LOCUS       NP_001101875             151 aa            linear   ROD 20-MAR-2023
DEFINITION  leukocyte cell-derived chemotaxin-2 precursor [Rattus norvegicus].
ACCESSION   NP_001101875 XP_001068117 XP_341487
VERSION     NP_001101875.1
DBSOURCE    REFSEQ: accession NM_001108405.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 151)
  AUTHORS   Hung WY, Chang JH, Cheng Y, Chen CK, Chen JQ, Hua KT, Cheng CW,
            Hsiao M, Chung CL, Lee WJ and Chien MH.
  TITLE     Leukocyte Cell-Derived Chemotaxin 2 Retards Non-Small Cell Lung
            Cancer Progression Through Antagonizing MET and EGFR Activities
  JOURNAL   Cell Physiol Biochem 51 (1), 337-355 (2018)
   PUBMED   30453282
REFERENCE   2  (residues 1 to 151)
  AUTHORS   Okabe H, Delgado E, Lee JM, Yang J, Kinoshita H, Hayashi H, Tsung
            A, Behari J, Beppu T, Baba H and Monga SP.
  TITLE     Role of leukocyte cell-derived chemotaxin 2 as a biomarker in
            hepatocellular carcinoma
  JOURNAL   PLoS One 9 (6), e98817 (2014)
   PUBMED   24892551
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 151)
  AUTHORS   Okumura A, Suzuki T, Miyatake H, Okabe T, Hashimoto Y, Miyakawa T,
            Zheng H, Unoki-Kubota H, Ohno H, Dohmae N, Kaburagi Y, Miyazaki Y,
            Tanokura M and Yamagoe S.
  TITLE     Leukocyte cell-derived chemotaxin 2 is a zinc-binding protein
  JOURNAL   FEBS Lett 587 (5), 404-409 (2013)
   PUBMED   23352894
REFERENCE   4  (residues 1 to 151)
  AUTHORS   Ong HT, Tan PK, Wang SM, Hian Low DT, Ooi LL and Hui KM.
  TITLE     The tumor suppressor function of LECT2 in human hepatocellular
            carcinoma makes it a potential therapeutic target
  JOURNAL   Cancer Gene Ther 18 (6), 399-406 (2011)
   PUBMED   21394108
REFERENCE   5  (residues 1 to 151)
  AUTHORS   Phesse TJ, Parry L, Reed KR, Ewan KB, Dale TC, Sansom OJ and Clarke
            AR.
  TITLE     Deficiency of Mbd2 attenuates Wnt signaling
  JOURNAL   Mol Cell Biol 28 (19), 6094-6103 (2008)
   PUBMED   18644872
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474032.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_341487.2, XP_001068117.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ210968.1, BF550221.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..151
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     Protein         1..151
                     /product="leukocyte cell-derived chemotaxin-2 precursor"
                     /calculated_mol_wt=14709
     sig_peptide     1..18
                     /inference="COORDINATES: ab initio prediction:SignalP:4.0"
                     /calculated_mol_wt=1907
     Region          51..147
                     /region_name="Peptidase_M23"
                     /note="Peptidase family M23; pfam01551"
                     /db_xref="CDD:460250"
     CDS             1..151
                     /gene="Lect2"
                     /coded_by="NM_001108405.1:150..605"
                     /db_xref="GeneID:361205"
                     /db_xref="RGD:1305404"
ORIGIN      
        1 mfptrilmsa alistalagp wanicasrss neirtcdsyg cgqystqrtq rhhpgvdvlc
       61 sdgsvvyapf tgkivgqekp yrnknaindg vrlsgrgfcv kifyikpiky kgsirkgekl
      121 gtllplqkvy pgiqshvhie ncdssdptay l
//
