LOCUS       NM_001001515            6177 bp    mRNA    linear   ROD 22-SEP-2024
DEFINITION  Rattus norvegicus LIM domain 7 (Lmo7), transcript variant 1, mRNA.
ACCESSION   NM_001001515 XM_341368
VERSION     NM_001001515.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6177)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 6177)
  AUTHORS   Dada,L.A., Trejo Bittar,H.E., Welch,L.C., Vagin,O.,
            Deiss-Yehiely,N., Kelly,A.M., Baker,M.R., Capri,J., Cohn,W.,
            Whitelegge,J.P., Vadasz,I., Gruenbaum,Y. and Sznajder,J.I.
  TITLE     High CO2 Leads to Na,K-ATPase Endocytosis via c-Jun Amino-Terminal
            Kinase-Induced LMO7b Phosphorylation
  JOURNAL   Mol Cell Biol 35 (23), 3962-3973 (2015)
   PUBMED   26370512
  REMARK    GeneRIF: JNK-dependent LMO7b phosphorylation is required for
            hypercapnia-mediated Na,K-ATPase endocytosis.
REFERENCE   3  (bases 1 to 6177)
  AUTHORS   Dedeic,Z., Cetera,M., Cohen,T.V. and Holaska,J.M.
  TITLE     Emerin inhibits Lmo7 binding to the Pax3 and MyoD promoters and
            expression of myoblast proliferation genes
  JOURNAL   J Cell Sci 124 (Pt 10), 1691-1702 (2011)
   PUBMED   21525034
REFERENCE   4  (bases 1 to 6177)
  AUTHORS   Kuo,J.C., Han,X., Hsiao,C.T., Yates,J.R. 3rd and Waterman,C.M.
  TITLE     Analysis of the myosin-II-responsive focal adhesion proteome
            reveals a role for beta-Pix in negative regulation of focal
            adhesion maturation
  JOURNAL   Nat Cell Biol 13 (4), 383-393 (2011)
   PUBMED   21423176
REFERENCE   5  (bases 1 to 6177)
  AUTHORS   Ebstein,F., Lange,N., Urban,S., Seifert,U., Kruger,E. and
            Kloetzel,P.M.
  TITLE     Maturation of human dendritic cells is accompanied by functional
            remodelling of the ubiquitin-proteasome system
  JOURNAL   Int J Biochem Cell Biol 41 (5), 1205-1215 (2009)
   PUBMED   19028597
REFERENCE   6  (bases 1 to 6177)
  AUTHORS   Tanaka-Okamoto,M., Hori,K., Ishizaki,H., Hosoi,A., Itoh,Y., Wei,M.,
            Wanibuchi,H., Mizoguchi,A., Nakamura,H. and Miyoshi,J.
  TITLE     Increased susceptibility to spontaneous lung cancer in mice lacking
            LIM-domain only 7
  JOURNAL   Cancer Sci 100 (4), 608-616 (2009)
   PUBMED   19215226
REFERENCE   7  (bases 1 to 6177)
  AUTHORS   Holaska,J.M., Rais-Bahrami,S. and Wilson,K.L.
  TITLE     Lmo7 is an emerin-binding protein that regulates the transcription
            of emerin and many other muscle-relevant genes
  JOURNAL   Hum Mol Genet 15 (23), 3459-3472 (2006)
   PUBMED   17067998
REFERENCE   8  (bases 1 to 6177)
  AUTHORS   Nakamura,H., Mukai,M., Komatsu,K., Tanaka-Okamoto,M., Itoh,Y.,
            Ishizaki,H., Tatsuta,M., Inoue,M. and Miyoshi,J.
  TITLE     Transforming growth factor-beta1 induces LMO7 while enhancing the
            invasiveness of rat ascites hepatoma cells
  JOURNAL   Cancer Lett 220 (1), 95-99 (2005)
   PUBMED   15737692
REFERENCE   9  (bases 1 to 6177)
  AUTHORS   Ooshio,T., Irie,K., Morimoto,K., Fukuhara,A., Imai,T. and Takai,Y.
