LOCUS       NM_001017443            1540 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Rattus norvegicus Lrp2 binding protein (Lrp2bp), mRNA.
ACCESSION   NM_001017443 XM_224864
VERSION     NM_001017443.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1540)
  AUTHORS   Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
            Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
            Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
            Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
            Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
            Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
            Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
            Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
            Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
            McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
            Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
            Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
            Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
            Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
            Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
            Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
            Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
            Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
  CONSRTM   Mammalian Gene Collection Program Team
  TITLE     Generation and initial analysis of more than 15,000 full-length
            human and mouse cDNA sequences
  JOURNAL   Proc Natl Acad Sci U S A 99 (26), 16899-16903 (2002)
   PUBMED   12477932
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC092575.1.
            
            On Apr 29, 2005 this sequence version replaced XM_224864.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC092575.1, BC079231.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1540
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q11"
     gene            1..1540
                     /gene="Lrp2bp"
                     /gene_synonym="RGD1305896"
                     /note="Lrp2 binding protein"
                     /db_xref="GeneID:290753"
                     /db_xref="RGD:1305896"
     exon            1..166
                     /gene="Lrp2bp"
                     /gene_synonym="RGD1305896"
                     /inference="alignment:Splign:2.1.0"
     exon            167..287
                     /gene="Lrp2bp"
                     /gene_synonym="RGD1305896"
                     /inference="alignment:Splign:2.1.0"
     CDS             188..1228
                     /gene="Lrp2bp"
                     /gene_synonym="RGD1305896"
                     /note="low density lipoprotein receptor-related protein 2
                     binding protein; megalin-binding protein"
                     /codon_start=1
                     /product="LRP2-binding protein"
                     /protein_id="NP_001017443.1"
                     /db_xref="GeneID:290753"
                     /db_xref="RGD:1305896"
                     /translation="MKLTSEKLPKNPFSLSQYAAKQQTFFQWKKEKPDYYRHANLVDT
                     ALQFLKERIRKGDAMAYFLRGQLYFEEGWYEEALAQFEEIQEKDHQAIYQLGVMYYDG
                     LGTVADAEKGVGYMKKILDSSCPQTMHLKFAAAYNLGRAYFEGKGVKRSDEEAERLWL
                     YAADNGNPKASVKAQSILGLFYSMKEPKDLEKAFFWHSEACGNGNLESQGALGLMYLY
                     GQGIRQDTDAALHCLREAAERGNVYAQGILVEYYYKMKFFTKCVSFSKRIADYDEVHD
                     IPMIAHVTDCLPEFISKGMAMASFYYARCLQLGLGITKDEASAKHYYSKACRLNPTLA
                     DELHSLLIHQRI"
     exon            288..400
                     /gene="Lrp2bp"
                     /gene_synonym="RGD1305896"
                     /inference="alignment:Splign:2.1.0"
     exon            401..514
                     /gene="Lrp2bp"
                     /gene_synonym="RGD1305896"
                     /inference="alignment:Splign:2.1.0"
     exon            515..657
                     /gene="Lrp2bp"
                     /gene_synonym="RGD1305896"
                     /inference="alignment:Splign:2.1.0"
     exon            658..763
                     /gene="Lrp2bp"
                     /gene_synonym="RGD1305896"
                     /inference="alignment:Splign:2.1.0"
     exon            764..987
                     /gene="Lrp2bp"
                     /gene_synonym="RGD1305896"
                     /inference="alignment:Splign:2.1.0"
     exon            988..1162
                     /gene="Lrp2bp"
                     /gene_synonym="RGD1305896"
                     /inference="alignment:Splign:2.1.0"
     exon            1163..1510
                     /gene="Lrp2bp"
                     /gene_synonym="RGD1305896"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagcttaggc caacctggac tccttcaacc caaatgaggt ggtccctaca ctttatatga
       61 aggctctgat ttaccataca gtggtgatcc atccggtaac atggcaatcc catacagact
      121 ggaagagaaa actgagcaac agagctaaaa tacagtgtgt tcccaggatc catattgtgg
      181 aaacgggatg aaactgacca gtgagaagtt gcccaaaaac cctttctcgc tatctcagta
      241 cgctgctaag caacaaacgt tcttccagtg gaagaaggaa aagcctgatt attaccgcca
      301 tgctaatttg gtggatacag cactgcagtt cctgaaagaa aggataagaa aaggggatgc
      361 tatggcatat tttctaagag gccaactcta ttttgaagag ggctggtacg aagaagcctt
      421 agcacaattt gaagaaatcc aggagaaaga ccatcaggca atttatcagc taggagtgat
      481 gtattatgat gggttgggga ctgtcgcaga tgctgaaaaa ggagtgggct atatgaagaa
      541 aatccttgat tcttcatgcc cccagacaat gcacttgaaa tttgctgctg cttacaacct
      601 cggaagagct tattttgaag gaaaaggcgt gaagcgatcc gacgaggaag cggagagact
      661 gtggctttac gctgctgaca atggaaaccc aaaagctagt gtgaaggcac aaagtattct
      721 aggattgttt tattcaatga aagagcccaa agacttagaa aaggcatttt tctggcattc
      781 ggaagcttgt ggcaatggaa atctggagtc ccagggtgca cttggtctca tgtaccttta
      841 cggacaggga attcgccaag acactgacgc cgccctgcac tgcttacggg aagcagctga
      901 acgagggaat gtctatgccc aggggattct tgtggagtac tactacaaga tgaagttctt
      961 taccaagtgt gtttcgtttt ccaaaaggat agcagactat gatgaggttc acgacatccc
     1021 catgatagcc catgtcacag actgtctccc agagtttatc agcaaaggca tggccatggc
     1081 gtctttctac tatgcgcggt gtctccagct tggcttgggc attacaaaag acgaagcatc
     1141 tgccaagcac tattattcta aagcttgccg tctgaaccct acactggcag atgaacttca
     1201 ctccttactt attcaccaga gaatttagac cacaaagcat ttcaacaaag accaccaatt
     1261 ctaactggaa acaatgtgtg tgtgtttaca gcggctacat ctgtatcctg ctgtattatc
     1321 cagggtattt cacagaaatt ttagttttgt tattatattt gtattctgta atttttacaa
     1381 actaaaattt agacaccaac caaattgctg ggaagagatt cagagactat agagtggcct
     1441 gaactgtact gagtttgaaa acatgccaag agcaaatacc tctttgcctt attaaatgca
     1501 gtgtctgaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
