LOCUS       NM_001107592            3789 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus lysyl oxidase-like 4 (Loxl4), mRNA.
ACCESSION   NM_001107592 XM_001055686 XM_239059
VERSION     NM_001107592.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3789)
  AUTHORS   Ghai,R., Bugarcic,A., Liu,H., Norwood,S.J., Skeldal,S.,
            Coulson,E.J., Li,S.S., Teasdale,R.D. and Collins,B.M.
  TITLE     Structural basis for endosomal trafficking of diverse transmembrane
            cargos by PX-FERM proteins
  JOURNAL   Proc Natl Acad Sci U S A 110 (8), E643-E652 (2013)
   PUBMED   23382219
REFERENCE   2  (bases 1 to 3789)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   3  (bases 1 to 3789)
  AUTHORS   Ito,H., Akiyama,H., Iguchi,H., Iyama,K., Miyamoto,M., Ohsawa,K. and
            Nakamura,T.
  TITLE     Molecular cloning and biological activity of a novel lysyl
            oxidase-related gene expressed in cartilage
  JOURNAL   J Biol Chem 276 (26), 24023-24029 (2001)
   PUBMED   11292829
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473986.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_239059.4, XM_001055686.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN16676787
                              [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3789
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..3789
                     /gene="Loxl4"
                     /note="lysyl oxidase-like 4"
                     /db_xref="GeneID:309380"
                     /db_xref="RGD:1308588"
     exon            1..90
                     /gene="Loxl4"
                     /inference="alignment:Splign:2.1.0"
     exon            91..386
                     /gene="Loxl4"
                     /inference="alignment:Splign:2.1.0"
     CDS             107..2383
                     /gene="Loxl4"
                     /EC_number="1.4.3.13"
                     /note="lysyl oxidase homolog 4"
                     /codon_start=1
                     /product="lysyl oxidase homolog 4 precursor"
                     /protein_id="NP_001101062.1"
                     /db_xref="GeneID:309380"
                     /db_xref="RGD:1308588"
                     /translation="MMWPPPPTFSVFLLLLLSQVPSSRPQSPGTKKLRLVGPANRPEE
                     GRLEVLHQGQWGTVCDDDFALQEATVACRQLGFESALTWAHSAKFGQGEGPIWLDNVR
                     CLGTEDTLDQCGSNGWGVSDCRHSEDVGVVCHPRRQQGYHSEKVSNALGPQGRRLEEV
                     RLKPILASAKRHSPVTEGAVEVRYEGHWRQVCDQGWTMNNSRVVCGMLGFPSQAPVNS
                     HYYRKVWNLKMKDPKSRLNGLTKKNSFWIHRVDCLGTEPHLAKCQVQVAPGRGKLRPA
                     CPGGMHAVVNCVAGPHFQRQKPKPKRKESGAEQELKVRLRSGAQVGEGRVEVLMNRQW
                     GTVCDHRWNLISASVVCRQLGFGSAREALFGAQLGQGLGPIHLSEVRCRGYEQTIGDC
                     LALEGSQNGCQHANDAAVRCNIPDMGFQNKVRLAGGRNSEEGVVEVQVEVNGVPRWGT
                     VCSDHWGLTEAMVTCRQLGLGFANFAIKDTWYWQGTPEAKEVVMSGVRCSGTEMALQQ
                     CQRHGPVHCSHGSGRFSAGVACMNSAPDLVMNAQLVQETAYLEDRPLSMLYCAHEENC
                     LSKSADHMDWPYGHRRLLRFSSQIYNLGRADFRPKAGRHSWIWHQCHRHYHSIEVFTH
                     YDLLTLNGSKVAEGHKASFCLEDTNCPSGVQRRYACANFGEQGVAVGCWDTYRHDIDC
                     QWVDITDVSPGDYIFQVVVNPTNDVAESDFSNNMIRCRCKYDGQRVWLHNCHTGDPYR
