LOCUS       NM_001014075            2737 bp    mRNA    linear   ROD 28-JUL-2024
DEFINITION  Rattus norvegicus lipid droplet associated hydrolase (Ldah),
            transcript variant 1, mRNA.
ACCESSION   NM_001014075 XM_233973
VERSION     NM_001014075.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2737)
  AUTHORS   Goo,Y.H., Son,S.H., Kreienberg,P.B. and Paul,A.
  TITLE     Novel lipid droplet-associated serine hydrolase regulates
            macrophage cholesterol mobilization
  JOURNAL   Arterioscler Thromb Vasc Biol 34 (2), 386-396 (2014)
   PUBMED   24357060
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Apr 8, 2021 this sequence version replaced NM_001014075.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088848.1, SRR26360172.2276295.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-79                JAXUCZ010000006.1  36801359-36801437
            80-235              JAXUCZ010000006.1  36813309-36813464
            236-379             JAXUCZ010000006.1  36822566-36822709
            380-549             JAXUCZ010000006.1  36833218-36833387
            550-784             JAXUCZ010000006.1  36861281-36861515
            785-867             JAXUCZ010000006.1  36869788-36869870
            868-2737            JAXUCZ010000006.1  36884060-36885929
FEATURES             Location/Qualifiers
     source          1..2737
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q14"
     gene            1..2737
                     /gene="Ldah"
                     /gene_synonym="RGD1311648"
                     /note="lipid droplet associated hydrolase"
                     /db_xref="GeneID:313949"
                     /db_xref="RGD:1311648"
     exon            1..79
                     /gene="Ldah"
                     /gene_synonym="RGD1311648"
                     /inference="alignment:Splign:2.1.0"
     exon            80..235
                     /gene="Ldah"
                     /gene_synonym="RGD1311648"
                     /inference="alignment:Splign:2.1.0"
     CDS             82..1059
                     /gene="Ldah"
                     /gene_synonym="RGD1311648"
                     /EC_number="3.1.1.13"
                     /note="UPF0554 protein C2orf43 homolog; lipid
                     droplet-associated serine hydrolase"
                     /codon_start=1
                     /product="lipid droplet-associated hydrolase"
                     /protein_id="NP_001014097.1"
                     /db_xref="GeneID:313949"
                     /db_xref="RGD:1311648"
                     /translation="MASEVEDGVPVHEEFFLCGGVETQIIKCGPWTNLFDKQGVSKPK
                     HLIFVIPGNPGLSPFYVPFAKALYSLVKGHFPVWIISHAGFCLTPKDKKILTAPQEPN
                     AQEIEDIYGLNGQIEHKIAFLRAHVPKDVKLIFIGHSVGSYIALHVMNRAPELPVVHT
                     FLLFPTIERMSESPNGKFATPFLCRFRYMLYAASYLIFKPCPEMIKSFIVQKVLEKMS
                     FKSELRLTDLLQPFCLANAAYLGGQEMIHVVKRDDGIIKELLPKLTFYYGKTDGWCPV
                     NYYEDMKRDFPEANLHLCEKGIPHAFVLGFSQEMAAMVADWINNRLPKK"
     exon            236..379
                     /gene="Ldah"
                     /gene_synonym="RGD1311648"
                     /inference="alignment:Splign:2.1.0"
     exon            380..549
                     /gene="Ldah"
                     /gene_synonym="RGD1311648"
                     /inference="alignment:Splign:2.1.0"
     exon            550..784
                     /gene="Ldah"
                     /gene_synonym="RGD1311648"
                     /inference="alignment:Splign:2.1.0"
     exon            785..867
                     /gene="Ldah"
                     /gene_synonym="RGD1311648"