  TITLE     Involvement of LMO7 in the association of two cell-cell adhesion
            molecules, nectin and E-cadherin, through afadin and alpha-actinin
            in epithelial cells
  JOURNAL   J Biol Chem 279 (30), 31365-31373 (2004)
   PUBMED   15140894
  REMARK    GeneRIF: LMO7 is an afadin- and alpha-actinin-binding protein that
            connects the nectin-afadin and E-cadherin-catenin systems through
            alpha-actinin.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On Sep 14, 2022 this sequence version replaced NM_001001515.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY533473.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06621351, SAMN09345238
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-283               JAXUCZ010000015.1  84981735-84982017
            284-354             JAXUCZ010000015.1  85048478-85048548
            355-424             JAXUCZ010000015.1  85062326-85062395
            425-531             JAXUCZ010000015.1  85087967-85088073
            532-562             JAXUCZ010000015.1  85121791-85121821
            563-676             JAXUCZ010000015.1  85123115-85123228
            677-875             JAXUCZ010000015.1  85127909-85128107
            876-1128            JAXUCZ010000015.1  85131638-85131890
            1129-1410           JAXUCZ010000015.1  85132776-85133057
            1411-2130           JAXUCZ010000015.1  85134665-85135384
            2131-2160           JAXUCZ010000015.1  85136298-85136327
            2161-2278           JAXUCZ010000015.1  85144080-85144197
            2279-2421           JAXUCZ010000015.1  85146181-85146323
            2422-3091           JAXUCZ010000015.1  85147569-85148238
            3092-3400           JAXUCZ010000015.1  85149772-85150080
            3401-3515           JAXUCZ010000015.1  85160124-85160238
            3516-3677           JAXUCZ010000015.1  85161362-85161523
            3678-3784           JAXUCZ010000015.1  85162571-85162677
            3785-3845           JAXUCZ010000015.1  85163595-85163655
            3846-3902           JAXUCZ010000015.1  85165268-85165324
            3903-3928           JAXUCZ010000015.1  85167457-85167482
            3929-4033           JAXUCZ010000015.1  85167775-85167879
            4034-4126           JAXUCZ010000015.1  85168472-85168564
            4127-4560           JAXUCZ010000015.1  85168941-85169374
            4561-4626           JAXUCZ010000015.1  85170139-85170204
            4627-4679           JAXUCZ010000015.1  85172935-85172987
            4680-4893           JAXUCZ010000015.1  85175358-85175571
            4894-5169           JAXUCZ010000015.1  85178990-85179265
            5170-5278           JAXUCZ010000015.1  85180931-85181039
            5279-5381           JAXUCZ010000015.1  85182446-85182548
            5382-6177           JAXUCZ010000015.1  85183756-85184551
FEATURES             Location/Qualifiers
     source          1..6177
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q21"
     gene            1..6177
                     /gene="Lmo7"
                     /note="LIM domain 7"
                     /db_xref="GeneID:361084"
                     /db_xref="RGD:1302984"
     exon            1..283
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     CDS             215..5404