                     PNAELSLEQEQRLRNNLI"
     exon            387..565
                     /gene="Loxl4"
                     /inference="alignment:Splign:2.1.0"
     exon            566..771
                     /gene="Loxl4"
                     /inference="alignment:Splign:2.1.0"
     exon            772..810
                     /gene="Loxl4"
                     /inference="alignment:Splign:2.1.0"
     exon            811..1030
                     /gene="Loxl4"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..1217
                     /gene="Loxl4"
                     /inference="alignment:Splign:2.1.0"
     exon            1218..1372
                     /gene="Loxl4"
                     /inference="alignment:Splign:2.1.0"
     exon            1373..1540
                     /gene="Loxl4"
                     /inference="alignment:Splign:2.1.0"
     exon            1541..1703
                     /gene="Loxl4"
                     /inference="alignment:Splign:2.1.0"
     exon            1704..1947
                     /gene="Loxl4"
                     /inference="alignment:Splign:2.1.0"
     exon            1948..2063
                     /gene="Loxl4"
                     /inference="alignment:Splign:2.1.0"
     exon            2064..2200
                     /gene="Loxl4"
                     /inference="alignment:Splign:2.1.0"
     exon            2201..2312
                     /gene="Loxl4"
                     /inference="alignment:Splign:2.1.0"
     exon            2313..3789
                     /gene="Loxl4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggataaaa agcccccagg gcgccggaga ggcccgttag cgctgctcag ccccggcgcc
       61 cggcccagcc ccgacctctg gatccagccg gtgccccgaa gtcaccatga tgtggccccc
      121 accacccacc ttctccgtgt tcctgctact gctgctaagc caagtcccct ccagcaggcc
      181 acagtcacca ggcaccaaga agctcaggct tgtgggccca gcgaacaggc cagaggaggg
      241 ccggctggag gtgctgcacc agggccagtg gggtacagtg tgtgatgatg actttgctct
      301 ccaggaggct acagtggcct gccgacaact gggctttgag tcagccttga cctgggcaca
      361 cagtgccaag tttggccaag gagagggccc catctggctg gacaatgtcc gttgtttggg
      421 caccgaggac accctagatc agtgtggctc taacggctgg ggtgtcagtg actgcagaca
      481 ctcagaagac gttggggtgg tgtgccatcc acggcgccag caggggtatc actctgagaa
      541 ggtctccaat gccctcgggc cccagggccg gcggctagaa gaggtgcggc tcaaacccat
      601 cctcgccagt gccaaaaggc acagcccagt aactgagggg gctgtggaag tacggtacga
      661 gggccactgg aggcaggtgt gtgaccaggg ctggaccatg aacaacagca gggttgtgtg
      721 cgggatgctg ggctttccca gtcaggcacc tgtcaacagc cactactaca gaaaagtctg
      781 gaatctgaag atgaaggatc ccaagtctag actcaatggc ctgacaaaga agaactcctt
      841 ctggattcac cgggttgact gtttggggac agaaccccac ttggccaagt gccaggtaca
      901 ggtggctcca ggaagaggca agctccggcc agcctgtccg ggcggcatgc acgctgtggt
      961 caactgtgtg gcagggccgc attttcagcg acagaagcca aagcctaagc gcaaggagtc
     1021 tggcgcagag caggagctga aagtgcgcct gcgctctggg gctcaggtgg gtgagggccg
     1081 tgtggaagtg ctcatgaacc gccagtgggg cacagtctgt gaccacaggt ggaacctcat
     1141 ctcagccagc gttgtgtgtc gccagcttgg ctttggctct gcccgggagg ccctttttgg
     1201 ggcccagttg ggccaagggc tagggcccat ccacctgagt gaagtgcgct gcaggggcta
