LOCUS       NM_001008519            4361 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus leucine-rich pentatricopeptide repeat containing
            (Lrpprc), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001008519 XM_233832
VERSION     NM_001008519.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4361)
  AUTHORS   Natalizio,B.J. and Wente,S.R.
  TITLE     Postage for the messenger: designating routes for nuclear mRNA
            export
  JOURNAL   Trends Cell Biol 23 (8), 365-373 (2013)
   PUBMED   23583578
  REMARK    Review article
REFERENCE   2  (bases 1 to 4361)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 4361)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   4  (bases 1 to 4361)
  AUTHORS   Ruzzenente,B., Metodiev,M.D., Wredenberg,A., Bratic,A., Park,C.B.,
            Camara,Y., Milenkovic,D., Zickermann,V., Wibom,R., Hultenby,K.,
            Erdjument-Bromage,H., Tempst,P., Brandt,U., Stewart,J.B.,
            Gustafsson,C.M. and Larsson,N.G.
  TITLE     LRPPRC is necessary for polyadenylation and coordination of
            translation of mitochondrial mRNAs
  JOURNAL   EMBO J 31 (2), 443-456 (2012)
   PUBMED   22045337
REFERENCE   5  (bases 1 to 4361)
  AUTHORS   Xu,F., Addis,J.B., Cameron,J.M. and Robinson,B.H.
  TITLE     LRPPRC mutation suppresses cytochrome oxidase activity by altering
            mitochondrial RNA transcript stability in a mouse model
  JOURNAL   Biochem J 441 (1), 275-283 (2012)
   PUBMED   21880015
REFERENCE   6  (bases 1 to 4361)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   7  (bases 1 to 4361)
  AUTHORS   Mili,S. and Pinol-Roma,S.
  TITLE     LRP130, a pentatricopeptide motif protein with a noncanonical
            RNA-binding domain, is bound in vivo to mitochondrial and nuclear
            RNAs
  JOURNAL   Mol Cell Biol 23 (14), 4972-4982 (2003)
   PUBMED   12832482
REFERENCE   8  (bases 1 to 4361)
  AUTHORS   Mootha,V.K., Lepage,P., Miller,K., Bunkenborg,J., Reich,M.,
            Hjerrild,M., Delmonte,T., Villeneuve,A., Sladek,R., Xu,F.,
            Mitchell,G.A., Morin,C., Mann,M., Hudson,T.J., Robinson,B.,
            Rioux,J.D. and Lander,E.S.
  TITLE     Identification of a gene causing human cytochrome c oxidase
            deficiency by integrative genomics
  JOURNAL   Proc Natl Acad Sci U S A 100 (2), 605-610 (2003)
   PUBMED   12529507
REFERENCE   9  (bases 1 to 4361)
  AUTHORS   Liu,L., Amy,V., Liu,G. and McKeehan,W.L.
  TITLE     Novel complex integrating mitochondria and the microtubular
            cytoskeleton with chromosome remodeling and tumor suppressor RASSF1
            deduced by in silico homology analysis, interaction cloning in
            yeast, and colocalization in cultured cells
  JOURNAL   In Vitro Cell Dev Biol Anim 38 (10), 582-594 (2002)
   PUBMED   12762840
REFERENCE   10 (bases 1 to 4361)
  AUTHORS   Tsuchiya,N., Fukuda,H., Sugimura,T., Nagao,M. and Nakagama,H.
