LOCUS       NM_001013864            2240 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus LIM domain containing preferred translocation
            partner in lipoma (Lpp), mRNA.
ACCESSION   NM_001013864 XM_221337
VERSION     NM_001013864.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2240)
  AUTHORS   Hooper,C.L., Paudyal,A., Dash,P.R. and Boateng,S.Y.
  TITLE     Modulation of stretch-induced myocyte remodeling and gene
            expression by nitric oxide: a novel role for lipoma preferred
            partner in myofibrillogenesis
  JOURNAL   Am J Physiol Heart Circ Physiol 304 (10), H1302-H1313 (2013)
   PUBMED   23504181
  REMARK    GeneRIF: LPP knockdown by small intefering RNA led to formation of
            alpha-actinin aggregates and Z bodies showing that
            myofibrillogenesis was impaired
REFERENCE   2  (bases 1 to 2240)
  AUTHORS   Kuo,J.C., Han,X., Hsiao,C.T., Yates,J.R. 3rd and Waterman,C.M.
  TITLE     Analysis of the myosin-II-responsive focal adhesion proteome
            reveals a role for beta-Pix in negative regulation of focal
            adhesion maturation
  JOURNAL   Nat Cell Biol 13 (4), 383-393 (2011)
   PUBMED   21423176
REFERENCE   3  (bases 1 to 2240)
  AUTHORS   Hoffert,J.D., Pisitkun,T., Wang,G., Shen,R.F. and Knepper,M.A.
  TITLE     Quantitative phosphoproteomics of vasopressin-sensitive renal
            cells: regulation of aquaporin-2 phosphorylation at two sites
  JOURNAL   Proc Natl Acad Sci U S A 103 (18), 7159-7164 (2006)
   PUBMED   16641100
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083627.1.
            
            On Apr 20, 2005 this sequence version replaced XM_221337.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083627.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2240
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q23"
     gene            1..2240
                     /gene="Lpp"
                     /note="LIM domain containing preferred translocation
                     partner in lipoma"
                     /db_xref="GeneID:288010"
                     /db_xref="RGD:1310535"
     exon            1..36
                     /gene="Lpp"
                     /inference="alignment:Splign:2.1.0"
     exon            37..97
                     /gene="Lpp"
                     /inference="alignment:Splign:2.1.0"
     exon            98..299
                     /gene="Lpp"
                     /inference="alignment:Splign:2.1.0"
     CDS             107..2005
                     /gene="Lpp"
                     /note="Lipoma-preferred-partner"
                     /codon_start=1
                     /product="lipoma-preferred partner homolog"
                     /protein_id="NP_001013886.1"
                     /db_xref="GeneID:288010"
                     /db_xref="RGD:1310535"
                     /translation="MSHPSWLPPRSTGEPLGHVPARMETTHSFGTPSISVSTQQPPKK
                     FAPVVAPKPKYNPYKQPGGEGDFLPPPPPPLEDPGTIPSGSGHFPPPPPLDEGAFIVQ
                     RGNPGGKTLEERRSSLDAEIDSLTSILADLECSSPYKPRAPPGSSSSIASPPVSTPVT
                     GHKRMVIPQQPPLTATKKSATKPQAIPIPVTPIGTLKPQPQPVPASYSTASTSSRPAF
                     NVQVKSAQPSTHYMTGSSSGQMYGPGSRSYNTQQVPLSAQCPPPTTCAGTDYAYIPPS
                     GQQAESGFGYTSNQGRYFEPFFAACPSYGGRNEADPAYGQQVQPNTWKREPGYAAPGA
                     GNQNQPGMYSVSGPKKTYITDPVSAPCAPPVQPKERLVKNQKVLQNVVDDRVHGLRKS
                     GFPAPMGPPSVPPSFRPEDELEHLTKKMLYDMENPPADDYFGRCARCGENVVGEGTGC
                     TAMDQVFHVDCFTCMVCDIKLRGQPFYAVEKKAYCEPCYINTLEQCSVCSKPIMERIL
                     RATGKAYHPHCFTCVMCHRSLDGIPFTVDACGLIHCIEDFHKKFAPRCSVCKEPIMPA
                     PGQEETVRIVALDRDFHVHCYRCEDCGGLLSEGDNQGCYPLDGHILCKSCNSARIRVL
                     TAKASTDL"
     exon            300..412
                     /gene="Lpp"
