LOCUS       NM_001400228            2505 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus lines homolog 1 (Lins1), mRNA.
ACCESSION   NM_001400228 XM_006229358
VERSION     NM_001400228.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2505)
  AUTHORS   Akawi,N.A., Al-Jasmi,F., Al-Shamsi,A.M., Ali,B.R. and Al-Gazali,L.
  TITLE     LINS, a modulator of the WNT signaling pathway, is involved in
            human cognition
  JOURNAL   Orphanet J Rare Dis 8, 87 (2013)
   PUBMED   23773660
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jan 20, 2022 this sequence version replaced XM_006229358.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360172.651170.1,
                                           SRR26360181.2146292.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-104               JAXUCZ010000001.1  129677876-129677979
            105-604             JAXUCZ010000001.1  129698070-129698569
            605-694             JAXUCZ010000001.1  129698657-129698746
            695-836             JAXUCZ010000001.1  129699325-129699466
            837-1424            JAXUCZ010000001.1  129700170-129700757
            1425-1596           JAXUCZ010000001.1  129701832-129702003
            1597-2505           JAXUCZ010000001.1  129702923-129703831
FEATURES             Location/Qualifiers
     source          1..2505
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..2505
                     /gene="Lins1"
                     /gene_synonym="Lins; Lins2; RGD1308792"
                     /note="lines homolog 1"
                     /db_xref="GeneID:308704"
                     /db_xref="RGD:1308792"
     exon            1..104
                     /gene="Lins1"
                     /gene_synonym="Lins; Lins2; RGD1308792"
                     /inference="alignment:Splign:2.1.0"
     exon            105..604
                     /gene="Lins1"
                     /gene_synonym="Lins; Lins2; RGD1308792"
                     /inference="alignment:Splign:2.1.0"
     CDS             185..2413
                     /gene="Lins1"
                     /gene_synonym="Lins; Lins2; RGD1308792"
                     /note="lines homolog 2"
                     /codon_start=1
                     /product="protein Lines homolog 1"
                     /protein_id="NP_001387157.1"
                     /db_xref="GeneID:308704"
                     /db_xref="RGD:1308792"
                     /translation="MRYIVEIKMESVQEILDHLYRKVLLGATLEDDLHGYIVYLNPDL
                     SEQAVCTASSVARSDVRDVLDGMAGQHGVSILPEAQECSRRQLQTGRAWEVTLLQLTL
                     IDMVLSRVLSAETESRAKAGYRELTEVLLQSIELDSKLIRVLQNSDKLLSYLAAKCLA
                     SLLYFQLREKKMLSNSWVTFCQKHLSDSSEGGEAVHCLCVLAAVMKEIFKDAHSQRAE
                     SLKQLLTPFDNTFEAFYNSLFSQHFGNFKNPSNIISSLMCFLELLELLVASRIHLKLH
                     LRSQRMLFLKPHALDILAWPIPAFIKRKLVILIKKCLLCKVGEDFCRESVPTLMSPDH
                     LLDSDMLALADALLHAIHLGLWKALTVPGKPSCFGGDEVQPGCRLRAGPDHVTLRAAS
                     LITVKSLEIKFQNCTSATEMKADLQKFLPEFLAFLKPQLQPSLQLHNPCEWLSRVFIE
                     QDDDMLEAAKASLSIYLHLTREWDTSTSLTPEKEAWIHSTHGHGYNPHCIFLFFLKNI
                     AFDSTVLLDFLISSETCFLEYFVKYLKLLQKDWGHFLSTCQFFAAMESQCGVSVHDPF
                     PLPAHGTSTSYTAPHAPVGENACPWIPWAADASSEPQSQPKETHPVPTNGPPSRTPQS
                     LVDYDSSEPSDEEATDEPLANSKQTSLCQEMPGEIQDLPRTCKGKERSREPQARPLLS
                     AEPNSPFSDDGGVAPFLRTVRCLEELQRAIYRLQEKNLFPYNPAALLKLLKGVEAKCD
                     NV"
     exon            605..694
                     /gene="Lins1"
                     /gene_synonym="Lins; Lins2; RGD1308792"
                     /inference="alignment:Splign:2.1.0"
     exon            695..836
                     /gene="Lins1"
                     /gene_synonym="Lins; Lins2; RGD1308792"