                     /gene="Lmo7"
                     /EC_number="3.4.19.12"
                     /note="isoform 1 is encoded by transcript variant 1; LIM
                     domain only protein 7; TGF-beta induced protein; LIM
                     domain only 7"
                     /codon_start=1
                     /product="LIM domain only protein 7 isoform 1"
                     /protein_id="NP_001001515.2"
                     /db_xref="GeneID:361084"
                     /db_xref="RGD:1302984"
                     /translation="MEGMEDAEADCSVAFAEAQRWVEAVTEKNFETRDFRASLENGVL
                     LCDLINKLKPGVVRKINRLSTPIAGLDNINVFLKACEQIGLKEAQLFHPGDLQDLSNR
                     VTVKQEETDRRLKNVLITLYWLGRKAQNNPYYHGPYLNLKAFETLLGQALTKALEDSS
                     CLKRSGRDSGYGDIWCPDRGDFPAPPGSHRREDSFESLDSLGSRSLTSCSSDLTLRGG
                     REGCESDNDWEFTFKMQDYNKDDMSYRRISAIEPKSALPFNRFLPNKSKQPSYVPAPL
                     RKKRPDKNEDNRRSWASPVYTETEGTFSSTQRRAWGPKMENWHTVQETSTSSWCLEEE
                     EEKVTRLPNVVKDDLYVRKLSPVMPSPGSSFDQFLPKGWTPEDMNWKKIKRETYKPWY
                     KEFQGLSQFLLLQALQTYSDDILSSETNVKLDPTSGPRLITRRKNFSPTPGYRAHDLE
                     PQSLDPDLENDDFFVRKTRAFHANPCVLRAFEDFRRFSEPDDAVERDIILQCREGELV
                     LPDLEKDDMIVRRIPAQKKEVPLSGAPDRYQPVPFPEPWTLPPEIQAKFLSVLERTCP
                     PKDKPSSCRVLVPSHRLKKDDMLTRKIQSWKLGTAVPPISFRPGPCSEADLRKWEAIR
                     EASRLRHRKRLMVERLFQKIYGENGSKSLSDVSAEDVQSLRQLRYEEMQKIKSQLKEQ
                     DQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSDRSSKTFREMLQDRESQS
                     STTTSRRRIYSSDDILDDGVLPPTVTLSETSYQSERLEDKARAHPAEMPKEDSTTFAS
                     REDGIAAEIPLASHIPEERRQAPWPSAETRQASSSSAESHQASLPSTESDQARLPSAE
                     PHQASFSSAEPRQVPLVSAEPHQASSFSSTEPHQASLSSALQRPSSLSSSQQSWSTRG
                     ESTRISASLPRSYQRSDTARLTSVVTARPFGTSSRGISSLPRSYTMDDGWKYNGDVEV
                     VKREQHDSGRAAGMKPDSSHFILGSSSEKEVATGEDVASLSSFVLPSSSSLSHDQAAS
                     SKATFSSTSGLDSVSDSGEGRSSSLREVSRSPDQFSDMRISINQTPGTKHDFGFTIKW
                     DVSGISVASVEKGSPAEFSQLQVDDEILAINNTKFSYKDTKKWEEAMANAQETGNLVM
                     DVRRYGKSGSPETKWIDTTSGIYSTEKSSSLSVTTDFSESLQSPYSESKEINGIHEES
                     NAFDSKASESISLKNLKRRSQFFEQGSSDSVAPDLPVPTLSAPSRWAWDQEEERRRQE
                     RWQKEQDRLLQEKYQREQEKLREEWQRAQQEAERENSKYLDEELMVLNSNSISLTSRE
                     SVTASWEPSWSEGSKSLDREGTRAGDEDRGQLEDDAVYEDQSQKLQERLMLEHEKKRK
                     EQEAQEEELRKQREAEAQARAEAEAQARAEAQARAEAQAQAEAEARKRAEAQKLQAER
                     ERETSVKIYQYRRPIDSYDLPKREEESSGLLPIDRSKSRSTTELNDPLIEKSGSSKYS
                     DRIGTTSFSQRSSKKDQGPSEAELERQQILQEMRKKTSLHNDNSWIRQRSASVNKEPI
                     CLTGIMRRGESLDNLDSQRPGSWRQSSWHSQPAGVYASSSVQDFSRLPPQLLSTSNRA
                     YMRNPSSAVPPLAGSVKTSPGSPSPRSHSPSMSQSGSQLRNRSVSGKRVCSYCNSILG
                     KGAAMIIETLGLCYHLHCFKCVSCERDLGGSSSGAEVRIRNHQLYCNDCYLRFKSGRP
                     TAM"
     exon            284..354
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            355..424
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            425..531
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            532..562
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            563..676
