LOCUS       NM_001394269            2820 bp    mRNA    linear   ROD 28-JUL-2024
DEFINITION  Rattus norvegicus lipid droplet associated hydrolase (Ldah),
            transcript variant 2, mRNA.
ACCESSION   NM_001394269 XM_008764591
VERSION     NM_001394269.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2820)
  AUTHORS   Goo,Y.H., Son,S.H., Kreienberg,P.B. and Paul,A.
  TITLE     Novel lipid droplet-associated serine hydrolase regulates
            macrophage cholesterol mobilization
  JOURNAL   Arterioscler Thromb Vasc Biol 34 (2), 386-396 (2014)
   PUBMED   24357060
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Apr 8, 2021 this sequence version replaced XM_008764591.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ210061.1, SRR26360194.1701151.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-79                JAXUCZ010000006.1  36801359-36801437
            80-162              JAXUCZ010000006.1  36804590-36804672
            163-318             JAXUCZ010000006.1  36813309-36813464
            319-462             JAXUCZ010000006.1  36822566-36822709
            463-632             JAXUCZ010000006.1  36833218-36833387
            633-867             JAXUCZ010000006.1  36861281-36861515
            868-950             JAXUCZ010000006.1  36869788-36869870
            951-2820            JAXUCZ010000006.1  36884060-36885929
FEATURES             Location/Qualifiers
     source          1..2820
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q14"
     gene            1..2820
                     /gene="Ldah"
                     /gene_synonym="RGD1311648"
                     /note="lipid droplet associated hydrolase"
                     /db_xref="GeneID:313949"
                     /db_xref="RGD:1311648"
     exon            1..79
                     /gene="Ldah"
                     /gene_synonym="RGD1311648"
                     /inference="alignment:Splign:2.1.0"
     exon            80..162
                     /gene="Ldah"
                     /gene_synonym="RGD1311648"
                     /inference="alignment:Splign:2.1.0"
     exon            163..318
                     /gene="Ldah"
                     /gene_synonym="RGD1311648"
                     /inference="alignment:Splign:2.1.0"
     CDS             165..1142
                     /gene="Ldah"
                     /gene_synonym="RGD1311648"
                     /EC_number="3.1.1.13"
                     /note="UPF0554 protein C2orf43 homolog; lipid
                     droplet-associated serine hydrolase"
                     /codon_start=1
                     /product="lipid droplet-associated hydrolase"
                     /protein_id="NP_001381198.1"
                     /db_xref="GeneID:313949"
                     /db_xref="RGD:1311648"
                     /translation="MASEVEDGVPVHEEFFLCGGVETQIIKCGPWTNLFDKQGVSKPK
                     HLIFVIPGNPGLSPFYVPFAKALYSLVKGHFPVWIISHAGFCLTPKDKKILTAPQEPN
                     AQEIEDIYGLNGQIEHKIAFLRAHVPKDVKLIFIGHSVGSYIALHVMNRAPELPVVHT
                     FLLFPTIERMSESPNGKFATPFLCRFRYMLYAASYLIFKPCPEMIKSFIVQKVLEKMS
                     FKSELRLTDLLQPFCLANAAYLGGQEMIHVVKRDDGIIKELLPKLTFYYGKTDGWCPV
                     NYYEDMKRDFPEANLHLCEKGIPHAFVLGFSQEMAAMVADWINNRLPKK"
     exon            319..462
                     /gene="Ldah"
                     /gene_synonym="RGD1311648"
                     /inference="alignment:Splign:2.1.0"
     exon            463..632
                     /gene="Ldah"
                     /gene_synonym="RGD1311648"
                     /inference="alignment:Splign:2.1.0"
     exon            633..867
                     /gene="Ldah"
                     /gene_synonym="RGD1311648"
                     /inference="alignment:Splign:2.1.0"
     exon            868..950
                     /gene="Ldah"
