LOCUS       NM_001401224            2370 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus leucine rich repeat containing 14 (Lrrc14),
            transcript variant 1, mRNA.
ACCESSION   NM_001401224 XM_006241860
VERSION     NM_001401224.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2370)
  AUTHORS   Wu,C., Yang,Y., Ou,J., Zhu,L., Zhao,W. and Cui,J.
  TITLE     LRRC14 attenuates Toll-like receptor-mediated NF-kappaB signaling
            through disruption of IKK complex
  JOURNAL   Exp Cell Res 347 (1), 65-73 (2016)
   PUBMED   27426725
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Feb 4, 2022 this sequence version replaced XM_006241860.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.32047.1,
                                           SRR26643285.28583.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-429               JAXUCZ010000007.1  110311394-110311822
            430-783             JAXUCZ010000007.1  110315526-110315879
            784-1368            JAXUCZ010000007.1  110316072-110316656
            1369-2370           JAXUCZ010000007.1  110316756-110317757
FEATURES             Location/Qualifiers
     source          1..2370
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..2370
                     /gene="Lrrc14"
                     /note="leucine rich repeat containing 14"
                     /db_xref="GeneID:500900"
                     /db_xref="RGD:1560202"
     exon            1..429
                     /gene="Lrrc14"
                     /inference="alignment:Splign:2.1.0"
     CDS             326..1936
                     /gene="Lrrc14"
                     /note="isoform 1 is encoded by transcript variant 1;
                     leucine-rich repeat-containing protein 14"
                     /codon_start=1
                     /product="leucine-rich repeat-containing protein 14
                     isoform 1"
                     /protein_id="NP_001388153.1"
                     /db_xref="GeneID:500900"
                     /db_xref="RGD:1560202"
                     /translation="MNHRRDRCVLCAVASPRSNFFLGTRPAAFVSSYDRGLSAQSSTM
                     HTLVFLSTRQVLQCQPAACQALPLLPRELFPLLFKVAFMDKKTAVLRELVHTWPFPLL
                     SFQQLLQECAHCSRALLQERLSTESMQAVILGLTARIHAREAEAGTQPVCRKHTLRVL
                     DMTGLLDDGVEQDPGTMSMWDCTAAVARTCIAQQQVGTAKPGLSPVPVEIRVDLRVNR
                     ASYTFLREALQSSVDSLLRLCCRDLRAEDLPMRNTVALLQLLDAGCLRRIDLRFNNLG
                     LRGLSVIIPHVARFQHLASLRLHYVHGDSRQPSVDGEDNFRYFLAQMGRFICLRELSI
                     GSSLLSGRLDQLLSTLQRPLESLELAFCALLPEDLRFLAQSSHAAHLKKLDLSGNDLS
                     GNQLTPFQGLLQAVAATLLHLELTECQIADAQLLATLPTLTRCASLRYLGLYGNPLSM
                     AGLKELLRDSVIQAELRTVVHPFPVDCYEGLPWPPPASVLLEASINEEKFARVEAELH
                     QLLLASGRAHVLWTTDIYGRLAADYFNL"
     exon            430..783
                     /gene="Lrrc14"
                     /inference="alignment:Splign:2.1.0"
     exon            784..1368
                     /gene="Lrrc14"
                     /inference="alignment:Splign:2.1.0"
     exon            1369..2370