  TITLE     LRP130, a protein containing nine pentatricopeptide repeat motifs,
            interacts with a single-stranded cytosine-rich sequence of mouse
            hypervariable minisatellite Pc-1
  JOURNAL   Eur J Biochem 269 (12), 2927-2933 (2002)
   PUBMED   12071956
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Jun 3, 2021 this sequence version replaced NM_001008519.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY293808.1, SRR26643298.34100.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-209               JAXUCZ010000006.1  15612638-15612846
            210-403             JAXUCZ010000006.1  15624835-15625028
            404-526             JAXUCZ010000006.1  15626242-15626364
            527-648             JAXUCZ010000006.1  15628019-15628140
            649-707             JAXUCZ010000006.1  15628240-15628298
            708-794             JAXUCZ010000006.1  15629224-15629310
            795-921             JAXUCZ010000006.1  15629858-15629984
            922-1066            JAXUCZ010000006.1  15630420-15630564
            1067-1212           JAXUCZ010000006.1  15630979-15631124
            1213-1318           JAXUCZ010000006.1  15631341-15631446
            1319-1426           JAXUCZ010000006.1  15631530-15631637
            1427-1545           JAXUCZ010000006.1  15634097-15634215
            1546-1639           JAXUCZ010000006.1  15636880-15636973
            1640-1706           JAXUCZ010000006.1  15639624-15639690
            1707-1734           JAXUCZ010000006.1  15646526-15646553
            1735-1792           JAXUCZ010000006.1  15648280-15648337
            1793-1899           JAXUCZ010000006.1  15649368-15649474
            1900-1977           JAXUCZ010000006.1  15649688-15649765
            1978-2022           JAXUCZ010000006.1  15650109-15650153
            2023-2136           JAXUCZ010000006.1  15650437-15650550
            2137-2267           JAXUCZ010000006.1  15651310-15651440
            2268-2353           JAXUCZ010000006.1  15652076-15652161
            2354-2561           JAXUCZ010000006.1  15653690-15653897
            2562-2686           JAXUCZ010000006.1  15661828-15661952
            2687-2793           JAXUCZ010000006.1  15662376-15662482
            2794-2862           JAXUCZ010000006.1  15670571-15670639
            2863-2953           JAXUCZ010000006.1  15671291-15671381
            2954-3096           JAXUCZ010000006.1  15676362-15676504
            3097-3205           JAXUCZ010000006.1  15676625-15676733
            3206-3332           JAXUCZ010000006.1  15679191-15679317
            3333-3421           JAXUCZ010000006.1  15683902-15683990
            3422-3623           JAXUCZ010000006.1  15687517-15687718
            3624-3763           JAXUCZ010000006.1  15689545-15689684
            3764-3879           JAXUCZ010000006.1  15689813-15689928
            3880-3954           JAXUCZ010000006.1  15692017-15692091
            3955-4039           JAXUCZ010000006.1  15693111-15693195
            4040-4182           JAXUCZ010000006.1  15694181-15694323
            4183-4361           JAXUCZ010000006.1  15694935-15695113
FEATURES             Location/Qualifiers
     source          1..4361
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q12"
     gene            1..4361
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /note="leucine-rich pentatricopeptide repeat containing"
                     /db_xref="GeneID:313867"
                     /db_xref="RGD:1306575"
     exon            1..209
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     CDS             61..4239
