LOCUS       NP_001101071             375 aa            linear   ROD 24-JUN-2024
DEFINITION  LIM domain-binding protein 1 [Rattus norvegicus].
ACCESSION   NP_001101071 XP_001058773 XP_219948
VERSION     NP_001101071.1
DBSOURCE    REFSEQ: accession NM_001107601.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 375)
  AUTHORS   van Tienen,L.M., Mieszczanek,J., Fiedler,M., Rutherford,T.J. and
            Bienz,M.
  TITLE     Constitutive scaffolding of multiple Wnt enhanceosome components by
            Legless/BCL9
  JOURNAL   Elife 6, e20882 (2017)
   PUBMED   28296634
  REMARK    Erratum:[Elife. 2017 Mar 30;6:e27150. doi: 10.7554/eLife.27150.
            PMID: 28358670]
            Publication Status: Online-Only
REFERENCE   2  (residues 1 to 375)
  AUTHORS   Costello,I., Nowotschin,S., Sun,X., Mould,A.W., Hadjantonakis,A.K.,
            Bikoff,E.K. and Robertson,E.J.
  TITLE     Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern
            anterior mesendoderm, node, and midline development
  JOURNAL   Genes Dev 29 (20), 2108-2122 (2015)
   PUBMED   26494787
REFERENCE   3  (residues 1 to 375)
  AUTHORS   Armour,S.M., Bennett,E.J., Braun,C.R., Zhang,X.Y., McMahon,S.B.,
            Gygi,S.P., Harper,J.W. and Sinclair,D.A.
  TITLE     A high-confidence interaction map identifies SIRT1 as a mediator of
            acetylation of USP22 and the SAGA coactivator complex
  JOURNAL   Mol Cell Biol 33 (8), 1487-1502 (2013)
   PUBMED   23382074
REFERENCE   4  (residues 1 to 375)
  AUTHORS   Song,S.H., Kim,A., Ragoczy,T., Bender,M.A., Groudine,M. and Dean,A.
  TITLE     Multiple functions of Ldb1 required for beta-globin activation
            during erythroid differentiation
  JOURNAL   Blood 116 (13), 2356-2364 (2010)
   PUBMED   20570862
REFERENCE   5  (residues 1 to 375)
  AUTHORS   Kusy,S., Gerby,B., Goardon,N., Gault,N., Ferri,F., Gerard,D.,
            Armstrong,F., Ballerini,P., Cayuela,J.M., Baruchel,A., Pflumio,F.
            and Romeo,P.H.
  TITLE     NKX3.1 is a direct TAL1 target gene that mediates proliferation of
            TAL1-expressing human T cell acute lymphoblastic leukemia
  JOURNAL   J Exp Med 207 (10), 2141-2156 (2010)
   PUBMED   20855495
REFERENCE   6  (residues 1 to 375)
  AUTHORS   Visvader,J.E., Mao,X., Fujiwara,Y., Hahm,K. and Orkin,S.H.
  TITLE     The LIM-domain binding protein Ldb1 and its partner LMO2 act as
            negative regulators of erythroid differentiation
  JOURNAL   Proc Natl Acad Sci U S A 94 (25), 13707-13712 (1997)
   PUBMED   9391090
REFERENCE   7  (residues 1 to 375)
  AUTHORS   Jurata,L.W. and Gill,G.N.
  TITLE     Functional analysis of the nuclear LIM domain interactor NLI
  JOURNAL   Mol Cell Biol 17 (10), 5688-5698 (1997)
   PUBMED   9315627
REFERENCE   8  (residues 1 to 375)
  AUTHORS   Bach,I., Carriere,C., Ostendorff,H.P., Andersen,B. and
            Rosenfeld,M.G.
  TITLE     A family of LIM domain-associated cofactors confer transcriptional
            synergism between LIM and Otx homeodomain proteins
  JOURNAL   Genes Dev 11 (11), 1370-1380 (1997)
   PUBMED   9192866
REFERENCE   9  (residues 1 to 375)
  AUTHORS   Agulnick,A.D., Taira,M., Breen,J.J., Tanaka,T., Dawid,I.B. and
            Westphal,H.
  TITLE     Interactions of the LIM-domain-binding factor Ldb1 with LIM
            homeodomain proteins
  JOURNAL   Nature 384 (6606), 270-272 (1996)
   PUBMED   8918878
REFERENCE   10 (residues 1 to 375)
  AUTHORS   Jurata,L.W., Kenny,D.A. and Gill,G.N.
  TITLE     Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting
            protein, is expressed early in neuronal development
  JOURNAL   Proc Natl Acad Sci U S A 93 (21), 11693-11698 (1996)
   PUBMED   8876198
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473986.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_001058773.1, XP_219948.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN06621351,
                              SAMN16676786 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     Protein         1..375
                     /product="LIM domain-binding protein 1"
                     /calculated_mol_wt=42648
     Region          34..235
                     /region_name="LIM_bind"
                     /note="LIM-domain binding protein; pfam01803"
                     /db_xref="CDD:426444"
     Region          300..328
                     /region_name="LID"
                     /note="LIM interaction domain (LID); pfam17916"
                     /db_xref="CDD:465564"
     CDS             1..375
                     /gene="Ldb1"
                     /coded_by="NM_001107601.1:647..1774"
                     /db_xref="GeneID:309447"
                     /db_xref="RGD:1310359"
ORIGIN      
        1 mldrdvgptp mypptylepg igrhtpygnq tdyrifelnk rlqnwteecd nlwwdaftte
       61 ffeddamlti tfcledgpkr ytigrtlipr yfrsifegga telyyvlkhp keafhsnfvs
      121 ldcdqgsmvt qhgkpmftqv cvegrlylef mfddmmrikt whfsirqhre liprsilamh
      181 aqdpqmldql sknitrcgls nstlnylrlc vilepmqelm srhktyslsp rdclktclfq
      241 kwqrmvappa eparqqpskr rkrkmsggst mssgggntnn snskkkspas tfalssqvpd
      301 vmvvgeptlm ggefgdeder litrlentqf daangidded sfnnspalga nspwnskpps
      361 sqesksenpt sqasq
//