                     /inference="alignment:Splign:2.1.0"
     exon            868..2737
                     /gene="Ldah"
                     /gene_synonym="RGD1311648"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctacaggcg ggacttccgg tcctggtgaa gctttgacaa gaggtccgcg gacgaccccg
       61 atactttgtg gatgggcaga aatggcctca gaagttgagg atggagtccc tgtgcatgag
      121 gaattctttc tctgtggtgg agttgaaacc cagatcatta aatgtgggcc ctggactaac
      181 ctctttgata aacaaggtgt cagcaagcca aaacatctta tcttcgtcat tcccggtaac
      241 ccaggccttt cccccttcta cgtgccattt gcaaaggcct tgtactcttt ggtgaagggc
      301 cacttcccag tatggatcat ctcgcatgct gggttttgct tgactcccaa ggacaagaag
      361 attctcactg caccacagga accaaatgct caagaaattg aggacatcta tggtctgaat
      421 ggtcaaatag agcacaaaat agcttttctg agagctcacg taccgaagga tgtgaagctt
      481 atattcattg gccattccgt aggcagctat attgctcttc acgtgatgaa ccgtgccccg
      541 gagctgccgg tcgtccacac ctttctgctg tttccaacta tcgagcgaat gtccgaatcg
      601 cccaacggca agtttgccac tccatttttg tgccggtttc gatatatgct ctatgctgcc
      661 agctacttaa tttttaagcc atgtcctgaa atgataaagt ccttcatagt ccaaaaagtc
      721 ctggaaaaaa tgagctttaa atccgaactt cgtttgacgg atcttcttca accattctgc
      781 cttgctaatg ctgcctacct cgggggccaa gaaatgatcc atgtggtgaa gagagatgat
      841 ggaatcataa aggaactttt acctaagctt acattttact atggtaaaac agatggctgg
      901 tgtccagtaa actactatga agacatgaag agagattttc cagaagccaa tcttcacctc
      961 tgtgagaaag gaatacccca tgcttttgtt ctcggtttta gccaggagat ggctgccatg
     1021 gttgctgact ggataaacaa tagactgccc aaaaaataag tactgtccca agggggaaca
     1081 agagcaccca caggcaacac atagaagctg taggtgtgct ctgcttaggg gtaaatgttt
     1141 aatcttaatg cttgaaagaa aaattgagac cctcttgtct tagagattac cagctcccag
     1201 gccctgtgtt aagactaaag tgaacacagc taatgactca ttccatggaa gagcaataag
     1261 cagaggatgc tgacggtgca ctttggagaa acccagttca ggggaaacca tttcagactt
     1321 catacaggtc ctggctgaga tcatcagcag gatcttcgtg gtccacctgc agtacaccaa
     1381 acatcaggtt tgcccgacac tcctctacta accagacagg gttgctggaa gatcctgact
     1441 ctatcctgcc acaggatagc taacaggctg ctcctgaccc ctgaaatgcc aggtccctgc
     1501 aggctcttcc agagcgagaa gggagggatg aagagtccac atcggatttg tatgggcatg
     1561 ggatttcttg ccagtgcaat ccgccagtga cgctccatgg acaggaagca gtgagccacc
     1621 ctagccattc acgatgccgt tagctacctt gtgactcttc ccttctcaaa atctcctaga
     1681 acataaattt ggaaaggtgt tttaaattgt taagtaaaac actagcataa tttcattccc
     1741 cacgtgccta aactttattg atcggaaaga aatgattttt caaatgaaca gaatcctgca
     1801 agccattaaa tttttattac ttcacttctg aaagcatcaa agtcgagtag aaaagcatat
     1861 tcctgactaa gaagcagagg ggtgcatcct ccaaacacac tgaacagcta tgcggcctta
     1921 ccttaactga ctcaatcctg agatctcgga ggccagttaa acccagccgt ctgtagtaac
     1981 agttgaacag ttagttggaa gcattccatt ttcttgtaga aaaaaagctc tcataacagt
     2041 atcattcctc aagggcagtg agatggtcct tcctctcaaa gacctaaggc actgatgaaa
     2101 gatttggctc tggtgtgctg ccagcccagt ggtgagagag gagtagttct catcgctcgg
     2161 catggcttcc acataggagc tcagcttctc cagacaagga gtgctctcag tccaggaaga
     2221 caccgtgagg gtccttactg tgtttgcaca aggaggcctc ctgcagagct gacctgggaa
     2281 gccaggattc ttgctctgag tgccccgctt atagaacagg cttgatcagt agtgggaatc
     2341 agtacataga aacaaatcct gggggggctg gagaggtggc tcagcggtta agagcactga
     2401 ctgctcttcc agaggtcctg agttcaaatc ccagcaacca catggtggct cacaaccatc
     2461 tgtaatgaga tctgatgccc tcttctggtg tgtctgaaga cagctacaat gtactcatat
     2521 ataataaata aataaataaa taaataaaaa gaaagaaaca aatcctggta aatcagacct
     2581 agtggaacaa aagagtagca ttcgtagctc tctcttagaa attattttac attactcttt
     2641 gtttcccaaa tcctgtttaa aaggccctgg ttcctcattc ctactcctca cctaatcacc
     2701 aaacaatatt ttataataaa tttctcaccc gcagtca
//