                     /inference="alignment:Splign:2.1.0"
     exon            837..1424
                     /gene="Lins1"
                     /gene_synonym="Lins; Lins2; RGD1308792"
                     /inference="alignment:Splign:2.1.0"
     exon            1425..1596
                     /gene="Lins1"
                     /gene_synonym="Lins; Lins2; RGD1308792"
                     /inference="alignment:Splign:2.1.0"
     exon            1597..2505
                     /gene="Lins1"
                     /gene_synonym="Lins; Lins2; RGD1308792"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaggggccgg agaggccttc cgtggagtac ggtggcccgg agtgggcagc tatgggtgcg
       61 agtggccggg cgatggctga gtggccgggc cggatggcag ccaggcttca ctgaggagac
      121 agattaaaga ttcattgtat ttctaagcct tcaatattta taccttgtgg ctgttgaccc
      181 tcttatgaga tacattgtgg aaatcaaaat ggaaagtgtc caagaaattt tggatcactt
      241 atacaggaaa gtacttcttg gagccacgct tgaagatgac ctccatggtt acatcgttta
      301 cctcaaccca gatctctcag agcaagctgt ctgtacagcc tcctctgtgg ctcggtctga
      361 tgtcagggat gtgctggacg gcatggcagg ccagcacggg gtgagcatcc ttcctgaagc
      421 acaggagtgt tccaggagac agcttcagac gggcagggcc tgggaagtga cgctccttca
      481 gttaacactg attgacatgg tactgagccg cgtgctgtct gctgaaaccg agagccgtgc
      541 aaaggctggg tacagagagc taactgaagt ccttttgcag tccattgaac tggattccaa
      601 attgatccgt gtactccaga attccgataa gttgttgtcc tacctggctg ccaagtgcct
      661 ggcctcgctc ctgtatttcc agctgagaga gaagaaaatg ttaagtaatt cctgggtcac
      721 gttttgccag aagcatctct ctgattcctc tgagggtggt gaagcagtgc attgcctctg
      781 cgtccttgca gctgtgatga aggagatctt taaagatgca cattcacaga gagcagaaag
      841 tctaaagcag ctcttgactc cttttgacaa tacttttgaa gcgttctaca attccttatt
      901 ttctcagcat tttggaaact tcaagaaccc ctctaacata atcagcagcc tgatgtgctt
      961 tctggagttg ctcgagcttc tcgtagcctc cagaatccac ctgaaactgc accttaggag
     1021 ccagaggatg ttatttttga aaccccatgc tctagatatt cttgcctggc ctattccggc
     1081 ttttataaaa aggaaattgg ttatactcat caaaaagtgc cttctctgta aagtgggtga
     1141 agacttctgc cgtgaatctg tgcccaccct gatgtcacca gaccatcttc tggacagtga
     1201 catgcttgct ttagctgatg cacttctgca cgctatacat ttggggttgt ggaaggcact
     1261 gactgttcct ggaaagcctt cctgctttgg aggagatgaa gtgcaacctg gatgcagact
     1321 cagggctggt cctgatcacg tgaccctgag agcagcaagc ttaattacag tgaaatcctt
     1381 agaaatcaag ttccagaatt gtacctcagc aactgaaatg aaagctgacc tgcagaagtt
     1441 cctgcccgag ttcctggcct tcttaaagcc tcagcttcag ccctctctcc agttacacaa
     1501 cccgtgtgag tggctgtcca gggtcttcat agagcaggac gatgacatgc tggaggccgc
     1561 caaagcatcc ctgagcatct acctccactt gaccagagaa tgggacactt ctacaagtct
     1621 gaccccagaa aaggaagcat ggatccactc cacacatgga catggctaca accctcactg
     1681 tattttctta ttcttcttaa agaatatagc gtttgattct acagttcttc ttgacttctt
     1741 gatatcctca gaaacctgtt tccttgaata ctttgttaaa tatttaaaac tactgcagaa
     1801 agactggggc cactttctgt ccacctgcca gttctttgct gcaatggaat cacagtgcgg
     1861 agtaagtgtt catgatcctt tccccttacc tgcccatggc acaagcacca gctacacagc
     1921 acctcatgct cctgttggag aaaatgcttg cccctggatc ccctgggctg ctgatgcctc
     1981 ctctgaaccc cagagccagc ccaaggaaac tcacccagtg ccaactaatg gcccaccttc
     2041 ccggacacca cagagtctgg tagattatga cagctctgaa ccctctgatg aggaagccac
     2101 agatgagcct ttagcaaaca gcaaacagac atctttatgt caagaaatgc ctggggaaat
     2161 ccaggatctg cctaggacat gcaaaggaaa ggaacgtagc cgggagcctc aggcgaggcc
     2221 tctgctctct gcagagccca actctccctt ctctgatgat ggtggagttg ctccatttct
     2281 tcgtacagtg agatgccttg aggagctaca gcgagctatt taccgtttgc aggagaaaaa
     2341 tctctttccg tataacccag cggcacttct gaagttgttg aaaggtgtgg aggccaagtg
     2401 tgataatgtg tgagccctgg gtaacacagc aacatttgtc ctcaggtttg tttctcttta
     2461 tataaattgc ctatctaaga taaataaaaa caaaatctgc aaaaa
//
