LOCUS       NM_001109413            3809 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus leucine rich repeat containing 19 (Lrrc19), mRNA.
ACCESSION   NM_001109413 XM_001054554
VERSION     NM_001109413.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3809)
  AUTHORS   Cao,S., Su,X., Zeng,B., Yan,H., Huang,Y., Wang,E., Yun,H.,
            Zhang,Y., Liu,F., Li,W., Wei,H., Che,Y. and Yang,R.
  TITLE     The Gut Epithelial Receptor LRRC19 Promotes the Recruitment of
            Immune Cells and Gut Inflammation
  JOURNAL   Cell Rep 14 (4), 695-707 (2016)
   PUBMED   26776522
REFERENCE   2  (bases 1 to 3809)
  AUTHORS   Chai,L., Dai,L., Che,Y., Xu,J., Liu,G., Zhang,Z. and Yang,R.
  TITLE     LRRC19, a novel member of the leucine-rich repeat protein family,
            activates NF-kappaB and induces expression of proinflammatory
            cytokines
  JOURNAL   Biochem Biophys Res Commun 388 (3), 543-548 (2009)
   PUBMED   19679103
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Sep 8, 2022 this sequence version replaced NM_001109413.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643288.22743.1,
                                           SRR26643287.13508.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-108               JAXUCZ010000005.1  114623575-114623682 c
            109-189             JAXUCZ010000005.1  114618151-114618231 c
            190-703             JAXUCZ010000005.1  114616702-114617215 c
            704-868             JAXUCZ010000005.1  114614213-114614377 c
            869-3809            JAXUCZ010000005.1  114610625-114613565 c
FEATURES             Location/Qualifiers
     source          1..3809
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q33"
     gene            1..3809
                     /gene="Lrrc19"
                     /note="leucine rich repeat containing 19"
                     /db_xref="GeneID:680478"
                     /db_xref="RGD:1591722"
     exon            1..108
                     /gene="Lrrc19"
                     /inference="alignment:Splign:2.1.0"
     exon            109..189
                     /gene="Lrrc19"
                     /inference="alignment:Splign:2.1.0"
     CDS             118..1197
                     /gene="Lrrc19"
                     /note="leucine-rich repeat-containing protein 19"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 19
                     precursor"
                     /protein_id="NP_001102883.1"
                     /db_xref="GeneID:680478"
                     /db_xref="RGD:1591722"
                     /translation="MKVTRFMFWLFSMLLSDKSQASETEVKCNFTRKNYALIPEGISS
                     NVTILDLSYNQITLNASDTRTLQMYSLLTELYLMENNITALYNNTFSNLLNLEILNIC
                     GNSISVIQQGSFVGLNELKQLFLCQNKILQLTPDTLVPLNNLKVLDLRGNLISLFHAP
                     RLSHLELLTLDGNPWNCTCGLLDLQNWLNTSNVTLENESITTCNYPDDLKHYSIKSAP
                     FTTECHSKFISTIAEDLYIDFNRSLKNLTWNSEHEPLGKSWAFLVGVVATVLLTSLLI
                     FIAIKCPIWYNILLSYNHHRLEEHEAETYDQGLTRNPSSLSQITDTNSEDNTVIFEQL
                     HSFVVDDDGFIEDRYIDINEVHEEK"
     exon            190..703
                     /gene="Lrrc19"
                     /inference="alignment:Splign:2.1.0"
     exon            704..868
                     /gene="Lrrc19"
                     /inference="alignment:Splign:2.1.0"
     exon            869..3809
                     /gene="Lrrc19"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaaactgtgg aatgcaacca tctgacacag gcttttctaa tggtgtagga gaagcagagt
       61 aaactcctcg aacacacctg tctcagacag aaaaaggaga aagtaaaggc ctttgatatg
      121 aaagtcacac gcttcatgtt ttggcttttc tccatgctac tatccgacaa aagccaggct
      181 tctgaaactg aagtcaaatg taatttcacc agaaagaatt atgctttgat tccagagggc
      241 atcagtagca atgttaccat ccttgatctc agttataacc aaattactct gaatgcttca
      301 gacaccagga cgctacagat gtactcttta ctcaccgagc tttacttgat ggagaacaac
      361 atcacggcct tatataacaa tacgttcagt aatctcctca acctagaaat tttaaatatc
      421 tgtggaaatt caatcagtgt aattcaacag ggttcatttg ttggtttaaa tgagctaaaa
      481 caattatttc tttgccaaaa caaaatatta caactaactc ctgatacact tgtgcctcta