                     /gene="Lrrc14"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcttgctggg cgaggggagg ggttggaggc cttggtagtg ggggcggatg agctggggcc
       61 cgggggttgg tattcgagct gtgctaggag tcagcagccg ttaatggtca gggcattcgg
      121 acggcaggtt cgacgaggac tgacgcttga aggccacagc tgaggcggat tctcgggagg
      181 tgccgctgcg cgcgcgggaa tgggccgcaa gcgcagggcg acctaggggc gggtgagaac
      241 gttctcggcc tgtaaaaaca ggctcgcctg gattagttga agttccgggc tttttttctc
      301 gaaggacccg agcgtgcgcg tccatatgaa tcaccgccga gaccgctgtg tcctgtgtgc
      361 agtagcatca cccagaagca attttttctt ggggaccagg ccggctgctt tcgtttcctc
      421 ttatgacagg ggcctgtctg cccagtccag caccatgcac acgcttgtgt tcctcagcac
      481 acgccaggtg cttcagtgcc agccagctgc ctgccaggcc ttgcccctgc tgccccgaga
      541 actcttccct ctgctgttca aggtggcctt catggacaag aagacagccg tgctgcgtga
      601 gctggtgcac acgtggccct ttcccctcct cagtttccag cagctgctgc aggagtgtgc
      661 ccactgcagt cgagccctgc tgcaggaacg gctcagcaca gaaagcatgc aggctgtgat
      721 cctgggactg accgcccgga tacatgctcg agaagcagag gctggcacac agcccgtttg
      781 caggaagcat acactgcggg tactggacat gactggcctc ctggatgatg gtgtggagca
      841 ggatccagga accatgagca tgtgggactg tacagcggcg gtagccagaa cttgtattgc
      901 ccagcagcag gtcgggactg ctaagccagg gctgtcacca gtccccgtgg aaattcgtgt
      961 agaccttcgg gtaaaccggg cctcctatac attccttcgt gaggcactcc agagtagtgt
     1021 ggacagcctg ctgcggctct gctgccggga cctccgggct gaggatctgc ccatgcgtaa
     1081 cactgtggcc ctactacagc ttctagatgc aggctgtctg cgccgtatag acctgcgctt
     1141 caataacctg ggcttgcgtg gcctgtctgt cattatccca catgtggccc gctttcagca
     1201 cctagccagc ctgaggctgc attatgtgca tggggactcc agacagccct ccgtggatgg
     1261 tgaggacaac tttcgctact tcctggccca gatgggccgg ttcatctgtc ttcgggagct
     1321 cagcattggc tcttctctcc tctcaggcag gctggatcaa ctgctcagca ccctgcagag
     1381 gcccctggaa agcctagagc tggccttctg tgcactgttg cctgaggacc tacgcttcct
     1441 ggctcagagc tctcatgctg cccacctcaa aaagctggac ttgagtggca atgacttgtc
     1501 aggcaaccag ctgacaccct tccagggtct gctgcaggca gtagcagcca cactgctgca
     1561 tcttgagctg actgagtgcc agattgctga tgcccagttg ttggccacac tgcccaccct
     1621 gactcgctgt gccagtctcc gataccttgg tctctatggc aaccctttgt ctatggcagg
     1681 acttaaagag ctgcttcggg actctgtgat tcaggctgag ctacgtactg tggtgcaccc
     1741 tttccctgtg gactgctatg agggtcttcc ttggccgcca cctgcctctg tccttctgga
     1801 agcctccatc aatgaggaga agtttgcccg tgtagaagct gagttacacc agctgctgtt
     1861 agcttcaggc cgtgcccatg tactctggac cacagacatc tatggccggc tggctgcaga
     1921 ctattttaac ctctgatctc caggtcttgg tgaagtctta ggttttctgc agagtttgcc
     1981 tttctcctgg gtacaccttg agtcacctct actttctgca gtgtccttca cctgcttatc
     2041 tggctgcctc tcggtgtctc aggcctgtgc tcccctgttc tgtatgatgt acttgatggc
     2101 tctgctgagt tgcggtgtct ctgtagaaaa cggttcctgg acacatccca tgccctcagc
     2161 aggggtgcag tacattgagg tagatgttag gatgatctgc tccagggcat ctttgggtct
     2221 tatactgtgt accctgcctg gcaccctagt acctggctct ggagggtgtg agtaaggtac
     2281 aaatgtgcag tatctgaaat gtgaatttat gggctttttg atgtgtgtgt cctaattgga
     2341 tgggaaagac ttacctgctt ttctagtgtt
//