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /note="leucine-rich PPR motif-containing protein,
                     mitochondrial; leucine-rich protein 157; LRP 130; rLRP157;
                     130 kDa leucine-rich protein; leucine-rich PPR-motif
                     containing"
                     /codon_start=1
                     /product="leucine-rich PPR motif-containing protein,
                     mitochondrial precursor"
                     /protein_id="NP_001008519.2"
                     /db_xref="GeneID:313867"
                     /db_xref="RGD:1306575"
                     /translation="MSALLRPARWLLGAAAVPRLPLSLRLPAGGPGRLPSVVRVAAAG
                     GRPAAGELLSQARLYAIVAEKKDLPEEPAPVRRSGSQFDWALMRLDNSVRRTGRITKG
                     LLQKVFESTCRSGSPGSNQALLLLRSCGSLLPELSLAERTEFAHKIWDKLQQLGTVYD
                     VSHYNALLKVYLQNEYRFSPTDFLAKMEGANIQPNRVTYQRLIAAYCSVGDIEGASKI
                     LGFMKTRDLPITEAVFSALVTGHARAGDMENAENILTVMKQAGIEPGPDTYLALLNAH
                     AEKGDIDHVKQILEKVEKSDHYFMDRDFLQIIVSFSKAGYPQYVSEILEKITYERRSI
                     PDAMNLILLLVTEKLEDTAFQVLLALPLARDETSSSFGSFFLRHCVTMDTPAEKLIDY
                     CKRLRDAKVHSSSLQFTLHCALQANKTALAKAVMEALRDEGFPIRTHYFWPLLVGHQK
                     TKNVQGIIDILKIMKEMGVDPDQETYINYVFPCFGSVQSARAALQENKCLPKSTTFAQ
                     AEVRNEAINGNLQNILSFLESNALPFSFNSLRGSLILGFRRSMNIDLWSKITELLYKD
                     DRYCQKPPGPTEAVGYFLYNLIDSMSDSEVQAKEERLRQYFHQLREMNVKVSENIYKG
                     ICNLLDNYHVPELIKDVKVLVDREKIDSRKTSQFTSSDLESTLEKLKAEGHPVGDPLK
                     QLILLLCSEENMQKALEVKAKYESDMVIGGYAALINLCCRHDNAEDALNLKQEFDRLD
                     PSAVLDTAKYVALVKVLGKHGRVQDAINILKEMKEKDVVIKDAAVLSFFHILNGAALR
                     GEIETVKQLHEAIVTLGLAKPSSNISFPLVTVHLEKDDLPAALEASIACHEKYKVLPR
                     IHDVLCKLIEKGETDLIQKAMDFVSQEQGEMSMLYDLFFAFLQTGNYKEAKKIIETPG
                     IRARPTRLQWFCDRCIANNQVETLEKLVELTEKLFECDRDQMYYNLLKLYKISGDWQR
                     ADAVWNKMQEENLIPRERTLRLLAGILKTSNQEVPFDVPELWFGDDRSSLSSSSPSAG
                     DTVTEKMLLSDCRLKKSKDAYNIFLKAEKQDVVFSSEAYSTLVGLLLSKDDFTRAMHV
                     KDFAETHIKGFTLNGAASSLLIIAQVRRDYLKVALETLKAALDLEQVPSELAVTRLIQ
                     ALALQGDVKSIETIQKMVKGLDAIELSRMVFINNIALAQMKNNEIDAAIENIEHMLAS
                     ENQTVEHQYFGLSYLFRKVIEEQMEPALEKLSIMSERLANQFALYKPVTDLFLQLVDS
                     GKVDEARALLERCGAIAEQTSILSVFCLRTSQKPKKAPVLKTLLELIPELRENDRVYS
                     CSMKSYVADKDVASAKALYEHLTAKNMKLDDLFLKRYASLLKDVGEPVPFTEPPESFG
                     FYIKQLKEARENPS"
     exon            210..403
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            404..526
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            527..648
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            649..707
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            708..794
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            795..921
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            922..1066
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            1067..1212
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            1213..1318
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            1319..1426
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..1545
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            1546..1639
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            1640..1706
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            1707..1734
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            1735..1792
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            1793..1899
