LOCUS       NM_001105899            2071 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus lipase I (Lipi), mRNA.
ACCESSION   NM_001105899 XM_001067301 XM_221732
VERSION     NM_001105899.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2071)
  AUTHORS   Hiramatsu T, Sonoda H, Takanezawa Y, Morikawa R, Ishida M, Kasahara
            K, Sanai Y, Taguchi R, Aoki J and Arai H.
  TITLE     Biochemical and molecular characterization of two phosphatidic
            acid-selective phospholipase A1s, mPA-PLA1alpha and mPA-PLA1beta
  JOURNAL   J Biol Chem 278 (49), 49438-49447 (2003)
   PUBMED   12963729
REFERENCE   2  (bases 1 to 2071)
  AUTHORS   Wen XY, Hegele RA, Wang J, Wang DY, Cheung J, Wilson M, Yahyapour
            M, Bai Y, Zhuang L, Skaug J, Young TK, Connelly PW, Koop BF, Tsui
            LC and Stewart AK.
  TITLE     Identification of a novel lipase gene mutated in lpd mice with
            hypertriglyceridemia and associated with dyslipidemia in humans
  JOURNAL   Hum Mol Genet 12 (10), 1131-1143 (2003)
   PUBMED   12719377
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473989.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_221732.4, XM_001067301.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383, SAMEA5760434
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2071
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11p11"
     gene            1..2071
                     /gene="Lipi"
                     /note="lipase I"
                     /db_xref="GeneID:288322"
                     /db_xref="RGD:1310162"
     exon            1..159
                     /gene="Lipi"
                     /inference="alignment:Splign:2.1.0"
     CDS             114..1544
                     /gene="Lipi"
                     /EC_number="2.7.11.30"
                     /note="lipase, member H; lipase, member I"
                     /codon_start=1
                     /product="lipase member I precursor"
                     /protein_id="NP_001099369.1"
                     /db_xref="GeneID:288322"
                     /db_xref="RGD:1310162"
                     /translation="MRIYTFLCWICWVRFGYLNFPSKSNGGSKNPENNRTCLEFSKSN
                     AMNSLKDLFYPTVKINLLMYSRNNAKCAEPLFESNNSVNARFNPSKKTIWIIHGYRPL
                     GSTPMWIHKFTKAFLKQEDVNLIVVDWNQGATTFIYGRAVKNTRKVAEILREYIENLL
                     IHGASLDNFHFIGMSLGAHICGFVGKLFQGQLGRITGLDPAGPKFSGKPSNCRLDYTD
                     AKFVDVIHSDSQGFGILEPSGHIDFYPNGGRNQPGCPTSLLSGMDYIKCDHQRAVHLF
                     LEAFETNCNFVSFPCRSYRDYKSGLCVGCGNLYKDSCPRLGIQANLWKEELKKKTEEW
                     PLRTTAFLDTSSQNPFCTYYFALNIVALNETMKNGSLSFGLLKDLGVLEYPRLYVKTM
                     PFANLQEVKILAQFVNDIVNISRISMTYYQSTSPFCPTCEYRIKSLVFKSLTHPERPP
                     ICKYDFVLKERARIDLQPDECKKQTG"
     exon            160..207
                     /gene="Lipi"
                     /inference="alignment:Splign:2.1.0"
     exon            208..593
                     /gene="Lipi"
                     /inference="alignment:Splign:2.1.0"
     exon            594..702
                     /gene="Lipi"
                     /inference="alignment:Splign:2.1.0"
     exon            703..804
                     /gene="Lipi"
                     /inference="alignment:Splign:2.1.0"
     exon            805..894