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            677..875
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            876..1128
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            1129..1410
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            1411..2130
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            2131..2160
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            2161..2278
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            2279..2421
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            2422..3091
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            3092..3400
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            3401..3515
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            3516..3677
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            3678..3784
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            3785..3845
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            3846..3902
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            3903..3928
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            3929..4033
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            4034..4126
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            4127..4560
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            4561..4626
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            4627..4679
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            4680..4893
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            4894..5169
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            5170..5278
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            5279..5381
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
     exon            5382..6177
                     /gene="Lmo7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctgctcacc gcttccagtt gcctcttcac ctcctcctgc tccagtcctg ctggatttga
       61 gcggatttca ggagtttcga gaaagcaact cccgcaagtt ctcctaggtt cctgaactta
      121 aactgcacat cgctacaaag cgagggggac gcgtgggggc tcggagtccc ggcgcgcacc
      181 cactgagctg ctttctccct ctcttgccct agtcatggaa gggatggagg acgctgaggc
      241 cgattgctcc gttgcattcg cggaggctca gagatgggtg gaggctgtaa ctgagaagaa
      301 ttttgaaaca agggattttc gagcctctct ggaaaatggt gttctgttgt gtgatttgat
      361 taataagctc aaacccggag tcgttaggaa gatcaataga ctgtcgaccc cgatagcagg
      421 tttggataac ataaacgttt ttttgaaagc ttgtgaacag attggattga aagaagccca
      481 gctttttcat cccggggatc tacaggattt atcaaaccga gtcactgtca agcaagaaga
      541 gactgacagg agactgaaaa atgttttgat aactttatac tggctgggaa gaaaagcaca
      601 aaacaacccc tactatcatg gtccctatct caatttgaag gcttttgaga ctcttttagg
      661 acaagctttg actaaggcac ttgaagattc tagctgcctg aagagaagtg gccgggacag
      721 tggctacggg gatatctggt gtccggacag aggagacttt cctgcccctc ccgggagcca
      781 caggagggaa gattcctttg aaagcttgga ctccttgggg tctagatcac tgaccagctg
      841 ctcctcagac ctcactctca gaggcgggag ggaaggttgc gaaagtgaca acgattggga
      901 attcaccttc aaaatgcagg attataacaa agatgacatg tcctaccgac ggatttcggc
      961 cattgaaccg aagtcagctc taccattcaa tcgcttcttg cctaacaaaa gcaagcagcc
