LOCUS       XM_039091133            3585 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus lamin B receptor (Lbr), transcript
            variant X4, mRNA.
ACCESSION   XM_039091133
VERSION     XM_039091133.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051348.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039091133.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3585
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3585
                     /gene="Lbr"
                     /gene_synonym="C14SR; Nbp60"
                     /note="lamin B receptor; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 30 ESTs, 5 long SRA reads, 11 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 114 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:89789"
                     /db_xref="RGD:620813"
     CDS             153..2018
                     /gene="Lbr"
                     /gene_synonym="C14SR; Nbp60"
                     /codon_start=1
                     /product="delta(14)-sterol reductase LBR isoform X1"
                     /protein_id="XP_038947061.1"
                     /db_xref="GeneID:89789"
                     /db_xref="RGD:620813"
                     /translation="MPSRKFAEGEVVRGRWPGSSLYYEVEILSHDNKSQVYTVKYKDG
                     TELELKESDIKPLKSFKQRKSGSTSSSPSRRRSSRSRSRSRSRSPGRAPKGSRRSVSA
                     SYQADAKEKEMRREILQVKLTPLVLKPFANSVSVYNGEPEHMEKSATPPKNKQERVIL
                     STEDSYIATQYSLRPRREEVKTKNIESEEQNLVTRGPVPLGTFQVTTPQRRDLEFGGV
                     PGALLIMLGLPACVFLLLLQCAQKDPGLLQFPPPLPALRELWEARVCGVYLLWFFLQA
                     LFSLLPVGKVVEGTPLVDGRRLKYRLNGLYAFILTSAAVGTAVFWDIELYYLYTHFLQ
                     FALAAIVFSVVLSVYLYARSLKVPRDELSPASSGNAVYDFFIGRELNPRIGAFDLKFF
                     CELRPGLIGWVVINLVMLLAEMKVQERSAPSLAMTLVNSFQLLYVVDALWFEEALLTT
                     MDIIHDGFGFMLAFGDLVWVPFTYSLQAFYLVNHPQDLSWPLASVIIALKLCGYVIFR
                     CANSQKNAFRKNPTDPKLAHLKTIPTSTGKSLLVSGWWGFVRHPNYLGDLIMALAWSL
                     PCGFNHILPYFYVIYFTALLIHREARDEHQCRRKYGLAWEKYCQRVPYRIFPYIY"
ORIGIN      
        1 acgcgcgctt tgggagcccc ggacggcctg ggctgtgccc gctgtggtgt ccgggcctcc
       61 ggagagccgg cggccttcag gggaagagtt aactgcctct ggcccctgcc gaagcaccgt
      121 cccacctgtc ccggcctcac tgattttgaa aaatgccaag tcggaagttt gctgagggcg
      181 aagtggtcag aggccggtgg cctgggagct ccctgtatta tgaggtagag attctgagcc
      241 atgacaacaa gtcccaggtc tacaccgtaa aatacaaaga tggcaccgag ctggagctga
      301 aggagagtga catcaagcct ttaaagtcct ttaagcagag aaagagtggc tcaacttcca
      361 gctctccttc aagacgccgc agcagccgca gccgctcccg atcacgctcc cgatccccgg
      421 gccgggcacc caaaggttcc agaagatcag tctctgcttc ctaccaggct gacgctaagg
      481 aaaaggaaat gaggagggag attttgcaag ttaaattgac tccgctcgtg ctgaagccgt
      541 ttgcaaacag cgtcagtgtg tacaacgggg agcccgaaca catggaaaag agcgccacac
      601 ctcctaaaaa caagcaggaa agagtcattt tgtcaacaga agacagttat atagctacac
      661 agtacagcct tcgccccaga agagaagagg tcaaaaccaa aaacatagag tccgaggaac
      721 aaaaccttgt caccagagga cctgtacctt tgggaacctt tcaagtgacc actccacaga
      781 ggagggactt ggagttcgga ggagtacctg gtgcgctcct cattatgctt ggcctgcctg
      841 cctgtgtctt cctgctgctg ctgcagtgtg cgcagaagga ccccgggctg ctccagttcc
      901 ctccacctct gccagctctc cgtgagctgt gggaagccag agtgtgtggc gtttacctcc
