcccc
     2641 agctccgaaa aaaagaacca aataaataaa taaataaata aataaataaa taataaatga
     2701 ataagtaaat aagtaagtaa ataagggggt aatttttact ctttttaacc tgaagaactg
     2761 atttgctctc agaatcatat aatttaaaaa ggttatcaca tacacataat taaaaaaaaa
     2821 aaacaaggct aggagatggc tcagaggtta aaagtgttac tacttaaatc taagaaccca
     2881 gtgcaaactg gttagctggc caagcctacc ggaagctctt gttttgaata ggagatgccg
     2941 ccccagtaac tgaagtggaa aggtgccaga ggatgattca aactctggcc tctccatgga
     3001 cacacacacc caggtgcacc ccacacacat gcgaaaatac cacacacgcg cacactcacg
     3061 gaaagtggga agaggaaaga ttagtaatgg tgtttcggta ttttcgcctt tcgcctgccg
     3121 cggttcgaat gaggcccgag cgtttttatc attggtctca gcagagcgtc acttcaacgg
     3181 aaagcaaagt gtccagaggc aggctaaagg gcgaaacgtc ttttgtcccg acacttaacg
     3241 ctgtttcaaa ttgatgacta gtcctacttg agtgactgct ggattttttt tttttttttt
     3301 ttttggttct tcttttcgga gctggggatc gaacccaggg ccttgcgctt cctaggcaag
     3361 cgctctacca ctgagctaaa tccccaaccc cgactgctgg attttattcc atactcaagg
     3421 acatgcctca tatcaagata tgaaaactaa atatgaaaag atgaaagtgt agaatttcac
     3481 acaaatggac tgttcataat ttatgtaagt tttattttaa taaaaccagc ctttgcgtaa
     3541 aa
//
