LOCUS       NM_001115024            1257 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus lectin, mannose-binding 2 (Lman2), mRNA.
ACCESSION   NM_001115024
VERSION     NM_001115024.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1257)
  AUTHORS   Takeda,Y., Seko,A., Sakono,M., Hachisu,M., Koizumi,A., Fujikawa,K.
            and Ito,Y.
  TITLE     Parallel quantification of lectin-glycan interaction using
            ultrafiltration
  JOURNAL   Carbohydr Res 375, 112-117 (2013)
   PUBMED   23701871
REFERENCE   2  (bases 1 to 1257)
  AUTHORS   Shirakabe,K., Hattori,S., Seiki,M., Koyasu,S. and Okada,Y.
  TITLE     VIP36 protein is a target of ectodomain shedding and regulates
            phagocytosis in macrophage Raw 264.7 cells
  JOURNAL   J Biol Chem 286 (50), 43154-43163 (2011)
   PUBMED   22016386
  REMARK    Erratum:[J Biol Chem. 2012 Jun 1;287(23):19340]
REFERENCE   3  (bases 1 to 1257)
  AUTHORS   Reiterer,V., Nyfeler,B. and Hauri,H.P.
  TITLE     Role of the lectin VIP36 in post-ER quality control of human
            alpha1-antitrypsin
  JOURNAL   Traffic 11 (8), 1044-1055 (2010)
   PUBMED   20477988
REFERENCE   4  (bases 1 to 1257)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   5  (bases 1 to 1257)
  AUTHORS   Cao,Z., Li,C., Higginbotham,J.N., Franklin,J.L., Tabb,D.L.,
            Graves-Deal,R., Hill,S., Cheek,K., Jerome,W.G., Lapierre,L.A.,
            Goldenring,J.R., Ham,A.J. and Coffey,R.J.
  TITLE     Use of fluorescence-activated vesicle sorting for isolation of
            Naked2-associated, basolaterally targeted exocytic vesicles for
            proteomics analysis
  JOURNAL   Mol Cell Proteomics 7 (9), 1651-1667 (2008)
   PUBMED   18504258
REFERENCE   6  (bases 1 to 1257)
  AUTHORS   Breuza,L., Halbeisen,R., Jeno,P., Otte,S., Barlowe,C., Hong,W. and
            Hauri,H.P.
  TITLE     Proteomics of endoplasmic reticulum-Golgi intermediate compartment
            (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies
            ERGIC-32, a new cycling protein that interacts with human Erv46
  JOURNAL   J Biol Chem 279 (45), 47242-47253 (2004)
   PUBMED   15308636
REFERENCE   7  (bases 1 to 1257)
  AUTHORS   Shimada,O., Hara-Kuge,S., Yamashita,K., Tosaka-Shimada,H.,
            Yanchao,L., Yongnan,L., Atsumi,S. and Ishikawa,H.
  TITLE     Clusters of VIP-36-positive vesicles between endoplasmic reticulum
            and Golgi apparatus in GH3 cells
  JOURNAL   Cell Struct Funct 28 (3), 155-163 (2003)
   PUBMED   12951436
  REMARK    GeneRIF: Results suggest that actin filaments are involved in
            glycoprotein transport between the endoplasmic reticulum and
            cis-Golgi cisterna by using vesicular integral membrane protein-36
            (VIP36).
REFERENCE   8  (bases 1 to 1257)
  AUTHORS   Fullekrug,J., Scheiffele,P. and Simons,K.
  TITLE     VIP36 localisation to the early secretory pathway
  JOURNAL   J Cell Sci 112 (Pt 17), 2813-2821 (1999)
   PUBMED   10444376
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC158808.1.
