LOCUS       NM_001134883            4040 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus LDL receptor related protein 12 (Lrp12), mRNA.
ACCESSION   NM_001134883 XM_235261
VERSION     NM_001134883.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4040)
  AUTHORS   Grote,A., Robens,B.K., Blumcke,I., Becker,A.J., Schoch,S. and
            Gembe,E.
  TITLE     LRP12 silencing during brain development results in cortical
            dyslamination and seizure sensitization
  JOURNAL   Neurobiol Dis 86, 170-176 (2016)
   PUBMED   26639854
REFERENCE   2  (bases 1 to 4040)
  AUTHORS   Battle,M.A., Maher,V.M. and McCormick,J.J.
  TITLE     ST7 is a novel low-density lipoprotein receptor-related protein
            (LRP) with a cytoplasmic tail that interacts with proteins related
            to signal transduction pathways
  JOURNAL   Biochemistry 42 (24), 7270-7282 (2003)
   PUBMED   12809483
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Sep 11, 2008 this sequence version replaced XM_235261.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360172.556322.1,
                                           SRR26643288.30617.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-163               JAXUCZ010000007.1  72896894-72897056   c
            164-220             JAXUCZ010000007.1  72862479-72862535   c
            221-356             JAXUCZ010000007.1  72842704-72842839   c
            357-559             JAXUCZ010000007.1  72835466-72835668   c
            560-1664            JAXUCZ010000007.1  72833358-72834462   c
            1665-1797           JAXUCZ010000007.1  72831720-72831852   c
            1798-4040           JAXUCZ010000007.1  72825979-72828221   c
FEATURES             Location/Qualifiers
     source          1..4040
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q31"
     gene            1..4040
                     /gene="Lrp12"
                     /note="LDL receptor related protein 12"
                     /db_xref="GeneID:314941"
                     /db_xref="RGD:1304943"
     exon            1..163
                     /gene="Lrp12"
                     /inference="alignment:Splign:2.1.0"
     CDS             85..2661
                     /gene="Lrp12"
                     /note="low density lipoprotein-related protein 12; low
                     density lipoprotein receptor-related protein 12"
                     /codon_start=1
                     /product="low-density lipoprotein receptor-related protein
                     12 precursor"
                     /protein_id="NP_001128355.1"
                     /db_xref="GeneID:314941"
                     /db_xref="RGD:1304943"
                     /translation="MARRWSTKESPRRGSAWLLLFLAGVYGNGALAELSENVHISGVS
                     TACGETPEQIRGPTGIITSPGWPSDYPAKINCSWLIRANPGEIITISFQDFDIQGSRR
                     CTLDWLTIETYKNIESYRACGSTIPPPYISSQDHVWIRFHSDDSVSRKGFRLAYFSGK
                     SEEPHCACDQFRCGNGKCIPEAWKCNSMDECGDSSDEEVCVQDAHPPTTTAFQPCAYN
                     QFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDEIDCDMPTCGQWLKYFYGTFSSPNYP
                     DFYPPGSNCTWLIDTGDHRKVILRFTDFKLDGTGYGDYVKIYDGLEENPRKLLRVLTA
                     FDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQ
                     QRCDGYWHCPNGRDEINCTMCQKEEFPCSRNGVCYPRSDRCNYQNHCPNGSDEKNCFF
                     CQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEESCPVIVPTRVITAAVIGSLVCGLLL
                     VIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPV
                     CSPNQASVLENLRLAVRSQLGFPSIRLPMTGRSRNIWNRIFNFARSRHSGSLALVSGD
                     GDEVVPSQSSSRETERSHPHRSLFSAESDDTDTENERRDTAGASGGVAAPLPQKVPPT
                     TAVEATVGTGGNSSAQSTRGGHADGREVSSVEAPSVSPARHQLTSALSRMTQGLRWVR
                     FTLGRSSSTNQNRSPLRQLDTGVSGREDDDDVEMLIPVSDGASDIDANECSRPLLDLA
                     SDQVQGFRQPHSSGNPGARTSNRDGPCERCGIVHTAQIPDTCLEAAVKTEACDDEALL
                     LC"
     exon            164..220
                     /gene="Lrp12"
                     /inference="alignment:Splign:2.1.0"
     exon            221..356
                     /gene="Lrp12"
                     /inference="alignment:Splign:2.1.0"
     exon            357..559
                     /gene="Lrp12"
                     /inference="alignment:Splign:2.1.0"
     exon            560..1664
                     /gene="Lrp12"
                     /inference="alignment:Splign:2.1.0"
     exon            1665..1797
                     /gene="Lrp12"
                     /inference="alignment:Splign:2.1.0"
     exon            1798..4040
                     /gene="Lrp12"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggggctcgg cggcggcggc gtctggcccc agctcctcct cctcctcctc ctccatctcc
       61 tcgctccctc catctgccgt gggtatggcc cgtcgctgga gcacaaagga gtctccgcgg
      121 cgggggtcgg cgtggctctt gcttttcctc gctggggtgt acggaaatgg tgctcttgca
      181 gaactttccg aaaatgtgca tatttcagga gtgtcaactg cttgtggtga gactccagaa
      241 caaattcgag ggccgactgg aataatcacg agcccaggct ggccttcaga ctaccccgcc
      301 aagatcaact gtagctggct catacgggca aacccagggg agatcattac tataagtttt
      361 caggattttg atatccaggg gtccaggaga tgcactttgg actggctgac aatagaaaca
      421 tacaagaata ttgaaagtta cagagcttgt gggtccacaa ttccgcctcc gtatatctct
      481 tcacaagacc acgtttggat ccggttccac tcagatgaca gtgtgtccag gaaaggcttc
      541 aggttggcgt atttttcagg gaaatcggag gagccacact gtgcctgtga ccagttccgc
      601 tgtggcaatg ggaagtgcat tcccgaagcc tggaagtgca acagcatgga cgagtgtgga
      661 gatagctctg acgaggaggt ctgtgtccaa gacgctcacc ccccaacaac gaccgcattc
      721 cagccctgcg cctacaacca gttccagtgt ctgtcccgct tcaccaaagt ttacacttgc
      781 ctccctgagt ccttgaagtg tgatggcaac attgactgcc tggacctggg agatgagatc
      841 gactgtgata tgccgacatg cgggcagtgg ttaaaatact tctatggaac ttttagttct
      901 cccaactacc ccgactttta ccctcctgga agtaactgca cctggctgat agacactggc
      961 gatcatcgga aagtcatctt acggtttact gactttaaac tcgatggtac cggatatggt
     1021 gattatgtca aaatatatga cggactggag gagaatcctc gcaagctttt gcgagtgcta
     1081 actgcttttg attctcacgc tcccctgaca gtcgtttctt cctccggaca gataagagtg
     1141 catttttgtg ctgacaaagt gaacgctgcc agaggcttca atgctactta ccaagtcgac
     1201 ggcttctgtt tgccgtggga aataccctgt gggggtaact gggggtgtta cacagagcag
     1261 cagcgctgtg atggctactg gcattgccca aacggaaggg atgagatcaa ctgtaccatg
     1321 tgccaaaagg aagaatttcc atgttctcgg aatggtgtct gctaccctcg ttctgatcgc
     1381 tgcaactacc aaaatcattg tccaaacggc tctgatgaaa aaaactgctt cttttgccag
     1441 ccagggaatt tccactgcaa gaacaaccgc tgtgtgttcg aaagctgggt gtgtgactca