     1021 atcctatgtg ccagcgcctt tgaggaagaa gaggccagac aaaaatgagg ataatagaag
     1081 aagctgggct agccctgtct acacagaaac agagggaaca ttttcaagta cccagaggag
     1141 agcttggggt cccaagatgg agaactggca cacagttcaa gaaacttcca cctcctcttg
     1201 gtgtttagaa gaggaagaag aaaaagtcac acgcttgccc aatgttgtga aggacgatct
     1261 ctatgtgcgg aagcttagcc cagtcatgcc cagcccaggg agttctttcg atcaattcct
     1321 tcccaaaggc tggacccctg aagatatgaa ctggaaaaaa ataaaaagag agacttataa
     1381 gccatggtat aaggaatttc agggactcag tcagttttta ttgcttcagg ccctccaaac
     1441 ctactctgat gatatcttgt cttcggagac aaatgtcaaa ctcgatccta cctctggccc
     1501 gaggctcata actcgcagga agaacttttc tcccacccca ggctaccgag cccacgacct
     1561 cgagccgcaa tccctagatc ctgacttaga aaatgacgat ttctttgtca gaaaaacgag
     1621 ggctttccat gccaatccgt gtgttcttcg agccttcgaa gactttaggc ggttctccga
     1681 gccggacgat gctgtcgaac gcgatataat tttgcagtgt cgggaaggtg aactcgtact
     1741 tccggattta gaaaaggatg acatgattgt tcgcaggatc ccagctcaga agaaagaagt
     1801 gcccctttct ggggcgccag atagatacca gccagtcccc ttccctgaac cgtggactct
     1861 acctccagaa atccaagcga aatttctctc ggtgcttgaa aggacatgcc ctcccaaaga
     1921 caaaccaagt agctgtaggg tgttagtacc ttcccatcga ctgaagaaag acgacatgtt
     1981 gactcgcaag atccagtctt ggaagctggg gactgctgtg ccacccatca gcttcaggcc
     2041 tggcccctgc agcgaggccg acctacggaa gtgggaggcc atccgggagg ccagcagact
     2101 taggcacagg aagcggctga tggttgagag actctttcaa aagatttatg gtgagaacgg
     2161 gagcaagtcc ctgagcgatg tcagcgcaga ggatgttcag agcctgcgtc agctgcgcta
     2221 cgaggagatg cagaaaataa aatcccagtt gaaggagcaa gatcagaaat ggcaggatga
     2281 ccttgcgaaa tggaaagatc gccggaagag ttacacttca gacctgcaga agaaaaagga
     2341 ggagagggaa gaaattgaaa agcaggccct tgagaagtct gatcgaagct ccaagacatt
     2401 cagggaaatg ctgcaggaca gggaatctca aagttctaca actacatcta gaaggaggat
     2461 ctattcctct gatgacatcc tggatgatgg cgtgctccct cctacagtga ctctgtcaga
     2521 aactagttac cagagcgaga ggctagaaga caaggcaaga gctcatcctg ctgagatgcc
     2581 caaggaagat tccacaacat ttgcaagtag agaggacggt atagcagccg agatcccgct
     2641 tgcttctcat attcctgaag agcgacgtca ggccccttgg ccttctgcag aaacacgcca
     2701 ggcctcttca tcttccgcag aatcgcacca ggcctccttg ccttccacag aatcagacca
     2761 ggcccggttg ccatctgcag aaccgcacca ggcctctttc tcttctgcag aacctcgcca
     2821 ggtccctttg gtctctgcag aaccacacca ggcctcttct ttctcctcca cagaaccgca
     2881 ccaggcctct ttgtcttctg cactacagcg tccatcctca ctctcttctt ctcagcagtc
     2941 atggagcaca agaggagagt caactcggat ttcagcttct ctccctagaa gttaccagag
     3001 aagtgataca gccaggctaa catctgtggt cacagcgaga ccttttggca catcgtcacg
     3061 gggaatctca tcactgccca gatcctacac gatggatgat ggctggaaat acaatggaga
     3121 tgttgaagtt gtcaagagag agcaacatga ttcgggcaga gccgccggca tgaagcctga
     3181 ctccagccac tttattttgg gctcatctag tgagaaggag gtagccacag gagaagatgt
     3241 ggcaagcctg tcctctttcg tactcccttc ttcctcatct ctctcccacg accaggcagc
     3301 ctcctcaaaa gccacattct catcaacgtc tggcctggat tcagtgtctg actctggaga
     3361 agggagaagc tcatcactga gggaagtttc aaggtccccg gatcagttca gcgatatgag
     3421 aatcagcata aaccagacgc ccgggaccaa acatgacttt ggatttacaa taaaatggga
     3481 tgtttctggg atctctgtag catcagttga aaaaggtagc ccagcagaat tctctcagct
     3541 gcaggtagat gatgaaattc tcgccatcaa taacaccaag ttttcatata aggacacaaa