      541 aacaacctga aagttctgga tcttcgaggc aatctgataa gcctcttcca tgcaccacgg
      601 ctatctcatc tggagttgct aactctggac ggaaatccat ggaactgtac ctgtggtcta
      661 cttgacttgc agaactggct aaacacgtct aatgtgacat tagaaaacga gagcatcacc
      721 acgtgtaact acccagatga cctaaagcac tacagcatta agtcggcacc ctttacaact
      781 gaatgccact ctaaatttat ttctactata gctgaagacc tttatattga ttttaataga
      841 tctttaaaga acttaacgtg gaactcagag catgagcctc tggggaaaag ctgggctttc
      901 ctggtcggcg ttgtcgccac tgtcctgcta acctcactgc tcatcttcat tgctatcaag
      961 tgtccaatat ggtacaatat tctgctgagt tacaaccatc atcgcctaga agagcacgaa
     1021 gcagaaacct atgaccaagg ccttacaaga aacccaagtt ctctttcaca gataacagat
     1081 accaactctg aagacaacac agtaatattt gaacagttgc attcatttgt ggtagacgat
     1141 gatgggttta ttgaagacag atacatagat atcaatgagg tacatgaaga aaagtaattt
     1201 tatcatgttg aaattttgaa aatagcttag acaaaaagat ttttatttgg ccaacaaaac
     1261 tataaccagt agaccttcat attaattagt actttatata aatatcagtt actatttttt
     1321 actgtattgc acaaaaaagt ccaaatccaa taactcatat actagttagc taaaagttta
     1381 ataatttacc tatactacca gcaattacta gtgtcagcag tgttcaggaa actacagact
     1441 gataaaaaca aggccaaagg acaattatca actaaaatga acaaattctg gtattaacaa
     1501 atacacttgc tgagatgcct taaattatac tgaaatttta atcaataaaa aaatataaat
     1561 ttaaaaatga ggaacgggag ctttaactat ataatttggt gttatgttca caaatgaatt
     1621 cacagaatga gaatattttc taatgctgtc tgaacttaaa aaacaaaatt tccggggttg
     1681 gggatttagc tcagtggtag agcgcttgcc taggaagcgc aaggccctgg gtttggtccc
     1741 cagctccgaa aaaaagaacc aaaaaaaaaa aatttcctta aaattttgta gtaattttaa
     1801 agcacagggg caataatttg gaataacccc ttactaatca ctactgtctg tatttgacaa
     1861 taattgttaa gaagagttcc acatataatt gccatactta atattataat ggctcctaaa
     1921 ctaggcatca taactaatta tgaattttct ttaaaagaag aaaacagttc tctacttctt
     1981 ttgggagatt atttctaaaa caattctgag ctagaactga gaatatttaa gtgctcccaa
     2041 tacatctctg tttcaataaa cagagcaatg tttcccaaat tgttttctag gacactgatt
     2101 ttctgcaata acactgacaa gcatttatag agaaaggaaa aggtacctgg tcaaattact
     2161 aaaagaattt aaatctaaac atgatgaaag attttttttt cctttagtac ttatatagat
     2221 tttactaagt tcaggtgttc tctgataact caggagtaca gtactgagtt tttgaagcgc
     2281 atctgcatag catgtgcaaa tccctaagtc cctgggtttc ctccccccca cccttcttcc
     2341 ctccctgtgt gtctgtgagt gtgtgtgtgt gatatataca cacacactca catacacaga
     2401 cacacacaga aatgtcaaaa tttatttaat aaaccctttc ttgaaagaat aactaatagt
     2461 ttacagcata ttaatagatc aaaagacaca ttctggaaaa aaaatcccta acataggaag
     2521 ggtctatcta aagtgagatg tttaccaatt ctcttatagt agctgagcta caaatatgat
     2581 ttgaacaact taacagttta gagtagaatt aaaaatcagc aaaatctgta ttttaccatt
     2641 ctatatgtgg aaaaactaag tgtatttatt tgcatctttt agagataaag cgatctgtaa
     2701 aacagtgaac tatacttatg aagtagtgta acacacttct gtgattttct ttgtctgcat
     2761 acatgggaag ggagagtggc cagagctgaa gatcgaacag ctagaaatgt gatgacacaa
     2821 caatcatgtg atgatacatg agtatacaat gctctgatgt ccagtttccc ttcaataaag
     2881 atattcaaaa caatgtacat gataccttct tttaaaaaag actaataatg aagatctatc
     2941 cataatctgc aaataatact catcaatgac aatgtataaa gcctactgat cgattactcc
     3001 tttcattaaa gtggaactaa aggtcataat tcaatctagt taaaagcctg ggttaaaatt
     3061 ctaagtggca gatataaaaa cataattcat cttagagttt aagtctttag aagcagaaat
     3121 catatttata gaactgggta gtcctttcct ttgtataaaa tttagctcct tgggagtaaa
     3181 taagacagca tatatttgac aattagataa attttctatt aagatgttat ggtagattaa
     3241 gaaaagatga tacattttct attacaaata tatactttaa atgagagttc agtaagatgc
     3301 cagctgtggt tcctgcctgt ggttccagca cttgggaggc tgaggcagaa ggatccttgt
     3361 gagtctgaga tagcctacac tacagaggac gataccgact catgagaatc caacaattaa
     3421 gggctggaga gatggctcag gggttgggag cactgggtgc tcttccggat gcccacatgg
     3481 cagctcacag gtctctgtgg ctcagtgcca ggggctccaa tgcccttgca cagacataga
     3541 cacaggcaga acgccagtgc acatgaaata aaaataaata aaagtttaat caacaattaa
     3601 caaaaaagca aaataagaga aaaagttaaa attttataag gaaacgattc acaagttaaa
     3661 ccatctacca aaactcgttt atacatgtga acttacgctt gtctttcggt aaatatgaca
     3721 tccatacttt gtgtttctcg atcattttga gctttaagct gtataaacaa ttaacacaga
     3781 cattattcat tagaaaaatg gtaaccacc
//