            
            On Mar 12, 2008 this sequence version replaced NM_001115024.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158808.1, FQ230263.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1257
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..1257
                     /gene="Lman2"
                     /gene_synonym="Vip36"
                     /note="lectin, mannose-binding 2"
                     /db_xref="GeneID:290994"
                     /db_xref="RGD:1308965"
     exon            1..214
                     /gene="Lman2"
                     /gene_synonym="Vip36"
                     /inference="alignment:Splign:2.1.0"
     CDS             13..1089
                     /gene="Lman2"
                     /gene_synonym="Vip36"
                     /note="Vesicular integral-membrane protein 36; vesicular
                     integral-membrane protein VIP36"
                     /codon_start=1
                     /product="vesicular integral-membrane protein VIP36
                     precursor"
                     /protein_id="NP_001108496.1"
                     /db_xref="GeneID:290994"
                     /db_xref="RGD:1308965"
                     /translation="MAAEAWLWRWGWGWGQRCPGRPGLPGPGPGPTTFLHFLLLLGLV
                     AADITDGNSEHLKREHSLIKPYQGVGSSSMPLWDFQGSTMLTSQYVRLTPDERSKEGS
                     IWNHQPCFLKDWEMHVHFKVHGTGKKNLHGDGIALWYTRDRLVPGPVFGSKDNFHGLA
                     VFLDTYPNDETTERVFPYISVMVNNGSLSYDHSKDGRWSELAGCTADFRNRDHDTFLA
                     VRYSRGRLTVMTDLEDKNEWKNCIDVTGVRLPTGYYFGASAGTGDLSDNHDLISIKLF
                     QLTVERTPEEESIDWTKIEPGVNFLKSPKDNVDDPTGNFRGGPLTGWRVFLLLLCALL
                     GIIVCAVVGAVVFQKRQERNKRFY"
     exon            215..333
                     /gene="Lman2"
                     /gene_synonym="Vip36"
                     /inference="alignment:Splign:2.1.0"
     exon            334..451
                     /gene="Lman2"
                     /gene_synonym="Vip36"
                     /inference="alignment:Splign:2.1.0"
     exon            452..531
                     /gene="Lman2"
                     /gene_synonym="Vip36"
                     /inference="alignment:Splign:2.1.0"
     exon            532..693
                     /gene="Lman2"
                     /gene_synonym="Vip36"
                     /inference="alignment:Splign:2.1.0"
     exon            694..808
                     /gene="Lman2"
                     /gene_synonym="Vip36"
                     /inference="alignment:Splign:2.1.0"
     exon            809..928
                     /gene="Lman2"
                     /gene_synonym="Vip36"
                     /inference="alignment:Splign:2.1.0"
     exon            929..1231
                     /gene="Lman2"
                     /gene_synonym="Vip36"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagaaaagga gaatggcggc tgaggcctgg ctttggcgct ggggctgggg ctggggtcag
       61 cggtgcccag ggaggcctgg gcttcctggc cccggcccgg gccccactac atttctacat
      121 tttcttctgt tgctggggct ggtggctgcg gatataaccg acggcaacag tgaacacctc
      181 aagcgggagc actcgctcat caagccctac caaggagtcg gttccagttc catgccgctc
      241 tgggacttcc aaggcagcac gatgcttacg agccagtacg tgcgtctgac ccctgacgag
      301 cgcagcaaag agggctctat ttggaaccac cagccatgct tccttaagga ctgggaaatg
      361 catgtccact tcaaagtcca tggtaccggg aagaagaatc tccatggaga cggcatcgcc
      421 ttgtggtaca cccgagaccg ccttgtacca gggcctgtgt ttgggagcaa agacaacttc
      481 cacggtttgg ccgtcttctt ggacacatat cccaatgacg agaccactga gcgtgtgttc
      541 ccgtacatct cggtgatggt gaacaatggc tctctgtcgt atgatcacag caaagatggg
      601 cgctggagcg agttggcagg ctgcacggct gactttcgca accgggacca cgacaccttc
      661 ctagctgtgc gctattcccg gggccgcctc acggtgatga ccgacctgga ggacaagaac
      721 gagtggaaga actgcatcga tgtcacaggg gtgcgcctgc ctactggcta ctactttgga
      781 gcctctgctg gcaccggcga cctgtctgac aaccacgacc tcatctccat caagctgttc
      841 cagctcacag tagagcgcac acctgaggag gagagcatcg actggaccaa gatcgagcct
      901 ggtgtcaact tcctcaagtc ccctaaagac aatgtggatg accccactgg aaacttccga
      961 ggtgggcccc tgacggggtg gagggtgttc ctgctgctgc tctgcgccct cctgggcatc
     1021 atcgtctgtg ctgtggtggg cgccgtggtg tttcagaagc gccaggagcg gaacaagcgt
     1081 ttctactgag agaggccggt ttggctggga agggcctgac ctttgggtca gggctctcac
     1141 gtgaactctt ttctactggg attgtaaaaa ccaagcaacc ttatttctta actgtttcga
     1201 agaaataatt aaagtatttt cgtacatttt gaaaaaaaaa aaaaaaaaaa aaaaaaa
//
