LOCUS       NM_181383               1910 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus lengsin, lens protein with glutamine synthetase
            domain (Lgsn), mRNA.
ACCESSION   NM_181383
VERSION     NM_181383.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1910)
  AUTHORS   Wyatt,K., Gao,C., Tsai,J.Y., Fariss,R.N., Ray,S. and Wistow,G.
  TITLE     A role for lengsin, a recruited enzyme, in terminal differentiation
            in the vertebrate lens
  JOURNAL   J Biol Chem 283 (10), 6607-6615 (2008)
   PUBMED   18178558
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY280501.1.
            
            On Jun 3, 2003 this sequence version replaced NM_181383.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY280501.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMEA5760476
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1910
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q21"
     gene            1..1910
                     /gene="Lgsn"
                     /gene_synonym="Gluld1; Lgs"
                     /note="lengsin, lens protein with glutamine synthetase
                     domain"
                     /db_xref="GeneID:316304"
                     /db_xref="RGD:727925"
     exon            1..66
                     /gene="Lgsn"
                     /gene_synonym="Gluld1; Lgs"
                     /inference="alignment:Splign:2.1.0"
     CDS             37..1722
                     /gene="Lgsn"
                     /gene_synonym="Gluld1; Lgs"
                     /note="glutamate-ammonia ligase domain-containing protein
                     1; glutamate-ammonia ligase (glutamine synthase) domain
                     containing 1; glutamate-ammonia ligase (glutamine
                     synthetase) domain containing 1"
                     /codon_start=1
                     /product="lengsin"
                     /protein_id="NP_852048.1"
                     /db_xref="GeneID:316304"
                     /db_xref="RGD:727925"
                     /translation="MNDEGDLAQEDTTKDEANSTEGSRVNKLKRTRRKVTKPHLCSAD
                     GDEITMANSREMSRNQTADLSKPGSAESWSWHNAKDAQDQIPVVKSSLPSAGAPDAEF
                     NPNTDHTRDNAQSLILPQLSSRMKHIKQEMAKNHLQFVRFEATDLHGVSRSKSIPAQF
                     FQEKVIHGVFMPRGYLELMPNPKDNEVNHIRATCFNSDIVLMPELSTFRVLPWAERTA
                     RVICDTFTVTGEPLLTSPRYIAKRQLRQLQDAGFSLLSAFIYDFCIFGVPEVINSKTI
                     SFPASTLLSNHDQPFMQELVDGLYHTGANVESFSSSTRPGQMEICFLPEFGISSADNA
                     FTLRTGVQEVARRYNYIASLVIETGFCNSGILSHSIWDVSGKTNMFYSGSGVERLTLT
                     GKKWLAGLLKHSAALSCLMAPAVNCRKRYCKDSRDLKDSVPTTWGYNDNSCALNVKCH
                     GEKGTQIENKLGSATANPYLVLAATVAAGLDGLQSSDGAAAESDESQDLYQPEPSEIP
                     LKMEDALAALEQDECLKQALGETFIRYFVAMKKYELENEETDAEGNKFLEYFI"
     exon            67..199
                     /gene="Lgsn"
                     /gene_synonym="Gluld1; Lgs"
                     /inference="alignment:Splign:2.1.0"
     exon            200..355
                     /gene="Lgsn"
                     /gene_synonym="Gluld1; Lgs"
                     /inference="alignment:Splign:2.1.0"
     exon            356..522
                     /gene="Lgsn"
                     /gene_synonym="Gluld1; Lgs"
                     /inference="alignment:Splign:2.1.0"
     exon            523..1904
                     /gene="Lgsn"
                     /gene_synonym="Gluld1; Lgs"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttggcaagg ctgatttacc gtaagaaacg gttgacatga acgatgaagg ggaccttgca
       61 caggaggaca caacaaaaga tgaagcaaac tcgactgaag gcagcagggt gaacaagttg
      121 aaaaggacaa gaagaaaagt caccaaacca catctttgct cagcagatgg ggatgaaatc
      181 accatggcca attccaggga gatgtccaga aaccaaacag cagatctgag caaacctggc
      241 tctgctgagt cttggtcctg gcacaatgcc aaagacgccc aagatcagat accagtggta
      301 aaatcttcac ttcccagtgc tggtgctcct gatgctgaat tcaacccgaa tactgatcac
      361 actcgggaca atgctcagag tttgatcctg cctcaacttt cttctagaat gaaacacatc
      421 aaacaagaaa tggccaaaaa tcacctccag tttgtacgat ttgaagccac agacttgcac
      481 ggtgtctcca gatctaagag catccctgca caattttttc aagaaaaagt gatccatgga
      541 gttttcatgc cccgtggtta tctggaattg atgccgaacc ctaaggacaa tgaggtaaat
      601 cacatacgag ccacgtgctt caatagtgac atagtcctca tgccagagct gtcgaccttt
      661 agagtcttgc cttgggcaga gaggactgcg cgggtgattt gtgacacctt cactgtgacg
      721 ggcgagcctc tgctgacgtc ccctaggtac atcgccaaga ggcagttgcg ccagctgcag
      781 gatgccggct tctctctgct gtctgccttc atctatgatt tctgcatttt cggtgtgccc
      841 gaagtgatca attcaaagac catatctttt cctgcctcga cattactaag taatcatgac
      901 cagcccttca tgcaggagct ggttgacggc ttgtatcaca caggggcaaa tgtggagagc
      961 ttctcctctt ctaccaggcc tgggcaaatg gagatctgtt ttctcccgga gtttggcatt
     1021 agctcagcgg ataatgcctt caccctcaga acaggtgtcc aagaagtggc caggagatat
     1081 aactacatag caagccttgt aattgagact ggattctgca actcaggaat tttgtctcat
     1141 agcatctggg atgtgagcgg gaagacaaac atgttctaca gtggttctgg ggtggagagg
     1201 ctcacgctca ccgggaagaa gtggttggca ggcctgctga agcactctgc ggctctcagc
     1261 tgcctgatgg cccctgctgt caactgccgc aaacgctact gcaaggacag cagagacctg
     1321 aaggacagcg tgcccaccac gtggggatac aacgacaaca gctgtgcctt gaacgtcaag
     1381 tgtcatggtg aaaaaggcac ccagatagaa aataaattag gttcggcaac cgcgaaccct
     1441 tacctggtat tggccgctac tgtggcagca ggcttggatg gtcttcagag cagtgatggt
     1501 gctgcggctg aatccgatga gagccaggat ctctatcaac cagaaccttc cgagatccct
     1561 ttgaagatgg aagatgccct cgccgcccta gagcaagatg agtgtctgaa gcaggcactg
     1621 ggagagactt tcattcgcta ttttgttgcc atgaagaagt acgaactgga aaatgaagaa
     1681 acagacgcag agggaaataa attcctggag tattttatat aggatggaac tatagagatg
     1741 ttattatgac aagtagctag tttatcagaa tgaaaagatt gagcctttgc agttaacaac
     1801 actagacagc ttctgcccct cccccacgga ttactgggca gatgaaatgg gattggtgag
     1861 atcctgattt cagctataga caataaattt gtggtgaaac agcaaaaaaa
//