     3601 aaagtgggaa gaagctatgg caaatgccca agaaactgga aacttagtga tggatgtcag
     3661 gcgctacgga aagtccggtt cacccgaaac aaagtggatc gatacaactt caggaattta
     3721 cagcacagag aagtcttcaa gtctatcagt gacaactgat ttctctgaaa gccttcaaag
     3781 tccttattct gaatccaaag aaatcaatgg aattcatgag gagagcaacg cctttgattc
     3841 aaaagcatca gaatccattt ctttgaaaaa tttaaaaagg cgatcacaat tttttgaaca
     3901 aggaagctct gattctgtgg ctcctgatct tccggttcca accctcagtg ccccgagtcg
     3961 ctgggcttgg gatcaagagg aggagagacg gcggcaggag cggtggcaga aagagcaaga
     4021 tcgcctactg caggaaaaat accaacgtga gcaggagaag ctgagggaag agtggcagag
     4081 agctcagcag gaggcggaga gagagaattc caagtacctg gatgaggagc tgatggtcct
     4141 aaattccaac agcatttccc tgacctcccg ggagtctgtg actgcctcct gggaacccag
     4201 ctggagtgaa gggtccaagt ctctggacag ggaaggcacc cgagccggag atgaggaccg
     4261 gggacagctg gaagacgatg ctgtgtatga ggaccaaagt cagaagctgc aggaaaggct
     4321 catgcttgag catgagaaga aaaggaagga gcaagaggct caggaagagg agctccggaa
     4381 gcagcgggaa gctgaggctc aagctcgggc tgaggcagaa gcccaggcca gggccgaggc
     4441 tcaggcccgg gcagaggccc aggcccaggc cgaggctgag gctagaaaac gagctgaagc
     4501 acagaagctc caggcagaga gggaacgaga aacttcggtc aaaatatacc agtaccggag
     4561 gcctattgat tcctatgatc taccaaagag agaagaagaa tcttcagggc tgcttccaat
     4621 tgacaggagt aaatcaagat ctactacaga gctgaacgac cccctcatag agaagagtgg
     4681 aagcagcaaa tattcagatc gaattgggac cactagcttt tcacaaagga gttctaagaa
     4741 ggatcaaggc ccctcggaag cggagttgga gagacagcaa atccttcagg aaatgaggaa
     4801 gaaaacatct ctccacaatg acaacagctg gatccgacag cgcagtgcca gtgtaaacaa
     4861 ggagcccatc tgcctgactg ggatcatgag aagaggggag tctctggaca atctggattc
     4921 ccagcggcca ggatcttgga ggcagtcctc ctggcacagc cagcctgcag gagtctacgc
     4981 atcttcctct gttcaagact ttagtcgcct gccaccacag ctgttgtcca cgtcaaaccg
     5041 tgcctacatg cggaacccat cctctgcggt accgcctcta gctggctcag tgaagacctc
     5101 cccggggtct ccctctccac gtagccattc tccttcgatg tcacagtcag gctctcagct
     5161 acgtaacagg tcagtgagtg ggaaacgtgt gtgctcctac tgtaatagca ttctgggcaa
     5221 aggagccgcc atgatcatcg agaccctggg tctttgttat catttacatt gttttaagtg
     5281 tgtctcctgt gagcgtgacc tcggaggctc ttcctccgga gccgaagtca gaatccgaaa
     5341 ccaccaactg tactgcaatg actgctatct ccgattcaaa tctggccggc caaccgccat
     5401 gtgacgtaag cctccactca aaagcactgt tgcagataga agaggagacg gtggtcactg
     5461 aggcagaact ataaaaaatg gtgtatgttt tcccctcttt ttaaaaaaaa aaaaaaaaga
     5521 ataatctttg cctcgttaga tgacatagga acactgtggt gttggtagga cctgtatttt
     5581 tgttgtttat ttataagaag gtaattatgt gtgtgtgggg gaagagtgca gtatttacct
     5641 tttgaactca gcatcctaaa agcacaagtg ggaaacaaaa caaaactcaa gaacttaaaa
     5701 aaatacttct catgctgatg atctgatgat ctagtttgac ttttaagtgg tttttcaaag
     5761 agggtatttt gtttcaattt tttttaagtt cttaaacatt atttgaaata gttaatataa
     5821 atatgtaatt gtgtttgtct attataatgt attctaagtt aatgtggaac catatgaaaa
     5881 attttcacct aaatccaccc ataaatttgc tctttgtggc tttctttacc cagaaataat
     5941 ccagctgaaa agtgattttg cttatgtaat gttttatttg cttgaggagg gcactctgtt
     6001 ttctttacca ggactgttgt ggctaagcaa atgccagtag aaaagctgtt tattttcaat
     6061 aatgaaaaat aattgtggtt tgtataccgg taatttcctc cagaaactag tgagcgtctc
     6121 tgttcagttg cctttgtaaa taaaatttgt gatgcattta aggaacagtt tttaaaa
//