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            1900..1977
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            1978..2022
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            2023..2136
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            2137..2267
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            2268..2353
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            2354..2561
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            2562..2686
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            2687..2793
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            2794..2862
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            2863..2953
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            2954..3096
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            3097..3205
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            3206..3332
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            3333..3421
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            3422..3623
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            3624..3763
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            3764..3879
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            3880..3954
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            3955..4039
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            4040..4182
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
     exon            4183..4361
                     /gene="Lrpprc"
                     /gene_synonym="Lrp157"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcacgtgtt cctccaggtc ctctgcagga gcgtgcatcc tgccttgact acggtgaacc
       61 atgtcagccc tgctgagacc cgcgcgttgg ctgctagggg cagcggcggt cccgcgcctc
      121 ccgctgtccc tgcgcctccc tgcgggcggc cccggcaggc tgccctctgt cgtccgggtg
      181 gcggccgctg gtggccggcc ggctgcagga gagctgctga gccaagccag gttgtatgcc
      241 atcgtcgctg aaaaaaagga tcttccagag gagcctgctc ctgtgagaag gagtggcagt
      301 cagtttgatt gggccctaat gagactggat aattctgtcc ggagaacggg ccgcattacc
      361 aaggggcttc tgcagaaagt ctttgagagc acgtgccgct cagggagccc agggagtaac
      421 caggccttgc ttctgctgcg cagctgcggc tcgctcctgc ccgaactgag tcttgcagag
      481 aggacagaat ttgctcataa gatatgggac aaacttcagc agttaggcac cgtgtacgat
      541 gtcagtcatt ataatgcttt acttaaagta tatcttcaaa atgaataccg attctcacct
      601 actgacttcc tggcaaagat ggagggagca aacattcaac cgaaccgagt gacataccag
      661 aggctgatcg ctgcctattg tagtgttggg gacattgaag gcgccagcaa gatccttgga
      721 tttatgaaaa cgagggacct tccaatcaca gaggctgtgt tcagtgcgct cgtcacaggg
      781 cacgccagag ctggggatat ggagaatgca gagaatattc tcacagtgat gaaacaggct
      841 ggcattgagc ctgggccaga cacgtatctg gccttgttga acgcacatgc tgagaagggt
      901 gacattgacc atgttaagca gattctggag aaagtggaaa aatcggatca ttactttatg
      961 gaccgtgatt tcttgcaaat tattgttagc tttagtaaag ctggatatcc tcagtatgtc
     1021 tcagaaattt tggagaagat tacctatgag agaagatcta ttccagatgc aatgaacctc
     1081 attttgcttt tagtcactga gaagttagaa gacacggcgt tccaggtttt actggcatta
     1141 cccctggcca gggatgagac ctcaagtagt tttggcagtt tctttttgcg gcactgtgtg
     1201 actatggata cgcctgctga gaagctgata gactactgta agagactgag ggacgccaag
     1261 gtgcacagct cttcactgca gttcaccctg cactgtgctc ttcaagccaa taagactgct
     1321 ttggcaaaag cagtgatgga ggctctgagg gatgaagggt ttcctatccg aactcactat
     1381 ttctggccgt tgcttgttgg acatcagaaa acaaaaaatg ttcaaggaat aatagatatt
     1441 cttaaaatca tgaaggaaat gggagtggat cccgatcagg aaacatacat aaattatgtg
