LOCUS       XP_216905               1116 aa            linear   ROD 22-FEB-2024
DEFINITION  leucine-rich repeats and immunoglobulin-like domains protein 3
            [Rattus norvegicus].
ACCESSION   XP_216905
VERSION     XP_216905.5
DBLINK      BioProject: PRJNA1074393
DBSOURCE    REFSEQ: accession XM_216905.11
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_086025) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Jul 30, 2024 this sequence was replaced by
            NP_001419387.1.
            
            On Apr 2, 2010 this sequence version replaced XP_216905.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_036323735.1-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/09/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1116
                     /organism="Rattus norvegicus"
                     /strain="BN/NHsdMcwi"
                     /bio_material="RGD 61498"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /sex="male"
                     /tissue_type="kidney, spleen, liver"
                     /geo_loc_name="USA: Wisconsin, Milwaukee"
                     /lat_lon="43.05 N 88.04 W"
                     /collected_by="Rebecca Schilling, Melinda Dwinell"
     Protein         1..1116
                     /product="leucine-rich repeats and immunoglobulin-like
                     domains protein 3"
                     /calculated_mol_wt=122461
     Region          76..99
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275378"
     Region          77..421
                     /region_name="LRR"
                     /note="Leucine-rich repeat (LRR) protein [Transcription];
                     COG4886"
                     /db_xref="CDD:443914"
     Region          100..115
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275378"
     Region          147..168
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          169..192
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          194..216
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          217..240
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          241..264
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          265..288
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          289..312
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          313..336
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          337..360
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          361..385
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          388..411
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          412..435
                     /region_name="leucine-rich repeat"
                     /note="leucine-rich repeat [structural motif]"
                     /db_xref="CDD:275380"
     Region          416..>494
                     /region_name="PCC"
                     /note="polycystin cation channel protein; TIGR00864"
                     /db_xref="CDD:188093"
     Region          498..585
                     /region_name="Ig_3"
                     /note="Immunoglobulin domain; pfam13927"
                     /db_xref="CDD:464046"
     Region          604..694
                     /region_name="IgI_LRIG1-like"
                     /note="Immunoglobulin (Ig)-like ectodomain of the LRIG1
                     (Leucine-rich Repeats And Immunoglobulin-like Domains
                     Protein 1) and similar proteins; member of the I-set of
                     IgSF domains; cd05763"
                     /db_xref="CDD:409420"
     Region          604..607
                     /region_name="Ig strand A"
                     /note="Ig strand A [structural motif]"
                     /db_xref="CDD:409420"
     Region          611..615
                     /region_name="Ig strand A'"
                     /note="Ig strand A' [structural motif]"
                     /db_xref="CDD:409420"
     Region          618..627
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409420"
     Region          633..638
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409420"
     Region          641..643
                     /region_name="Ig strand C'"
                     /note="Ig strand C' [structural motif]"
                     /db_xref="CDD:409420"
     Region          651..655
                     /region_name="Ig strand D"
                     /note="Ig strand D [structural motif]"
                     /db_xref="CDD:409420"
     Region          659..666
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409420"
     Region          672..680
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409420"
     Region          683..694
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409420"
     Region          697..784
                     /region_name="I-set"
                     /note="Immunoglobulin I-set domain; pfam07679"
                     /db_xref="CDD:400151"
     Region          714..718
                     /region_name="Ig strand B"
                     /note="Ig strand B [structural motif]"
                     /db_xref="CDD:409353"
     Region          727..731
                     /region_name="Ig strand C"
                     /note="Ig strand C [structural motif]"
                     /db_xref="CDD:409353"
     Region          750..754
                     /region_name="Ig strand E"
                     /note="Ig strand E [structural motif]"
                     /db_xref="CDD:409353"
     Region          764..769
                     /region_name="Ig strand F"
                     /note="Ig strand F [structural motif]"
                     /db_xref="CDD:409353"
     Region          777..780
                     /region_name="Ig strand G"
                     /note="Ig strand G [structural motif]"
                     /db_xref="CDD:409353"
     CDS             1..1116
                     /gene="Lrig3"
                     /coded_by="XM_216905.11:299..3649"
                     /db_xref="GeneID:299830"
                     /db_xref="RGD:1561255"
ORIGIN      
        1 mgapglraaa aalglllcag lgragpagsg ghgapgqlsd eatrrpcpaa chclgdlldc
       61 srrrlirlpd plpawvtrld lshnrlsfiq asslshlqsl qevklnnnel etipnlgpvs
      121 anirqlslag naidkilpeq leafqsletl dlsnnnisel rtafpplqlk ylyinsnrvt
      181 smepgyfdnl gstllvlkln rnrisaippk mfklpqlqhl elnrnkiknv dgltfqglga
      241 lkslkmqrng vtklmdgafw glsnmeilql dhnnlteitk gwlygllmlr elhlsqnain
      301 rispdawefc qklseldltf nhlsrlddss flglsllnal hvgnnkvsyi adcafrglss
      361 lktldlrnne iswtiedmng afsgldklrq lilqgnrirs itkkafagld tlehldlsgn
      421 aimslqnnaf sqmkklqqlh lntssllcdc qlkwlpqwva ennfqsfvna scahpqplkg
      481 rsiftvspdg fvcddfpkpq itvqpetqsa ikgsdvsftc saasssdspm tfawkkdnea
      541 lqdaemenya hlraqggelm eyttilrlrn vefasegryq cvisnhfgss ysvkarltin
      601 mlpsftktpm dltiragama rlecaavghp apqiawqkdg gidfpaarer rmhvmpeddv
      661 ffivdvkied igvysctaqn sagsvsanat ltvletpsfl rplldrtvtk getavlqcia
      721 ggsppprlnw tkddsplvvt erhffaagnq lliivdsdvs dagkytcems ntlgtergnv
      781 rlsviptptc dsphmtapsl dgdgwatvgv viiavvccvv gtslvwvvii yhtrrrnedc
      841 sitntdetnl padipsylss qgtladrqdg yissengshh qfvtssgggf flpqhdsagt
      901 chfddssead veaapdpflc pfvsssgpvy lkgnlygpdp fevylpgcss dprialmdhc
      961 essytkkdcf scahpseepc erslksipwp hsrklmnsaf sqnegpavqt lrlnksvdfs
     1021 tspepgsats snsfmgtfgk plrrpqldal ssfaqppdcq prpchgksls ppeldsesee
     1081 dekertdfre enhrctyqqi lhsyrtpdrq pcdsdt
//