                     /inference="alignment:Splign:2.1.0"
     exon            413..538
                     /gene="Lpp"
                     /inference="alignment:Splign:2.1.0"
     exon            539..1210
                     /gene="Lpp"
                     /inference="alignment:Splign:2.1.0"
     exon            1211..1279
                     /gene="Lpp"
                     /inference="alignment:Splign:2.1.0"
     exon            1280..1406
                     /gene="Lpp"
                     /inference="alignment:Splign:2.1.0"
     exon            1407..1576
                     /gene="Lpp"
                     /inference="alignment:Splign:2.1.0"
     exon            1577..1755
                     /gene="Lpp"
                     /inference="alignment:Splign:2.1.0"
     exon            1756..1876
                     /gene="Lpp"
                     /inference="alignment:Splign:2.1.0"
     exon            1877..2214
                     /gene="Lpp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agctcattgc caagagtgga agttcgctaa gatcagaacc tagcaaatcg tctggctgag
       61 cccgtgacca ttgttccaga agccaaacac tgctgagatt tcaacaatgt ctcacccatc
      121 ttggctgcca cccagaagca ctggtgagcc tcttggccat gttcctgcgc ggatggagac
      181 cacccattct tttgggaccc ccagtatttc agtgtcaaca caacagccac ccaagaagtt
      241 tgctccagtg gttgctccaa aacccaagta taacccgtac aagcagcccg gaggagaggg
      301 tgattttctc ccacccccac ctccgccact agaggatcct ggtaccatcc catctgggtc
      361 cgggcacttc cctcctcctc caccattgga tgaaggtgct ttcatagtgc agcggggaaa
      421 tcctggaggc aagaccctgg aggaacggcg ttccagcttg gatgcagaga tcgactcctt
      481 gacgagcatc ttggctgatt tggagtgcag ctcgccctac aagcctcggg ccccaccggg
      541 ctctagtagt tccattgcgt ctcctccagt ttctactcct gtcacgggac ataagagaat
      601 ggtcattcca cagcagccac ctctgacagc aaccaagaag tccgcaacga agccacaggc
      661 tatacccatt ccagtgactc caattggaac actcaaaccg cagcctcagc cagttccagc
      721 ctcgtacagc accgcatcca catcttcaag gcccgccttc aatgtgcaag tgaagtccgc
      781 tcagcccagc acacattaca tgactggttc atcctctgga caaatgtatg gtccagggtc
      841 tcgcagctat aacacccaac aggttcctct gtcagcacag tgtcctcctc cgacaacgtg
      901 tgctggcacc gactatgcat acattccacc atcgggacaa caggctgagt ctggatttgg
      961 gtacacctcc aaccaaggac gctattttga gccttttttt gcagcgtgcc ctagctatgg
     1021 gggcagaaat gaagccgatc ctgcttatgg acaacaggtt caaccgaata cctggaagcg
     1081 ggaacctggg tatgctgctc ctggagccgg aaatcagaac cagcctggca tgtattcagt
     1141 cagtggtccc aagaagacct atatcacaga ccctgtttca gccccctgtg caccaccagt
     1201 gcagccaaag gagagactcg tgaagaacca gaaagtccta cagaatgttg ttgatgatcg
     1261 tgttcatgga ttgaggaaga gtggattccc tgcacctatg ggacctcctt cagttcctcc
     1321 atctttccgc ccagaagatg agctcgaaca cctgaccaag aagatgctgt atgacatgga
     1381 aaatccacct gctgatgatt actttggccg ctgtgcccgc tgtggggaaa acgtcgttgg
     1441 agaagggacg ggatgcaccg ccatggacca ggtcttccac gtggattgct tcacctgcat
     1501 ggtctgcgac atcaagctcc gaggacagcc tttctatgcc gtggagaaga aggcgtactg
     1561 cgagccctgc tacatcaata cgctggagca gtgcagtgtg tgttctaagc caatcatgga
     1621 gcggatcctc cgtgccaccg ggaaggcata ccacccccac tgcttcacct gcgtgatgtg
     1681 ccaccgcagc ctggatggca tcccgtttac cgtagacgca tgcggtctca ttcactgcat
     1741 tgaggacttc cacaagaaat ttgccccgcg ctgttctgtg tgcaaggaac ctatcatgcc
     1801 agccccaggc caggaggaga ccgtccgcat tgtggctctg gaccgtgatt tccatgtgca
     1861 ctgctaccgc tgtgaggact gtggtggtct tctatccgaa ggagacaacc aaggctgcta
     1921 ccccttggat gggcacatcc tctgtaagag ctgcaactcg gcccgcatca gggtcttgac
     1981 ggccaaggcg agcactgacc tgtagagtca gtcggtagcc agctcagctg ctgtgtgcct
     2041 gcctccaaga agaacgcaac acaaggaaaa gataagagaa gaaatagaaa aatagaggca
     2101 aagctcaacc tctgggatag tctctgttct tcatctgctg ttaacctttt ctgtagaagc
     2161 acatagatga tacgatttgt ctaagttctt accaaataca catttcacat ttaaaaaaaa
     2221 aaaaaaaaaa aaaaaaaaaa
//