     1501 tttccctgct tcggtagtgt gcagtcggct cgagctgctc tgcaggaaaa taaatgtctg
     1561 cctaaaagta ctacattcgc tcaagccgaa gtgagaaatg aagcaataaa tgggaattta
     1621 cagaacattt tgtcattttt ggaatcgaat gcattgcctt tctcgtttaa ttctttgaga
     1681 ggcagcctaa ttctaggctt taggaggtcg atgaatatag atctttggag caagataaca
     1741 gaattgctgt acaaggatga ccgttattgc caaaaacctc caggaccaac ggaagctgtt
     1801 ggctattttc tttataactt gattgacagc atgagtgact cagaggtgca ggccaaggag
     1861 gagcgcttga gacaatactt ccatcagctt cgagaaatga atgttaaagt ttctgaaaac
     1921 atctacaaag gcatttgtaa tttgctggat aactaccatg ttcctgaatt gattaaggat
     1981 gttaaggttc tggttgacag agagaagata gattctcgaa aaacctccca gtttacctca
     2041 tctgatttgg agtcaaccct tgagaagctt aaagctgaag gccatcctgt aggagacccc
     2101 ctgaagcagc tcatcttgct gctctgttct gaggagaata tgcaaaaggc ccttgaagtg
     2161 aaagcaaaat acgagtcaga catggttatt ggaggctatg cagctttaat aaatttgtgc
     2221 tgtcgacatg ataatgcaga agatgcactg aacttgaaac aagaatttga ccgcttagat
     2281 ccttcagctg ttcttgacac tgccaagtat gtagccctgg taaaagtatt gggaaagcat
     2341 ggcagagtgc aagatgctat taacattcta aaggagatga aagagaagga tgttgttatc
     2401 aaagatgcag cagtcttgtc cttcttccac atcctgaatg gtgcagcttt aagaggtgaa
     2461 attgagacag taaaacagtt gcatgaagcc atcgtgactc ttgggttggc aaagccatcc
     2521 agcaacataa gcttcccatt ggtcactgtg cacctggaaa aggatgattt acctgctgct
     2581 cttgaagcca gcattgcctg ccatgaaaaa tataaagtat tacccaggat tcatgatgtc
     2641 ttatgtaagc taatagaaaa aggcgagact gacttaatcc agaaagcgat ggactttgtc
     2701 agccaagagc agggcgagat gtcgatgctc tacgacctct tctttgcttt cctgcagacg
     2761 ggaaactaca aagaggccaa gaagattatt gagactccag gcattagagc tcggcctaca
     2821 cgacttcagt ggttttgtga tagatgcatt gccaataatc aggttgaaac tcttgagaag
     2881 ttagtggagc tgaccgagaa gctgtttgaa tgtgacagag accagatgta ctacaactta
     2941 ctgaaactat acaaaataag cggtgactgg caaagagcgg atgctgtctg gaataaaatg
     3001 caagaagaga atcttatccc tcgagaacgg acactgcgac tgttagctgg gatcctgaaa
     3061 accagcaacc aggaggttcc ttttgacgtt cctgagttgt ggtttggaga tgacaggtct
     3121 tccctgagtt catcctcacc ctcagcagga gacaccgtga ctgagaagat gttgttgtct
     3181 gactgcagac tgaagaagag taaggatgca tataatatct tcctcaaagc cgaaaagcaa
     3241 gatgtcgtct tcagcagtga ggcttacagc accctggttg gcttgctgct gagcaaagat
     3301 gacttcacac gagccatgca tgtgaaagat ttcgctgaga cccacatcaa gggcttcaca
     3361 ctgaacggtg ctgccagcag cctcctcatc atcgcgcaag ttaggcggga ttatttgaaa
     3421 gtggctctag aaactctgaa ggcagccttg gatctggaac aggtgccttc tgagctggcc
     3481 gtgacccgcc ttatccaggc actggccttg cagggtgatg tgaaaagcat agagaccatt
     3541 cagaagatgg tgaaagggct cgacgcgatt gagctctcaa gaatggtctt catcaacaac
     3601 attgctctgg cccagatgaa gaataatgaa attgatgctg ccatagaaaa tatcgagcac
     3661 atgcttgcct cagagaatca gaccgtggaa caccagtact ttggcttgtc gtacttattc
     3721 aggaaagtga tagaggagca gatggagcca gcgctcgaaa agttaagcat catgtctgag
     3781 aggttggcca atcagtttgc actttacaaa cccgtcactg atctcttcct tcagcttgtg
     3841 gattcaggca aggtggatga ggccagagcc ctcttggaga gatgcggcgc cattgccgag
     3901 cagacctcaa ttctgtcggt gttctgtctc aggacgtctc agaaaccaaa aaaggccccg
     3961 gttctgaaga ccttgttaga gctgattccc gagttacgtg agaatgacag agtatactcc
     4021 tgcagcatga aaagctatgt cgcagacaaa gacgtggcct ccgctaaagc gctgtatgag
     4081 catttgacag caaagaacat gaagctggac gacctctttc tgaagcgcta cgcatctttg
     4141 ctcaaggatg tgggcgagcc ggtccccttc actgagcccc ctgaaagctt tggattttac
     4201 ataaagcaac taaaggaagc gagagaaaac ccctcatgaa agaagcagct gtgtgtgtct
     4261 gtgtgtgtct gtgtgtctgt gtgtctgtgt ctgtgtgcac gcgcctgtgt ctcaatgtta
     4321 tttctaaaat gtacttagga aaaataaaca actgaagatt a
//