                     /gene_synonym="RGD1311648"
                     /inference="alignment:Splign:2.1.0"
     exon            951..2820
                     /gene="Ldah"
                     /gene_synonym="RGD1311648"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctacaggcg ggacttccgg tcctggtgaa gctttgacaa gaggtccgcg gacgaccccg
       61 atactttgtg gatgggcaga catccagttt gaccagcacc atgcgttgaa gatgcttgct
      121 ttttctccat tgtataattt tggcttcttt gtcaaaaatc agaaatggcc tcagaagttg
      181 aggatggagt ccctgtgcat gaggaattct ttctctgtgg tggagttgaa acccagatca
      241 ttaaatgtgg gccctggact aacctctttg ataaacaagg tgtcagcaag ccaaaacatc
      301 ttatcttcgt cattcccggt aacccaggcc tttccccctt ctacgtgcca tttgcaaagg
      361 ccttgtactc tttggtgaag ggccacttcc cagtatggat catctcgcat gctgggtttt
      421 gcttgactcc caaggacaag aagattctca ctgcaccaca ggaaccaaat gctcaagaaa
      481 ttgaggacat ctatggtctg aatggtcaaa tagagcacaa aatagctttt ctgagagctc
      541 acgtaccgaa ggatgtgaag cttatattca ttggccattc cgtaggcagc tatattgctc
      601 ttcacgtgat gaaccgtgcc ccggagctgc cggtcgtcca cacctttctg ctgtttccaa
      661 ctatcgagcg aatgtccgaa tcgcccaacg gcaagtttgc cactccattt ttgtgccggt
      721 ttcgatatat gctctatgct gccagctact taatttttaa gccatgtcct gaaatgataa
      781 agtccttcat agtccaaaaa gtcctggaaa aaatgagctt taaatccgaa cttcgtttga
      841 cggatcttct tcaaccattc tgccttgcta atgctgccta cctcgggggc caagaaatga
      901 tccatgtggt gaagagagat gatggaatca taaaggaact tttacctaag cttacatttt
      961 actatggtaa aacagatggc tggtgtccag taaactacta tgaagacatg aagagagatt
     1021 ttccagaagc caatcttcac ctctgtgaga aaggaatacc ccatgctttt gttctcggtt
     1081 ttagccagga gatggctgcc atggttgctg actggataaa caatagactg cccaaaaaat
     1141 aagtactgtc ccaaggggga acaagagcac ccacaggcaa cacatagaag ctgtaggtgt
     1201 gctctgctta ggggtaaatg tttaatctta atgcttgaaa gaaaaattga gaccctcttg
     1261 tcttagagat taccagctcc caggccctgt gttaagacta aagtgaacac agctaatgac
     1321 tcattccatg gaagagcaat aagcagagga tgctgacggt gcactttgga gaaacccagt
     1381 tcaggggaaa ccatttcaga cttcatacag gtcctggctg agatcatcag caggatcttc
     1441 gtggtccacc tgcagtacac caaacatcag gtttgcccga cactcctcta ctaaccagac
     1501 agggttgctg gaagatcctg actctatcct gccacaggat agctaacagg ctgctcctga
     1561 cccctgaaat gccaggtccc tgcaggctct tccagagcga gaagggaggg atgaagagtc
     1621 cacatcggat ttgtatgggc atgggatttc ttgccagtgc aatccgccag tgacgctcca
     1681 tggacaggaa gcagtgagcc accctagcca ttcacgatgc cgttagctac cttgtgactc
     1741 ttcccttctc aaaatctcct agaacataaa tttggaaagg tgttttaaat tgttaagtaa
     1801 aacactagca taatttcatt ccccacgtgc ctaaacttta ttgatcggaa agaaatgatt
     1861 tttcaaatga acagaatcct gcaagccatt aaatttttat tacttcactt ctgaaagcat
     1921 caaagtcgag tagaaaagca tattcctgac taagaagcag aggggtgcat cctccaaaca
     1981 cactgaacag ctatgcggcc ttaccttaac tgactcaatc ctgagatctc ggaggccagt
     2041 taaacccagc cgtctgtagt aacagttgaa cagttagttg gaagcattcc attttcttgt
     2101 agaaaaaaag ctctcataac agtatcattc ctcaagggca gtgagatggt ccttcctctc
     2161 aaagacctaa ggcactgatg aaagatttgg ctctggtgtg ctgccagccc agtggtgaga
     2221 gaggagtagt tctcatcgct cggcatggct tccacatagg agctcagctt ctccagacaa
     2281 ggagtgctct cagtccagga agacaccgtg agggtcctta ctgtgtttgc acaaggaggc
     2341 ctcctgcaga gctgacctgg gaagccagga ttcttgctct gagtgccccg cttatagaac
     2401 aggcttgatc agtagtggga atcagtacat agaaacaaat cctggggggg ctggagaggt
     2461 ggctcagcgg ttaagagcac tgactgctct tccagaggtc ctgagttcaa atcccagcaa
     2521 ccacatggtg gctcacaacc atctgtaatg agatctgatg ccctcttctg gtgtgtctga
     2581 agacagctac aatgtactca tatataataa ataaataaat aaataaataa aaagaaagaa
     2641 acaaatcctg gtaaatcaga cctagtggaa caaaagagta gcattcgtag ctctctctta
     2701 gaaattattt tacattactc tttgtttccc aaatcctgtt taaaaggccc tggttcctca
     2761 ttcctactcc tcacctaatc accaaacaat attttataat aaatttctca cccgcagtca
//