                     /gene="Lipi"
                     /inference="alignment:Splign:2.1.0"
     exon            895..1062
                     /gene="Lipi"
                     /inference="alignment:Splign:2.1.0"
     exon            1063..1167
                     /gene="Lipi"
                     /inference="alignment:Splign:2.1.0"
     exon            1168..1279
                     /gene="Lipi"
                     /inference="alignment:Splign:2.1.0"
     exon            1280..1456
                     /gene="Lipi"
                     /inference="alignment:Splign:2.1.0"
     exon            1457..2071
                     /gene="Lipi"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 catttttaca gggaagcttg ctggagggag acaatcctat cacacaagga ccttaacgaa
       61 ttacggaagt ttttggtgaa acctagtgtt tcttttacag tttctgattc caaatgagaa
      121 tatacacttt tctgtgttgg atatgctggg taagatttgg gtatttaaat tttccatcga
      181 aaagcaatgg agggtctaaa aatcccgaga ataatagaac atgtcttgaa ttctcaaagt
      241 caaatgcaat gaattccttg aaagatttat tttatcccac agtaaagata aatctgctga
      301 tgtactcaag gaacaatgct aagtgtgcag aaccactctt tgagtctaat aactcagtta
      361 atgcccgttt caacccatcg aagaaaacca tctggattat tcatgggtac aggccgcttg
      421 gttccacccc aatgtggata cataagttta ctaaggcctt tttgaaacag gaagatgtga
      481 atctcattgt cgtagactgg aaccagggcg ctacgacttt tatttacggt agagcggtta
      541 aaaatacaag aaaagttgcg gagattttga gagagtacat tgaaaatctt ttgatccatg
      601 gagcatctct tgacaatttt catttcattg gcatgagctt aggggctcat atttgtggct
      661 ttgtaggaaa gctatttcag ggtcaacttg gaagaattac aggccttgat ccagctggac
      721 caaaattttc tggaaagcca tcaaattgca gattagatta tacagatgca aagtttgtag
      781 atgttatcca ctctgactcc caaggttttg gtattctaga accatcggga cacattgatt
      841 tttatccaaa tggtgggaga aatcagccag gttgtcctac atctcttttg tcaggaatgg
      901 attacattaa atgtgaccat cagcgagcag ttcacttgtt cctggaagct tttgaaacaa
      961 actgcaattt tgtttcattt ccatgtcgtt cctacagaga ttacaagagt ggtttgtgtg
     1021 tgggctgtgg gaatctttac aaagactcct gcccaagact tggtattcaa gctaatctat
     1081 ggaaagagga gttgaagaaa aaaacagagg aatggcctct aaggaccact gcatttttgg
     1141 ataccagtag ccaaaatcca ttctgtactt attattttgc tctcaatata gtcgctttga
     1201 atgaaactat gaagaatggc tcactttcat ttggtttatt aaaggacctt ggagtattgg
     1261 aatacccgag gctctatgtg aagaccatgc catttgctaa tcttcaagaa gttaagattc
     1321 ttgctcagtt cgtaaatgat attgtgaata tttcccgcat ttccatgaca tattatcagt
     1381 ccacaagtcc tttctgtccc acatgcgagt acagaataaa gagtctcgtg tttaaatctc
     1441 tcacacatcc agaaagacca ccaatttgta agtatgattt tgtacttaaa gaaagagcca
     1501 ggatagatct tcaaccagat gagtgtaaga aacagacggg gtgaacgcct tctttcttcc
     1561 agtttaaatt atggactgag aaaattgtca actggagcaa tgtaagcagg cacagactag
     1621 aatggctagt caatctgtga ttaggtatat ccattttaat acattttaaa gaataaaaat
     1681 tagaaaacaa agtgtgcaca cgccaaaaat gcattctgca tatatcctaa agctgttgtt
     1741 tctccttacc tgcttcctaa gtgaaattca acatcaaatg tttacatctg ctacttagcc
     1801 tactaataag tgagtatgtt aaagcacagt tcctaaggaa aatgagaagc tttttgagtg
     1861 ctttgcagtg gggcaaattc agtatcactg aacatctcta ttatggaaaa acagtttttt
     1921 acattcgaaa atatgtttag tgaaataagt tgagattatg tgaatcttgt gaatatgaag
     1981 aacttgttat gcactgcaaa taacgacgtt gtgctagggt gctcaataaa ttaatatttt
     2041 atgcacctac ctggcttaag atgaaatcct t
//