      961 tctggttctt ccttcaagct ctcttctccc ttctaccagt tgggaaggtt gtagaaggaa
     1021 cacctcttgt tgatggaaga agactcaagt acagactgaa tggactgtat gccttcatcc
     1081 tgacatcagc agccgtgggg acagctgtct tctgggacat agaactatat tacctgtaca
     1141 ctcacttcct gcagtttgca ctggcagcca ttgtgttttc agtggtcctg agtgtttacc
     1201 tctatgcccg ctctttgaaa gtccccaggg atgagctgtc acctgccagt tctggaaatg
     1261 ctgtctatga cttcttcatt ggccgtgagt taaaccctcg aattggtgct ttcgatctca
     1321 agttcttctg tgaattgcgc cctggattga tcggatgggt ggttattaac ttggtgatgc
     1381 ttttggctga aatgaaagtc caggagcgta gtgctccgtc cttggcgatg accctggtca
     1441 acagcttcca gctcctgtat gtggtggacg ccctctggtt tgaggaagca ttgctgacca
     1501 ccatggacat catccacgat ggctttggct tcatgctggc ctttggggat ttagtgtggg
     1561 ttccatttac ctacagtctc caggccttct acctggtcaa ccatccccag gacttgtcct
     1621 ggccattggc ttctgtcatc atcgctctga agctgtgtgg atatgtaata ttccgttgtg
     1681 caaactctca gaaaaatgct tttcggaaga atcccactga tccaaagctt gcacatttga
     1741 agaccatccc tacttcgacg gggaagagtc tgcttgtgtc tggatggtgg ggctttgttc
     1801 gccatcccaa ttacttgggt gatctcatca tggctctggc gtggtccctc ccatgtggct
     1861 tcaaccacat cctgccttac ttctatgtca tctacttcac cgcattgctt atccatcgag
     1921 aagcccgtga tgaacaccag tgcaggagga agtacggcct ggcctgggag aagtactgtc
     1981 agcgcgtgcc ctaccgcata ttcccctaca tttactgacc tgtgccgctt gccccgcagc
     2041 tcagactccc agaaacaagg gaaagtccaa atgaactaac acgatgcact gacaggatct
     2101 ccaggttgtt tctgagtcag gactctagag ccaaatagta catcttttaa tgtagctgga
     2161 tttattctta ttaaagtggc agttaatgta aggtgaaata caagaatgct ataatttgct
     2221 tattaatagg aacattttaa tccctaaaaa tctgaagttt tatttttgta gttttttttt
     2281 tttcagtttt tttccctttt tgcatttgat ttttcttaat tgagatctct taaagtacat
     2341 ctatgtttca ttgtgtttag aacaaattct ttttaagtca gtttattagt ctataaatca
     2401 agcaaaaacc tgcccagtat ttattggtgg tctgtctgaa gaataagggc agatattgca
     2461 ggacctgttg aagggagacc agtcatagca gtgactccac gtcagccttt aaaagtgcat
     2521 ttggaaatgt aaacacagac tagttttatg taatataagg tgacttttgg tttttctgta
     2581 cagtttttga atgtgagata attgtcagaa actaagtagt tttttaacaa aatattttca
     2641 gtgttttaaa ttaagttttg taaagtaatg tgaatttaaa agtataaagg aattacaatt
     2701 catttaaagt taaaatatag gaaagttatt tttctttatc caaagtttgt gaatttggct
     2761 ttgctacctc aatttgcagg tgtgtgtttg cctttataaa ctgttgcaaa tggaaaaaat
     2821 atatttttga gtaagagcaa tatttaaaca tttttacaca catcggtgtt ggaaaattgc
     2881 cattttaggc cactattttt atatattttt tgacttgcaa ttcaacagtg tttttgctac
     2941 tgttagctaa tacaatttat actattttgt atcctttatg tttttagaac tctctagaaa
     3001 ggagttctac ctgatacaac tttttaagtt ttctctctgt ttggtagatg tgcgagcata
     3061 agctggttgt agccattcaa gtctagtgag gttgagtttg acggtaactg tcctggagca
     3121 ggacaagtgg caaattcact agacttttat tcaacgctac attgtcctca gaacctaagg
     3181 atgcatacac atacagtgta tacgtgtggg tttgtttctc ctgcacatat cacatatgag
     3241 ccagatgcag tgttcatcct gtcctgtagc ttagagtata cgcaaagaag ctgtgctcat
     3301 gtaattgcga cgtgtcactc tgcattctgt aactctttac tgtttatgac agtgtcattg
     3361 ttcaatagta ctaaggtgtt catgggggtt tgctatcgtg ctctctcttc tggtatcaac
     3421 atggtgtgtg cccagcagct tagaaggaaa ctttgggtaa gactttgggc tctttgcctg
     3481 gtagtgatag ggcgggccag ggcagtgcca ccatatctgg atatcaggtg caagttgttt
     3541 ttaatatgat ctttggcaag ttttataata aaattttggt cagaa
//
