LOCUS       NM_001108405             820 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus leukocyte cell-derived chemotaxin 2 (Lect2),
            mRNA.
ACCESSION   NM_001108405 XM_001068117 XM_341486
VERSION     NM_001108405.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 820)
  AUTHORS   Hung WY, Chang JH, Cheng Y, Chen CK, Chen JQ, Hua KT, Cheng CW,
            Hsiao M, Chung CL, Lee WJ and Chien MH.
  TITLE     Leukocyte Cell-Derived Chemotaxin 2 Retards Non-Small Cell Lung
            Cancer Progression Through Antagonizing MET and EGFR Activities
  JOURNAL   Cell Physiol Biochem 51 (1), 337-355 (2018)
   PUBMED   30453282
REFERENCE   2  (bases 1 to 820)
  AUTHORS   Okabe H, Delgado E, Lee JM, Yang J, Kinoshita H, Hayashi H, Tsung
            A, Behari J, Beppu T, Baba H and Monga SP.
  TITLE     Role of leukocyte cell-derived chemotaxin 2 as a biomarker in
            hepatocellular carcinoma
  JOURNAL   PLoS One 9 (6), e98817 (2014)
   PUBMED   24892551
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 820)
  AUTHORS   Okumura A, Suzuki T, Miyatake H, Okabe T, Hashimoto Y, Miyakawa T,
            Zheng H, Unoki-Kubota H, Ohno H, Dohmae N, Kaburagi Y, Miyazaki Y,
            Tanokura M and Yamagoe S.
  TITLE     Leukocyte cell-derived chemotaxin 2 is a zinc-binding protein
  JOURNAL   FEBS Lett 587 (5), 404-409 (2013)
   PUBMED   23352894
REFERENCE   4  (bases 1 to 820)
  AUTHORS   Ong HT, Tan PK, Wang SM, Hian Low DT, Ooi LL and Hui KM.
  TITLE     The tumor suppressor function of LECT2 in human hepatocellular
            carcinoma makes it a potential therapeutic target
  JOURNAL   Cancer Gene Ther 18 (6), 399-406 (2011)
   PUBMED   21394108
REFERENCE   5  (bases 1 to 820)
  AUTHORS   Phesse TJ, Parry L, Reed KR, Ewan KB, Dale TC, Sansom OJ and Clarke
            AR.
  TITLE     Deficiency of Mbd2 attenuates Wnt signaling
  JOURNAL   Mol Cell Biol 28 (19), 6094-6103 (2008)
   PUBMED   18644872
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474032.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_341486.2, XM_001068117.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ210968.1, BF550221.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..820
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..820
                     /gene="Lect2"
                     /note="leukocyte cell-derived chemotaxin 2"
                     /db_xref="GeneID:361205"
                     /db_xref="RGD:1305404"
     exon            1..195
                     /gene="Lect2"
                     /inference="alignment:Splign:2.1.0"
     CDS             150..605
                     /gene="Lect2"
                     /codon_start=1
                     /product="leukocyte cell-derived chemotaxin-2 precursor"
                     /protein_id="NP_001101875.1"
                     /db_xref="GeneID:361205"
                     /db_xref="RGD:1305404"
                     /translation="MFPTRILMSAALISTALAGPWANICASRSSNEIRTCDSYGCGQY
                     STQRTQRHHPGVDVLCSDGSVVYAPFTGKIVGQEKPYRNKNAINDGVRLSGRGFCVKI
                     FYIKPIKYKGSIRKGEKLGTLLPLQKVYPGIQSHVHIENCDSSDPTAYL"
     exon            196..292
                     /gene="Lect2"
                     /inference="alignment:Splign:2.1.0"
     exon            293..438
                     /gene="Lect2"
                     /inference="alignment:Splign:2.1.0"
     exon            439..820
                     /gene="Lect2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgactcattt tgttttccgt gtctcgtact aaacctcgga gaaacacggg attccaaagc
       61 ttaattacca gagaaggtgg actcagtcgt ggactgtgtg tgcatgggag caattctaac
      121 cagaggaaga aacgggaagc agaatccaga tgtttcccac aagaatcctc atgtcagctg
      181 ctttgatttc cactgccctg gcaggaccat gggctaacat atgtgccagc agatcttcca
      241 acgagatccg gacatgtgac agctatggct gtggacagta ctctactcaa agaacccaaa
      301 ggcatcatcc aggtgtggac gtcctgtgct cagatggatc tgtggtgtat gcgccattca
      361 cggggaagat agtgggccag gagaaaccct atagaaacaa aaacgccatc aatgatggcg
      421 tccgactgtc gggaagaggt ttctgcgtca aaattttcta cattaagcca attaagtata
      481 agggctctat cagaaaggga gagaagctgg gcaccttgct gcccctgcag aaagtttacc
      541 ctggcataca gtcgcatgta cacattgaaa actgtgactc cagtgatccc acggcatacc
      601 tgtaagcaga gacagaggcc agatcttctc aaattcccag aaactggaac acgtcctgct
      661 cctgaagaaa cgtgcattct aacagacgtg ccatcagtgt ggacacaatt ctgattccga
      721 ctcagcgtca ctctgatggg cgggctctga tctgcctgct gcctggaggg ccagggagtt
      781 ttatgtttcc gatttttaag ttctggggac tgaaattaaa
//