     1261 tgagcagacc atcggcgact gccttgccct agaagggtcc cagaatggtt gtcaacatgc
     1321 aaatgacgct gctgtcaggt gcaacatccc tgacatgggc ttccagaaca aggtgcgctt
     1381 ggctggtggg cgcaactcgg aagagggcgt ggtggaggtg caggtggagg tgaatggggt
     1441 cccacgctgg gggactgtat gcagtgacca ctgggggctc actgaagcca tggtgacctg
     1501 tcggcaactc ggtctgggat ttgccaactt tgctatcaag gacacctggt actggcaggg
     1561 gacaccagag gccaaagaag tggtgatgag tggagttcgc tgctcaggca cagaaatggc
     1621 ccttcagcag tgtcagaggc atgggcctgt gcactgctcc cacggctcgg ggcgcttctc
     1681 ggccggcgtt gcctgcatga acagtgctcc agacctcgtg atgaatgccc agctggtaca
     1741 agaaacggcc tacttggagg atcgtccact cagcatgctg tactgcgctc atgaggaaaa
     1801 ctgtctctcc aagtccgctg accacatgga ctggccgtac ggacaccggc gcttgctgcg
     1861 cttctcctca cagatctaca accttggccg ggctgacttc cgtcccaagg ctggacgaca
     1921 cagctggatt tggcaccagt gccacaggca ctaccacagc atcgaggtct tcacccatta
     1981 tgacctgctc acactcaatg gttccaaagt ggctgagggg cacaaggcca gcttctgtct
     2041 agaagataca aactgcccct caggagtgca gcggcgctat gcgtgtgcta actttgggga
     2101 acagggagtg gctgtaggct gctgggacac ctaccggcac gacatcgatt gccagtgggt
     2161 ggatatcaca gatgtgagtc caggggacta tatcttccag gtggttgtga accccacaaa
     2221 tgatgtggca gaatcagact tctccaacaa catgattcga tgccgctgca agtatgacgg
     2281 gcagcgagtc tggctgcaca actgccacac aggagatccc taccgaccca atgcagagct
     2341 ctccctggag caggaacagc gactcaggaa caacttgatc taaagccgtt attgcacgcc
     2401 cccagctccg ctcacacacc agatacctca gcttactgga gccatgccct tcacaaagcc
     2461 ctgactcaca ggacaagggg ccagtgacaa ggagcaccaa gaagctgctc aggaagcctt
     2521 tcagtggcca gatcatcacc gggatggcag tactctcagg acggctctgg cccctccaga
     2581 gcacttatgg cctagatagc atggccttga ggctctgacc agctaaacct tctcttcctt
     2641 aaggagactc gacctttctt acaacttgat gcacagttcc cagcttcagg agctccaagt
     2701 tcctcaggga tgaactgtga ccaaggtcct ccctctctaa gtggtgcttc acaagtgtct
     2761 tggaggaaca caggacagag gagcagagaa cacaagaagt ggatggagtc agtcctctct
     2821 gctatgtgct ccatgcaaaa taaccatgtc aaagtcacac ctggcagaga ggctggtgaa
     2881 tgcagtccct ctgcttatcc tccctcagag gctctgaagc ctctccttgg cagttttacc
     2941 acacacacac acacacacac acacacgtac atttctaata cccctgaacc ctcaagcctc
     3001 ctgatggatc aacatcctga ttactggggc tgggggtggt ggtggcaagt tacccagaat
     3061 ggcaagacag ggcctttcct gaagagtagc aagaaatcaa gaagacagct gaggtcacaa
     3121 gttcagcctt tgaggacctc tgccaaggga gacaacagga agcccatatc tggcaggcag
     3181 tccagtctct tagaatcacc tacattgcaa ggttagccta aatttcagat ttaaccaagg
     3241 ccacttcacc ttaacaaact gagaagaact gcgatagaga agttggtcag tacagcccct
     3301 ctgcaggaac gccaaaacag gtctggtaga gttaggaaca caagactgag tcaacaagaa
     3361 gcaagaacgc ttaatttagt tcaggactga acctgggaaa agccaccatc cacagagagg
     3421 tggctgtgct ctgcttttgc tcaactggta taagatctga agtctttctg ggcatgcctg
     3481 gaccttttat ccatggacgt acacacggat gtcttctagg tcttataatc caataaaggc
     3541 tgctcattat gggctgctac agagaccaga gcagctgtac ttccgtagct cccagtgcat
     3601 tgcactctgc cctcttccct ccagagctgg atgatacgca gaacacattc cttggtacag
     3661 cccaccctaa cctgcttccc tgttacgctg cccgaggtca acagtgatcc tcgggtctgg
     3721 aaggcgagaa gtgaaaggga agaatgagaa ggtgcaaccc aaagactgta aacttttata
     3781 atagaggct
//
