LOCUS       NM_001076793            1146 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus leukocyte immunoglobulin like receptor A5
            (Lilra5), mRNA.
ACCESSION   NM_001076793 XM_001078701
VERSION     NM_001076793.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1146)
  AUTHORS   Mitchell,A., Rentero,C., Endoh,Y., Hsu,K., Gaus,K., Geczy,C.,
            McNeil,H.P., Borges,L. and Tedla,N.
  TITLE     LILRA5 is expressed by synovial tissue macrophages in rheumatoid
            arthritis, selectively induces pro-inflammatory cytokines and IL-10
            and is regulated by TNF-alpha, IL-10 and IFN-gamma
  JOURNAL   Eur J Immunol 38 (12), 3459-3473 (2008)
   PUBMED   19009525
REFERENCE   2  (bases 1 to 1146)
  AUTHORS   Hoelsbrekken,S.E., Fossum,S. and Dissen,E.
  TITLE     Molecular cloning of LILRC1 and LILRC2 in the mouse and the rat,
            two novel immunoglobulin-like receptors encoded by the leukocyte
            receptor gene complex
  JOURNAL   Immunogenetics 57 (7), 479-486 (2005)
   PUBMED   16041585
  REMARK    GeneRIF: LILRC1 and LILRC2 both have two extracellular Ig-like
            domains and a cytoplasmic tail devoid of any known signaling
            motifs. The transmembrane regions contain an arginine residue.
REFERENCE   3  (bases 1 to 1146)
  AUTHORS   Borges,L., Kubin,M. and Kuhlman,T.
  TITLE     LIR9, an immunoglobulin-superfamily-activating receptor, is
            expressed as a transmembrane and as a secreted molecule
  JOURNAL   Blood 101 (4), 1484-1486 (2003)
   PUBMED   12393390
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            [WARNING] On May 8, 2024 this sequence was replaced by
            NM_001076793.3.
            
            On Nov 27, 2020 this sequence version replaced NM_001076793.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY998481.1, SRR26360172.394524.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-38                JAXUCZ010000001.1  79050074-79050111   c
            39-74               JAXUCZ010000001.1  79049887-79049922   c
            75-359              JAXUCZ010000001.1  79049435-79049719   c
            360-665             JAXUCZ010000001.1  79048992-79049297   c
            666-716             JAXUCZ010000001.1  79046104-79046154   c
            717-1146            JAXUCZ010000001.1  79045546-79045975   c
FEATURES             Location/Qualifiers
     source          1..1146
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..1146
                     /gene="Lilra5"
                     /gene_synonym="Lilrc1"
                     /note="leukocyte immunoglobulin like receptor A5"
                     /db_xref="GeneID:691533"
                     /db_xref="RGD:1582781"
     exon            1..38
                     /gene="Lilra5"
                     /gene_synonym="Lilrc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             5..892
                     /gene="Lilra5"
                     /gene_synonym="Lilrc1"
                     /note="leukocyte immunoglobulin-like receptor subfamily A
                     member 5; leukocyte immunoglobulin-like receptor,
                     subfamily A (with TM domain), member 5"
                     /codon_start=1
                     /product="leukocyte immunoglobulin-like receptor subfamily
                     A member 5 precursor"
                     /protein_id="NP_001070261.1"
                     /db_xref="GeneID:691533"
                     /db_xref="RGD:1582781"
                     /translation="MTFIFTAVLYLGLNLGQETSGLEGNPHKPTLSVQPGSLVARGKQ
                     VTILCEVTTGAQEYRLFKEGGPHPWRTKNTPKATNKAQFLISSIEQQHGGIYRCYYKT
                     PSGWSEHSDPLELVVTGLYSKPSLSIQSSTVVTSGETVTLQCVSQLGFNRFVLTKEGE
                     QKPSLIRDSEFINSTGQFQGLFPMGPVILSQRWMFRCYGYYVNSPQVWSEPSDLLEIH
                     VSEAAQPLGLSPNISHPKTVSQHQDYTMENLIRMGVSVFILVILGILLFEAQHSQRRT
                     QHAAGRESSTFFMVAETWG"
     exon            39..74
                     /gene="Lilra5"
                     /gene_synonym="Lilrc1"
                     /inference="alignment:Splign:2.1.0"
     exon            75..359
                     /gene="Lilra5"
                     /gene_synonym="Lilrc1"
                     /inference="alignment:Splign:2.1.0"
     exon            360..665
                     /gene="Lilra5"
                     /gene_synonym="Lilrc1"
                     /inference="alignment:Splign:2.1.0"
     exon            666..716
                     /gene="Lilra5"
                     /gene_synonym="Lilrc1"
                     /inference="alignment:Splign:2.1.0"
     exon            717..1146
                     /gene="Lilra5"
                     /gene_synonym="Lilrc1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgccatgacc ttcatcttca cagccgtgct ctatctgggg ctgaatctgg gccaagagac
       61 ctcggggttg gaagggaatc cccacaagcc aaccctcagt gttcagccag gatcattggt
      121 tgccagaggg aagcaggtga ccatcttatg tgaagtgacg acaggggccc aggaataccg
      181 tctttttaaa gaggggggtc cacatccttg gcgcacaaag aacactccaa aggccacaaa
      241 caaggctcag ttcttgatct catcaattga acaacaacat ggagggatat accgctgtta
      301 ctataagacc ccttcagggt ggtcagagca cagtgatcct ctagagcttg tagtgacagg
      361 actctatagt aaacccagcc tatccatcca gtccagcact gtggtgacct caggggagac
      421 tgtgacactt cagtgtgtct cacaactggg atttaacagg tttgttctga ctaaggaagg
      481 agaacagaag ccgtccttga tccgggactc agagtttata aactctactg ggcaattcca
      541 gggcctgttt cctatgggcc ctgtgatcct cagccagagg tggatgttca gatgttatgg
      601 ctattatgtc aacagccccc aagtgtggtc agaacccagc gatctcttgg aaatacatgt
      661 gtcagaagca gctcagcccc tcgggctatc accaaacata tcacacccca agacagtctc
      721 acagcaccag gattacacga tggagaatct catcaggatg ggggtgtcag tcttcattct
      781 tgtgattctt ggcattctgc tgtttgaagc tcagcatagc caaagacgga cacaacatgc
      841 agcaggaaga gaaagcagta catttttcat ggtggcagag acctggggat aagtccaagg
      901 atctcaggtg gttctgtaag aaaaatctgg gactatagta gggaaccatt ttcagagaac
      961 atacaaggga ggaaaagtgg tttgagtgta gggaagcacc tgggtagtct ggtggaaagg
     1021 tcttctatag ccaatcattt ggctatctct tcaccttgat gtgtatgtta gctgacagtc
     1081 ttctctctct ttccacctcc aataaagaag aaggaacagt cttgtttcat cagtcaggtt
     1141 tgggtc
//