     1501 caggatgact gtggggacgg cagcgatgag gagagctgcc cggtcattgt gcccacccga
     1561 gtcataacag cagccgtcat cgggagcctg gtctgtggcc tgctgcttgt cattgctctg
     1621 ggctgcactt gcaagctcta ttctctaagg atgtttgagc ggagatcatt tgagacccag
     1681 ttgtcacgag tggaagcaga gctgctgcga agagaggctc ctccctcata tggacagctg
     1741 atcgcgcagg gcctaatccc tccggtggaa gactttcctg tctgttcacc taatcaggct
     1801 tcagttttag aaaacctgcg gctagctgtc cgatctcagc tgggatttcc ttctatcaga
     1861 cttcctatga caggcagatc tcgaaatatt tggaatcgta tttttaactt tgcaagatct
     1921 cgtcattcag ggtcgctggc tttggtctca ggagatggag atgaggttgt ccccagccag
     1981 agcagcagca gagagactga aaggagtcac cctcacagaa gcttgttttc cgcggagtct
     2041 gatgacacag acacagaaaa tgagagaagg gatacggcgg gagcatctgg tggggttgca
     2101 gctcctttgc cccagaaagt ccctcccaca actgcggtag aggccacagt ggggacaggt
     2161 gggaactcct cagctcagag cacccgaggt ggccacgcag atggaaggga agtgtcaagt
     2221 gtggaagccc caagtgtgag cccagcacgt caccagctca caagtgcttt aagtcgaatg
     2281 actcagggcc tgcgctgggt acgctttact ttaggtcgat caagctccac aaaccagaac
     2341 cggagtcctt tgagacagct tgacaccggg gtgagtggaa gagaagacga cgatgacgtt
     2401 gaaatgctaa ttcccgtttc tgatggagct tcggacattg atgccaatga atgctccaga
     2461 cctcttcttg atcttgcctc agaccaagta caagggttta gacagccaca cagttcagga
     2521 aaccctggag cgagaacaag taaccgggac ggcccctgcg agcgctgtgg cattgtgcac
     2581 acggcccaga taccagacac ttgcttagaa gcggcagtga aaactgaagc gtgtgatgac
     2641 gaggctttgc tgctgtgtta ggacagaatg gacagacaga ctgtgtgcaa gctggagcaa
     2701 tagccaccca ttgttttgta actttacaat taaactagtt ttagtttaaa agatgcaggg
     2761 tgatttctta ttatacgtta gcctgcatgg ttaaatttaa caatgtctaa ctctaggagc
     2821 tagagtttac tgttttagca gctacaaatg cattatgtat ccatgttctt ccatttcctt
     2881 atacttggtt ttgtttttgt ttttttaatc ctggtacttc agtttaatag tagaaatatg
     2941 gctgctttaa ttcatgtaac tgtcgtttta tctatcttat gttaaaaggt ttgcttgtac
     3001 aaaaaggtac cttcttttaa ttgaaccttt tttgctcttt gtcatcatgt agtttattat
     3061 actggatgct aaggttgttg atgtacaaaa gagaaaacag tatagccccc tctttgtttt
     3121 cctaacattg tctgctaata gatttcatca tacggacctg tcaagggaaa agaaactcct
     3181 tttacgttca acaggcagtg atgtaaaagt tacgtagagt tagagcaatt gctgtcagga
     3241 agcaaaactt ttatagattt ttctaatgct gactttaata ctctggtatg gttcagacca
     3301 aatggtgaaa tcgcagtgca tttctgtttt catctcgatt taggggcaga agtaagcgga
     3361 tgaagatact ctactatgca taacactttg aactttataa aatacgtaca gaattgtgca
     3421 cactcagctc taacacgggg gaatgtcggc ctgagtcgga ccctagggat ccgcactacc
     3481 gtcctgccga ggtctcaggt gagctgagca ggcactgtca cggcaggtct gtcgtcgctg
     3541 ccacagtgac tctttctcca tagctttggg gtgggggcca tttttattac aacttgaaat
     3601 tgatttgctg gtttcatatt tatttgttgt atttaaaaac tgcattattg taagagtgat
     3661 tttttccagg atattttatt cttgtgggag ggggtcaatg ctataatctt gaagaaaagc
     3721 aaattaaatt gttcagactg tccccctctt taagtagagt gaattacaac ccccatttat
     3781 tgttctttaa ttgttaattc ttgtttattt attcttagct gtctgtttta gcagcttaat
     3841 gattgggtat gaaaatgtgt ctgtgtgatt attgctattt attatatttt gaatactttg
     3901 ctgaatgtca ttttaaagca tgtttgaggt cttgtgtatc tgtcctgtta tgctgtcagg
     3961 aagacctgac taaaatgttt taatatgtat aaaaaaatta aaataatttt ttattgcctt
     4021 gaggtacttt ttaaatcaaa
//
