LOCUS       NM_001009706            1687 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus phospholysine phosphohistidine inorganic
            pyrophosphate phosphatase (Lhpp), mRNA.
ACCESSION   NM_001009706 XM_341944
VERSION     NM_001009706.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1687)
  AUTHORS   Koike,E., Toda,S., Yokoi,F., Izuhara,K., Koike,N., Itoh,K.,
            Miyazaki,K. and Sugihara,H.
  TITLE     Expression of new human inorganic pyrophosphatase in thyroid
            diseases: its intimate association with hyperthyroidism
  JOURNAL   Biochem Biophys Res Commun 341 (3), 691-696 (2006)
   PUBMED   16430861
REFERENCE   2  (bases 1 to 1687)
  AUTHORS   Yokoi,F., Hiraishi,H. and Izuhara,K.
  TITLE     Molecular cloning of a cDNA for the human phospholysine
            phosphohistidine inorganic pyrophosphate phosphatase
  JOURNAL   J Biochem 133 (5), 607-614 (2003)
   PUBMED   12801912
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088448.1.
            
            On Jan 13, 2005 this sequence version replaced XM_341944.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088448.1, SRR8487227.14317.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1687
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q41"
     gene            1..1687
                     /gene="Lhpp"
                     /note="phospholysine phosphohistidine inorganic
                     pyrophosphate phosphatase"
                     /db_xref="GeneID:361663"
                     /db_xref="RGD:1359187"
     exon            1..135
                     /gene="Lhpp"
                     /inference="alignment:Splign:2.1.0"
     CDS             11..823
                     /gene="Lhpp"
                     /EC_number="3.6.1.1"
                     /codon_start=1
                     /product="phospholysine phosphohistidine inorganic
                     pyrophosphate phosphatase"
                     /protein_id="NP_001009706.1"
                     /db_xref="GeneID:361663"
                     /db_xref="RGD:1359187"
                     /translation="MAAWAERLSGVRGVLLDISGVLYDSGTGGGAAIAGSVEAVARLK
                     RSPLKVRFCTNESQKSRRELVGVLQRLGFDISEGEVTAPAPATCQILKERGLRPHLLI
                     HEGVRSEFDDIDMSNPNCVVIADAGEGFSYQNMNRAFQVLMELENPVLISLGKGRYYK
                     ETSGLMLDVGGYMKALEYACGIEAEVVGKPSPEFFRSALQAIGVEAHQAIMIGDDIVG
                     DVGGAQQCGMRALQVRTGKFRPGDEHHPEVRADGYVDNLAEAVDLLLQHMDK"
     exon            136..323
                     /gene="Lhpp"
                     /inference="alignment:Splign:2.1.0"
     exon            324..477
                     /gene="Lhpp"
                     /inference="alignment:Splign:2.1.0"
     exon            478..541
                     /gene="Lhpp"
                     /inference="alignment:Splign:2.1.0"
     exon            542..634
                     /gene="Lhpp"
                     /inference="alignment:Splign:2.1.0"
     exon            635..726
                     /gene="Lhpp"
                     /inference="alignment:Splign:2.1.0"
     exon            727..1640
                     /gene="Lhpp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctggacgcg atggccgcgt gggctgagcg gctgtcgggc gtacgggggg tgctgcttga
       61 tatctccggc gtgctgtatg acagcggcac aggcggcgga gctgctattg caggctctgt
      121 ggaggcggtg gcgagactga aacggtcccc gctgaaagtg agattctgca ccaatgagtc
      181 ccagaagtcc cggcgagagc tggtgggggt gcttcagcgg ctggggtttg acatctcaga
      241 aggagaggtg actgcccctg cgccagccac ctgccagatc ctgaaggagc gaggcctgcg
      301 gccacactta ctcatccatg aaggagtccg ctcagaattc gatgacattg atatgtccaa
      361 cccaaactgt gtggtgattg cggatgctgg ggaaggcttt tcctatcaga atatgaacag
      421 agccttccaa gtgctgatgg agctggaaaa ccccgtgctc atatccctgg gaaaaggacg
      481 ctattacaag gagacctctg gcctgatgct ggatgttgga ggttacatga aggcactcga
      541 gtatgcctgt ggtatcgagg ctgaagtggt ggggaaaccc tcccctgagt tcttcaggtc
      601 tgctctgcaa gccatagggg tggaagccca ccaggccatc atgattggcg atgacatcgt
      661 gggtgacgtt ggcggtgccc agcagtgcgg aatgagagct ctgcaggtgc ggaccgggaa
      721 gttcaggcct ggcgatgagc accatccaga agtgagggca gatgggtacg tggacaacct
      781 tgcagaagcc gtggacctgc tgctgcagca catggacaag tgaccggcct tccgagacag
      841 tggacgaggg cacccacagc tcccgtactc catcgctgca ccctcttcct acatattcca
      901 gaccccaggc tacccaaggc tttgccgatc ctgacccttg cccactgcac tgggcaggtg
      961 ctggaagttc taggatgctt gtccctgggc cagagccagc catccccttc ctcagcctcc
     1021 ctctactgac tccctgttaa cattcctccc tccctagagt ctgggcagag gtttgttccc
     1081 tgcctttatg gcctgctccc ctccctggca catgccatgt ttcccatagt gacattcagg
     1141 aagagacccg ttagacctcc agaaaataaa accctcaggc tgacaggtcc ctctgagact
     1201 gtctgagtct ctaaactcct ttagccacct ttggcacttg gtcctttaat tggcaccatt
     1261 caattggatc atgcattgac tcctcattga actctctgat gtgagggacc tacagaaaac
     1321 ccagagctga gccagcctgc ccaccaccca cagccctatc tggcttcagt cagagtgact
     1381 gatcagactc tgccccctac ccctgtccta ggaaccaatg ccagcccact gttcttcctg
     1441 ttcccctgag ttacccagac acaggctggg gcagctctca ggaaactgaa gatcagcctc
     1501 ccatagagca gaagtgccca cctctacagt caagggtgca ggcacagaaa gcaccttaga
     1561 gtccggatgg acagacttga atatgttgtt tccagtgcac agagcgacct aatggctcaa
     1621 taaacttggc ctcaacagtc aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1681 aaaaaaa
//
